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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Gold Compounds (3):
Recent article
Gold Compounds
Abstract
Unique, porous gold nanobelts consisting of self-organized nanoparticles were synthesized in a high yield by morphology-preserved transformation from metal-surfactant complex precursor nanobelts formed by a bolaform surfactant dodecane-1,12-bis(trimethylammonium bromide) (N-C(12)-NBr(2)) and HAuCl(4...
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PMID: 20503996
PDF is available here.
PDF is available here.
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Abstract
Gold compounds are well known for their neurological and nephrotoxic implications. However, haematological toxicity is one of the most serious toxic and less studied effects. The lack of information on these aspects of Au(III) prompted us to study the structural effects induced on cell membranes, pa...
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PMID: 20580689
PDF is available here.
PDF is available here.
Abstract
Inkjet printed organic thin films are being used for a variety of electronic and sensor applications with advantages that include ease of fabrication and reproducibility. Construction and use of a low-cost photometer based on a light-emitting diode (LED) light source and a photodiode detector are de...
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PMID: 20370198
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (74)19 2009
Abstract
An efficient protocol was developed for the synthesis of fused heterocyclic multiring compounds pyrrolo[1,2-a]quinolin-1(2H)-ones via a AuBr(3)/AgSbF(6)-catalyzed cascade transformation. Significantly, the strategy affords a straightforward and efficient approach to construction of tricyclic lactam...
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PMID: 19778077
PDF is available here.
PDF is available here.
Abstract
We investigate the nucleation and growth behavior of Au nanocrystals that are mediated by the engineered peptide AYSSGAPPMPPF. Unlike other nanocrystal synthesis schemes, this peptide produces Au nanocrystals from Au(III) ions at very low relative peptide concentrations, at ambient temperature, and...
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PMID: 19630407
PDF is available here.
PDF is available here.
Organic Letters (11)16 2009
Abstract
A formal synthesis of swainsonine has been achieved using a highly efficient and diastereoselective gold(III)-catalyzed allene cyclization.
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PMID: 19719203
PDF is available here.
PDF is available here.
Inorganic Chemistry (48)6 2009
Abstract
In this paper, inhibition of the glutathione peroxidase activity of two synthetic organoselenium compounds, bis[2-(N,N-dimethylamino)benzyl]diselenide (5) and bis[2-(N,N-dimethylamino)benzyl]selenide (9), by gold(I) thioglucose (1), chloro(triethylphosphine)gold(I), chloro(trimethylphosphine)gold(I)...
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PMID: 19267501
PDF is available here.
PDF is available here.
Abstract
The permanent colouring of disfigured corneal scars is known for almost 200 years. Because of improvement in surgical reconstructive techniques, corneal tattoing is used today only with a restricted group on carefully chosen patients, and merely for esthetique reasons.
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PMID: 19697848
PDF is available here.
PDF is available here.
Journal of Physical Chemistry A: Molecules, Spectroscopy, Kinetics, Environment and General Theory (112)46 2008
Abstract
The high-resolution X-ray diffraction analysis and plane-wave density functional theory were applied to the investigation of charge density distribution in the donor-acceptor complex of AuCl with PPh3. The approach allows us to estimate the atomic charges, the charge transfer, the energy of weak int...
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PMID: 18959385
PDF is available here.
PDF is available here.
Abstract
We describe a 22-year-old patient with FMF who was complicated with protracted arthritis in the knee and shoulder joints and bilateral sacroiliitis. He was successfully treated by intramuscular gold 50 mg weekly. However, gold treatment was discontinued 8 months later because of the development of a...
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PMID: 18592246
PDF is available here.
PDF is available here.
Clinical Rheumatology (27)11 2008
Abstract
The primary objective of this double-blind, randomised, controlled trial was to determine if implanting gold beads at five acupuncture points around the knee joint improves 1-year outcomes for patients with osteoarthritis (OA) of the knee. Participants were 43 adults aged 18-80 years with pain and s...
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PMID: 18500437
PDF is available here.
PDF is available here.
Abstract
Nanosized metal and polyaniline (PANi) composite spheres have been prepared via the polymerization of aniline using PdCl(2) or HAuCl(4) as the oxidant in a microemulsion system. The oxidization of aniline and the reduction of metal ion happened together during the reaction, yielding PANi and element...
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PMID: 18674780
PDF is available here.
PDF is available here.
Abstract
A silver- and Brönsted acid-free protocol for generating the (tricyclohexylphosphine)gold(I) cation from the corresponding azide complexes is disclosed. The gold(I) cations so liberated are trapped by complexation with octaethylporphyrin. The first structurally authenticated gold(I) porphyrin compl...
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PMID: 18780788
PDF is available here.
PDF is available here.
Abstract
Gold(I) complexes containing N-heterocyclic carbene ligands were synthesized, characterized, and along with the antiarthritic drug, auranofin, tested as inhibitors of the cysteine-dependent protein tyrosine phosphatases, which are implicated in several disease states. These compounds exhibit potenci...
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PMID: 18605719
PDF is available here.
PDF is available here.
Abstract
Abstract
A simplified synthesis of hollow gold nanoshells 20-50 nm in diameter via the well-established templated galvanic replacement reaction of silver for gold is presented. The surface plasmon resonance absorbance of the nanoshells is tuned using basic colloid chemistry to control the size of the silver...
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PMID: 18623295
PDF is available here.
PDF is available here.
Abstract
We now know that secondary degenerative events contribute to delayed cell death, functional impairment and clinical deterioration. In three experiments, we further characterized the long-term maturation of injury in the collagenase model of striatal ICH in rat. First, we quantified the volume of tis...
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PMID: 18691074
PDF is available here.
PDF is available here.
Inorganic Chemistry (47)14 2008
Abstract
Gold complexes of the type [(AuPEt3)2xspa] were prepared by reacting AuPEt3Cl in basic media with the 3-(aryl)-2-sulfanylpropenoic acids H2xspa [x = p, Clp, -o-mp, -p-mp, -o-hp, -p-hp, diBr-o-hp, f, t, -o-py; p = 3-phenyl, Clp = 3-(2-chlorophenyl)-, -o-mp = 3-(2-methoxyphenyl)-, -p-mp = 3-(4-methoxy...
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PMID: 18563877
PDF is available here.
PDF is available here.
Abstract
We were able to produce Au nanowires with an average diameter of approximately 1.8 nm and an aspect ratio of >1000 in high yields (approximately 70%)....
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PMID: 18540574
PDF is available here.
PDF is available here.
Abstract
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain monodispersed GNPs. Glutamic acid reduced go...
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PMID: 18486946
PDF is available here.
PDF is available here.
Abstract
Peripheral facial nerve palsy (FNP) may (secondary FNP) or may not have a detectable cause (Bell's palsy). Three quarters of peripheral FNP are primary and one quarter secondary. The most prevalent causes of secondary FNP are systemic viral infections, trauma, surgery, diabetes, local infections, tu...
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PMID: 18368417
PDF is available here.
PDF is available here.
Journal of Organic Chemistry (73)12 2008
Abstract
A diversity-oriented approach for the synthesis of structurally diverse catechins was achieved in good yields via thiourea/AuCl(3)/AgOTf-catalyzed annulations of aryl epoxides under mild conditions. This new protocol provides a highly efficient entry to a library of catechins-derived natural product...
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PMID: 18498193
PDF is available here.
PDF is available here.
Biology of the Cell (100)6 2008
Abstract
Our results suggest that mercury inhibits the P(f) of AQP4 by mechanisms different from those for AQP1 and that AQP4 may be gated by modification of a cysteine residue in cytoplasmic loop D....
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PMID: 18167118
PDF is available here.
PDF is available here.
Carcinogenesis (29)6 2008
Abstract
We compare two matched liver progenitor cell (LPC) lines, one non-tumorigenic [p53-immortalized liver (PIL) 4] and the other tumorigenic (PIL2). Analysis of these cell lines and a p53 wild-type non-tumorigenic cell line [bipotential murine oval liver (BMOL)] revealed an increase in expression of gen...
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PMID: 18413365
PDF is available here.
PDF is available here.
Abstract
The large-bite bis(phosphite) ligand [{(-OC(10)H(6)(mu-S)C(10)H(6)O-)P{mu-(-OC(10)H(6)(mu-S)C(10)H(6)O-)}P(-OC(10)H(6)(mu-S)C(10)H(6)O-)}] (Pinsertion markP) () was obtained by the reaction of PCl(3) and thiobis(2,2'-naphthol) (). The stoichiometric reactions of with elemental sulfur and selenium af...
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PMID: 18414753
PDF is available here.
PDF is available here.
Abstract
We employ a combination of experimental and computational investigations into the effect of changes in the phosphine ligand of auranofin on its in vitro inhibition of cathepsin B. Sequential replacement of the ethyl substituents of triethylphosphine by phenyl groups leads to increasing potency in th...
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PMID: 18253767
PDF is available here.
PDF is available here.
Inorganic Chemistry (47)7 2008
Abstract
We have found that the 6,6'-dimethyl-2,2'-bipyridine derivative, which showed the largest structural deviations with respect to the model compound [Au2(mu-O)2(bipy)2](PF6)2, also had the highest oxidizing power, the least thermal stability, and the greatest cytotoxic activity. The positive correlati...
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PMID: 18314951
PDF is available here.
PDF is available here.
Abstract
Microbial precipitation of gold was achieved using Escherichia coli and Desulfovibrio desulfuricans provided with H2 as the electron donor. No precipitation was observed using H2 alone or with heat-killed cells. Reduction of aqueous AuIII ions by both strains was demonstrated at pH 7 using 2 mM HAuC...
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PMID: 17969152
PDF is available here.
PDF is available here.
Abstract
Gold(I) complexes react with 4-allenyl arenes in an exo fashion to furnish vinyl-substituted benzocycles. Phosphite gold(I) monocations were found to be optimal, and the catalyst was tolerant of ethers, esters, and pyrroles. Reactions proceeded in unpurified solvent at room temperature.
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PMID: 18278940
PDF is available here.
PDF is available here.
Abstract
We hypothesize that these metallodrugs, at variance with classical platinum(II) drugs, produce in most cases their growth inhibition effects through a variety of "DNA-independent" mechanisms. Notably, strong inhibition of the selenoenzyme thioredoxin reductase and associated disregulation of mitocho...
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PMID: 18177942
PDF is available here.
PDF is available here.
Abstract
Electrospray ionization spectra of potential cyanide-containing gold-drug metabolites revealed additional, weak, unanticipated peaks at approximately twice the mass of the gold(I) and gold(III) cyanide complexes. The exact masses correspond to proton-linked bimetallic complexes, [H[Au(CN)(m)](2)](-)...
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PMID: 18255157
PDF is available here.
PDF is available here.
Abstract
We have previously shown that analogs of auranofin, a clinically available antiarthritic drug, inhibit cathepsin B. In this study, the extent to which the steric and electronic properties of the phosphine ligand can be modified to obtain enhanced potency against cathepsin B is investigated....
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PMID: 18164406
PDF is available here.
PDF is available here.
Abstract
It is demonstrated herein that the FAD-dependent enzyme glutathione reductase (GR) catalyzes the NADPH-dependent reduction of AuCl4-, forming gold nanoparticles at the active site that are tightly bound through the catalytic cysteines. The nanoparticles can be removed from the GR active site with th...
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PMID: 18166048
PDF is available here.
PDF is available here.
Abstract
We developed a method in preparing size-controllable gold nanoparticles (Au NPs, 2-6 nm) capped with glutathione by varying the pH (between 5.5 and 8.0) of the solution before reduction. This method is based on the formation of polymeric nanoparticle precursors, Au(I)-glutathione polymers, which cha...
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PMID: 18154334
PDF is available here.
PDF is available here.
Clinical Chemistry (54)1 2008
Nanogold catalysis-based immunoresonance-scattering spectral assay for trace complement component 3.
Abstract
Nanogold-labeled anti-C3 had a marked catalytic effect on the reaction of HAuCl(4) and NH(2)OH to form particles, which exhibit a maximum RS peak at 585 nm. The decrease in RS intensity, DeltaI(RS), of the nanocatalytic system was proportional to C3 concentration from 5.0 to 160.0 ng/L. The detectio...
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PMID: 17998268
PDF is available here.
PDF is available here.
Abstract
Gold(I) halides, including AuCl and AuBr, were employed for the first time as precursors in the synthesis of Au nanoparticles. The synthesis was accomplished by dissolving Au(I) halides in chloroform in the presence of alkylamines, followed by decomposition at 60 degrees C. The relative low stability...
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PMID: 18058964
PDF is available here.
PDF is available here.
Abstract
We have investigated gold(III) dithiocarbamates for their anticancer activity and showed that their primary target is the proteasome. Treatment of human breast tumor-bearing nude mice with a gold(III) dithiocarbamate complex resulted in significant inhibition of tumor growth, associated with proteas...
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PMID: 17952862
PDF is available here.
PDF is available here.
Abstract
Journal of Inorganic Biochemistry (102)5-6 2008
Abstract
We survey here the results of research activities carried out in our "Laboratory of Metals in Medicine" (Department of Chemistry, University of Florence) during the last three years, concerning the molecular characterisation of adducts formed between platinum, ruthenium and gold metallodrugs and a f...
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PMID: 18289690
PDF is available here.
PDF is available here.
Abstract
This study illustrates a serious health threat to small-scale goldmine in China and indicates an urgent need for environmental control and disease prevention....
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PMID: 17948247
PDF is available here.
PDF is available here.
Abstract
The novel water soluble bidentate phosphine ligand 1,3-bis(di-2-pyridylphosphino)propane (d2pypp) has been synthesized by a convenient route involving treatment of 2-pyridyllithium with Cl(2)P(CH(2))(3)PCl(2) and isolation in crystalline form as the hydrochloride salt. The synthesis of the precursor...
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PMID: 17992279
PDF is available here.
PDF is available here.
Abstract
Highly dispersed gold nanocrystals decorating silica spheres were prepared from HAuCl4 and NaOH via a deposition-precipitation (DP) process, in which the isoelectric point (IEP) of the substrate was adjusted during sphere synthesis by interaction of the surface with ammonia molecules. Through the sy...
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PMID: 17915900
PDF is available here.
PDF is available here.
Nippon rinsho. Japanese journal of clinical medicine (65 Suppl 8) 2007
Abstract
Nippon rinsho. Japanese journal of clinical medicine (65 Suppl 8) 2007
Abstract
FEBS Letters (581)26 2007
Abstract
We compared the effects of gold ions with those of Cu(I) and Ag(I) on ethylene binding in exogenously expressed ETR1 receptors and on ethylene growth responses in etiolated Arabidopsis seedlings. We find that gold ions also support ethylene binding but, unlike Ag(I), do not block ethylene action on...
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PMID: 17931631
PDF is available here.
PDF is available here.
Journal of Inorganic Biochemistry (101)11-12 2007
Abstract
A simple method for synthesizing gold nanoparticles stabilized by horse spleen apoferritin (HSAF) is reported using NaBH(4) or 3-(N-morpholino)propanesulfonic acid (MOPS) as the reducing agent. AuCl(4)(-) reduction by NaBH(4) was complete within a few seconds, whereas reduction by MOPS was much slow...
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PMID: 17723241
PDF is available here.
PDF is available here.
Abstract
Gold nanoparticles of variable sizes have been prepared by reducing HAuCl(4) with trisodium citrate by Frens' method. It has been found that the gold particles under consideration produce well-ordered aggregates upon interaction with a biomolecule, glutathione in variable acidic pH condition and exh...
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PMID: 17540397
PDF is available here.
PDF is available here.
Abstract
While maintaining anatomical integrity, matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) has allowed researchers to directly probe tissue, map the distribution of analytes and elucidate molecular structure with minimal preparation. MALDI-ion mobility (IM)-orthogonal time-of-f...
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PMID: 17621389
PDF is available here.
PDF is available here.
Abstract
Abstract
Incipient-wetness impregnation of gamma-Al(2)O(3) with HAuCl(4) and subsequent removal of chlorine with NaOH, and deposition-precipitation of HAuCl(4) on TiO(2) at pH 7 resulted in supported Au(3+) species. Time-resolved in situ XAS at the Au L(3) edge showed that the Al(2)O(3)-supported oxidic or h...
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PMID: 17579741
PDF is available here.
PDF is available here.
Abstract
Gold nanoparticles are reported and evaluated as probes for the detection of anticancer drug 5-fluorouracil (5FU). The nature of binding between 5FU and gold nanoparticles via complexation is investigated using ultraviolet visible spectrophotometry, cyclic voltammetry, transmission electron microsco...
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PMID: 17287098
PDF is available here.
PDF is available here.
Abstract
Lichen planus is one of the most common mucocutaneous conditions seen in dental practice. A variety of other conditions known as lichenoid reactions can simulate lichen planus either clinically or histologically. This paper will discuss the more common lichenoid reactions seen in clinical practice a...
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PMID: 17849968
PDF is available here.
PDF is available here.
Abstract
We immunolabeled the membrane proteins caveolin-1 and connexin 43 in mouse cell lines as well as the membrane attached protein tetrachloroethene reductive dehalogenase (PceA) in bacterial cells at freeze-fracture replicas generated by different evaporation parameters. The labeling experiments for ca...
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PMID: 17415584
PDF is available here.
PDF is available here.
Inorganic Chemistry (46)11 2007
Abstract
Potassium N-isopropyl-2-(isopropylamino)troponiminate, K{(iPr)2ATI}, and potassium N-cyclohexyl-2-(cyclohexylamino)troponiminate, K{(Cy)2ATI}, were synthesized by treatment of the neutral ligands with an excess of KH in THF. Reaction of the potassium reagents with [AuClPPh3] resulted in the gold com...
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PMID: 17480072
PDF is available here.
PDF is available here.
Abstract
X-ray absorption near-edge structure spectroscopy (XANES) was successfully employed to determine the gold valence in the metal-reducing bacterium Shewanella algae after exposure to a 1 mM aqueous HAuCl4 solution for 10-120 min. XANES spectra revealed the oxidation state of gold in the bacterial cell...
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PMID: 17630130
PDF is available here.
PDF is available here.
Abstract
We have investigated extracellular biosynthesis of gold nanoparticles using Sargassum wightii and have achieved rapid formation of gold nanoparticles in a short duration. The UV-vis spectrum of the aqueous medium containing gold ion showed peak at 527 nm corresponding to the plasmon absorbance of go...
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PMID: 17350236
PDF is available here.
PDF is available here.
Abstract
This paper proposes an alternative solution to multimetal deposition (MMD) for the development of latent fingermarks on non-porous and porous surfaces. MMD offers a good sensitivity, however it is very time-consuming and requires many reagents to be carried out. Single-metal deposition (SMD) replace...
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PMID: 17275233
PDF is available here.
PDF is available here.
Journal of Microscopy (Oxford) (226)Pt 1 2007
Abstract
Toluidine blue and gold chloride stains are both well-known for staining nervous tissue. Toluidine blue is a general method to stain neurons and glia, used because of the speed of action. Gold sublimate is a delicate procedure that requires extreme purity of reagents and materials, and it stains ast...
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PMID: 17381706
PDF is available here.
PDF is available here.
Abstract
We monitored both morphological and spectral changes as the molar ratio of HAuCl4 to Ag was increased. The details of reaction were different from previous observations on single-crystal Ag nanocubes and cuboctahedrons. Because Au and Ag form alloys rapidly within small MTPs rich in vacancy and grai...
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PMID: 17243691
PDF is available here.
PDF is available here.
Biophysical Journal (92)4 2007
Abstract
We suggest that the CFTR pore has at least two anion binding sites at which Au(CN)2(-) and Pt(NO2)4(2-) block Cl- permeation. The T-338A mutation decreases a barrier for Au(CN)2(-) movement between different sites, leading to significant changes in its blocking action. Our finding that apparent bloc...
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PMID: 17142267
PDF is available here.
PDF is available here.