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Chromium Isotopes (1):
Recent article
Chromium Isotopes
Abstract
We compared autologous and allogeneic CD8(+) T cell responses against RCC line from RCC patients and their HLA-matched donors, using mixed lymphocyte/tumor cell cultures (MLTCs). In addition, we analyzed the expression of molecules associated with cell cycle regulation. Autologous MLTC responder CD8...
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PMID: 20339477
PDF is available here.
PDF is available here.
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Abstract
An isotope dilution method has been developed for the speciation analysis of chromium in natural waters which accounts for species interconversions without the requirement of a separation instrument connected to the mass spectrometer. The method involves (i) in-situ spiking of the sample with isotop...
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PMID: 18804619
PDF is available here.
PDF is available here.
Oncology Reports (19)5 2008
Abstract
These results showed that a combination of Treg cell-depletion using anti-CD25 mAbs and CTL administration is a feasible approach for treatment of cancers which warrants further exploration in the clinical setting....
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PMID: 18425386
PDF is available here.
PDF is available here.
Abstract
In 13 subjects affected by 03B2-thalassaemia major, in three subjects affected by 03B2-thalassaemia minor and in five normal healthy persons haemoglobin synthesis and the survival of red cells transfused into normal, group compatible, healthy recipients has been studied. The existence of an excess of...
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PMID: 4183531
PDF is available here.
PDF is available here.
Abstract
Red-cell survival was studied in eight patients with haemoglobin H disease in the steady state, using simultaneously [51Cr]chromate and [32P]di-iso-propyl phosphofluoridate (DF32P). A shortened survival apparently due to a process of random destruction was observed in all patients, and the rate of 51...
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PMID: 4636191
PDF is available here.
PDF is available here.
Abstract
We synthesised two modified epitopes where the amino acid at position 2 involved in anchoring the peptide to the class I molecule was replaced with the alpha-methylated beta,gamma-unsaturated arginine analogue 2-(S)-amino-5-guanidino-2-methyl-pent-3-enoic acid. The latter was prepared via a multi-st...
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PMID: 17024283
PDF is available here.
PDF is available here.
Abstract
Small intestinal permeability is frequently abnormal in diarrhea-predominant IBS. Those without a history of infectious onset appear to have a more severe defect....
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PMID: 16771951
PDF is available here.
PDF is available here.
Journal of Neuroimmunology (168)1-2 2005
Abstract
We employed a cDNA microarray technique to elucidate how EA alters gene expressions in the spleen of rats. We screened EA responsive genes using a high-throughput screening and identified 154 genes. Among those genes we selected 4 genes that are known to play a crucial role in NK cell activation and...
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PMID: 16154208
PDF is available here.
PDF is available here.
Radiation Protection Dosimetry (115)1-4 2005
Abstract
Neutron capture and transmission measurements were performed by the time-of-flight technique at the Rensselaer Polytechnic Institute LINAC using metallic neodymium samples. The capture measurements were made at the 25-m-long flight station with a 16-segment NaI(Tl) multiplicity detector, and the tra...
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PMID: 16381701
PDF is available here.
PDF is available here.
Radiation Protection Dosimetry (115)1-4 2005
Abstract
The powerful white neutron spectrum from Gelina is used for the investigation of gamma ray production cross sections in the reaction 52Cr(n,n'gamma)52Cr. The gamma rays from the inelastic process are detected with two large volume HPGe detectors placed at 110 degrees and 150 degrees with respect to...
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PMID: 16381700
PDF is available here.
PDF is available here.
Abstract
We investigate effects of sorption during transport of Cr(VI) which may also shift Cr isotopes values, complicating efforts to quantify reduction. This study shows that Cr stable isotope fractionation caused by sorption is negligible. Equilibrium fractionation of Cr stable isotopes between dissolved...
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PMID: 15296311
PDF is available here.
PDF is available here.
Abstract
Spinal Cord (40)10 2002
Abstract
A linear relationship was found between (51)Cr-EDTA-clearance and the reciprocal values of cystatin C and creatinine. The correlation coefficient between (51)Cr-EDTA-clearance and 1/cystatin C was 0.72 compared to the correlation coefficient between (51)Cr-EDTA-clearance and 1/creatinine being 0.26....
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PMID: 12235535
PDF is available here.
PDF is available here.
Abstract
Measurements of chromium (Cr) stable-isotope fractionation in laboratory experiments and natural waters show that lighter isotopes reacted preferentially during Cr(VI) reduction by magnetite and sediments. The 53Cr/52Cr ratio of the product was 3.4 +/- 0.1 per mil less than that of the reactant. 53C...
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PMID: 11896274
PDF is available here.
PDF is available here.
Abstract
Metabolism (50)10 2001
Abstract
We studied alloxan-diabetic rats for the distribution patterns of chromium (Cr), cobalt (Co), iron (Fe), selenium (Se), and zinc (Zn) in the liver, kidney, pancreas, and testes, as well as in the organ subcellular fractions. Normal rats were used as controls. Cr 50-enriched stable isotopic tracer so...
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PMID: 11586488
PDF is available here.
PDF is available here.
Abstract
The removal and recovery of chromium(III) (Cr3+) from aqueous solutions with a spheroidal cellulose adsorbent containing the carboxyl anionic group was investigated. The adsorption of Cr3+ ion on the adsorbent has been found to be time, concentration, pH, and temperature dependent. The adsorption pr...
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PMID: 11561592
PDF is available here.
PDF is available here.
Abstract
We show that mice lacking both granzyme A (gzmA) and granzyme B (gzmB), which are, beside perforin, key constituents of cytolytic vesicles, are as incapable as are perforin-deficient mice of controlling primary infections by the natural mouse pathogen ectromelia, a poxvirus. Death of gzmAxgzmB doubl...
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PMID: 10570179
PDF is available here.
PDF is available here.
Biological Trace Element Research (71-72)1 1999
Abstract
Our new results showed that the nucleic fraction has the highest Cr concentration in the liver cell of both normal and diabetic rats. The diabetic rats retain more Cr in the mitochondrial and lysosomal fractions of liver homogenate than the normal. This is likely an indication of chromium participat...
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PMID: 10676486
PDF is available here.
PDF is available here.
Abstract
Fayalite grains in chondrules in the oxidized, aqueously altered CV3 chondrite Mokoia have large excesses of radiogenic chromium-53. These excesses indicate the in situ decay of short-lived manganese-53 (half-life = 3.7 million years) and define an initial 53Mn/55Mn ratio of 2.32 (+/-0.18) x 10(-6)....
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PMID: 9836631
PDF is available here.
PDF is available here.
Abstract
High-precision mass spectrometric analysis of chromium in sediment samples from the Cretaceous-Tertiary (K-T) boundary coincident with the extinction of numerous organisms on Earth confirms the cosmic origin of the K-T phenomenon. The isotopic composition of chromium in K-T boundary samples from Ste...
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PMID: 9794759
PDF is available here.
PDF is available here.
Abstract
To determine the fate and distribution of chromium during lactation, six lactating women (25-38 y old) were given three doses of the tracer 53Cr (7.55 micromol/d, or 400 microg/d) on days 1, 2, and 3 of the study. Diet records, blood samples taken while subjects were fasting, and 24-h composite milk...
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PMID: 9625101
PDF is available here.
PDF is available here.
Journal of Nutrition (128)1 1998
Abstract
We measured the effects of acute resistive exercise and 16 wk of resistive exercise training on urinary Cr losses of 10 men 53-63 y of age. Subjects consumed diets in compliance with the American Heart Association Phase I diet with a Cr content of 30 +/- 4 microg/d. Sixteen weeks of resistive exerci...
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PMID: 9430605
PDF is available here.
PDF is available here.
Abstract
We demonstrate that blocking the interactions between lymphocyte function associated (LFA)-1 and intercellular adhesion molecule(ICAM)-1 and ICAM-2 completely suppresses Fas-dependent B cell lysis. Antibodies to CD2 and CD48 partially suppress B cell apoptosis, whereas anti-B7.1 and anti-B7.2 antibo...
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PMID: 9314566
PDF is available here.
PDF is available here.
Abstract
We observed that it is possible to measure the total erythrocyte volume using the 50Cr method. Also, the plasma volumes of the splenectomized horses during maximal exercise were found to be slightly smaller than those at rest. On the other hand, in the sham-operated horses, the plasma was decreased...
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PMID: 9342694
PDF is available here.
PDF is available here.
Abstract
Comparison of the two methods led to results that differed on average by 34.5 +/- 45.0 mL (1.8 +/- 2.2%), 0.3 to 3.2%, 95% confidence interval. CONCLUSION: Measurement of red cell volume by use of a stable isotope of chromium is accurate, with potential applications including measurement in pregnant...
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PMID: 9360230
PDF is available here.
PDF is available here.
Clinical Orthopaedics and Related Research ()329 Suppl 1996
Abstract
There has been a resurgence of interest in the use of metal on metal bearings in total hip arthroplasty. Although the use of metal on metal bearing couples would eliminate or substantially reduce particulate polyethylene generation (depending on the presence or absence of polyethylene in the implant...
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PMID: 8769339
PDF is available here.
PDF is available here.
Abstract
Abstract
Isotopic compositions are referred to as anomalous if the isotopic ratios measured cannot be related to the terrestrial (solar) composition of a given element. While small effects close to the resolution of mass spectrometric techniques can have ambiguous origins, the discovery of large isotopic ano...
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PMID: 11541324
PDF is available here.
PDF is available here.
Abstract
Abstract
We report measurements of excess 53Cr--formed by the decay of short-lived 53Mn--in five carbonate fragments from the CI chondrites Orgueil and Ivuna. Our results show that aqueous alteration on small protoplanetary bodies must have begun less than 20 Myr after the time of formation of the oldest kno...
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PMID: 8602215
PDF is available here.
PDF is available here.
Clinical Chemistry (40)1 1994
Abstract
We used an established isotope dilution gas chromatography-mass spectrometry method to measure blood volumes with an enriched stable isotope of chromium. The results were compared with those of the conventional method, which involves radioactive 51Cr. The two methods were compared simultaneously in...
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PMID: 8287547
PDF is available here.
PDF is available here.
Laboratory Investigation (63)5 1990
Abstract
H2O2-mediated cytotoxicity (as measured by 51Cr-release) of rat pulmonary artery endothelial cells was time-dependent and related to the concentration of H2O2 employed. The cytotoxic effects of H2O2 were, as expected, prevented by catalase and the degree of protection was directly related to its tim...
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PMID: 2172653
PDF is available here.
PDF is available here.
Abstract
We examined utilization of selenomethionine (SeMet) and selenite in six lactating (L) and six nonlactating (NL) women, 2-3 mo postpartum, and seven never-pregnant (NP) women by use of stable-isotope tracers. All groups had similar selenium status at the start of the study. Significantly more seleniu...
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PMID: 2403057
PDF is available here.
PDF is available here.
Journal of Endodontics (16)9 1990
Abstract
Gutta-percha (GP) has been the most widely used root canal filling material because of its well-known low toxicity. The inertness of GP, however, was challenged recently. The purpose of this study was to evaluate the toxicity of marketed endodontic GP using the radiochromium release test. Fourteen c...
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PMID: 2098460
PDF is available here.
PDF is available here.
FASEB Journal (4)9 1990
Abstract
We showed that programmed cell death (PCD) in thymocytes is mediated by a sustained increase in cytosolic Ca2+ concentration, resulting in the activation of an endogenous endonuclease, DNA fragmentation, and cell death. In this study we investigated the roles of Ca2+ and DNA fragmentation in target...
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PMID: 2347464
PDF is available here.
PDF is available here.
Abstract
Certain hexavalent chromium (Cr6+) compounds when administered via inhalation at high doses have the potential to induce lung tumors in humans and experimental animals. Trivalent chromium (Cr3+) is an essential human and animal nutrient at levels of 50 to 200 micrograms/day. Recent data have shown t...
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PMID: 2184841
PDF is available here.
PDF is available here.
Abstract
For the measurement of canine blood volume, various experimental conditions and techniques have been investigated using a non radioactive stable isotope 50Cr. On the basis of the results in this preliminary work, erythrocytes were labeled using 50Cr. Five micrograms of 50Cr per 1 ml of blood was adde...
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PMID: 2607738
PDF is available here.
PDF is available here.
Clinica Chimica Acta (181)3 1989
Abstract
Our results suggest that 50Cr can provide a nonradioactive alternative to 51Cr for labeling erythrocytes for life span studies....
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PMID: 2758685
PDF is available here.
PDF is available here.
Abstract
Using 51Cr, 125I, and 59Fe, red cell survival, blood volumes and certain aspects of iron metabolism were investigated in Sierra Leoneans referred for further evaluation of various blood disorders. The data provided clarification of the nature of the anaemia in some patients and demonstrated the haem...
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PMID: 2545089
PDF is available here.
PDF is available here.
Microvascular Research (36)3 1988
Abstract
We continuously measured in blood hematocrit (conductivity cell) and changes in concentration of 125I-HSA (human serum albumin) and 51Cr-labeled red cell (51Cr-RBC; multichannel analyzer) in an extracorporeal circuit. In two additional series of experiments we measured in blood samples changes in pr...
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PMID: 3231125
PDF is available here.
PDF is available here.
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes (39)12 1988
Abstract
The production and radiochemical separation of 52Fe from 4He irradiation of enriched 50Cr target is described. Methods developed for the recovery of the target material (50Cr) are also described. The yield of 52Fe at 38 MeV incident 4He energy is 1667 +/- 133 MBq/C (163 +/- 13 microCi/microAh) at en...
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PMID: 2851001
PDF is available here.
PDF is available here.
Radioisotopes (34)3 1985
Abstract
We have investigated on tagging efficiency of 50Cr to RBC, washing effect and dilution rate by 50Cr content or 51Cr/59Fe ratio. Significant difference was observed in the total blood volume of newborns depending on the delivery style and in addition, it changed dynamically along the time elapsed aft...
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PMID: 4011960
PDF is available here.
PDF is available here.
Abstract
Our data show that NK cells in AIDS and ARC patients are in a less active state compared to those in normals....
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PMID: 3866646
PDF is available here.
PDF is available here.
Abstract
The labelling of blood cells in vitro for subsequent in vivo studies was one of the earliest applications of radioactive tracers in clinical medicine and laid the foundations for many important contributions to the advancement of knowledge of human blood cell pathophysiology. The characteristics req...
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PMID: 6372260
PDF is available here.
PDF is available here.
Radioisotopes (32)5 1983
[Application of PIXE (particle-induced x-ray emission) method to the cytolytic test of tumor cells].
Abstract
We applied PIXE (particle induced X-ray emission) method for the detection of stable chromium (Cr). MM46 cells labelled with natural Cr were treated with anti-MM46 serum and a rabbit complement. The remaining Cr was filtered. The released Cr was precipitated with ethanol and deposited on the filter....
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PMID: 6622755
PDF is available here.
PDF is available here.
Abstract
Single injections of the radiochemicals Cr51-EDTA and I125-ortho-iodohippurate (I125-OH) were used simultaneously to measure the glomerular filtration rate (GFR) and effective renal plasma flow (ERPF), respectively, in 26 calves weighing between 37 kg and 90 kg. The mean GFR was 2.31 ml per minute p...
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PMID: 6789423
PDF is available here.
PDF is available here.
Abstract
An improved technique for the measurement of red cell survival is described in which non-radioactive 50Cr is used in patients for whom radioactive labels are not advisable. The 50Cr was measured by neutron activation analysis using a high resolution germanium (lithium) diode gamma-ray spectrometer....
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PMID: 500836
PDF is available here.
PDF is available here.
Abstract
Abstract
Specific lymphocyte-mediated cytotoxicity to cytomegalovirus (CMV) in eight infants (six to 27 months old) with congenital CMV infection and in the mothers of six of these infants was evaluated with use of a 51chromium (51Cr)-release microassay. The control population consisted of 25...
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PMID: 191541
PDF is available here.
PDF is available here.
Abstract
A comparison of the rates of clearance of 51Cr labelled and 99mTc labelled heat-damaged red cells in 25 patients and 4 control subjects is reported. Very little correlation was found between the clearance half-times of the two types of labelled cells when the cells were labelled with 99mTc prior to...
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PMID: 1031365
PDF is available here.
PDF is available here.
Revista Medica de Chile (104)12 1976
Abstract
Abstract
The survival of 50Cr- and 51Cr-labeled autologous and/or homologous erythrocytes was compared simultaneously in eight pediatric patients and one adult. 50Cr, a stable, nonradioactive nuclide, had values comparable to those of standard radioactive 51Cr labeling. The data also demonstrated the capabil...
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PMID: 984005
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Revista Medica de Chile (103)2 1975
Abstract
Abstract
Forty-four patients with myotonic dystrophy were subjected to various tests for intestinal absorption. A varying number of patients were subjected to the various tests. In one patient (of altogether 11 patients) a pathological vitamin A absorption test was found together with increased faecal excret...
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PMID: 1119317
PDF is available here.
PDF is available here.
Abstract