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Radioisotopes (37):
- Yttrium Radioisotopes
- Sodium Radioisotopes
- Potassium Radioisotopes
- Oxygen Radioisotopes
- Mercury Radioisotopes
- Fluorine Radioisotopes
- Rubidium Radioisotopes
- Nitrogen Radioisotopes
- Krypton Radioisotopes
- Indium Radioisotopes
- Copper Radioisotopes
- Cesium Radioisotopes
- Carbon Radioisotopes
- Sulfur Radioisotopes
- Radioactive Tracers
- Gold Radioisotopes
- Strontium Radioisotopes
- Iodine Radioisotopes
- Chromium Radioisotopes
- Barium Radioisotopes
- Tin Radioisotopes
- Bromine Radioisotopes
- Thallium Radioisotopes
- Selenium Radioisotopes
- Xenon Radioisotopes
- Ruthenium Radioisotopes
- Cobalt Radioisotopes
- Zinc Radioisotopes
- Phosphorus Radioisotopes
- Lead Radioisotopes
- Calcium Radioisotopes
- Iridium Radioisotopes
- Gallium Radioisotopes
- Cadmium Radioisotopes
- Tritium
- Iron Radioisotopes
- Cerium Radioisotopes
Recent article
Radioisotopes
Abstract
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Abstract
We have demonstrated that replacement of the His(6)-tag with the negatively charged histidine-glutamate-histidine-glutamate-histidine-glutamate (HEHEHE)-tag permits purification of Affibody molecules by IMAC, enables labeling with [(99m)Tc(CO)(3)](+), and provides low hepatic accumulation of radioac...
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PMID: 21524142
PDF is available here.
PDF is available here.
Abstract
High specific activity (188)Re required for nuclear medicine is mostly obtained from (188)W/(188)Re generators. As the parent radionuclide (188)W is of low specific activity (<185 GBq/g), a relatively large volume of 0.9% saline is required for the elution of (188)Re. Post-elution concentration is n...
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PMID: 20637645
PDF is available here.
PDF is available here.
Abstract
(103)Rhodium(III) complexes derived from seven acyclic tetradentate N(2)S(2) ligands (one diaminedithiol and six diaminedithioether ligands) have been synthesized and characterized. Structural variations in the ligand include the length of carbon backbone between the coordinating atoms (222; 232; 32...
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PMID: 20890539
PDF is available here.
PDF is available here.
Environmental Research (110)8 2010
Abstract
Environmental Research (110)8 2010
Abstract
Environmental Research (110)8 2010
Abstract
Abstract
The present paper reports a combination of radioanalytical and green methodology for the ultra-trace scale speciation of molybdenum. The differential attitude of iron-doped calcium alginate (Fe-CA) and chitosan biopolymers towards no-carrier-added (93m)Mo radionuclide was studied to develop environm...
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PMID: 20541946
PDF is available here.
PDF is available here.
European Journal of Cancer (46)15 2010
Abstract
Spinal metastases are the most frequently encountered spinal tumour and can affect up to 50% of cancer patients. Both the incidence and prevalence of metastases are thought to be rising due to better detection and treatment options of the systemic malignancy resulting in increased patient survival....
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PMID: 20627705
PDF is available here.
PDF is available here.
Abstract
For determination of cross sections of alpha-particle induced reactions on 99.65% enriched (192)Os, the methods for electrolytic preparation of thin samples and radiochemical separation of radioplatinum were optimized. The excitation functions of the (192)Os(alpha,n)(195m)Pt and (192)Os(alpha,3n) (1...
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PMID: 20538474
PDF is available here.
PDF is available here.
Abstract
The aim of the present study was to establish a reference site and its soil characteristics for use of fallout radionuclides in erosion studies in Slovenia. Prior to this study, no reference site and baseline data existed for Slovenia for this purpose. In the agricultural area of Goricko in East Slo...
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PMID: 20687248
PDF is available here.
PDF is available here.
Anticancer Research (30)10 2010
Abstract
These results indicated that BLI could be used to monitor the growth of tumour. High uptake of (177)Lu-AMBA in PC-3M-luc-C6 tumour-bearing mice by microSPECT/CT imaging can further evaluate the potential of (177)Lu-AMBA therapy for PC-3M-luc-C6 tumours....
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PMID: 21036718
PDF is available here.
PDF is available here.
Abstract
The current way to increase efficacy of cancer therapy is the use of molecular recognition of aberrantly expressed gene products for selective treatment. However, only a fraction of the patients have tumors with a particular molecular target. Radionuclide imaging of molecular targets might help to s...
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PMID: 20497119
PDF is available here.
PDF is available here.
Abstract
We describe the in vitro and in vivo evaluation of DTPA-derivatized lipid-based NP (DTPA-NP) radiolabeled with different radiometals, including (111)In and (99m)Tc, for single-photon emission computed tomography (SPECT), (68)Ga for positron emission tomography (PET), and (177)Lu for therapeutic appl...
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PMID: 19863193
PDF is available here.
PDF is available here.
Abstract
We investigate the effect of varying the glandular/adipose proportion of the breast tissue on dose distributions. The dose to the PTV (skin) decreases (increases) with the increasing adipose proportion inside the breast. In a complete geometry and compared to a TG43-like situation, the average PTV D...
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PMID: 20668347
PDF is available here.
PDF is available here.
Bioanalysis (2)8 2010
Abstract
The dried blood spots (DBS) technique has been actively evaluated as plasma replacement for monitoring drug exposure to support drug development in preclinical/clinical pharmacokinetic and toxicokinetic studies. Plasma samples from some of these studies are typically used for metabol...
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PMID: 21083337
PDF is available here.
PDF is available here.
Journal of Clinical Oncology (28)21 2010
Abstract
Haemophilia (16 Suppl 5) 2010
Abstract
SUMMARY: In spite of the fact that the diagnosis of haemophilia is essentially clinical and laboratory-based, imaging has become an important tool for the evaluation of complications, diagnostic confirmation and/or complementation and therapeutic follow-up in haemophilic arthropathy. Radiography rem...
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PMID: 20590865
PDF is available here.
PDF is available here.
Abstract
Journal of Hazardous Materials (178)1-3 2010
Abstract
Sodium aluminosilicate has been synthesized by solution route for use as a sorbent for various radionuclides. It was characterized by XRD, zeta potential, BET surface area, FTIR spectroscopy and site density measurement. Sorption studies of (137)Cs, (133)Ba and (154)Eu on synthesized sodium aluminos...
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PMID: 20236759
PDF is available here.
PDF is available here.
Nature Materials (9)6 2010
Abstract
We report covalent functionalization of radionuclide-filled single-walled carbon nanotubes and their use as radioprobes. Metal halides, including Na(125)I, were sealed inside single-walled carbon nanotubes to create high-density radioemitting crystals and then surfaces of these filled-sealed nanotub...
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PMID: 20473287
PDF is available here.
PDF is available here.
Nature Materials (9)6 2010
Abstract
Danish medical bulletin (57)6 2010
Abstract
Median follow-up was six weeks (mean 14 weeks). Eleven patients died within the 28 week observation period (ten from terminal disease), and four patients had their observation period truncated. Median pain score was 56.3%, 50.0%, and 50.0% of baseline values at week 4 (n = 20), 16 (n = 10), and 28 (...
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PMID: 20515602
PDF is available here.
PDF is available here.
Abstract
In order to put dose-rates derived in environmental impact assessments into context, the International Commission on Radiological Protection (ICRP) has recommended the structuring of effects data according to background exposure levels. The ICRP has also recommended a suite of reference animals and...
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PMID: 20530863
PDF is available here.
PDF is available here.
Abstract
Dose rate benchmarks are required in the tiered approaches used to screen out benign exposure scenarios in radiological ecological risk assessment. Such screening benchmarks, namely the predicted no-effect dose rates (PNEDR), have been derived by applying, as far as possible, the European guidance d...
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PMID: 20530866
PDF is available here.
PDF is available here.
Abstract
Under the International Atomic Energy Agency (IAEA)'s EMRAS (Environmental Modelling for Radiation Safety) programme, activity concentrations of (60)Co, (90)Sr, (137)Cs and (3)H in Perch Lake at Atomic Energy of Canada Limited's Chalk River Laboratories site were predicted, in freshwater primary pro...
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PMID: 20530860
PDF is available here.
PDF is available here.
Abstract
Abstract
This study evaluated a biodegradable drug delivery system for local cancer radiotherapy consisting of a thermally sensitive elastin-like polypeptide (ELP) conjugated to a therapeutic radionuclide. Two ELPs (49 kDa) were synthesized using genetic engineering to test the hypothesis that injectable bio...
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PMID: 20117157
PDF is available here.
PDF is available here.
Chemical Reviews (110)5 2010
Abstract
Abstract
Actively targeted alpha-particles offer specific tumor cell killing action with less collateral damage to surrounding normal tissues than beta-emitters. During the last decade, radiolabeled peptides that bind to different receptors on the tumors have been investigated as potential therapeutic agents...
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PMID: 20350629
PDF is available here.
PDF is available here.
Abstract
Medical Physics (37)5 2010
Abstract
For internal dose calculations, the AF data reveal that the mineral bone in the rat skeletal system is responsible for significant attenuation of gamma rays, especially at low energies. The photon SAF curves of RBM show that, for photon energies greater than 0.6 MeV, there is an increase in secondar...
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PMID: 20527551
PDF is available here.
PDF is available here.
Medical Physics (37)5 2010
Abstract
The application of a single energy correction factor for Yb-169 TLD based dosimetry would introduce a high degree of measurement uncertainty that may not be reasonable for the clinical characterization of a brachytherapy source; rather, an absorbed dose energy correction function will need to be dev...
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PMID: 20527547
PDF is available here.
PDF is available here.
Neurosurgery (66)5 2010
Abstract
We report a case of cystic spinal cord pilocytic astrocytoma treated with surgical resection and 2 intracavitary injections of rhenium. CLINICAL PRESENTATION: A 22-year-old man presented with low-back pain, saddle dysesthesia, and sphincter and sexual dysfunction. Spinal cord magnetic resonance show...
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PMID: 20404673
PDF is available here.
PDF is available here.
Health Physics (98)5 2010
Abstract
Health Physics (98) 2010
Abstract
The activity concentration of terrestrial (226Ra, 232Th, and 40K) and anthropogenic gamma-emitting radionuclide (137Cs) have been analyzed in 48 soil samples collected from Gilgit, a famous city for mountaineers and tourists in northern Pakistan, at an average altitude of 1,550 m, using gamma-ray sp...
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PMID: 20386195
PDF is available here.
PDF is available here.
Health Physics (98)5 2010
Abstract
High purity germanium in situ gamma ray spectroscopy systems are typically calibrated using pre-calculated tables and empirical formulas to estimate the response of a detector to an exponentially distributed source in a soil matrix. Although this method is effective, it has estimated uncertainties o...
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PMID: 20386196
PDF is available here.
PDF is available here.
Health Physics (98)5 2010
Abstract
These results may contribute to the national and regional data regarding radioactivity levels in domestic fish species....
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PMID: 20386204
PDF is available here.
PDF is available here.
Abstract
Clinical studies demonstrated that partial and complete objective responses in up to 30% of patients can be obtained, with a great survival benefit in treated patients. Side effects may involve the kidney and the bone marrow and are usually mild. Renal protection is used to minimize the risk of a la...
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PMID: 20496546
PDF is available here.
PDF is available here.
Abstract
A recent report of the feasibility of simultaneous PET/MR imaging of the healthy human brain has sparked excitement in the field of neuroimaging because of its potential influence and utility in clinical neuroscience research. The aim of this communication is to discuss the benefits...
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PMID: 19942710
PDF is available here.
PDF is available here.
Abstract
Median extraction fraction in 1st echelon nodes with no or low (<1%) disease burden (n = 21) was 68 (range 23-93)%, significantly higher (p < 0.05) than in diseased 1st echelon nodes (n = 9), in which it was 44 (21-66)%. There was, however, no association between extraction fraction in diseased node...
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PMID: 20141499
PDF is available here.
PDF is available here.
Medical Physics (37)4 2010
Abstract
The dosimetric characteristics of source designs exploiting the low photon energy of 170Tm were studied for potential application in HDR-brachytherapy. Dose-rate distributions were obtained for cylindrical and simplified spherical 170Tm source designs (stainless steel and platinum capsule materials)...
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PMID: 20443484
PDF is available here.
PDF is available here.
Abstract
Photoactivation of nuclear isomer (115m)In with a halflife of 4.48 h occurs by (60)Co gamma-ray irradiation. This is because the resonance gamma-ray absorption occurs at 1078 keV level for stable (115)In, and that energy gamma-rays are produced by Compton scattering of (60)Co primary gamma-rays. In...
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PMID: 20110623
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Soil inventories of anthropogenic radionuclides were investigated in altitudinal transects in 2 French regions, Savoie and Montagne Noire. Rain was negligible in these 2 areas the days after the Chernobyl accident. Thus anthropogenic radionuclides are coming hypothetically only from Global Fallout f...
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PMID: 19969404
PDF is available here.
PDF is available here.
Medical Physics (37)3 2010
Abstract
The data from the Yb-169 HDR source, Model M42, presented in this study show that this source compares favorably with another source of Yb-169, Model 4140, already approved for brachytherapy treatment....
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PMID: 20384248
PDF is available here.
PDF is available here.
Health Physics (98)3 2010
Abstract
The ionizing radiation dose-response relationships for internally deposited radionuclides are examined using data from humans involving Ra and laboratory animal studies involving alpha-emitters Ra, Ra, Ra, Th, Pu, Pu, and Am and beta-emitters Y, Sr, Y, and Ce. Intake routes included ingestion, inhal...
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PMID: 20147792
PDF is available here.
PDF is available here.
Health Physics (98)3 2010
Abstract
Enhancements in radiation detection equipment at border crossings and airports resulted in a report to our institution from a Sm-EDTMP therapy patient who was questioned after triggering radiation alarms. Using a clinical SPECT camera in its service mode, gamma-ray spectroscopy was performed on thre...
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PMID: 20147793
PDF is available here.
PDF is available here.
Abstract
A phosphonate pendant-armed cross-bridged cyclam chelator has been synthesized, complexed to Cu(ii), radiolabeled with (64)Cu under mild conditions, and its biodistribution studied.
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PMID: 20449406
PDF is available here.
PDF is available here.
Abstract
Extracorporeal affinity adsorption treatment is a method that safely and efficiently reduces myelotoxicity associated with RIT. Extracorporeal affinity adsorption treatment allows increased administered activity without increased toxicity, with the aim of increasing the absorbed dose to the tumor. H...
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PMID: 20127949
PDF is available here.
PDF is available here.
Abstract
Immunoconjugates composed of the alpha-emitter (213)Bi and the monoclonal antibody d9MAb specifically target HSC45-M2 gastric cancer cells expressing mutant d9-E-cadherin. These conjugates efficiently killed tumor cells in a nude mouse peritoneal carcinomatosis model. To elucidate th...
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PMID: 19139817
PDF is available here.
PDF is available here.
Abstract
There is a lack of appropriate data on transfer of some radionuclides on many terrestrial biota groups. To expand the available data concentration ratios of (238)U, (226)Ra, (232)Th, (40)K and (137)Cs in mosses are presented in this paper. The relationship between concentration ratios of radionuclid...
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PMID: 19836864
PDF is available here.
PDF is available here.
Abstract
We report the characterization of Pu activity and its isotopic composition in a reference fallout material prepared by the Meteorological Research Institute (MRI), Japan. This material was prepared from samples collected at 14 stations throughout Japan in 1963-1979, with reference values of (137)Cs,...
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PMID: 20022080
PDF is available here.
PDF is available here.
Abstract
The potential of alpha-particle emitters to treat cancer has been recognized since the early 1900s. Advances in the targeted delivery of radionuclides and radionuclide conjugation chemistry, and the increased availability of alpha-emitters appropriate for clinical use, have recently led to patient t...
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PMID: 20080889
PDF is available here.
PDF is available here.
Abstract
We performed targeted radioimmunotherapy with a SWCNT-([(225)Ac]DOTA) (E4G10) construct directed at the tumor vasculature in a murine xenograft model of human colon adenocarcinoma (LS174T). The specific construct reduced tumor volume and improved median survival relative to controls. We also perform...
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PMID: 21042424
PDF is available here.
PDF is available here.
Abstract
Current progress in nanomedicine has exploited the possibility of designing tumor-targeted nanocarriers being able to deliver radionuclide payloads in a site or molecular selective manner to improve the efficacy and safety of cancer imaging and therapy. Radionuclides of auger electron-, alpha-, beta...
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PMID: 20811605
PDF is available here.
PDF is available here.
Abstract
Molecular imaging is a new and evolving field that employs a targeted approach to noninvasively assess biologic processes in vivo. By assessing key elements in specific cellular processes prior to irreversible end-organ damage, molecular tools will allow for earlier detection and intervention, impro...
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PMID: 20012514
PDF is available here.
PDF is available here.
Applied Radiation and Isotopes (68)7-8 2010
Abstract