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Technetium Compounds (3):
Recent article
Technetium Compounds
Anesthesiology (113)6 2010
Abstract
Our results suggest that the addition of PEEP in prone might be less beneficial than in supine and that optimal use of the prone posture requires reevaluation of the applied PEEP....
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PMID: 21068656
PDF is available here.
PDF is available here.
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American Surgeon (76)11 2010
Abstract
We evaluated the accuracy of sentinel node biopsy in this group of patients and compared the results with those in whom the diagnosis of breast cancer was established by core needle biopsy. Eighty patients with early stage breast carcinoma were included into our study. Forty patients had a history o...
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PMID: 21140690
PDF is available here.
PDF is available here.
Abstract
We compared the results between subareolar injection of (99m)Tc-tin colloid and injection of (99m)Tc-phytate. This study included 516 breast cancer patients who underwent surgery between 2001 and 2010. Among the 516 patients, (99m)Tc-tin colloid (37-185 MBq) was administered to 412 patients by subar...
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PMID: 20532977
PDF is available here.
PDF is available here.
Abstract
At least one hotspot was detected in the axillary region in 78 (97.5%) and 79 (98.75%) patients on the early and delayed images, respectively. No extra-axillary drainage was noted in the patients. The number and location of detected hot spots were the same in 77 patients on both image sets. In one p...
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PMID: 20429094
PDF is available here.
PDF is available here.
Lymphology (42)2 2009
Abstract
Our results show that combination of WBBPS with LS can characterize extremity CVMs in patients with high diagnostic accuracy, and may thus be useful for making optimal treatment decisions....
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PMID: 19725272
PDF is available here.
PDF is available here.
Der Pathologe (30)3 2009
Abstract
Cardiac amyloidoses are a heterogeneous group of cardiomyopathies that are resistant to treatment and are associated with a poor outcome. Standard heart failure treatment is usually not well tolerated and the underlying disease remains unaffected. The clinical picture is uncharacteristic. Cardiac am...
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PMID: 19357849
PDF is available here.
PDF is available here.
Melanoma Research (19)2 2009
Abstract
The aim of this study was to describe how metastatic melanoma obstructing lymphatic flow to sentinel nodes can result in a false-negative sentinel node biopsy and to show that the use of ultrasound in conjunction with preoperative lymphoscintigraphy can avoid this potential diagnostic pitfall. A ser...
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PMID: 19262412
PDF is available here.
PDF is available here.
Abstract
The best MSR and image contrast for the first and the consecutive axillary SLNs were found at the AO projection. The longest distance between the injection site and the SLNs and between the two SLNs were observed at the AO views. Although the AO view gave the best results for intramammary SLNs the d...
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PMID: 19650175
PDF is available here.
PDF is available here.
Abstract
We demonstrated (99m)Tc-Tin colloid uptake within the lungs and liver in healthy, mature, miniature pigs. Our observations may be explained by the presence of pulmonary intravascular macrophages (PIMs) closely apposed to the endothelium of the pulmonary capillaries in several animal species, such as...
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PMID: 19567389
PDF is available here.
PDF is available here.
Abstract
Abstract
Although sentinel node (SN) biopsy has been utilized to predict regional lymph node metastasis in patients with melanoma and breast cancer, the validity of the SN hypothesis is still controversial in regard to esophageal cancer. SN mapping for esophageal cancer is relatively complicated compared to...
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PMID: 18696204
PDF is available here.
PDF is available here.
Abstract
Radiolabeling of canine leukocytes in whole blood with (99m)TcSnC has minor adverse effect on their phagocytic function. The radiolabeled canine leukocytes retained a large percentage of radioactivity for at least 7 h postlabeling....
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PMID: 18678356
PDF is available here.
PDF is available here.
Abstract
Malignant colonic polyps can be removed endoscopically but surgical resection is sometimes required. However, the polypectomy site can be difficult to locate. Current methods use various tattooing agents, with varying degrees of success. A new technique using preoperative injection of technetium-99m...
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PMID: 18629395
PDF is available here.
PDF is available here.
Annals of Surgery (247)6 2008
Abstract
An FN SN can occur because of deficiencies in nuclear medicine, surgery, or pathology. qRT can detect "occult" metastatic melanoma in SNs that have been identified as negative by histopathology....
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PMID: 18520228
PDF is available here.
PDF is available here.
Abstract
With the pick-up method, SNs were identified in 23 of 42 patients (54.8%); however, with basin dissection, the detection rate was 96% (48 of 50 patients). The average number of SNs detected by the two methods were 2.1 (range, 0-4) and 3.5 (range, 1-7), respectively. The sensitivities of the two meth...
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PMID: 18503367
PDF is available here.
PDF is available here.
Abstract
Intraorbital injections have a great potential for systemic absorption and should not be considered as local pharmaceutical administration....
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PMID: 18263813
PDF is available here.
PDF is available here.
Abstract
By means of lymphoscintigraphy, 71 of 106 basins were found (67%; 95% confidence interval [CI], 57.2-75.9%). Patients were stratified into the following subgroups: successful (S; all basins visualized), partially successful (PS; some basins visualized), and unsuccessful (U; none visualized). The bod...
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PMID: 18266041
PDF is available here.
PDF is available here.
Abstract
The SLN identification rate was 93.8% (121/129). Fifty-six out of the 121 successfully mapped patients had positive ALN. Eight out of these 56 patients had tumor-free SLN (false-negative rate of 14.3%). The false-negative rate was correlated with larger tumor size (T1-T2 versus T3; P = 0.045) and po...
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PMID: 18311507
PDF is available here.
PDF is available here.
Abstract
Cationic antimicrobial peptides are good candidates for new diagnostics and antimicrobial agents. They can rapidly kill a broad range of microbes and have additional activities that have impact on the quality and effectiveness of innate responses and inflammation. Furthermore, the challenge of bacte...
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PMID: 17786940
PDF is available here.
PDF is available here.
Abstract
Abstract
We report a rare case arising from the proximal fibula, presenting multimodality imaging features. An 18-year-old man presented with a 2-year history of gradually increasing pain and swelling in his left knee. Radiograph showed an area of osteolysis with lobulation. Magnetic resonance (MR) imaging d...
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PMID: 18498038
PDF is available here.
PDF is available here.
Abstract
We conclude that osteoporosis should be included in the differential diagnosis of asymptomatic focal osteolysis of the ribs with rib fractures as a complication of acute cough. The case suggests that focal osteolytic lesions of the ribs may regress over time and become scintigraphically inactive....
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PMID: 19565965
PDF is available here.
PDF is available here.
Abstract
By simply incubating Herceptin (trastuzumab) with [99m Tc(CO)3(OH2)3]+ ion in saline, a significant yield of 99m Tc-labeled trastuzumab was found to be achievable. The effective labeling may be based on that trastuzumab is inherent with endogenous histidine group to which 99m Tc(I) tricarbonyl ion c...
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PMID: 17996452
PDF is available here.
PDF is available here.
Abstract
These results are encouraging for further exploration of their derivatives as imaging agents for Abeta plaques in the brain....
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PMID: 18191400
PDF is available here.
PDF is available here.
Abstract
Abstract
The particle sizes of Nanocoll, Nanocis and Hepatate are very stable throughout their period of validity. For Nanocoll, 95% of particles have a diameter <16 nm, with a mean diameter around 8 nm. There are small (< or =1 nm) but significant variations on the mean diameter depending on the volume of p...
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PMID: 18094639
PDF is available here.
PDF is available here.
Abstract
The asthmatic children who do not respond favorably to the specifically anti-allergic treatment, and also begin their breathlessness crisis preferably at night, are suspicious of suffering gastric-esophagus reflux that stimulate bronchial spasm crisis by means of an aspiration mechanism, or more fre...
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PMID: 19157219
PDF is available here.
PDF is available here.
Abstract
Osteolytic appendicular skeletal lesions in eight-stranded, cold-stunned Kemp's ridley sea turtles (Lepidochelys kempii) were evaluated using radiography and skeletal scintigraphy. Radiographic studies were performed monthly in most animals. Follow-up scintigraphy was performed 45-120 days after the...
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PMID: 18720774
PDF is available here.
PDF is available here.
Abstract
We investigated mammary lymphatic drainage in 25 young female mongrel dogs by intramammary injection of 18.5 MBq of 99mTc-dextran (70,000 Da). Lymph node anatomical referencing was obtained using an external marker, bone scintigraphy, or scintiscanning the body contour. Cranial and caudal thoracic m...
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PMID: 18833961
PDF is available here.
PDF is available here.
Abstract
We have used the CuI-catalyzed cycloaddition of azides and terminal alkynes to synthesise novel ligand systems, in which the 1,2,3-triazole is an integral part of the metal chelating system. A diverse set of bidentate alkyne building blocks with different aliphatic and aromatic backbones and various...
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PMID: 18494020
PDF is available here.
PDF is available here.
Lymphology (40)4 2007
Abstract
We investigated whether baseline lymphscintigraphic findings can predict long-term response to complex physical therapy (CPT) in patients with early stage extremity lymphedema. Twenty patients with unilateral extremity lymphedema of clinical stage I or II underwent CPT after baseline lymphscintigrap...
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PMID: 18365531
PDF is available here.
PDF is available here.
Physiological Measurement (28)12 2007
Abstract
This paper explores the potential of isotope V/Q lung scans to quantify lung disease. Areas of restricted perfusion in subjects with a pulmonary embolus (PE) were identified in 3D reconstructions of V/Q images achieved using anatomical data from the Visible Human Project. From these, the extent of l...
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PMID: 18057511
PDF is available here.
PDF is available here.
Gynecologic Oncology (106)3 2007
Abstract
Gynecologic Oncology (106)3 2007
Abstract
We identified 98 articles, and 23 met the inclusion criteria, comprising a total of 842 patients. Ultimately, 12 studies used the combined technique with a sensitivity of 92% (95% CI: 84-98%). Five studies used 99mTc-colloid, with a pooled sensitivity of 92% (95% CI: 79-98%; p=0.71 vs. combined tech...
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PMID: 17628644
PDF is available here.
PDF is available here.
Abstract
A 55-year-old woman presented with moyamoya disease manifesting as recurrent transient ischemic attacks despite taking aspirin and antihypertensive agent. Angiography showed the characteristic angiographic appearance with bilateral internal carotid artery occlusion and abnormal collateral vessels. L...
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PMID: 17721051
PDF is available here.
PDF is available here.
Abstract
The patients were categorized into two groups according to clinical course. There were 13 patients in the "nonsevere" group and 5 in the "severe." In six out of eight CT anatomical areas the "severe" group had significantly higher scores (P < 0.05 to P < 0.0005). The average number of areas involved...
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PMID: 17666260
PDF is available here.
PDF is available here.
Abstract
Bone scintigraphy revealed 32% (16/50) occult scaphoid fractures and 40% (20/50) occult other fractures. Clinical outcome proved that bone scintigraphy was false positive in five patients and in one case false negative for a scaphoid fracture. CONCLUSION: Bone scintigraphy in combination with protoc...
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PMID: 17307177
PDF is available here.
PDF is available here.
Abstract
I and II) lymph node dissection. However, false negative results - albeit rare in experienced hands - may be a serious limitation. The physician should be familiar with this new technique. This will allow him or her to be more actively involved in the management of breast cancer patients and to unde...
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PMID: 17587354
PDF is available here.
PDF is available here.
Rheumatology (46)6 2007
Abstract
Gynecologic Oncology (105)1 2007
Abstract
Most (85%) of the SLNs were in the inter-iliac territory. Para-aortic or parametrial SLNs were found respectively in 2 patients and common iliac SLNs in 5 patients. Thus 9/25 patients had additional information due to SLN detection. One metastasis and one micrometastasis were detected in SLNs. No pa...
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PMID: 17222894
PDF is available here.
PDF is available here.
Abstract
Preop-LSG was successful in all patients. Mean number of SLN detected was 2 per patient (range, 1 to 4) in the right axilla and 2.2 (range, 1 to 5) in the left. In Po10 days-LSG, SLN detection was successful in 92.3%. Mean number of SLN detected was 2.3 per patient (range, 0 to 7) in the right axill...
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PMID: 17245139
PDF is available here.
PDF is available here.
Abstract
Aim
To examine the relationship between the intensity of the radioactive counts and the presence of tumor metastasis in sentinel lymph nodes (SLNs) in order to correctly identify the number of SLNs to be removed.
Patients and methods
Five hundred three breast cancer patients with successful radio...
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PMID: 17258879
PDF is available here.
PDF is available here.
Abstract
Serum cystatin C, but not serum creatinine or RRI measurement, correlates with GFR in each stage of liver failure and has a significant diagnostic advantage in detecting lower GFR in such cases....
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PMID: 17617033
PDF is available here.
PDF is available here.
Breast Cancer (14)1 2007
Abstract
Stereoscopic imaging delineated more hot axillary lymph nodes compared to routine planar imaging in 8 of 42 patients (19.0%) on anterior view, 5 of 44 patients (11.4%) on lateral view, and 11 of 44 patients (25.0%) on either the anterior or lateral view. Statistically significant differences were ob...
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PMID: 17245002
PDF is available here.
PDF is available here.
Abstract
We studied ten consecutive cT1N0 patients who underwent radical esophagectomy with regional lymph node dissection. On the day before surgery, 99m-Tc tin colloid was injected endoscopically around the primary tumor. Lymphoscintigraphy was also performed about three hours after injection. Immediately...
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PMID: 17573623
PDF is available here.
PDF is available here.
Abstract
The 3 foundations of nuclear medicine are radiation conscious personnel, specific radiopharmaceuticals and equipment. The trend in molecular radiopharmacy is to develop new radiopharmaceuticals targeting peptides and receptors. 99mTc-radiopharmaceuticals give important clinical and molecular informa...
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PMID: 18268893
PDF is available here.
PDF is available here.
Gynecologic Oncology (104)1 2007
Abstract
Subserosal fundal injection of blue dye and the radiocolloid is a poor technique for identifying sentinel lymph nodes in patients with high-risk endometrial cancer....
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PMID: 16963111
PDF is available here.
PDF is available here.
Bioconjugate Chemistry (18)5 2007
Abstract
Bombesin-like peptides are related to several human cancer receptors, including small cell lung, prostate, breast, colon, and pancreatic cancers. Litorin, an amphibian bombesin peptide derivative, is found to stimulate the contraction of smooth muscle, to stimulate gastrin, gastric acid, and pancrea...
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PMID: 17760415
PDF is available here.
PDF is available here.
Bioconjugate Chemistry (18)5 2007
Abstract
Two synthetic procedures for HYNIC oxytocin labeling were developed: one based on an orthogonal protection approach and the other with prelabeled (Boc)HYNIC-(Fmoc) amino acids. Both procedures were compared and applied to the preparation of several HYNIC-oxytocin derivatives where ligand position an...
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PMID: 17665873
PDF is available here.
PDF is available here.
Abstract
Genetic algorithms (GA) were used to develop specific technetium metal-ligand force field parameters for the MM3 force field. These parameters were developed using automated procedures within the program FFGenerAtor from a combination of crystallographic structures and ab initio calculations. These...
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PMID: 16769234
PDF is available here.
PDF is available here.
Cirugia y cirujanos (75)2 2007
Abstract
Most patients with invasive squamous cell carcinoma of the penis do not have inguinal node metastasis at the time of diagnosis and 50% of those having palpable nodes are inflammatory. Penis cancer (PC) treatment implies resection of the primary tumor and inguinal lymphadenectomy; nevertheless, morbi...
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PMID: 17511903
PDF is available here.
PDF is available here.
Abstract
Novel ligands have been obtained from the reaction of 4,4'-dibromomethyl-2,2'-bipyridine with 2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosylthiol, 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosylthiol or 2,3,4,6-tetra-O-acetyl-alpha-D-thioacetylmannopyranoside in which the sugar residues are thioglycosi...
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PMID: 17853516
PDF is available here.
PDF is available here.
Abstract
We are reporting now clearly demonstrate that what was said regarding possible problems in the SLND after TBA was not founded on clinical research and contradicts these five clinical findings....
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PMID: 17659414
PDF is available here.
PDF is available here.
Abstract
It is necessary to harvest radioactive lymph nodes other than the most radioactive. Moreover, efforts to remove every radioactive lymph node will minimize false-negative results....
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PMID: 16626922
PDF is available here.
PDF is available here.
Bulletin du cancer (93)12 2006
Abstract
In comparison with conventional imaging, nuclear medicine offers an original metabolic approach for the assessment of the therapeutic response. Gallium 67, thallium 201, technetium 99m-labeled sestamibi and diphosphonates can be performed for therapeutic response assessment in lymphoma, brain and br...
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PMID: 17182375
PDF is available here.
PDF is available here.
Clinical Nuclear Medicine (31)12 2006
Abstract
According to the results of our study, we conclude that perioareolar intradermal injection of Tc-99m tin colloid combined with peritumoral intraparenchymal injection of blue dye is an accurate and easy method of locating the sentinel node with very high detection rates. It is recommended that the co...
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PMID: 17117076
PDF is available here.
PDF is available here.
Abstract
We studied twenty patients with previously untreated squamous cell carcinomas of the oral cavity and N0 necks. After the peritumoral injection of 99mTc filtered tin colloid preoperatively, lymphoscintigraphy and intraoperative mapping using a gamma detector were performed to localize sentinel nodes....
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PMID: 17043421
PDF is available here.
PDF is available here.
Diseases of the Colon and Rectum (49)10 Suppl 2006
Abstract
Two types of the draining lymph node basin of advanced lower rectal cancer were identified using this method. The concordance between lymph node metastases and the draining lymph node basin is good....
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PMID: 17106816
PDF is available here.
PDF is available here.
Abstract
We carried out phantom imaging studies on small-scale high-resolution PET scanners to estimate the limitations of detection associated with 94mTc and PET. Preliminary studies demonstrate that useful images can be obtained with modern image reconstruction algorithms when using a correction for the ca...
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PMID: 17045173
PDF is available here.
PDF is available here.
Clinical Nuclear Medicine (31)10 2006
Abstract
Our periareolar injection technique using Tc-99m antimony sulfur colloid is able to detect internal mammary lymph nodes in at least 18.0% of patients....
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PMID: 16985361
PDF is available here.
PDF is available here.