Mohammad R Ebrahimkhani,
Fiona Oakley,
Lindsay B Murphy,
Jelena Mann,
Anna Moles,
Maria J Perugorria,
Elizabeth Ellis,
Anne F Lakey,
Alastair D Burt,
Angela Douglass,
Matthew C Wright,
Steven A White,
Fabrice Jaffré,
Luc Maroteaux and
Derek A Mann
Abstract
We report that fibrogenic hepatic stellate cells (HSCs) in the liver are negative regulators of hepatocyte regeneration. This negative regulatory function requires stimulation of the 5-hydroxytryptamine 2B receptor (5-HT(2B)) on HSCs by serotonin, which activates expression of transforming growth fa...
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PMID: 22120177
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