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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Oligonucleotide Array Sequence Analysis (0):
Recent article
Oligonucleotide Array Sequence Analysis
Abstract
The Raf/MEK/extracellular signal-regulated kinase (ERK) pathway participates in many processes altered in development and progression of cancer in human beings such as proliferation, transformation, differentiation, and apoptosis. Kinase suppressor of Ras 1 (KSR1) can interact with v...
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PMID: 21435442
PDF is available here.
PDF is available here.
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Clinical Cancer Research (17)7 2011
Abstract
We aim to develop practical biomarker-based risk score that can predict relapse of gastric cancer after surgical treatment....
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PMID: 21447720
PDF is available here.
PDF is available here.
Abstract
We have found this effect is, in part, a result of down-regulation of the major HIV-1 coreceptor, CXCR4. Using a combination of biochemical approaches, our results show that CXCR4 protein and mRNA levels were reduced significantly following KOR activation. We evaluated the nature of the signaling pa...
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PMID: 21447649
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
A total of 29 cases of diffuse large B-cell lymphoma initially manifesting in the bone marrow (BM-DLBCL) were analyzed for V(H) gene sequence, and expression microarray of chemokines and chemokine receptors and immunohistochemical analysis were done. Seminested polymerase chain reaction (PCR) and seq...
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PMID: 21411777
PDF is available here.
PDF is available here.
Abstract
Our observations suggest a common genetic origin of BSCC and carcinosarcoma....
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PMID: 21411780
PDF is available here.
PDF is available here.
Abstract
We screened 125 primary tumors for RAF fusion genes and mutations in KRAS, NRAS, HRAS, PTPN11, BRAF and RAF1. Using microarray-based comparative genomic hybridization (aCGH), we identified in three cases an interstitial deletion of ~2.5 Mb as a novel recurrent mechanism forming BRAF gene fusions wit...
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PMID: 21424530
PDF is available here.
PDF is available here.
Abstract
We developed a rapid and accurate method for the detection of Vibrio parahaemolyticus strains, using multiplex PCR and DNA-DNA hybridization. Multiplex PCR was used to simultaneously amplify three diagnostic genes (tlh, tdh and fla) that serve as molecular markers of V. parahaemolyticus. Biotinylate...
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PMID: 21477785
PDF is available here.
PDF is available here.
Clinical Cancer Research (17)6 2011
Abstract
To analyze the role and translational potential for hypermethylation of CpG islands and shores in the regulation of small RNAs within urothelial cell carcinoma (UCC). To examine microRNAs (miR) and mirtrons, a new class of RNA located within gene introns and processed in a Drosha-independent manner....
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PMID: 21138856
PDF is available here.
PDF is available here.
Cell Host & Microbe (9)3 2011
Abstract
We have determined that Gat201 controls the mRNA levels of ∼1100 genes (16% of the genome) and binds the upstream regions of ∼130 genes. Seven Gat201-bound genes encode for putative and known transcription factors--including two previously implicated in virulence--suggesting an extensive regulat...
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PMID: 21402362
PDF is available here.
PDF is available here.
Abstract
Abstract A potential factor leading to the spread of antimicrobial resistance (AR) in bacteria is the horizontal transfer of resistance genes between bacteria in animals or their environment. To investigate this, swine fecal samples were collected on-farm and cultured for Escherichia...
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PMID: 21385089
PDF is available here.
PDF is available here.
Abstract
Our objective was to analyze gene expression pattern in muscles from patients with amyotrophic lateral sclerosis (ALS) and multifocal motor neuropathy (MMN) compared to controls. Biopsied skeletal muscles from three ALS, three MMN and three control subjects had total RNA extracted and subjected to g...
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PMID: 21375368
PDF is available here.
PDF is available here.
Clinical Cancer Research (17)6 2011
Abstract
Presence of pelvic lymph node metastases is the main prognostic factor in early-stage cervical cancer patients, primarily treated with surgery. Aim of this study was to identify cellular tumor pathways associated with pelvic lymph node metastasis in early-stage cervical cancer.
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PMID: 21385933
PDF is available here.
PDF is available here.
Abstract
We show that mature SLE neutrophils are primed in vivo by type I IFN and die upon exposure to SLE-derived anti-ribonucleoprotein antibodies, releasing neutrophil extracellular traps (NETs). SLE NETs contain DNA as well as large amounts of LL37 and HMGB1, neutrophil proteins that facilitate the uptak...
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PMID: 21389264
PDF is available here.
PDF is available here.
Abstract
We performed a genome-wide gene expression analysis on tumor cell lines established from pleural effusions (malignant pleural mesothelioma and lung ADCA). This analysis led to the identification of genes encoding novel and pertinent cellular and soluble markers, for which the expression was validate...
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PMID: 21356356
PDF is available here.
PDF is available here.
Abstract
We found strong evidence of expression discordance at birth: in both cell types and some evidence for higher discordance in twin pairs with separate: placentas. Genes previously defined as being involved in response to the external: environment showed the most variable expression within pairs, indep...
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PMID: 21358273
PDF is available here.
PDF is available here.
Abstract
We investigated the changes in microRNA (miRNA) expression profiles of chronic TLE rat models. MiRNAs microarray analysis results showed that 125 miRNAs were detected in the hippocampus of lithium-pilocarpine-induced TLE rats and normal rats. Compared with normal rats (control group), 23 of the 125...
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PMID: 21376023
PDF is available here.
PDF is available here.
Abstract
We show that the biochemical pathways associated with tumour cell chemosensitivity to platinum-based drugs are highly coincident, i.e. they describe a consensus phenotype. Direct integration of metabolome and transcriptome data at the point of pathway analysis improved the detection of consensus pat...
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PMID: 21483477
PDF is available here.
PDF is available here.
Abstract
We prepared a fat-soluble extract from persimmon peel (PP) and fed type 2 diabetic Goto-Kakizaki (GK) rats an AIN-93G rodent diet supplemented with persimmon peel extract (PP diet) for 12 weeks. Compared with the control AIN-93G diet, the PP diet significantly reduced plasma glutamic-pyruvate transa...
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PMID: 21370910
PDF is available here.
PDF is available here.
Abstract
We have utilized a spliceoform-specific microarray and polymerase chain reaction to evaluate all known splice variants in human pancreatic cancer cell lines representing a spectrum of differentiation, from near-normal HPDE6 to Capan-1 and poorly differentiated MiaPaCa2 cells. Validation of altered s...
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PMID: 21178653
PDF is available here.
PDF is available here.
Journal of Proteomics (74)3 2011
Abstract
We here proposes a Partial Least Squares Regression (PLSR)-based data integration strategy, which allows simultaneous analysis of proteomic data, gene expression data and classical clinical parameters. PLSR collapses multidimensional data into fewer relevant dimensions for data interpretation. PLSR...
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PMID: 21075225
PDF is available here.
PDF is available here.
Systems Biology, IET (5)2 2011
Abstract
Many methods had been developed on inferring transcriptional network from gene expression. However, it is still necessary to design new method that discloses more detailed and exact network information. Using network-assisted regression, the authors combined the averaged three-way mu...
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PMID: 21405197
PDF is available here.
PDF is available here.
FEBS Letters (585)6 2011
Abstract
We investigated the involvement of microRNAs in oxLDL accumulation and inflammatory response in macrophages. The expression of miR-146a decreases under oxLDL stimulation. MiR-146a significantly reduces intracellular LDL cholesterol content and secretion of interleukin 6, interleukin 8, chemokine (C-...
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PMID: 21329689
PDF is available here.
PDF is available here.
Abstract
To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including, ascertain genes, functional categories and pathways that play a central role in the pathogenesis of BA, and identify the novel prognostic markers for BA.
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PMID: 21390152
PDF is available here.
PDF is available here.