Abstract
Hemodynamic control can improve the outcome of surgery. Esophageal Doppler monitoring measures blood flow by ultrasound waves. This work investigates the cost-effectiveness of this procedure during colorectal resection.
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PMID: 21914501
PDF is available here.
Zubin J ZJ Eapen,
Eric D ED Peterson,
Gregg C GC Fonarow,
Gillian D GD Sanders,
Clyde W CW Yancy,
Samuel F SF Sears,
Mark D MD Carlson,
Anne B AB Curtis,
Laura Lee LL Hall,
David L DL Hayes,
Adrian F AF Hernandez,
Michael M Mirro,
Eric E Prystowsky,
Andrea M AM Russo,
Kevin L KL Thomas and
Sana M SM Al-Khatib
Abstract
Sudden cardiac arrest (SCA) is the most common cause of death in the United States. Despite national guidelines, patients at risk for SCA often fail to receive evidence-based therapies. Racial and ethnic minorities and women are at particularly high risk for undertreatment. To addres...
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PMID: 21835281
PDF is available here.
Abstract
Abstract Interdisciplinary care management is advocated for optimal care of patients with many types of chronic illnesses; however, few models exist that have been tested using randomized trials. The purpose of this report is to describe the theoretical basis for the After Discharge...
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PMID: 21323461
PDF is available here.
Abstract
Upper endoscopy with Bx for EoE appears to be a cost-effective approach in patients when the prevalence of EoE is 8% or greater.Am J Gastroenterol advance online publication, 29 March 2011; doi:10.1038/ajg.2011.94....
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PMID: 21448144
PDF is available here.
Abstract
In soft tissue sarcoma, better distinction of high-risk and low-risk patients is needed to individualize treatment and improve survival. Prognostic systems used in clinical practice identify high-risk patients based on various factors, including age, tumor size and depth, histological type, necrosis,...
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PMID: 21381015
PDF is available here.
Abstract
Multimodality therapy in selected patients with peritoneal carcinomatosis is gaining acceptance. Treatment-directing decision support tools are needed to individualize care and select patients best suited for cytoreductive surgery +/- hyperthermic intraperitoneal chemotherapy (CRS +/...
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PMID: 21337884
PDF is available here.
Abstract
The aim of the project was to compare different screening rules and/or referral cut-offs for the identification of children with disorders of short stature. We undertook an update of a previous systematic review and economic model that addressed the same question.
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PMID: 21356163
PDF is available here.
Abstract
Crohn's disease (CD) is a severe, lifelong disease characterised by inflammation of the gastrointestinal mucosa. The impact on patients and society is high as ill health can be lifelong and can negatively affect patients' quality of life. Costs to the NHS are high, particularly for patients needing h...
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PMID: 21291629
PDF is available here.
Abstract
We built a model to explore how the inclusion of patients with do-not-attempt-resuscitation orders affects intraparenchymal hemorrhage prognostic models.
Retrospective, observational cohort study from May 2001 until September 2003.
University-affiliated tertiary referral hospital in Seattle, WA.
Fou...
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PMID: 21037471
PDF is available here.
Abstract
Psychological disorders have kept away and incapacitated professionals in different sectors of activities. The most serious problems may be associated with various types of pathologies; however, it appears, more often, as psychotic disorders, mood disorders, anxiety disorders, antisocial personality,...
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PMID: 21431598
PDF is available here.
Abstract
Our system has been validated clinically with the real patient data obtained from the Infant Surgery Service in the hospital of Robert Debré in Paris. Our CADS is a good solution to compare the studies of the clubfeet deformities before and after the treatment using a universally scoring system. Th...
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PMID: 21431604
PDF is available here.
Abstract
In the present work, authors have developed a treatment planning system implementing genetic based neuro-fuzzy approaches for accurate analysis of shape and margin of tumor masses appearing in breast using digital mammogram. It is obvious that a complicated structure invites the problem of over learn...
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PMID: 21431593
PDF is available here.
Abstract
Variations in health state utilities can impact cost-effectiveness analyses. One potential source of error is when joint health state (JS) utilities are rated higher than the embedded single state (SS) utilities. Knowing when and in whom this occurs can improve cost-effectiveness analyses.
Men (n =...
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PMID: 21150801
PDF is available here.
Abstract
Several guidelines to reduce cardiovascular risk in diabetes patients exist in North America, Europe, and Australia. Their ability to achieve this goal efficiently is unclear.
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PMID: 21283569
PDF is available here.
Abstract
To compare birth recommendations for pregnant women with a prior cesarean produced from a decision model using absolute risks vs. one using subjective interpretation of the same risks: (1) a multiattribute decision model based on patient prioritization of risks (subjective risk) and (2) a hybrid mod...
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PMID: 20558035
PDF is available here.
Abstract
We applied two updating methods to determine whether adjusting the weights of the predictors or adding new predictors could further improve the accuracy of the diagnostic score. The weights of the predictors did not need to be adjusted, but inclusion of 'history of DVT' and 'prolonged travelling' si...
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PMID: 20886183
PDF is available here.
Abstract
Hib vaccine has gradually been introduced into more and more countries during the past two decades, partly due to GAVI Alliance support to low-income countries. However, since Hib disease burden is difficult to establish in settings with limited diagnostic capacities and since the vaccine continues t...
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PMID: 21720546
PDF is available here.
Abstract
Choosing the appropriate treatment for grade IIIB and IIIC open tibial fractures is a difficult decision for both the patient and the physician. Current research shows that the functional outcomes for reconstruction are similar to those for below-knee amputation, but little investigation of the qual...
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PMID: 20697318
PDF is available here.
Abstract
Our data show SNM to be an efficient investment with an acceptable incremental cost-effectiveness ratio and a limited impact on the total allocated budget for fecal incontinence....
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PMID: 21178862
PDF is available here.
Abstract
In the United States, 192,000 men were diagnosed as having prostate cancer in 2009, the majority with low-risk, clinically localized disease. Treatment of these cancers is associated with substantial morbidity. Active surveillance is an alternative to initial treatment, but long-term outcomes and ef...
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PMID: 21119084
PDF is available here.
Abstract
I (conventional versus decision tree model), taking into account the costs of the distraction, tracheostomy, hospital stay, diagnostic studies, physician fees, and emergency department visits, the total per patient treatment cost was 1.5 greater in the conventional treatment group ($332,673) compare...
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PMID: 20639799
PDF is available here.
Abstract
Conventional computer-assisted detection (CADe) systems in screening mammography provide the same decision support to all users. The aim of this study was to investigate the potential of a context-sensitive CADe system which provides decision support guided by each user's focus of attention during vi...
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PMID: 21158284
PDF is available here.
Abstract
Occupational therapists use a range of types and sources of information when making clinical decisions. It is unclear how this information is integrated.
This paper describes an exploratory qualitative case study that identified the types and sources of information accessed by one experienced paedia...
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PMID: 21090066
PDF is available here.
Lars Budäus,
Markus Graefen,
Georg Salomon,
Hendrik Isbarn,
Giovanni Lughezzani,
Maxine Sun,
Felix K H Chun,
Thorsten Schlomm,
Thomas Steuber,
Alexander Haese,
Jens Koellermann,
Guido Sauter,
Margit Fisch,
Hans Heinzer,
Hartwig Huland and
Pierre I Karakiewicz
Abstract
To examine the rate of Gleason sum upgrading (GSU) from a sum of 6 to a Gleason sum of ≥7 in patients undergoing radical prostatectomy (RP), who fulfilled the recommendations for low dose rate brachytherapy (Gleason sum 6, prostate-specific antigen ≤10 ng/mL, clinical stage ≤T2a and prostate v...
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PMID: 20812920
PDF is available here.
Abstract
In order to decide whether a new treatment should be used in patients, a robust estimate of efficacy and toxicity is no longer sufficient. As a result of increasing healthcare costs across the globe healthcare payers and providers now seek estimates of cost-effectiveness as well. Most trials current...
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PMID: 20655197
PDF is available here.
Abstract
Clinical decision rules can aid in referral decisions for ultrasonography in patients suspected of having deep venous thrombosis (DVT), but physicians are not always convinced of their usefulness and rely on their own judgement.
To compare the performance of a clinical decision rule with the probabi...
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PMID: 20883623
PDF is available here.
Abstract
Alveolar ridge defects resulting from tooth loss, trauma, periodontal disease, or congenital lesions often require correction prior to dental implant therapy. Numerous classifications proposed to describe alveolar ridge defects have been limited to describe intra-arch relationships. To provide suffi...
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PMID: 20814606
PDF is available here.
Abstract
We excluded visits to first-year residents. Patients were asked about their attitudes toward technology use in the exam room using a previously validated 16-item structured questionnaire on patient attitudes toward technology use in the exam room.
The response rate was 97%. Survey results showed mos...
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PMID: 20927673
PDF is available here.
Abstract
A clinical decision tree included age and systolic blood pressure (sensitivity 89.3%, specificity 37.4%, and positive predictive value (PPV) 48.0%), while a tree based on clinical and laboratory data included fasting glucose and systolic blood pressure (sensitivity 89.7%, specificity 54.6%, and PPV...
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PMID: 20693184
PDF is available here.
Abstract
We know as disease". Accordingly, the traditional methods of medicine are not always best for all patients. Over the last decade, the study of genomes and their derivatives (RNA, protein and metabolite) has rapidly advanced to the point that genomic research now serves as the basis for many medical...
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PMID: 21034525
PDF is available here.
Abstract
We estimated the intervention effect using electronic medical record data and hierarchical linear models. The intervention was a PST displaying "care gaps" and recommendations for glycosylated hemoglobin, low-density lipoprotein cholesterol, and blood pressure screening and control; retinopathy, nep...
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PMID: 20964477
PDF is available here.
Abstract
Abstract Objective. To assess the cost-effectiveness of using human papillomavirus testing (HPV triage) in the management of women with minor cytological abnormalities in Sweden. Design. An economic analysis based on a clinical trial, complemented with data from published meta-analys...
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PMID: 20846064
PDF is available here.
Abstract
The fusion of fuzzy local binary patterns and fuzzy grey-level histogram features is more effective than the state of the art approaches for the representation of thyroid ultrasound patterns and can be effectively utilized for the detection of nodules of high malignancy risk in the context of an int...
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PMID: 20427164
PDF is available here.
Abstract
The paper describes a classification system detecting the voluntary movement initiation time and adaptable to different signals. By using a set of features directly derived from raw data, we obtained promising results. Furthermore, although the technique has been developed within the scope of isomet...
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PMID: 20510593
PDF is available here.
Abstract
We have developed a CADx system for evaluation of pulmonary nodule based on a two-step feature selection and ensemble classifier algorithm. We have shown that by combining classifier ensemble algorithms in this two-step manner, it is possible to predict the malignancy for solitary pulmonary nodules...
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PMID: 20570118
PDF is available here.
Abstract
Decisions and treatment should be tailored to each individual patient and to the specific characteristics of patients. A number of available predictive models represent a tool to provide accurate prediction of cancer natural history and to improve patients' care.
(c) 2010 Wiley-Liss, Inc....
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PMID: 20623635
PDF is available here.
Judith Fifield,
Julia McQuillan,
Melanie Martin-Peele,
Vitaly Nazarov,
Andrea J Apter,
Thomas Babor,
Joseph Burleson,
Robert Cushman,
Jeri Hepworth,
Eric Jackson,
Susan Reisine,
Joseph Sheehan and
Joan Twiggs
Abstract
I enrollment period than providers at comparison sites (exp(B) = 2.351, confidence interval [CI] = 1.315-4.204). In Phase II (the post-enrollment visit period), hierarchical linear models (HLMs) and latent growth curves were used to show that asthma control improved significantly by .19 (SE = .05) o...
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PMID: 20812783
PDF is available here.
Abstract
One approach to clinical decision-making requires the integration of the best available research evidence with individual clinical expertise and patient values, and is known as evidence-based medicine (EBM). In clinical decision-making with the current best evidence, systematic reviews have an impor...
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PMID: 20523217
PDF is available here.
Abstract
We present a 6-step model for shared decision-making in decisions about genital surgery for disorders of sex development: (1) Set the stage and develop an appropriate team; (2) Establish preferences for information and roles in decision-making; (3) Perceive and address emotions; (4) Define concerns...
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PMID: 21073122
PDF is available here.
Abstract
Results show that it is not possible to predict grade III-V vesicoureteral reflux reliably using the clinical decision rule. The recent guidelines recommending a search for reflux after a urinary tract infection in children cannot be revised using this decision rule.
Copyright (c) 2010 American Urol...
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PMID: 20488488
PDF is available here.
Bart L Loeys,
Harry C Dietz,
Alan C Braverman,
Bert L Callewaert,
Julie De Backer,
Richard B Devereux,
Yvonne Hilhorst-Hofstee,
Guillaume Jondeau,
Laurence Faivre,
Dianna M Milewicz,
Reed E Pyeritz,
Paul D Sponseller,
Paul Wordsworth and
Anne M De Paepe
Abstract
We anticipate that these new guidelines may delay a definitive diagnosis of MFS but will decrease the risk of premature or misdiagnosis and facilitate worldwide discussion of risk and follow-up/management guidelines....
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PMID: 20591885
PDF is available here.
Abstract
Among Medicare beneficiaries, glaucoma diagnosis not found to be associated with significant risk of comorbidities before development of visual impairment. Further study is necessary to consider the impact of glaucoma on quality of life, as well as aspects of physical and visual function not capture...
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PMID: 20493465
PDF is available here.
Abstract
Comparative effectiveness research (CER) has assumed an increasing role in drug coverage and, in some cases, pricing decisions in Europe, as decision-makers seek to obtain better value for money. This issue brief comparatively examines the use of CER across six countries--Denmark, England, France, G...
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PMID: 20614655
PDF is available here.
Abstract
Pharmacology decision making requires clinical judgment. The authors created interactive microsimulation applying drug information to varying patients' situations. The theory-based microsimulation requires situational analysis for each scenario. The microsimulation uses an interactive format that al...
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PMID: 20411862
PDF is available here.
Abstract
We have seen an increasing trend of foreign data as part of clinical trial data submitted in new drug applications (NDA) to US Food and Drug Administration (FDA). To understand the design and analysis characteristics, we studied schizophrenia multi-regional clinical trials (MRCTs). The schizophrenia...
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PMID: 20872622
PDF is available here.
Abstract
Models developed from pre-transplant characteristics poorly predict long-term survival. Models for separate diseases and 1-year conditional models did not improve prediction. Better databases and approaches to predict survival are needed to improve lung allocation....
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PMID: 20382034
PDF is available here.