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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Embryo Research (1):
Recent article
Embryo Research
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Nature Biotechnology (28)10 2010
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The challenges before science and medicine are these: science must explore the natural world as thoroughly as possible, while still honoring, protecting, serving and preserving the subject of its investigations, and the human beings for whom it is a tool; medicine must confront disease and disabilit...
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PMID: 20693959
PDF is available here.
PDF is available here.
Abstract
We report the first Canadian hESC lines to be generated from cryopreserved embryos and we discuss how we navigated through the Canadian regulatory process. The cryopreserved human zygotes used in this study were cultured to the blastocyst stage, and used to isolate ICM via microsurgery. Unlike previ...
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PMID: 20555390
PDF is available here.
PDF is available here.
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We report our experience of efficient derivation of three new Chinese hES cell lines (SHhES2, SHhES3, and SHhES4) from in vitro fertilization discarded embryos donated by women with polycystic ovary syndrome. These cell lines were derived under conditions minimizing exposure to animal components and...
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PMID: 20186511
PDF is available here.
PDF is available here.
Abstract
We present the derivation and characterization of 15 hESC lines established at the Vrije Universiteit Brussel, Belgium in collaboration with the Universitair Ziekenhuis Brussel, Belgium, using surplus in vitro fertilization embryos and embryos carrying monogenic disorders donated for research. Four...
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PMID: 20224973
PDF is available here.
PDF is available here.
Abstract
We had earlier reported the derivation and characterization of two new sibling human embryonic stem cell lines BJNhem19 and BJNhem20, from discarded grade III embryos of Indian origin. We report here the characteristics of the two sibling cell lines after long-term continuous culture for over 2 yr d...
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PMID: 20178003
PDF is available here.
PDF is available here.
Abstract
We derived and characterised five new cell lines for use in a non-clinical setting. Analysis of clinical data showed that the majority of embryos (94.5%) failed to reach the blastocyst stage of development and of all embryos, regardless of developmental status, 248 embryos were needed to create one...
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PMID: 20198448
PDF is available here.
PDF is available here.
Abstract
The Singapore Stem Cell Bank has generated human embryonic stem cell banks from clinical-grade cell lines ESI-017, ESI-035, ESI-049, and ESI-053. All banks were prepared and characterized according to principles of Good Laboratory Practice for quality assurance. Importantly, each cell line has clear...
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PMID: 20177998
PDF is available here.
PDF is available here.
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We report here the derivation of two new human embryonic stem cell lines, Man-1 and Man-2, and their full characterization as novel pluripotent stem cell lines. Man-1 was derived from an embryo surplus to requirement from routine IVF, while Man-2 was obtained from an oocyte classified as failed to f...
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PMID: 20177994
PDF is available here.
PDF is available here.
Modern Healthcare (40)12 2010
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Persons with serious and disabling medical conditions have traveled abroad in search of stem cell treatments in recent years. However, weak or nonexistent oversight systems in some countries provide insufficient patient protections against unproven stem cell treatments, raising concerns about exposu...
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PMID: 20506693
PDF is available here.
PDF is available here.
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We invite others to join the effort, both in this particular project and in joining together in digital collection, archiving, and knowledge generation at the borders of biology and history....
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PMID: 20503717
PDF is available here.
PDF is available here.
British Journal of Nursing (19)19 2010
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The Government has confirmed that the Human Fertilisation and Embryology Authority is to be abolished with a number of its functions transferred to other bodies as part of the 'bonfire of the quangos'. This article explores these proposals and questions whether such wide-scale reform is an appropria...
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PMID: 21042256
PDF is available here.
PDF is available here.
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While society debates whether and how to use public funds to support work on human embryonic stem cells (hESCs), many scientific groups and businesses debate a different question - the extent to which patents that cover such stem cells should be permitted to limit or to tax their research. The Wisco...
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PMID: 20579254
PDF is available here.
PDF is available here.
Abstract
Embryonic stem cells are actively debated in political and public policy arenas. However, the connections between stem cell innovation and overall health care policy are seldom elucidated. As with many controversial aspects of medical care, the stem cell debate bridges to a variety of social convers...
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PMID: 20579256
PDF is available here.
PDF is available here.
Abstract
Harvesting human embryonic stem (hES) cells is a highly controversial field of research because it rests on the destruction of human embryos. Altering the procedure of nuclear transfer (NT) is suggested to generate hES cell lines without ethical obstacles by claiming that no embryo w...
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PMID: 21644429
PDF is available here.
PDF is available here.
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The controversy over the creation of admixed human-nonhuman embryos, and specifically of what have been termed "cybrids," involves a range of ethical and political issues. It is not reducible to a single question. This paper focuses on one question raised by that controversy, whether...
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PMID: 21644432
PDF is available here.
PDF is available here.
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In the context of stem cell research, the promise of economic growth has become a common policy argument for adoption of permissive policies and increased government funding. However, declarations of economic and commercial benefit, which can be found in policy reports, the scientific literature, pu...
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PMID: 20579253
PDF is available here.
PDF is available here.
Abstract
Research using human embryonic stem cells raises an array of complex ethical issues, including, but by no means limited to, the moral status of developing human life. Unfortunately much of the public discussion fails to take into account this complexity. Advocacy for liberal and conservative positio...
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PMID: 20579255
PDF is available here.
PDF is available here.
Abstract
We present here an overview of the challenges that have been surmounted and the ones that will have to be solved in order to situate Spain as a reference country in regenerative medicine worldwide....
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PMID: 20058198
PDF is available here.
PDF is available here.
Monash bioethics review (28)4 2009
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Monash bioethics review (28)4 2009
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Monash bioethics review (28)4 2009
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We have injected murine wild type (WT) ESCs into a variety of mutant murine blastocysts, which are predisposed to develop a human-like disease, such as muscular dystrophy or the embryonic lethal "thin myocardial syndrome". In this review, we summarize data indicating that partial incorporation of ES...
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PMID: 19705303
PDF is available here.
PDF is available here.
Abstract
We have injected murine wild type (WT) ESCs into a variety of mutant murine blastocysts, which are predisposed to develop a human-like disease, such as muscular dystrophy or the embryonic lethal "thin myocardial syndrome". In this review, we summarize data indicating that partial incorporation of ES...
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PMID: 19705303
PDF is available here.
PDF is available here.
Abstract
We have injected murine wild type (WT) ESCs into a variety of mutant murine blastocysts, which are predisposed to develop a human-like disease, such as muscular dystrophy or the embryonic lethal "thin myocardial syndrome". In this review, we summarize data indicating that partial incorporation of ES...
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PMID: 19705303
PDF is available here.
PDF is available here.
Abstract
We present here an overview of the challenges that have been surmounted and the ones that will have to be solved in order to situate Spain as a reference country in regenerative medicine worldwide....
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PMID: 20058198
PDF is available here.
PDF is available here.
Abstract
We present here an overview of the challenges that have been surmounted and the ones that will have to be solved in order to situate Spain as a reference country in regenerative medicine worldwide....
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PMID: 20058198
PDF is available here.
PDF is available here.
Abstract
The executive order and issuance of federal guidelines for human embryonic stem cell research are positive developments and will produce long-term benefits by creating a new registry for hESC lines. But there may be short-term costs caused by regulatory uncertainty, procedural delay,...
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PMID: 20058195
PDF is available here.
PDF is available here.
Abstract
The executive order and issuance of federal guidelines for human embryonic stem cell research are positive developments and will produce long-term benefits by creating a new registry for hESC lines. But there may be short-term costs caused by regulatory uncertainty, procedural delay,...
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PMID: 20058195
PDF is available here.
PDF is available here.
Abstract
The executive order and issuance of federal guidelines for human embryonic stem cell research are positive developments and will produce long-term benefits by creating a new registry for hESC lines. But there may be short-term costs caused by regulatory uncertainty, procedural delay,...
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PMID: 20058195
PDF is available here.
PDF is available here.
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We summarize the recently developed methodologies used to generate iPS cells, including those that minimize their genetic manipulation, and discuss several important complicating features of iPS cells that may compromise their future use for therapies in regenerative medicine....
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PMID: 19761400
PDF is available here.
PDF is available here.
Abstract
It has been argued that bioethicists too often tend to represent the interests of scientists and not of the broader polity. Indeed, bioethicists seem predisposed to discard the voices and viewpoints of all but the cognoscenti. Focusing particularly on human pluripotent stem cell research, this comme...
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PMID: 19421896
PDF is available here.
PDF is available here.
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Many assumed that the Obama administration would usher in a sea change from the previous administration by expanding NIH support for human embryonic stem cell (hESC) research and reducing the patchwork of state and federal regulations that currently governs it. This article examines the extent to wh...
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PMID: 19886525
PDF is available here.
PDF is available here.
Human Fertility (12)2 2009
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In 2004, the Italian parliament comprehensively regulated medically assisted reproduction. Law 40/2004 has outlawed several techniques and tightly compressed the freedom of research in the area of human reproduction and regenerative medicine. This article analyses the post-2004 political, bioethical...
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PMID: 19802958
PDF is available here.
PDF is available here.
Abstract
The trend observed represents freedom of research to promote knowledge as a public good, emphasized by the expectation of therapeutic potentiality of embryonic stem cell research to treat and cure diseases without any medical care....
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PMID: 19377751
PDF is available here.
PDF is available here.
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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Chemistry & Biology (16)5 2009
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