Abstract
Efforts for drug free sport include developing a better understanding of the behavioural determinants that underline doping with an increased interest in developing anti-doping prevention and intervention programmes. Empirical testing of both is dominated by self-report questionnaires, which is the m...
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PMID: 21244663
PDF is available here.
Author(s) unavailable
Abstract
Characteristic of West Nile fever (WNF) virus strains circulating in southern Russia.
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PMID: 21598612
PDF is available here.
Abstract
The results of a meta-analysis about the efficacy of psychological treatment for children who have suffered physical maltreatment and neglect by their parents or tutors are presented. Sixteen studies that met our selection criteria were included, providing 22 treated groups and 8 control groups. The...
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PMID: 21044489
PDF is available here.
Abstract
To summarize the design and methodology of a large-scale trial in southern China, the Zhongshan Angle Closure Prevention (ZAP) trial. This trial will determine if laser iridotomy (LI) is superior to no treatment for managing Chinese people who are Primary Angle Closure Suspects (PACS). In this trial...
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PMID: 20868259
PDF is available here.
Abstract
We conducted a systematic review of case-crossover (CCO) designs used to study the relationship between air pollution and morbidity and mortality, from the standpoint of methodology and application.
A search was made of the MEDLINE and EMBASE databases.Reports were classified as methodologic or appl...
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PMID: 20356818
PDF is available here.
Abstract
We performed a comprehensive search (from January 1980-December 2008, all age groups, any language, any population) of 9 databases: MEDLINE, EMBASE, CINAHL, Current Contents, PsycINFO, ACP Journal Club, CCTR, CDSR, and DARE. Controlled vocabulary supplemented with keywords was used to define the con...
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PMID: 20458101
PDF is available here.
Shinichi Kuriyama,
Naoki Nakaya,
Kaori Ohmori-Matsuda,
Taichi Shimazu,
Nobutaka Kikuchi,
Masako Kakizaki,
Toshimasa Sone,
Fumi Sato,
Masato Nagai,
Yumi Sugawara,
Yasutake Tomata,
Munira Akhter,
Mizuka Higashiguchi,
Naru Fukuchi,
Hideko Takahashi,
Atsushi Hozawa and
Ichiro Tsuji
Abstract
The Ohsaki Cohort 2006 Study is a novel population-based prospective cohort study that focuses on psychosocial factors and long-term care insurance certification....
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PMID: 20410670
PDF is available here.
Abstract
NNTs for olanzapine vs. risperidone and for olanzapine vs. quetiapine were similar across the observational studies and similar to those of CATIE. The NNTs for olanzapine vs. oral typical antipsychotics were similar across the observational studies but demonstrated a somewhat stronger effect size th...
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PMID: 20446228
PDF is available here.
Abstract
Increased frequency of data collection may reduce incidence estimates....
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PMID: 20220522
PDF is available here.
Abstract
Important frequency measures in cohort studies are incidence and mortality. Important effect measures such as the relative risk (RR), hazard ratio (HR), standardized incidence ratio (SIR), standardized mortality ratio (SMR), and odds ratio (OR) can also be calculated. In case-control or cross-sectio...
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PMID: 20386677
PDF is available here.
Abstract
Rare Diseases Epidemiology is a novel action field still largely unexplored. However, Rare Diseases is a topic of growing interest at world level. The aims of this chapter are to revise useful epidemiological tools and define areas where epidemiology can help improve the rare disease knowledge, and...
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PMID: 20824437
PDF is available here.
Abstract
Over the past five years, the release of cohort studies assessing the link between cannabis and psychosis has increased attention on this relationship. Existing reviews generally conclude that these cohort studies show cannabis has a causal relationship to psychosis, or at least that one cannot be e...
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PMID: 19783132
PDF is available here.
Abstract
Epidemiologic research involves the study of a complex set of host, environmental and causative agent factors as they interact to impact health and diseases in any population. The most advanced of these efforts have focused on micro (cellular) or macro (human) population level studies but lacked the...
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PMID: 20521416
PDF is available here.
Abstract
Partial r(2) ranged from 0.028 to 0.099. PPP generally alleviated imbalances in nonpsychiatry-related patient characteristics, and the overall imbalance was reduced by an average of 36% (+/-40%) over the two cohorts. CONCLUSION: In our study setting, most of the 25 formulations of the PPP IV were st...
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PMID: 19345561
PDF is available here.
Abstract
The gold standard of study design for treatment evaluation is widely acknowledged to be the randomized controlled trial (RCT). Trials allow for the estimation of causal effect by randomly assigning participants either to an intervention or comparison group; through the assumption of "exchangeability...
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PMID: 19356901
PDF is available here.
Abstract
Two recent studies analyzed thyroid cancer incidence in Belarus and Ukraine during the period from 1990 to 2001, for the birth cohort 1968 to 1985, and the related (131)I exposure associated with the Chernobyl accident in 1986. Contradictory age-at-exposure and time-since-exposure effect modificatio...
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PMID: 19772472
PDF is available here.
Abstract
The methodical quality of health services research studies is often subject to criticism. Common standards in the field of health services research have been lacking so far. Hence, the German Network Health Services Research [Deutsches Netzwerk Versorgungsforschung e.V. (DNVF e.V.)] decided to contr...
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PMID: 19697288
PDF is available here.
Abstract
The purpose of this study was to determine the impact of 2 different calculation methods for total leisure-time physical activity energy expenditure (LTPAEE) and LTPAEE from different intensity activities on the classification of level of physical activity in the population. Nationally representativ...
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PMID: 19767802
PDF is available here.
Abstract
Acquired immunity is an important factor in the epidemiology of campylobacteriosis in the developing world, apparently limiting symptomatic infection to children of less than two years. However, also in developed countries the highest incidence is observed in children under five years and the majorit...
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PMID: 19514906
PDF is available here.
Abstract
We will argue that in both current trials and meta-analyses, interventions and comparisons are not sufficiently well described; that complex programs have been excessively oversimplified; and that potentially salient differences in programs, populations, and settings are not incorporated into analys...
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PMID: 19628113
PDF is available here.
Abstract
We consider an integrated epidemiologic design using a population-based estimating equation approach that can be considered a further extension of the multilevel design. Although the integrated design uses the same individual-level and group-level data as the multilevel design, it includes aggregate...
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PMID: 19436212
PDF is available here.
Abstract
We define overadjustment bias as control for an intermediate variable (or a descending proxy for an intermediate variable) on a causal path from exposure to outcome. We define unnecessary adjustment as control for a variable that does not affect bias of the causal relation between exposure and outco...
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PMID: 19525685
PDF is available here.
Jesper H JH Pedersen,
Haseem H Ashraf,
Asger A Dirksen,
Karen K Bach,
Hanne H Hansen,
Phillip P Toennesen,
Hanne H Thorsen,
John J Brodersen,
Birgit Guldhammer BG Skov,
Martin M Døssing,
Jann J Mortensen,
Klaus K Richter,
Paul P Clementsen and
Niels N Seersholm
Abstract
Screening may facilitate minimal invasive treatment and can be performed with a relatively low rate of false-positive screen results compared with previous studies on lung cancer screening....
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PMID: 19357536
PDF is available here.
Abstract
In these simulations, incidence-density sampling with matching on attained age plus age at death introduced bias. This is because sampled controls were younger at first exposure, with higher cumulative exposure compared with controls selected by matching on attained age alone. Incidence-density samp...
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PMID: 19289956
PDF is available here.
Abstract
We examined both of these arguments and found them to be incorrect. We describe an appropriate empirical evaluation method to explore the performance of nested case-control study designs and analysis methods from an existing cohort. This empirical evaluation approach relies on simulating case-contro...
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PMID: 19289963
PDF is available here.
Abstract
We presented the rationale and calculation procedures of the propensity score matching (PSM), and its application in the designing stage of an epidemiological study. Based on existing observational data, PSM can be used to select one or more comparable controls for each subject in 'treatment' group...
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PMID: 19799153
PDF is available here.
Abstract
Scientific evidence should guide clinical care, but special methodological challenges influence interpretation of the medical literature pertaining to older adults. Missing data, ranging from lack of individual items in questionnaires to complete loss to follow-up, affect the quality of the evidence...
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PMID: 19220562
PDF is available here.
Abstract
The discriminant analysis yielded weights for the nine causality criteria. These weights were used to combine the nine criteria into one overall assessment of the probability that an association is causal. The criteria strength, consistency of the association and experimental evidence were the three...
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PMID: 18834711
PDF is available here.
Abstract
We discuss different design proposals for a phase II trial in which three active treatment doses and a placebo control are to be compared in terms of a single-ordered categorical endpoint. The sample size requirements for one-stage and two-stage designs are derived, based on an approach similar to t...
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PMID: 19061203
PDF is available here.
Abstract
We may keep collecting time-to-event data until study termination from those patients who discontinued the treatment and conduct an intent-to-treat analysis by including them in the original treatment groups. We derive formulas necessary to calculate the asymptotic power of the log-rank test under t...
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PMID: 19152230
PDF is available here.
Abstract
In situations with missing data, statistical analyses are usually limited to subjects with complete data. However, such estimates may be biased. The method of 'filling in' missing data is called imputation. This article aimed to present a multiple imputation method. From a data set of 470 surgical p...
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PMID: 19219234
PDF is available here.
Abstract
Incidence of VHA in 20-40 age group represented 70.8%, and 33.5% in 20-25 age group. Diagnosis index was unfavourable with influence for interval of hospitalization over 21 days in 9.7% of cases. The VHA characteristic medium clinical form was kept in 80.1% of total patients. ASAT and ALAT levels we...
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PMID: 20191903
PDF is available here.
Abstract
We must ensure that observed effect is not caused by factors other than these under investigation. These last, called confounders of analyzed variables, influencing simultaneously both analyzed quantities may generate spurious non existing in reality relationships or change direction of these really...
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PMID: 20301954
PDF is available here.
Abstract
I accompanied a cultural communication network in the production of epidemiological data, which used an ethnographic approach to studies of science. Inserted in the daily activities of an epidemiological research group, I registered some aspects of the scientific production process, such as the stra...
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PMID: 19824334
PDF is available here.