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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Controlled Clinical Trials as Topic (1):
Recent article
Controlled Clinical Trials as Topic
Psychological Medicine (40)1 2010
Abstract
CBT is no better than non-specific control interventions in the treatment of schizophrenia and does not reduce relapse rates. It is effective in major depression but the size of the effect is small in treatment studies. On present evidence CBT is not an effective treatment strategy for prevention of...
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PMID: 19476688
PDF is available here.
PDF is available here.
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Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege / Deutsche Gesellschaft fur Sozialpadiatrie und Deutsche Gesellschaft fur Kinderheilkunde (29)1 2010
Abstract
Abstract
We found an association between participation in the German diabetes DMP and reduced mortality. This reduced mortality cannot be attributed directly to the DMP. However, further research should evaluate whether a primary care-based DMP contributes to increased life expectancy in patients with diabet...
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PMID: 20148605
PDF is available here.
PDF is available here.
Abstract
Presently, no clinical recommendations can be made with regard to RLX and its effects on breast density. To determine the effect of RLX on breast density, larger studies need to be conducted in postmenopausal women with high breast density at baseline who are at high risk for BC, with a standardized...
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PMID: 20032799
PDF is available here.
PDF is available here.
Abstract
After 8 weeks, the trial-based analysis showed that treatment with olmesartan versus losartan, valsartan, and irbesartan resulted in a significantly larger decrease in BP (11.5 vs 8.2, 7.9 and 9.9 mmHg [p < 0.05], respectively) and consequently more complications averted. Cost effectiveness for olme...
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PMID: 20104934
PDF is available here.
PDF is available here.
Abstract
The antipsychotic treatment of schizophrenia is still marked by poor compliance, and drug discontinuation; the development of more effective and safer drugs still remains a challenge. Sertindole is a second-generation antipsychotic with high affinity for dopamine D(2), serotonin 5-HT(2A), 5-HT(2C),...
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PMID: 20856845
PDF is available here.
PDF is available here.
Zhonghua Yixue Zazhi (89)46 2009
Abstract
There were 2121 patients (1062 cases in treatment group and 1059 cases in control group) from 16 controlled clinical trials were enrolled. Response rate increased (46.3% vs 40.6%, OR = 1.28, P = 0.006) and 1-year survival rate increased (44.6% vs 39.3%, OR = 1.25, P = 0.04) in treatment group than t...
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PMID: 20193364
PDF is available here.
PDF is available here.
Abstract
Wiener Medizinische Wochenschrift (159)23-24 2009
Abstract
We conducted a limited systematic literature research in order to find out if there is evidence for the use of any systemic pharmacological substance for the symptomatic relief of dyspnoea in chronic heart failure patients. Three randomised controlled trials with opioids could be identified. The qua...
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PMID: 20151346
PDF is available here.
PDF is available here.
Abstract
Medicina Intensiva (33)9 2009
Abstract
Diabetes Research and Clinical Practice (86 Suppl 1) 2009
Abstract
More intensive diabetes control prevents microangiopathy in patients with both type 1 diabetes and type 2 diabetes. The data related to prevention of macrovascular disease in patients with type 2 diabetes are controversial. The data confirming benefit of the HbA(1c) levels below 6.5% came almost exc...
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PMID: 20115934
PDF is available here.
PDF is available here.
Abstract
ABLC is effective and well-tolerated in the treatment of systemic fungal infections and remains a valuable therapeutic option in a variety of immunocompromised patients due to its broad antifungal spectrum and rarity of resistance. LIMITATIONS: Data from randomised controlled trials of lipid-based a...
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PMID: 19849324
PDF is available here.
PDF is available here.
Therapeutische Umschau (66)11 2009
Abstract
Vasopressin plays a physiological role in regulation of blood pressure, fluid volume, and serum osmolality. In heart failure inadequate release of vasopressin may result in excess fluid retention and hyponatremia. Vasopressin receptor antagonists are a new class of orally active drugs targeted to in...
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PMID: 19885790
PDF is available here.
PDF is available here.
Abstract
I conditions, with anxiety disorders being the most common co-morbidity. Therefore, the objective of this article is to review clinical and epidemiological studies that have investigated the association between bipolar disorder and anxiety. Available data on the efficacy of treatments for bipolar di...
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PMID: 19845416
PDF is available here.
PDF is available here.
Dental update (36)8 2009
Abstract
Evidence-based dentistry has grown in recent years. The oceans of journals and research papers can be difficult to navigate. Gauging the quality of such publications and, more importantly, their clinical relevance may be challenging.This narrative review explores the nature and relevance of dental r...
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PMID: 19927459
PDF is available here.
PDF is available here.
Southern Medical Journal (102)10 Suppl 2009
Abstract
This article describes the critical studies that examine the cardioprotective and renoprotective efficacy of ARBs and identifies the populations and doses at which these agents are most effective. DISCUSSION: In the clinical setting, ARBs may be a valuable alternative to ACEI therapy. Because of the...
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PMID: 19834426
PDF is available here.
PDF is available here.
Abstract
Clinical trials indicate that levocetirizine is safe and effective for the treatment of allergic rhinitis and chronic idiopathic urticaria. The compound shows a rapid onset of action, high bioavailability and affinity for the H1 receptor. Moreover, this molecule demonstrates many anti-inflammatory e...
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PMID: 19663743
PDF is available here.
PDF is available here.
Abstract
Further controlled intervention trials with larger sample sizes are required in order to confirm and extend these findings. We argue that the clinical staging model provides a framework for the rationale and design of such studies, with simpler, safer, and more benign interventions being better cand...
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PMID: 19573499
PDF is available here.
PDF is available here.
Abstract
I disorder. Placebo-controlled studies have been conducted with lithium, anticonvulsants, and atypical antipsychotics, but more research is needed, especially in areas other than acute manic and mixed episodes. Additional studies are needed to determine the safest and most effective agents for treat...
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PMID: 19818240
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (151)37 2009
Abstract
Medicina Clínica (133)8 2009
Abstract
Abstract
We found 38 randomized controlled trials (RCTs) and 35 non-RCTs, and extracted 68 quotes from the abstracts and 139 from the main text. A significant interaction was found between study design and direction of results for the abstract quotes (P=0.022). The ratings for non-RCTs were higher when the r...
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PMID: 19211223
PDF is available here.
PDF is available here.
Psychiatria Danubina (21)3 2009
Abstract
Abstract