Quique Q Bassat,
Sónia S Machevo,
Cristina C O'Callaghan-Gordo,
Betuel B Sigaúque,
Luís L Morais,
Núria N Díez-Padrisa,
Josep L JL Ribó,
Inácio I Mandomando,
Tacilta T Nhampossa,
Edgar E Ayala,
Sergi S Sanz,
Martin M Weber,
Anna A Roca and
Pedro L PL Alonso
Abstract
We investigated ways to increase diagnostic accuracy in patients hospitalized with clinical symptoms compatible with malaria and severe pneumonia, in an area with high a prevalence of infection with human immunodeficiency virus. A total of 646 children admitted at the Manhiça District Hospital in M...
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PMID: 21976562
PDF is available here.
Abstract
Abstract. A cohort study was designed to assess the impact of mass distribution of azithromycin (MDA) for trachoma control on incidence over six months of pediatric diarrhea in eight communities in rural Tanzania. A single dose of azithromycin was offered to all residents in four communities, where t...
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PMID: 21976574
PDF is available here.
Abstract
Type 2 diabetes mellitus (T2DM) and its attendant complications, such as diabetic nephropathy (DN), impose a significant societal and economic burden. The investigation of discovering potential biomarkers for T2DM and DN will facilitate the prediction and prevention of diabetes. Phos...
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PMID: 21872008
PDF is available here.
Abstract
The authors assessed changes in the health status of US 1991 Gulf War-era veterans from a 1995 baseline survey to a 2005 follow-up survey, using repeated measurement data from 5,469 deployed Gulf War veterans and 3,353 nondeployed Gulf War-era veterans who participated in both survey...
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PMID: 21795757
PDF is available here.
Abstract
To investigate the prevalence, distribution, and prognostic role of BRAF mutations in a large cohort of white patients with non-small-cell lung cancer (NSCLC).
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PMID: 21825258
PDF is available here.
Abstract
This study assessed outcomes of individuals with advanced cancer who required admission to an intensive care unit (ICU) after referral for an early clinical trial because they did not respond to conventional therapy.
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PMID: 21844494
PDF is available here.
Abstract
Patients with head and neck cancer (HNC) are at high risk of death resulting from noncancer causes and second malignancies (ie, competing mortality). Variation in competing mortality risk complicates individual treatment choices and design and interpretation of clinical studies.
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PMID: 21844503
PDF is available here.
Abstract
The purpose of this study was to examine knee valgus in drop landings during three different footwear conditions and to examine the ground reaction forces exhibited during the drop landing in the three different footwear conditions.
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PMID: 21977709
PDF is available here.
Abstract
Coronary artery disease (CAD) is a common and multifactorial arterial disease that is mainly caused by atherosclerosis. Macrophages, lymphocytes and neutrophils have been implicated in atherosclerotic plaque development. Autophagy, a highly conserved cellular process for the removal...
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PMID: 21812771
PDF is available here.
Abstract
We propose an estimator for models in which an endogenous dichotomous treatment affects a count outcome in the presence of either sample selection or endogenous participation using maximum simulated likelihood. We allow for the treatment to have an effect on the participation or the sample selection...
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PMID: 21830253
PDF is available here.
Abstract
To investigate associations between serum bisphenol A (BPA) concentrations and follicular response to exogenous ovary stimulation.
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PMID: 21813122
PDF is available here.
Abstract
We propose a practical risk stratification system highly predictive of long-term survival outcomes after OLT using DCD grafts. Application of this predictive index for transplant candidates receiving DCD liver grafts would improve patients' outcomes and optimize use of scarce resources....
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PMID: 21930997
PDF is available here.
Abstract
Human papillomavirus (HPV) is the cause of almost all cases of cervical cancer. The current UK government immunisation program includes free routine HPV vaccination of girls aged 12-13, with a catch-up vaccination program for 13-18-year-old girls. The aim of this study was to identify correlates of i...
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PMID: 21851772
PDF is available here.
Abstract
The purpose of this study was to examine (a) the effects of three curricular activities on students'situational motivation (intrinsic motivation [IM], identified regulation [IR], external regulation, and amotivation [AM]) and physical activity (PA) levels, and (b) the predictive stre...
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PMID: 21957712
PDF is available here.
Abstract
Little is known about trends in the timing of first nephrology consultation and associated outcomes among older patients initiating dialysis.
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PMID: 21824952
PDF is available here.
Abstract
We examined urban/rural patterns in receipt of treatment for non-mall cell lung cancer (NSCLC) (ie, surgery, chemotherapy, radiation therapy) among black and white Medicare beneficiaries in Alabama.
After linking Alabama State Cancer Registry data with state Medicare data, we identif...
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PMID: 22046848
PDF is available here.
Abstract
Tobacco use is the leading cause of preventable mortality and morbidity in the United States. Patients advised to quit use of tobacco products by their health care providers are more likely to quit, yet it has been documented that patients are not receiving this advice. The aim of th...
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PMID: 22046843
PDF is available here.
Abstract
We enrolled 469 participants aged 40 to 74 years, including 28% African Americans, 5% Latinos, 25% with Medicaid, and 10% without any form of insurance. Participants in the intervention group showed statistically significantly higher rates of cancer screening; rates were 41% vs 16.8% for mammography...
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PMID: 22046855
PDF is available here.
Abstract
Recognition of trauma-induced coagulopathy by conventional coagulation testing (CCT) is limited by their slow results, incomplete characterization, and their poor predictive nature. Rapid thrombelastography (r-TEG) delivers a more comprehensive assessment of the coagulation system bu...
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PMID: 21825945
PDF is available here.
Abstract
The purpose of this study was to compare the prognostic role of various computed tomography (CT) signs of right ventricular (RV) dysfunction, including 3-dimensional ventricular volume measurements, to predict adverse outcomes in patients with acute pulmonary embolism (PE).
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PMID: 21835376
PDF is available here.
Abstract
Necrotizing fasciitis (NF), a life-threatening soft tissue infection, requires early diagnosis, prompt and repeated surgical intervention, and broad-spectrum antibiotic therapy. The aim of this study was to identify the independent predictors of mortality among patients with NF in Taiwan.
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PMID: 21825948
PDF is available here.
Abstract
To investigate the relationship of obstructive sleep apnea (OSA) with positional dependency and to identify its clinical implication in an Asian population.
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PMID: 21844412
PDF is available here.
Abstract
This study is the first nationwide population survey to explore the association between speed of eating and degree of obesity. The objective was to cross-sectionally examine the relationship between self-reported speed of eating and body mass index (BMI; calculated as kg/m(2)) in a n...
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PMID: 21802566
PDF is available here.
Abstract
There is limited information on which characteristics are associated with water intake among adolescents. This cross-sectional study examined the association between demographic, dietary, and behavioral factors and low water intake as the outcome measure. Analyses were based on the 2...
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PMID: 21802569
PDF is available here.
Abstract
PURPOSE OR BACKGROUND: Interleukin (IL)-10 is an immunoregulatory cytokine that is produced by a variety of cell types, such as macrophages and activated monocytes. IL-10 possesses numerous anti-inflammatory, anti-thrombotic and anti-atherosclerotic properties. Furthermore, patients with acute corona...
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PMID: 21787901
PDF is available here.
Philip P Haaf,
Cathrin C Balmelli,
Tobias T Reichlin,
Raphael R Twerenbold,
Miriam M Reiter,
Julia J Meissner,
Nora N Schaub,
Claudia C Stelzig,
Michael M Freese,
Patricia P Paniz,
Christophe C Meune,
Beatrice B Drexler,
Heike H Freidank,
Katrin K Winkler,
Willibald W Hochholzer and
Christian C Mueller
Abstract
We hypothesized that NT-proBNP might be useful in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction....
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PMID: 21787902
PDF is available here.
Abstract
The purposes of this study were to analyse and compare aspects of validity (concurrent and discriminant) of the two widely used indirect utility instruments, the EuroQol-5D (EQ-5D) and the Short Form-6D (SF-6D) in a representative cohort of patients with rheumatoid arthritis (RA).
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PMID: 21813061
PDF is available here.
Abstract
There were 1,317 DCIs during the study period. These were observed in a cohort of 923 patients, out of a total of 17,288 patients, representing 5,339 DCIs per 100,000 patients, or 5.3% of all patients over a 1-year period. Of the 923 exposed patients, 745 (80.7%) were exposed to 1 DCI event, 92 (10%...
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PMID: 21781650
PDF is available here.
Abstract
Based on the dataset evaluated in this study, we demonstrated that human plasma concentration-time profiles and pharmacokinetic parameters could be predicted with the Dedrick and C(ss)-MRT approaches and that if correction factors were implemented, the predictions improved significantly. With the re...
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PMID: 21740074
PDF is available here.
Abstract
the orthostatic HR response and, to a lesser extent, SBP recoverability, appear impaired in frailty. Orthostatic haemodynamics may be useful markers of frailty....
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PMID: 21749997
PDF is available here.
Abstract
A history of trauma is associated with poor mental and physical health, but the specific impact of posttraumatic stress disorder (PTSD) symptoms on physical health using objective indicators of health status has rarely been evaluated in elderly civilians. This study investigates the long-term consequ...
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PMID: 21824455
PDF is available here.
Abstract
I or II, with a mean peak Vo(2) of 18 ml/min/kg. According to the age-adjusted reference values, hormonal deficiencies were present in 29% for total testosterone, 39% for estimated free testosterone, 34% for insulin-like growth factor-1, and 61% for dehydroepiandrosterone sulfate. Dehydroepiandroste...
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PMID: 21752346
PDF is available here.
Abstract
Prosthetic mesh used for incisional hernia repair (IHR) reduces hernia recurrence. Mesh infection results in significant morbidity and challenges for subsequent abdominal wall reconstruction. The risk factors that lead to mesh explantation are not well known.
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PMID: 21741517
PDF is available here.
Abstract
We examine the Joint Theater Trauma Registry (JTTR) for infections and potential risk factors, such as transfusions, among Iraq and Afghanistan trauma patients....
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PMID: 21795880
PDF is available here.
Abstract
To evaluate treatment outcomes in patients with carbapenem-resistant Acinetobacter baumannii (CRAB) nosocomial infections treated with antimicrobial agent either alone or in combination.
Clinical data were retrospectively evaluated in patients with CRAB nosocomial inf...
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PMID: 21774295
PDF is available here.
Abstract
We analyzed associations between the level of podoplanin expression and various clinicopathologic parameters, including response to radiochemotherapy, clinical and histological N-status. Furthermore we evaluated the effects of these parameters on overall survival and on locoregional control in univa...
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PMID: 21767977
PDF is available here.
Abstract
Fewer patients are undergoing reoperative coronary artery bypass grafting (CABG). We investigated the prevalence of redo vs primary CABG and previous percutaneous coronary intervention (PCI), changing trends in preoperative risk profiles, and independent predictors of operative death.
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PMID: 21718829
PDF is available here.
Abstract
Survival after heart transplant has improved and more attention is focused on developmental outcomes. We aimed to determine the survival, morbidity, and developmental outcomes of young children after heart transplant.
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PMID: 21545999
PDF is available here.
Abstract
Patients with impaired left ventricular ejection fraction (LVEF) and severe aortic stenosis have a higher perioperative risk for aortic valve replacement. Transapical aortic valve implantation (TA-AVI) allows for off-pump valve implantation, which might be beneficial in the subgroup of patients with...
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PMID: 21718826
PDF is available here.
Abstract
Advances in treatment of congenital heart disease (CHD) have resulted in most patients surviving to adulthood. Despite surgical "correction," the need for reoperation(s) persists, and there are few outcome data. This study examined early postoperative results to determine risk factors for cardiac inj...
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PMID: 21718837
PDF is available here.
Abstract
To study the prognosis and the factors affecting the prognosis in children with acute respiratory distress syndrome (ARDS).
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PMID: 21752318
PDF is available here.
Abstract
Blood transfusion during acute lymphoblastic leukemia (ALL) of childhood is scarcely documented. Children with ALL are immunosuppressed by both the disease and its therapy. Transfusion may contribute to the course of ALL through its transfusion-related immunomodulation (TRIM) effect....
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PMID: 21671359
PDF is available here.
Abstract
With the increasing emergence of multiresistant pathogens, better understanding of these infections is necessary. The aim of the present study was to evaluate the risk factors associated with isolating a multiresistant organism (MRO) from a positive blood culture in pediatric cancer...
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PMID: 21671364
PDF is available here.
Abstract
We retrospectively reviewed 71 inpatient episodes of ACS in patients with hemoglobin SC disease over a 20-year period. Continuous and categorical data from index cases were compared with that from 71 control cases of ACS in patients with hemoglobin SS disease.
Median length of hospit...
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PMID: 21671365
PDF is available here.
Abstract
To identify risk factors for 4-year incidence and progression of age-related macular degeneration (AMD) in adult Latinos.
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PMID: 21679916
PDF is available here.
Abstract
To investigate risk factors for primary open-angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) in the Thessaloniki Eye Study.
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PMID: 21664597
PDF is available here.
Abstract
To investigate the association between certain socio-demographic characteristics and dental health status of 5- to 12-year-old children attending public kindergarten and primary schools in Piraeus, Greece.
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PMID: 21692785
PDF is available here.
Abstract
We demonstrate that a blood culture positive for B. pseudomallei taken at the end of the first and/or second week after hospitalization for melioidosis is a strong prognostic factor for death (adjusted odds ratio = 4.2, 95% confidence interval = 2.1-8.7, P...
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PMID: 21633019
PDF is available here.
Abstract
We examined the joint association of mortality with metabolic syndrome and serum alkaline phosphatase levels in the US general population....
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PMID: 21605734
PDF is available here.
Maria Rosa MR Conte,
Sergio S Bongioanni,
Amedeo A Chiribiri,
Stefano S Leuzzi,
Elisabetta E Lardone,
Paolo P Di Donna,
Alfredo A Pizzuti,
Stefania S Luceri,
Federico F Cesarani,
Barbara B Mabritto,
Giuseppe Biondi GB Zoccai,
Rodolfo R Bonamini and
Fiorenzo F Gaita
Abstract
Cardiac magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) can identify areas of myocardial fibrosis in vivo in patients with hypertrophic cardiomyopathy (HCM). The aim of this study was to examine the association between clinical-morphological variables, risk factor for sudden d...
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PMID: 21641353
PDF is available here.
Abstract
Aortic stenosis (AS) is the commonest native valve lesion, affecting 43% of all patients with valvular heart disease. The optimal treatment of severe AS in cancer patients is unknown. The purpose of this study was to assess the impact of aortic valve replacement (AVR) on survival of cancer patients w...
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PMID: 21641359
PDF is available here.
Abstract
We investigated whether baseline levels of hsTnT were associated with response to CRT and with severe cardiovascular events after long-term follow-up....
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PMID: 21641347
PDF is available here.
Abstract
We investigated their relationship with death, heart failure (HF) readmission, and reinfarction combined (termed major adverse cardiac events [MACE]) and, separately, in unselected patients using Global Registry of Acute Coronary Events Risk Scoring (GRACE-RS) and n terminal pro B type natriuretic p...
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PMID: 21641364
PDF is available here.
Óscar Ó Prada-Delgado,
Rodrigo R Estévez-Loureiro,
Ramón R Calviño-Santos,
Eduardo E Barge-Caballero,
Jorge J Salgado-Fernández,
Pablo P Piñón-Esteban,
Jose Manuel JM Vázquez-Rodríguez,
Guillermo G Aldama-López,
Xacobe X Flores-Ríos,
María Rita MR Soler-Martín,
Nicolás N Vázquez-González and
Alfonso A Castro-Beiras
Abstract
The use of vascular closure devices (VCDs) for the reduction of access site complications following percutaneous coronary intervention (PCI) remains controversial. Patients undergoing primary PCI for acute ST-segment elevation myocardial infarction (STEMI) are at high risk of femoral artery complicat...
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PMID: 21641370
PDF is available here.