Abstract
We hypothesized that, with hypertension, localized iNOS inhibition would restore vasodilation in response to NO-dependent stimuli, and iNOS expression would be increased and phosphorylated vasodilator-stimulated phosphoprotein would be decreased. For, in vivo protocols, 4 intradermal microdialysis f...
|
PMID: 21931069
PDF is available here.
Abstract
We propose an alternative approach based on omnibus tests of equality of means and variances and in subject-by-subject analyses (where applicable), and we show that these tests have adequate Type I error rates and power. The approach is illustrated with a re-analysis of published data from a signal...
|
PMID: 22059346
PDF is available here.
Abstract
Our results indicated that in the absence of visual and auditory cues, subjects reported that the tactile system was useful in the execution of C2 and C3 maneuvers. Specifically, the presence of tactile cues had a significant impact on the accuracy, duration, and perceived workload. In addition, tac...
|
PMID: 21961399
PDF is available here.
Abstract
All soldiers in the U.S. Army are required to complete mask confidence training with o-chlorobenzylidene malononitrile (CS). To instill confidence in the protective capability of the military protective mask, CS is thermally dispersed in a room where soldiers wearing military protect...
|
PMID: 22010329
PDF is available here.
Abstract
Biliary atresia (BA) is an idiopathic progressive inflammation and fibrosclerosis of the extra and intrahepatic bile ducts.
|
PMID: 21922857
PDF is available here.
Abstract
We aimed to estimate cyanogens detoxifying enzyme rhodanese, thiocyanate and sulfur containing amino acids in cassava consumer as well as cassava non-consumer TCP patients and healthy controls and compare the same....
|
PMID: 21922874
PDF is available here.
Abstract
We measured 25OHD concentrations in a multi-ethnic group of pregnant women living in Vancouver (49 degrees N) and explored the determinants of 25OHD....
|
PMID: 21913590
PDF is available here.
Abstract
The purpose of this study was to evaluate and analyze statistical shapes of the outer mandible contour of Caucasian and Chinese people, offering data for the production of preformed mandible reconstruction plates.
|
PMID: 21094050
PDF is available here.
Abstract
This study examined the repeatability of and agreements between central corneal thickness measurements obtained by four different non-contact pachymetry devices.
Seventy-eight eyes of 39 subjects were included. Central corneal thickness of each eye was measured by Vis...
|
PMID: 21899245
PDF is available here.
Abstract
We studied 363 patients who underwent laparoscopic anterior resection with intracorporeal rectal transection and double-stapling technique (DST) anastomosis for rectal cancer between July 2005 and February 2010. Twenty-two independent clinical variables were examined by univariate and multivariate a...
|
PMID: 21871980
PDF is available here.
Abstract
Hilar cholangiocarcinoma (HC) is invariably fatal without surgical intervention. The primary aim of the current study was to report overall survival and recurrence-free survival outcomes after surgical resection of HC.
Between December 1992 and December 2009, 85 patie...
|
PMID: 21871986
PDF is available here.
Abstract
Chronic obstructive pulmonary disease (COPD) is often associated with changes of the structure and the function of the right ventricle (RV). Therefore, the assessment of right ventricular function and myocardial mass (MM) is clinically important for the evaluation of the severity of COPD, which may p...
|
PMID: 21852436
PDF is available here.
Abstract
Many sport and exercise activities require powerful movements of the upper body. Despite their importance, there is a paucity of research examining stretch-shortening cycle (SSC) activities occurring in the upper limbs. The purpose of this study was to examine the effect of fatigue on throwing perfor...
|
PMID: 21936288
PDF is available here.
Abstract
Tkachev on uneven bars is a release and re-grasp skill performed using variations of preparatory longswing techniques; the reasons why different techniques are chosen remains unclear. This study examined kinematic and key release parameters specific to three distinct techniques with the aim of unders...
|
PMID: 21936286
PDF is available here.
Abstract
The secure and efficient affixation of EEG electrodes is an integral part of performing neurotelemetry; however there are currently no recommendations for the ideal method of affixing the electrodes that has evidence-based support. The purpose of this study was to find and determine...
|
PMID: 21988035
PDF is available here.
Abstract
Our data demonstrate the contribution of GDNF to DA neuron development and may also elucidate pathogenetic mechanisms in Parkinson disease and contribute to the development of novel therapies for the disorder....
|
PMID: 21865882
PDF is available here.
Abstract
We performed biochemical characterization and quantification of TDP-43 in homogenates from parietal neocortex of subjects with aclinical diagnosis of no cognitive impairment (NCI, n = 12), mild cognitive impairment (MCI, n = 12), or AD (n = 12). Immunoblots revealed increased detergent-insoluble TDP...
|
PMID: 21865887
PDF is available here.
Abstract
The purpose of this study was to examine the role of physical education in shaping physical activity patterns. Seventy-one Hispanic and African American elementary students participated in the study. Students attended one 30- and one 60-min physical education class weekly. Pedometer...
|
PMID: 21957710
PDF is available here.
Abstract
We examined the measurement properties offall-related psychological instruments with a sample of 133 older adults (M age = 74.4 years, SD = 9.4). Measures included the Comprehensive Falls Risk Screening Instrument, Falls-efficacy Scale-International (FES-I), Activities-specific Balance Confidence (A...
|
PMID: 21957713
PDF is available here.
Abstract
We investigated the effects of self-controlled practice on learning multiple motor skills. Thirty participants were randomly assigned to self-control or yoked conditions. Participants learned a three-keystroke pattern with three different relative time structures. Those in the self-control group cho...
|
PMID: 21957703
PDF is available here.
Abstract
The purpose of this study was to observe the effects of a submaximal isometric training program on estimation capacity at 25, 50, and 75% of maximal contraction in isometric action and at two angular velocities. The second purpose was to study the variability of isometric action. To...
|
PMID: 21957704
PDF is available here.
Abstract
Using differential item functioning (DIF) analyses, this study examined whether there were any DF items in the National Health and Nutrition Examination Survey (NHANES) physical activity (PA) questionnaire. A subset of adult data from the 2003-04 NHANES study (n = 3,083) was used. PA...
|
PMID: 21957696
PDF is available here.
Abstract
Our data suggest that the mTOR signaling pathway is involved in SPC-modulated melanin synthesis....
|
PMID: 21838918
PDF is available here.
Abstract
Although oligoarticular juvenile idiopathic arthritis (oJIA) is considered to carry the best prognosis among the JIA subtypes, many children evolve to a chronic course. A few studies have identified clinical risk factors for disease extension, and recent studies have evaluated synovial fluid markers....
|
PMID: 21813070
PDF is available here.
Abstract
This study sought to determine whether a formalized teaching intervention could reduce the interobserver variability (IOV) in visual estimation of left ventricular ejection fraction (LVEF) within a group of sonographers and physicians with a spectrum of experience.
|
PMID: 21835373
PDF is available here.
Abstract
We sought to assess the prognostic value and risk classification improvement using contemporary single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI) to predict all-cause mortality.
|
PMID: 21835380
PDF is available here.
Abstract
The objective of this study was to assess dental students' attitudes toward underserved populations across their four years of dental school. Students at the Herman Ostrow School of Dentistry of the University of Southern California were invited to take part in the study. Participating students compl...
|
PMID: 21828295
PDF is available here.
Abstract
The purposes of this quasi-experimental, one-group crossover study were to determine the effect of questioning during dental hygiene lectures on low-level and high-level learning and to evaluate student perceptions of questioning. Twenty-three dental hygiene students participated in two control lectu...
|
PMID: 21828301
PDF is available here.
Abstract
The purpose of this study was to investigate the level of psychological stress as well as the perceived sources of stress among undergraduate dental students at the University of Jordan. The top perceived stressors were compared with those of a previous study that examined the perceived sources of st...
|
PMID: 21828305
PDF is available here.
Abstract
Dentists and dental students can be exposed to the human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) during routine work. The aims of this study were to assess a group of dental students' knowledge about HIV, HBV, and HCV infections; assess their attitudes and r...
|
PMID: 21828306
PDF is available here.
Abstract
We assessed whether demographic, body composition, and ambulatory activity measures were predictive of arterial elasticity within each group. Fifty-one American Indians and 66 Caucasians between the ages of 8 and 30 years were assessed on large artery elasticity index, small artery elasticity index,...
|
PMID: 21828174
PDF is available here.
Abstract
We combined viral genetic strategies with genetic mouse models to investigate the contribution of NMDARs in the dopamine system to appetitive Pavlovian conditioning. NMDAR signaling in dopamine neurons was not required for Pavlovian conditioning; however, NMDARs in D(1) dopamine receptor (D(1)R)-exp...
|
PMID: 21813695
PDF is available here.
Abstract
Slow eating may be associated with reduced energy intake. A device that counts bites can provide bite-rate feedback to the user. The purpose of this study was to explore the bite counter's utility for slowing bite-rate and reducing energy intake. The study was a within-participants d...
|
PMID: 21802572
PDF is available here.
Abstract
We have used 2-DE coupled with MS to identify proteins differentially expressed in the livers of juvenile gilthead sea bream (Sparus aurata) grown under fish-farm conditions and fed with a 100 mg/kg MA-enriched diet (MA(100)). After the comparison of the protein profiles from MA(100) fed fish and...
|
PMID: 21751345
PDF is available here.
Abstract
Hepatitis C virus (HCV), a major cause of liver disease throughout the world, is difficult to treat with interferon (IFN) (and various formulations and combinations thereof) being the only approved molecule available. It has been investigated recently that proinflammatory chemokine i...
|
PMID: 21554996
PDF is available here.
Abstract
Changes in gene expression of beta1- and beta2-adrenoceptors (beta1 - and beta2-AR) in right and left atria and ventricles after fluoxetine treatment in stress-induced depression of adult rat males were studied. Elevated beta1-AR mRNA levels in the left atria and significantly higher...
|
PMID: 21901985
PDF is available here.
Abstract
Selected muscles in the kinetic chain may help explain the body's ability to avert injury during unexpected perturbation.
|
PMID: 21828381
PDF is available here.
Abstract
Recent evidence has revealed deficiencies in the ability to divide attention after concussion.
|
PMID: 21828382
PDF is available here.
Abstract
The latency of the peroneus longus in response to an inversion perturbation is a key component in the prevention of lateral ankle sprains. In addition, the dominant ankle is sprained more frequently than the nondominant ankle, but the cause of this has not been examined.
|
PMID: 21828384
PDF is available here.
Abstract
Soft-tissue injuries are commonly treated with ice or menthol gels. Few studies have compared the effects of these treatments on blood flow and muscle strength.
|
PMID: 21828387
PDF is available here.
Abstract
We performed mixed model regressions to examine group differences in trajectory and volume. The COS group had smaller bilateral anterior lobes and anterior and total vermis volumes than controls. The COS group diverged from controls over time in total, left, right, and bilateral posterior inferior c...
|
PMID: 21803550
PDF is available here.
Abstract
We examine the effect of endotoxin-induced inflammation on Ox neuron biology and LMA in rats. Our results demonstrate a vital role for diminished Ox signaling in mediating inflammation-induced lethargy. This work defines a specific population of inflammation-sensitive, arousal-associated Ox neurons...
|
PMID: 21813697
PDF is available here.
Abstract
quality of life was reduced in both behavioural groups compared with participants without either condition. Disability was greater in the group with apathy. Variation in disability score (56%, P < 0.001) was explained by greater levels of apathy, depression, motor impairment and longer disease dur...
|
PMID: 21788252
PDF is available here.
Abstract
The N2 and P3 components of the event-related potential (ERP) are putative markers of inhibition in the Go/NoGo task. If this is the case, they should be unaffected by stimulus presentation modality. Theoretical researchers have suggested that the effect is smaller or absent with auditory stimuli, wh...
|
PMID: 21764566
PDF is available here.
Abstract
We investigated the role of the neurokinin-1, dopamine D1 and D2 receptors on the METH-induced cytogenesis. To that end, male mice were given a single injection (30mg/kg, ip) or a binge of METH (10mg/kg, 4× at two-hour intervals, ip). BrdU (100mg/kg, ip) was given 36h after the last injection of ME...
|
PMID: 21652034
PDF is available here.
Abstract
Currently, imaging assessment of patients who undergo transcatheter aortic valve implantation is based mainly on echocardiography and angiography, both limited to provide a 3-dimensional evaluation of the prosthesis within the native valve. This study involved 34 patients who underwe...
|
PMID: 21741025
PDF is available here.
Abstract
We explored the independent and combined associations of physical fitness, measured using the seated at rest heart rate (RHR), and the metabolic syndrome (MS), with CVD risk, as described by an elevated pulse wave velocity (PWV) in older Chinese. Data from 1,996 participants were drawn from the Guan...
|
PMID: 21784386
PDF is available here.
Abstract
The cytochrome P450 (CYP) 2C19*2 loss-of-function allele has been associated with impaired clopidogrel response and worse prognosis in clopidogrel-treated patients. The benefit of tailored therapy according to platelet function test results remains unclear, and the potential effect o...
|
PMID: 21803320
PDF is available here.
Abstract
We tested whether circulating miRNAs in the plasma of critically ill patients with acute kidney injury (AKI) at the inception of renal replacement therapy are deregulated and may predict survival.
We profiled miRNAs using RNA isolated from the plasma of patients with AKI and healthy...
|
PMID: 21700819
PDF is available here.
Abstract
Summary Background and objectives Serum creatinine (sCr) increments currently used to define acute kidney injury (AKI) do not take into consideration the baseline level of kidney function. The objective of this study was to establish whether baseline estimated GFR (eGFR) provides add...
|
PMID: 21700828
PDF is available here.
Abstract
We aimed to identify factors associated with endogenous EPO levels and investigate their relation to all-cause mortality. Design, setting, participants, & measurements Between 2004 and 2005, 215 patients with type 2 diabetes were enrolled. Exclusion criteria included stage renal disease ESRD and any...
|
PMID: 21734083
PDF is available here.
Abstract
We measured total body protein (TBP) by in vivo neutron activation, expressed as nitrogen index (NI), and lean body mass (LBM) and total body fat (TBF) by dual-energy x-ray absorptiometry. Visceral and subcutaneous fat areas (SFAs) were determined from computed tomography. Comparisons were made betw...
|
PMID: 21734086
PDF is available here.
Abstract
We combined methods of computer simulation and experiments based on circular dichroism (CD) to investigate the structural characteristics of CaM that influence its target recognition in crowded cell-like conditions. We developed a unique multiscale solution of charges computed from quantum chemistry...
|
PMID: 21829336
PDF is available here.
Abstract
We assessed the impact of a clopidogrel LD (≥300 mg) compared to a conventional dose (<300 mg) on bleeding, need for blood transfusion, and 30-day and 12-month survivals in 791 elderly patients (≥75 years old, mean age 81 ± 4 years, 48% women, 35% with ST-segment elevation MI) included in this...
|
PMID: 21726837
PDF is available here.
Abstract
Previous study of the ear ossicles in Primates has demonstrated that they vary on both functional and phylogenetic bases. Such studies have generally employed two-dimensional linear measurements rather than three-dimensional data. The availability of Ultra- high-resolution X-ray computed tomography (...
|
PMID: 21732321
PDF is available here.
Sterling C Johnson,
Asenath La Rue,
Bruce P Hermann,
Guofan Xu,
Rebecca L Koscik,
Erin M Jonaitis,
Barbara B Bendlin,
Kirk J Hogan,
Allen D Roses,
Ann M Saunders,
Michael W Lutz,
Sanjay Asthana,
Robert C Green and
Mark A Sager
Abstract
We tested the hypothesis that brain and cognitive changes suggestive of presymptomatic LOAD may be associated with this TOMM40 polymorphism.
Among healthy APOE ε3 homozygous adults (N = 117; mean age, 55 years), we compared those who were homozygous for VL/VL (n = 35) TOMM40 poly-T...
|
PMID: 21784354
PDF is available here.
Abstract
Aim for this study was to investigate the effect of long-acting beta2-adrenoceptor agonist formoterol on airway goblet cell hyperplasia and protein Muc5ac expression in asthmatic mice.
|
PMID: 21780541
PDF is available here.
Abstract
Fewer patients are undergoing reoperative coronary artery bypass grafting (CABG). We investigated the prevalence of redo vs primary CABG and previous percutaneous coronary intervention (PCI), changing trends in preoperative risk profiles, and independent predictors of operative death.
|
PMID: 21718829
PDF is available here.