Abstract
Dementia is associated with increased rates and often poorer outcomes of hospitalization, including worsening cognitive status. New evidence is needed to determine whether some admissions of persons with dementia might be potentially preventable.
To determine whether...
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PMID: 22235087
PDF is available here.
Eric A Engels,
Ruth M Pfeiffer,
Joseph F Fraumeni,
Bertram L Kasiske,
Ajay K Israni,
Jon J Snyder,
Robert A Wolfe,
Nathan P Goodrich,
A Rana Bayakly,
Christina A Clarke,
Glenn Copeland,
Jack L Finch,
Mary Lou Fleissner,
Marc T Goodman,
Amy Kahn,
Lori Koch,
Charles F Lynch,
Margaret M Madeleine,
Karen Pawlish,
Chandrika Rao,
Melanie A Williams,
David Castenson,
Michael Curry,
Ruth Parsons,
Gregory Fant and
Monica Lin
Abstract
Solid organ transplant recipients have elevated cancer risk due to immunosuppression and oncogenic viral infections. Because most prior research has concerned kidney recipients, large studies that include recipients of differing organs can inform cancer etiology.
To d...
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PMID: 22045767
PDF is available here.
Abstract
To evaluate the efficacy and toxicity of CHG regimen (low-dose cytarabine, homoharringtonine with G-CSF priming) as an induction chemotherapy for elderly patients with high-risk MDS or acute myeloid leukemia transformed from MDS (MDS-AML).
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PMID: 21845438
PDF is available here.
Abstract
We sought to assess whether the alteration of the peri-implantation maternal environment resulting from ovarian stimulation may contribute to increased risk of low birth weight in IVF births....
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PMID: 21934450
PDF is available here.
Abstract
Various subgroups of breast tumours have been identified during the last 10 years according to the risk of local relapse. Prognostic factors for local relapse are age, surgical margins, tumour size, Her2 expression and hormonal receptors status. For tumours with a high risk of local relapse, an incre...
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PMID: 21820932
PDF is available here.
Abstract
States that adopt a basic GDL law can expect a decrease of 8 to 14 percent in the proportion of 16- and 17-year-old drivers involved in fatal crashes (relative to 21- to 25-year-old drivers), depending upon their other existing laws that affect novice drivers, such as those used in these analyses. T...
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PMID: 21972851
PDF is available here.
Abstract
Wasting is common in hemodialysis patients and often is accompanied by cardiovascular disease and inflammation. The cardiovascular risk profile meaningfully changes with the progression of kidney disease, and little is known about the impact of wasting on specific clinical outcomes. This study examin...
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PMID: 21820222
PDF is available here.
Abstract
Patients undergoing elective percutaneous coronary intervention (PCI) are generally observed overnight in the hospital. The association between same-day discharge of older patients and death or readmission is unclear.
To evaluate the prevalence and outcomes of same-da...
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PMID: 21972308
PDF is available here.
Abstract
We enrolled 3493 infants receiving antibiotics for suspected or proven serious infection and randomly assigned them to receive two infusions of either polyvalent IgG immune globulin (at a dose of 500 mg per kilogram of body weight) or matching placebo 48 hours apart. The primary outcome was death or...
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PMID: 21962214
PDF is available here.
Abstract
For women in the WHI CaD who were not taking personal calcium or vitamin D supplements at randomization, CaD decreased the risk of total, breast, and colorectal cancers and did not change the risk of fractures or total mortality. The nonskeletal effects of CaD may be more important than the skeletal...
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PMID: 21880848
PDF is available here.
Abstract
We aimed to estimate cyanogens detoxifying enzyme rhodanese, thiocyanate and sulfur containing amino acids in cassava consumer as well as cassava non-consumer TCP patients and healthy controls and compare the same....
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PMID: 21922874
PDF is available here.
Abstract
We hypothesized that a long interdialytic interval is associated with adverse events in patients receiving hemodialysis.
We studied 32,065 participants in the End-Stage Renal Disease Clinical Performance Measures Project, a nationally representative sample of U.S. patients receiving...
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PMID: 21992122
PDF is available here.
Abstract
We have experience exciting developments regarding the approval of new treatment options but few patients are reaching sustained remission and refractory patients continue to be a problem. Thus, it is critical to understand how clinicians can decrease the risk of refractoriness by close monitoring d...
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PMID: 21570496
PDF is available here.
Abstract
Since 1996, 16 states have legalized marijuana use for medical purposes. The current study provides a scientific assessment of the association of medical marijuana laws (MML) and adolescent marijuana use using national data.
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PMID: 21820632
PDF is available here.
Abstract
Despite progress, many hypertensive patients remain uncontrolled. Defining characteristics of uncontrolled hypertensives may facilitate efforts to improve blood pressure control.
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PMID: 21824920
PDF is available here.
Abstract
Few data are available on long-term outcomes among adolescents and young adults with persistent asymptomatic isolated microscopic hematuria.
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PMID: 21846854
PDF is available here.
Abstract
Previous studies indicate that the population attributable risk (PAR) of bladder cancer for tobacco smoking is 50% to 65% in men and 20% to 30% in women and that current cigarette smoking triples bladder cancer risk relative to never smoking. During the last 30 years, incidence rates have remained st...
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PMID: 21846855
PDF is available here.
Abstract
Sleep-disordered breathing (characterized by recurrent arousals from sleep and intermittent hypoxemia) is common among older adults. Cross-sectional studies have linked sleep-disordered breathing to poor cognition; however, it remains unclear whether sleep-disordered breathing precedes cognitive impa...
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PMID: 21828324
PDF is available here.
Abstract
To compare induction of labor and expectant management by gestational week with regard to the need for cesarean section (CS) in labor.
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PMID: 21542808
PDF is available here.
Abstract
The effect of comorbidities on postoperative outcomes in patients with inflammatory bowel disease (IBD) has not been explored adequately. We evaluated the prevalence of comorbidities and their effect on postoperative outcomes after an IBD-related operation.
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PMID: 21844437
PDF is available here.
Abstract
The angiotensin I-converting enzyme (ACE) is involved in cell proliferation, angiogenesis, inflammation, and tissue remodeling, all of which could play a role in carcinogenesis. The DD genotype of ACE I/D polymorphism with a higher ACE level than either ID or II genotypes was reporte...
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PMID: 21928698
PDF is available here.
Abstract
Acne vulgaris (AV) is a chronic inflammatory skin disease that affects millions of people. Psychologic disorders such as depression, anxiety, and body dysmorphic disorder are common in patients with AV and the reported prevalence of suicidal ideation and suicide completion in acne patients also is re...
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PMID: 21916276
PDF is available here.
Abstract
The purpose of the study was to assess the cardiovascular risk of impaired fasting glucose (IFG).
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PMID: 21718910
PDF is available here.
Philip A PA Roberts,
Younes Y Boudjemline,
John P JP Cheatham,
Andreas A Eicken,
Peter P Ewert,
Doff B DB McElhinney,
Sharon L SL Hill,
Felix F Berger,
Danyal D Khan,
Dietmar D Schranz,
John J Hess,
Michael D MD Ezekowitz,
David D Celermajer and
Evan E Zahn
Abstract
This study sought to describe the first human series of percutaneous tricuspid valve replacements in patients with congenital or acquired tricuspid valve (TV) disease.
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PMID: 21718905
PDF is available here.
Ibhar I Al Mheid,
Riyaz R Patel,
Jonathan J Murrow,
Alanna A Morris,
Ayaz A Rahman,
Lucy L Fike,
Nino N Kavtaradze,
Irina I Uphoff,
Craig C Hooper,
Vin V Tangpricha,
R Wayne RW Alexander,
Kenneth K Brigham and
Arshed A AA Quyyumi
Abstract
The primary objective of this study was to elucidate mechanisms underlying the link between vitamin D status and cardiovascular disease by exploring the relationship between 25-hydroxyvitamin D (25-OH D), an established marker of vitamin D status, and vascular function in healthy adults.
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PMID: 21718915
PDF is available here.
Abstract
The aim of the present study was to investigate whether right coronary artery chronic total occlusion (CTO) carries prognostic implications in patients undergoing drug-eluting stent-supported percutaneous coronary intervention (PCI) for unprotected left main disease (ULMD).
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PMID: 21718907
PDF is available here.
Paul S Chan,
Manesh R Patel,
Lloyd W Klein,
Ronald J Krone,
Gregory J Dehmer,
Kevin Kennedy,
Brahmajee K Nallamothu,
W Douglas Weaver,
Frederick A Masoudi,
John S Rumsfeld,
Ralph G Brindis and
John A Spertus
Abstract
Despite the widespread use of percutaneous coronary intervention (PCI), the appropriateness of these procedures in contemporary practice is unknown.
To assess the appropriateness of PCI in the United States.
Multicenter, prospective study of patients w...
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PMID: 21730241
PDF is available here.
Abstract
We created a simple prognostic tool to estimate this combined outcome. Methods and Results We identified factors associated with 6-month mortality or persistently unfavorable QoL, defined by Kansas City Cardiomyopathy Questionnaire (KCCQ) scores <45 at 1 and 24 weeks after hospital discharge, among...
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PMID: 21693723
PDF is available here.
Abstract
Existing evidence of the survival associated with bariatric surgery is based on cohort studies of predominantly younger women with a low inherent obesity-related mortality risk. The association of survival and bariatric surgery for older men is less clear.
To determin...
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PMID: 21666276
PDF is available here.
Abstract
To examine possible associations between chronic inflammatory arthritides and pregnancy outcomes with separate analyses of first and subsequent births before and after diagnosis.
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PMID: 21630243
PDF is available here.
Abstract
Hepatitis B virus (HBV) transmission via blood and other body fluids from infected individuals to healthy people has been largely demonstrated. However, in the current literature, there is little information available on the potential role of cerumen in HBV transmission. Cerumen and blood were collec...
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PMID: 21715280
PDF is available here.
Yen-Li YL Lo,
Chin-Fu CF Hsiao,
Yuh-Shan YS Jou,
Gee-Chen GC Chang,
Ying-Huang YH Tsai,
Wu-Chou WC Su,
Kuan-Yu KY Chen,
Yuh-Min YM Chen,
Ming-Shyan MS Huang,
Wan-Shan WS Hsieh,
Chien-Jen CJ Chen and
Chao A CA Hsiung
Abstract
We conducted a case-control study to investigate the associations between the risk of lung cancer and genetic polymorphisms in the MLH1 and MSH2 genes. The SNP genotypes were determined in 730 lung cancer patients and 730 healthy controls that were frequency matched for the age, gender, and smoking...
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PMID: 21093954
PDF is available here.
Abstract
We have recently shown that allergy may also increase the expression level of influenza virus receptors. This suggests that airway allergy and viral infection may have a reciprocal interaction. The effect of allergy on the risk and outcome of viral infection needs to be further confirmed in clinical...
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PMID: 21980825
PDF is available here.
Georg G Pfeiler,
Robert R Königsberg,
Christian C Fesl,
Brigitte B Mlineritsch,
Herbert H Stoeger,
Christian F CF Singer,
Sabine S Pöstlberger,
Guenther G GG Steger,
Michael M Seifert,
Peter P Dubsky,
Susanne S Taucher,
Hellmut H Samonigg,
Vesna V Bjelic-Radisic,
Richard R Greil,
Christian C Marth and
Michael M Gnant
Abstract
We investigated the influence of body mass index (BMI) on the efficacy of adjuvant endocrine therapy in premenopausal patients in a retrospective analysis of the Austrian Breast and Colorectal Cancer Study Group (ABCSG) 12 trial....
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PMID: 21555684
PDF is available here.
Abstract
We have generated and characterized nonhuman primate iPS cells with the goal of evaluating iPS cell transplantation in a clinically relevant large animal model. We developed stable Phoenix-RD114-based packaging cell lines that produce OCT4, SOX2, c-MYC, and KLF4 (OSCK) expressing gammaretroviral vec...
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PMID: 21058905
PDF is available here.
Abstract
We reviewed our CRC epidemiology, international screening age-guidelines, and screening tests for the elderly persons and presented our long-term results of colonoscopy and semi-quantitated immunochemical fecal occult blood tests (I-FOBTs) in individuals that are 75 years or more....
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PMID: 21448071
PDF is available here.
Abstract
We avoided providing general anesthesia for a biopsy and a central venous catheter placement. In all cases, chest X-rays on admission showed mediastinal mass ratio (MMR) greater than 44% and thoracic computed tomographic scans demonstrated cross sectional area (CSA) of the trachea 60% less than expe...
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PMID: 21626866
PDF is available here.
Abstract
Although obesity is becoming a major public health problem, data are limited on the relationship between body mass index (BMI) and survival in Taiwanese populations. Therefore, the aim of this study was to evaluate the long-term effects of obesity on the risk of death from any cause and from specific...
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PMID: 21621149
PDF is available here.