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Abstract
We conducted a systematic literature review to identify studies published between January 1, 1985, and March 15, 2011. Summary estimates of sensitivity and specificity were obtained by using a summary receiver-operating characteristic (SROC) curve. Study quality was assessed by using the QUADAS surv...
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PMID: 21917673
PDF is available here.
PDF is available here.
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Abstract
Ventilator-associated pneumonia (VAP) is the most common hospital-acquired, life-threatening infection. Poor outcome and health-care costs of nosocomial pneumonia remain a global burden. Currently, physicians rely on their experience to discriminate patients with good and poor outcome. However, stand...
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PMID: 21835904
PDF is available here.
PDF is available here.
Abstract
We assessed in-hospital prognostic value of admission plasma B-type natriuretic peptide (BNP) levels in patients undergoing primary percutaneous coronary intervention (p-PCI) for acute ST-elevation myocardial infarction (STEMI).
In a retrospective design, we evaluated 992 patients (8...
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PMID: 21983763
PDF is available here.
PDF is available here.
Abstract
Different risk-prediction models have been developed, but none is generally accepted in selecting patients for esophagectomy. This study evaluated 5 most frequently used risk-prediction models, including the American Society of Anesthesiologists, Portsmouth-modified Physiological and...
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PMID: 21871985
PDF is available here.
PDF is available here.
Abstract
Computed tomography (CT) is becoming increasingly popular as a non-invasive method for visualizing the coronary arteries but patient radiation doses are still an issue. Postprocessing filters such as 2D adaptive non-linear filters might help to reduce the dose without loss of image quality.
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PMID: 21852437
PDF is available here.
PDF is available here.
Abstract
Asthma may be frequently associated with allergic rhinitis. Bronchial obstruction is a characteristic of asthma and spirometry is a cardinal step in asthma diagnosis. However, spirometry is rarely suitable in medical office. Visual Analogue Scales (VAS) is frequently used in common p...
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PMID: 21858258
PDF is available here.
PDF is available here.
Abstract
Abstract
We sought to further delineate the relevance of the major individual components of early volume resuscitation to onset of MOD after severe blunt traumatic injury....
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PMID: 21825930
PDF is available here.
PDF is available here.
Acta Cardiologica (66)4 2011
Abstract
Aortic valve calcifications (AVC) as seen on conventional chest films or on CT are associated with aortic valve stenosis (AVS). The absence of AVC on chest films does not exclude high grade AVS. The aim of this study was to analyse if there is a threshold for the detection of AVC from conventional ch...
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PMID: 21894808
PDF is available here.
PDF is available here.
Abstract
PURPOSE OR BACKGROUND: Interleukin (IL)-10 is an immunoregulatory cytokine that is produced by a variety of cell types, such as macrophages and activated monocytes. IL-10 possesses numerous anti-inflammatory, anti-thrombotic and anti-atherosclerotic properties. Furthermore, patients with acute corona...
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PMID: 21787901
PDF is available here.
PDF is available here.
Abstract
We hypothesized that NT-proBNP might be useful in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction....
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PMID: 21787902
PDF is available here.
PDF is available here.
Abstract
We conclude that FASn may aid in the diagnosis of prostatic adenocarcinoma, at least to supplement AMACR as another positive marker of carcinoma and potentially increase diagnostic accuracy....
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PMID: 21757596
PDF is available here.
PDF is available here.
Abstract
We used data from the PREVEND (Prevention of Renal and Vascular ENdstage Disease) study, a prospective population-based cohort study with a median follow-up of 6.4 years. Participants with two or three consecutive estimated GFR (eGFR) measurements during follow-up were included. Participants within...
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PMID: 21734089
PDF is available here.
PDF is available here.
Abstract
We propose a novel Bayesian integration method, deemed nonparametric Bayes ensemble learning (NBEL), to lower the misclassification rate (both false positives and negatives) through automatically up-weighting data sources that are most informative, while down-weighting less informative and biased so...
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PMID: 21829334
PDF is available here.
PDF is available here.
Abstract
We aimed to analyze the diagnostic and prognostic potential of a newly developed high-sensitive troponin T assay and compared these results with those of a contemporary troponin T assay in 2 distinct patient cohorts, one including patients with evident ACS and the other one including patients with g...
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PMID: 21742093
PDF is available here.
PDF is available here.
Abstract
Cirrhosis is associated with poor outcomes in the trauma setting. We aimed to evaluate the utility of Model for End-Stage Liver Disease (MELD) in assessing additional mortality risk in trauma patients with cirrhosis.
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PMID: 21818010
PDF is available here.
PDF is available here.
Abstract
Traumatic blunt cerebrovascular injury (BCVI) may portend catastrophic complications if untreated. Who should be screened for BCVI is controversial. The purpose of this study was to develop and validate a prediction score (pBCVI) to identify those at sufficient risk to warrant dedicated screening.
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PMID: 21818020
PDF is available here.
PDF is available here.
Abstract
To determine hepatitis C virus (HCV) seroprevalence and its genotypes, and to identify the factors associated with HCV infection.
This cross-sectional study, conducted in two prisons (one male and one female) in the State of Sergipe, Brazil, comprised 422 subjects. Al...
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PMID: 21799649
PDF is available here.
PDF is available here.
Abstract
Our study demonstrates the ability of this technique to confirm the presence of paternal alleles from ccff DNA in maternal plasma.
Copyright © 2011 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserve...
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PMID: 21704271
PDF is available here.
PDF is available here.
Abstract
To determine the minimal clinically important difference and the patient acceptable symptom state for visual acuity and visual function, 2 key visual outcomes for patients undergoing cataract extraction, as an aid for evaluating the outcome of cataract extraction.
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PMID: 21683328
PDF is available here.
PDF is available here.
Abstract
Echocardiographic measurements of left ventricular (LV) function, predominantly LV ejection fraction (LVEF), have been used to define risk in patients after myocardial infarction. However, the extent to which measures of LV structure and function provide incremental prognostic value over clinical var...
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PMID: 21641363
PDF is available here.
PDF is available here.
Abstract
Many descriptors of left ventricular (LV) remodeling have important prognostic implications in patients with chronic systolic heart failure (HF). We sought to assess the prognostic value of the combination of increased LV mass with a disproportion between wall thickness and internal diameter.
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PMID: 21641355
PDF is available here.
PDF is available here.
Abstract
We investigated their relationship with death, heart failure (HF) readmission, and reinfarction combined (termed major adverse cardiac events [MACE]) and, separately, in unselected patients using Global Registry of Acute Coronary Events Risk Scoring (GRACE-RS) and n terminal pro B type natriuretic p...
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PMID: 21641364
PDF is available here.
PDF is available here.
Abstract
We also investigated the following additional methods to improve CAD performance: 1) grouping 2-D detected features into a single 3-D object; 2) selecting features with a genetic algorithm (GA); and 3) limiting the number of allowed suspicious lesions to be cued in one examination. The results showe...
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PMID: 20693106
PDF is available here.
PDF is available here.
Abstract
We hypothesized that there would be no difference in outcome at Level I versus Level II trauma centers....
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PMID: 21817972
PDF is available here.
PDF is available here.
Abstract
We defined the diagnostic criteria and prognostic value for proteins tested. In GC patients, the serum concentrations of all the proteins tested were significantly higher than in healthy subjects. The IL-6, CEA and CA 19-9 levels correlated with nodal metastases, while CRP with tumor stage, gastric...
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PMID: 20938721
PDF is available here.
PDF is available here.
Abstract
Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea, often diagnosed empirically based on clinical response to cholestyramine. The radionuclide selenium-labelled homocholic acid-taurine whole body retention test is expensive, labour intensive and of limited availability.
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PMID: 21766092
PDF is available here.
PDF is available here.
Abstract
To compare the peripapillary retinal nerve fiber layer (RNFL) thickness of normal patients and those with various glaucoma diseases by time domain (Stratus) and spectral domain (Spectralis) optical coherence tomography (OCT).
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PMID: 21655041
PDF is available here.
PDF is available here.
Abstract
Limitations of particular tests, the advantages of larger test batteries to more broadly examine multiple auditory processes, the degree to which the present results can be generalized clinically to populations without known brain lesions, and other clinical considerations are discussed....
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PMID: 21864472
PDF is available here.
PDF is available here.
Abstract
I (normal group, n=69) and group II (with total bilirubin >85.5 μmol/L for 7 days after hepatectomy, n=17) based on the levels of total bilirubin after hepatectomy. Group II was further divided into two subgroups: recovered subgroup (n=14) and fatal subgroup (n=3). There were no significant differe...
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PMID: 21669569
PDF is available here.
PDF is available here.
Abstract
ProGRP has better sensitivity and high specificity as an auxiliary indicator for the diagnosis of small cell lung cancer....
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PMID: 21649553
PDF is available here.
PDF is available here.
Oral Oncology (47)7 2011
Abstract
We performed a meta-analysis to evaluate the role of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)FDG-PET/CT) in detecting distant metastases and second primary cancers in patients with head and neck cancer (HNC) at staging. Studies about (18)FDG-PET/CT for detectin...
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PMID: 21621450
PDF is available here.
PDF is available here.
Abstract
This study evaluates the prognostic significance of [18F]-fluoro-2-deoxyglucose positron emission tomography/computed tomography findings according to histological subtypes in patients with completely resected non-small cell lung cancer.
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PMID: 21613306
PDF is available here.
PDF is available here.
Abstract
We also compared clinical efficiency by determining whether flagged specimens showed abnormalities on a peripheral blood smear as defined by International Council for Standardization in Haematology criteria. The efficiency, sensitivity, and specificity of the DxH 800 were 77.0%, 87.1%, and 73.0%, re...
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PMID: 21571967
PDF is available here.
PDF is available here.
Psychiatry Research (187)1-2 2011
Abstract
We examined whether a leading instrument for the prediction of future violence in those with a mental disorder. The Historical, Clinical, Risk Management-20 (HCR-20) was equally effective across a wide range of mental health diagnoses. Records at the time of discharge from secure psychiatric services...
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PMID: 21095013
PDF is available here.
PDF is available here.
Abstract
The amount of alcohol consumption has a negative impact on short-term mortality among Mexicans with AH. The ABIC score is useful and comparable with MELD score for the prognostic stratification of these patients.Am J Gastroenterol advance online publication, 10 May 2011; doi:10.1038/ajg.2011.141....
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PMID: 21556041
PDF is available here.
PDF is available here.
Abstract
We suggest applying automated modelling to reduce the time required, in particular when examining different outcomes of large numbers of procedures and diseases in routinely collected administrative health data....
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PMID: 21556848
PDF is available here.
PDF is available here.
Abstract
Objective-To evaluate the diagnostic value of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations in Doberman Pinschers in various stages of dilated cardiomyopathy (DCM). Animals-328 Doberman Pinschers. Procedures-Staging of DCM was determined via analysis of results of physic...
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PMID: 21529216
PDF is available here.
PDF is available here.
Abstract
Choosing a device for a teleradiology service should involve additional factors, such as capture time, maintenance concerns, and training requirements....
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PMID: 21457011
PDF is available here.
PDF is available here.
Abstract
Zinc deficiency leads to susceptibility to infections and may affect pulmonary epithelial cell integrity. Low zinc levels have also been associated with a degree of organ failure and decreased survival in critically ill children. Accordingly, the purpose of the study was to assess serum zinc in adult...
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PMID: 21827444
PDF is available here.
PDF is available here.
Abstract
Abstract
We studied 2,472 consecutive patients initially hospitalized in our institution from April 2004 to December 2009. Risk scores were calculated for each patient using 4 risk score models, including the Seattle Heart Failure Model (SHFM), Acute Decompensated Heart Failure National Registry regression m...
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PMID: 21600539
PDF is available here.
PDF is available here.
Abstract
Single dose-volume metrics are of limited value for the prediction of radiation pneumonitis (RP) in day-to-day clinical practice. We investigated whether multiparametric models that incorporate clinical and physiologic factors might have improved accuracy.
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PMID: 21543165
PDF is available here.
PDF is available here.
Abstract
We performed a prospective case-control study in asymptomatic and symptomatic young children. PCR detection of 14 respiratory viruses was performed in nasal washes, and results were quantified in copies per milliliter. A total of 141 cases and 157 controls were included. In 72% of the cases and 28%...
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PMID: 21543571
PDF is available here.
PDF is available here.
Abstract
Patients with advanced non-small cell lung cancer (NSCLC) seem to have disparity in prognosis. Accurate prediction of prognosis could be useful in the future to predict individual risk and to develop more aggressive or alternative treatment strategies.
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PMID: 21508201
PDF is available here.
PDF is available here.
Abstract
Respiratory motion is known to deteriorate positron emission tomography (PET) images and may lead to potential diagnostic errors when a standardized uptake value (SUV) cut-off threshold is used to discriminate between benign and malignant lesions.
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PMID: 21511870
PDF is available here.
PDF is available here.
Clinical Cancer Research (17)8 2011
Abstract
To determine the differential gene expression between oral squamous cell carcinoma (OSCC) with and without metastasis to cervical lymph nodes and to assess prediction of nodal metastasis by using molecular features.
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PMID: 21300763
PDF is available here.
PDF is available here.
Abstract
To identify the clinicopathological risk factors correlated with residual tumor in hepatocellular carcinoma (HCC) patients after resection.
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PMID: 21528064
PDF is available here.
PDF is available here.
Klinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukrainy, Naukove tovarystvo khirurhiv Ukrainy ()4 2011
Abstract
Diagnostic significance of the test with procalcitonin (PCT) for estimation of the patients state severity in extended purulent peritonitis (EPP) and prognostication of hospital lethality were studied up. For the comparison making the state severity was estimated in the patients in accordance to SOFA...
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PMID: 21698931
PDF is available here.
PDF is available here.
Abstract
We evaluated the efficacy of detecting both anti-60kD and 52kD SS-A/Ro antibodies....
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PMID: 21626876
PDF is available here.
PDF is available here.
Abstract
In this study, clinical utility of various renal function markers (Cystatin C, Creatinine, beta2-microglobulin, Urea nitrogen) including serum Cystatin C was evaluated by the latex turbidimetric immunoassay based on the Chronic Kidney Disease (CKD) stage classification. Serum creatinine was most corr...
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PMID: 21626875
PDF is available here.
PDF is available here.
Abstract
The label-free technique of optofluidic intracavity spectroscopy (OFIS) uses light transmitted through a cellular body in a microfluidic optical resonator to distinguish different types of cells by their optical properties. The OFIS technique has differentiated canine hemangiosarcoma...
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PMID: 20483694
PDF is available here.
PDF is available here.
Abstract
Neutrophils are rapidly released into the circulation upon acute stress such as trauma or acute myocardial infarction (AMI). We hypothesized that neutrophil count might provide incremental value in the early diagnosis and risk stratification of AMI.
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PMID: 21507368
PDF is available here.
PDF is available here.
Abstract
This paper addresses depth discrimination of a water column target from bottom clutter discretes in wideband active sonar. To facilitate classification, the waveguide invariant property is used to derive multiple snapshots by uniformly sub-sampling the short-time Fourier transform (STFT) coefficients...
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PMID: 21476638
PDF is available here.
PDF is available here.
Abstract
Fourteen observational studies were included which evaluated PET, PET/CT, CT and/or MRI. Study results were available in 12 studies for PET, in 5 studies for CT, in 5 studies for PET/CT and in 1 study for MRI. AUCs for PET, PET/CT and CT were 0.94 (0.90-0.97), 0.94 (0.87-0.98) and 0.83 (0.72-0.90),...
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PMID: 21468765
PDF is available here.
PDF is available here.
Abstract
We conducted a series of large-scale proteomic discovery and validation studies using preclinical samples from the Women's Health Initiative Observational Study prospective cohort. Of the 503 proteins quantified in experiments conducted on samples from ER(+) breast cancer patients and matched contro...
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PMID: 21761335
PDF is available here.
PDF is available here.
Abstract
We examined the application of an iterative penalized maximum likelihood (PML) reconstruction method for improved detectability of microcalcifications (MCs) in digital breast tomosynthesis (DBT). Localized receiver operating characteristic (LROC) psychophysical studies with human observers and 2-D im...
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PMID: 21041158
PDF is available here.
PDF is available here.
Medical Physics (38)4 2011
Abstract
The authors presented a novel system for automated nodule detection in lung CT exams.
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PMID: 21626929
PDF is available here.
PDF is available here.
Medical Physics (38)4 2011
Abstract
Mammography is known to be one of the most difficult radiographic exams to interpret. Mammography has important limitations, including the superposition of normal tissue that can obscure a mass, chance alignment of normal tissue to mimic a true lesion and the inability to derive volumetric informatio...
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PMID: 21626930
PDF is available here.
PDF is available here.
Medical Physics (38)4 2011
Abstract
To improve the performance of a computer-aided detection (CAD) system for mass detection by using four-view information in screening mammography.
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PMID: 21626920
PDF is available here.
PDF is available here.