Abstract
Nucleoside reverse transcriptase inhibitors (NRTIs) are a key class of drugs for the treatment of HIV infection. NRTIs are intracellularly phosphorylated to their active triphosphate metabolites and compete with endogenous deoxynucleotides (dNTP) for substrate binding. It is therefor...
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PMID: 21862423
PDF is available here.
Abstract
We have recently reported that when cholesterol is oxidized with an ozone-like oxidant generated by activated mouse neutrophils, secosterol-A is generated which is then converted to secosterol-B by an aldol reaction. To investigate further pathophysiological roles of secosterols, we have developed a...
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PMID: 21871845
PDF is available here.
Abstract
A highly sensitive, selective and evaporation free SPE extraction, ESI-LC-MS/MS method has been developed for estimation of misoprostol free acid in human plasma using misoprostol acid-d(5) as an internal standard (IS). The analyte was separated using isocratic mobile phase on revers...
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PMID: 21872541
PDF is available here.
Abstract
Assessing energy requirements is a fundamental activity in clinical dietetics practice. A study was designed to determine whether published linear regression equations were accurate for predicting resting energy expenditure (REE) in fasted Hispanic children with obesity (aged 7 to 15...
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PMID: 21802568
PDF is available here.
Abstract
Proper diagnosis of Blastocystis hominis in not performed routinely in medical laboratories of developing countries; consequently clinical significance of this common intestinal protozoon is liable to remain unsettled. Food-handlers are more prone to get and transmit this feco-oral i...
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PMID: 21980782
PDF is available here.
Abstract
A total of 30 patients suffering from brucellosis were suspected based on history taking, clinical manifestations and positive serum tube agglutination test (at titer > or = 1/160). The followings were done for all cases; complete blood picture (differential leucocytic count) and liv...
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PMID: 21980786
PDF is available here.
Abstract
To develop a simple questionnaire to use for screening Thai people for knee osteoarthritis (OA).
Subjects' characteristics and data covering all known risk factors for OA were collected from a sample of villagers at Kanleurng Sub-District, Nakronpanom Province. Hip, k...
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PMID: 21863676
PDF is available here.
Abstract
Non-invasive tests play significant roles in the test-and-treat approach of Helicobacter pylori management. The detection of Helicobacter pylori antibodies in urine and serum is an easy and inexpensive way to diagnose this infection. In the present study, the authors developed an in-...
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PMID: 21863682
PDF is available here.
Abstract
We observed translate into differences associated with using traditional regressions to predict anthropometric variables in an aging population. Our data point to a need to consider age, obesity, and gender when utilizing anthropometric data sets and to develop regression models that accurately pred...
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PMID: 21844608
PDF is available here.
Abstract
The purpose of this study was to quantify the effect of soft tissue artifact during three-dimensional motion capture and assess the effectiveness of an optimization method to reduce this effect. Four subjects were captured performing upper-arm internal-external rotation with retro-reflective marker s...
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PMID: 21844615
PDF is available here.
Abstract
To investigate what sampling frequency is adequate for gait, the correlation of spatiotemporal parameters and the kinematic differences, between normal and CP spastic gait, for three sampling frequencies (100 Hz, 50 Hz, 25 Hz) were assessed. Spatiotemporal, angular, and linear displacement variables...
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PMID: 21844616
PDF is available here.
Abstract
To validate the accuracy of clinical ophthalmic information held on the West Australian blind register.
Community-based cross-sectional study.
Legally blind or severely vision-impaired people were selected randomly from the Association for the Blind of...
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PMID: 21819503
PDF is available here.
Abstract
The sensitivity of screening mammography is limited in the evaluation of dense breasts, with as few as 45% of cancers visible in extremely dense breasts. Supplementary imaging for improved sensitivity in women with dense breasts is necessary to overcome this limitation. Emerging technologies that adv...
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PMID: 21782119
PDF is available here.
Abstract
We discuss the current role of breast ultrasound and magnetic resonance imaging (MRI) in screening for breast cancer in the high-risk population. Breast ultrasound finds small cancers not seen on mammography particularly in women with dense breasts. Breast MRI has sensitivity significantly higher th...
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PMID: 21782116
PDF is available here.
Abstract
Screening has been successful in the early detection of some cancers, including cervical, colon, and breast. However, the success in mortality reduction by screening mammography has been limited in women with mammographically dense tissue. Magnetic resonance imaging has been used with success in the...
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PMID: 21782117
PDF is available here.
Abstract
Ductal carcinoma in situ (DCIS) is a preinvasive malignancy that currently accounts for over 20% of newly diagnosed breast cancers in the US. This article reviews how clinical magnetic resonance imaging methods are being implemented for the detection, diagnosis and characterization of DCIS. Research...
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PMID: 21782121
PDF is available here.
Abstract
We compared the morphologic features of sperm using Papanicolaou staining and an automated Sperm Quality Analyzer IIC-P (SQA-IIC-P; Medical Electronic Systems, Caesarea, Israel) and evaluated the role of factors affecting these features in semen samples from 201 infertile men. The sensitivity of the...
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PMID: 21757597
PDF is available here.
Abstract
We conclude that FASn may aid in the diagnosis of prostatic adenocarcinoma, at least to supplement AMACR as another positive marker of carcinoma and potentially increase diagnostic accuracy....
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PMID: 21757596
PDF is available here.
Abstract
In this paper, polychlorinated biphenyl (PCB), organochlorine pesticide (OCP) and pyrethroid pesticides in peach was investigated by comparing their residual level in peach juice, pulps and peels using dispersive liquid-liquid microextraction based on solidification of floating organ...
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PMID: 21703950
PDF is available here.
Abstract
In Hungary, mortality rates from colorectal cancer are dramatically high, therefore the reduction by population screening as a public health measure is considered as one of the priorities of National Public Health Program. In the beginning, a human-specific immunological test was applied in the "mode...
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PMID: 21788205
PDF is available here.
Abstract
Sixty-seven Holstein-Friesian cows, from 20 days postpartum, were recruited into the study and fitted with both a pedometer (SAE Afikim) and a Heatime neck collar (SCR Engineers) and allocated a heat mount detector (either scratchcard [Dairymac] or KaMaR [KaMaR]) or left with none, relying only on fa...
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PMID: 21730035
PDF is available here.
Abstract
Our study showed that RMI is very reliable in differentiation benign from malignant adnexal masses....
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PMID: 21899180
PDF is available here.
Abstract
Inaccuracies in the estimation of material properties and errors in the assignment of these properties into finite element models limit the reliability, accuracy, and precision of quantitative computed tomography (QCT)-based finite element analyses of the vertebra. In this work, a new mesh-independen...
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PMID: 21823740
PDF is available here.
Abstract
We compared the performance of Xpert MTB/RIF, MTBDRplus (Hain Lifescience), LightCycler Mycobacterium Detection (LCTB) (Roche), with acid fast bacilli (AFB) smear microscopy and liquid culture on a single sputum specimen....
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PMID: 21814495
PDF is available here.