Fu F Xiong,
Qiuying Q Huang,
Xiaoyun X Chen,
Yuqiu Y Zhou,
Xinhua X Zhang,
Ren R Cai,
Yajun Y Chen,
Jiansheng J Xie,
Shanwei S Feng,
Xiaofeng X Wei,
Qizhi Q Xiao,
Tianlang T Zhang,
Shiqiang S Luo,
Xuehuang X Yang,
Ying Y Hao,
Yanxia Y Qu,
Qingge Q Li and
Xiangmin X Xu
Abstract
The increasing number of disease-causing mutations demands a simple, direct, and cost-effective diagnostic genotyping technique capable of detecting multiple mutations. This study validated the efficacy of a novel melting curve analysis-based genotyping assay (MeltPro HBB assay) for...
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PMID: 21704277
PDF is available here.
Abstract
We describe the epidemiology and clinical characteristics of patients with MEH in a rural community in the Mayan area of Mexico with 53 cases and 54 controls. Clinical and epidemiological data were collected through a direct interview. Oral cell samples were collected with a cytobrush. Subjects coll...
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PMID: 21697033
PDF is available here.
Abstract
To describe immune ring (IR) formation as a manifestation of cytomegalovirus (CMV) endotheliitis.
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PMID: 21676373
PDF is available here.
Abstract
We report here a role for Cohibin at telomeres and show that functions of the complex at chromosome ends and rDNA maintain replicative life span. Cohibin binds LEM/SUN domain-containing nuclear envelope proteins and telomere-associated factors. Disruption of Cohibin or the envelope proteins abrogate...
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PMID: 21664583
PDF is available here.
Abstract
We show that activation of the nuclear receptor farnesoid X receptor (FXR) induces AKR1B7 expression in the liver and intestine, and reduces the levels of malondialdehyde (MDA), the end product of lipid peroxidation, in the intestine but not in the liver. To determine whether AKR1B7 regulates MDA le...
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PMID: 21642744
PDF is available here.
Abstract
Abstract Salmonella enterica subspecies enterica serotype 4,[5],12:i:- is an emerging serovar considered as a monophasic variant of Salmonella enterica serotype Typhimurium. The antigenic and genetic similarity between Salmonella 4,[5],12:i:- and Salmonella Typhimurium suggests that...
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PMID: 21247297
PDF is available here.
Abstract
Abstract Shiga toxin-producing Escherichia coli O157 is a leading cause of foodborne illness worldwide. To evaluate better methods to rapidly detect and genotype E. coli O157 strains, the present study evaluated the use of ampliPHOX, a novel colorimetric detection method based on pho...
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PMID: 21288130
PDF is available here.
Abstract
We report that a luciferase reporter containing the 3'-UTR of GR-α is significantly repressed in MM.1R cells when compared to MM.1S cells, suggesting that one or several microRNAs that are upregulated in MM.1R maybe in part responsible for the downregulation of the GR-α transcript. To examine post...
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PMID: 21761344
PDF is available here.
Abstract
We report paired strains of Leishmania parasites, one from the viscera and the other from skin lesions that were isolated from three patients with visceral leishmaniasis and disseminated cutaneous leishmaniasis that were co-infected with human immunodeficiency virus. The causative parasites were cha...
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PMID: 21633027
PDF is available here.
Abstract
We report on an alternative diagnostic method based on presence of the S. haematobium-specific Dra 1, 121 bp repeat fragment in human urine. A novel method of collecting the urine specimens in the field and filtering them through heavy Whatman No. 3 paper was introduced. After drying, the samples re...
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PMID: 21633040
PDF is available here.
Abstract
We explored the mechanism underlying natural variation in longevity within natural populations using the model budding yeast, Saccharomyces cerevisiae. We analyzed whole-genome gene expression in four progeny of a natural S. cerevisiae strain that display differential replicative aging. Genes with d...
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PMID: 21306556
PDF is available here.
Abstract
Objective-To investigate shedding of chlamydiae from conjunctiva and genital tracts of cats without clinical signs of conjunctivitis or other infectious disease in relation to their titers of serum antibodies against chlamydiae and to serum amyloid A (SAA) and serum α(1)-acid glycoprotein (AGP) conc...
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PMID: 21627527
PDF is available here.
Suresh B Boppana,
Shannon A Ross,
Masako Shimamura,
April L Palmer,
Amina Ahmed,
Marian G Michaels,
Pablo J Sánchez,
David I Bernstein,
Robert W Tolan,
Zdenek Novak,
Nazma Chowdhury,
William J Britt,
Karen B Fowler and
National Institute on Deafness and Other Communication Disorders CHIMES Study
Abstract
We compared real-time PCR assays of liquid-saliva and dried-saliva specimens with rapid culture of saliva specimens obtained at birth.
A total of 177 of 34,989 infants (0.5%; 95% confidence interval [CI], 0.4 to 0.6) were positive for CMV, according to at least one of the three metho...
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PMID: 21631323
PDF is available here.
Abstract
We evaluate its association with human and murine atherosclerosis, and assess the role of platelet-derived NPY in lesion vulnerability. NPY immunoreactivity (NPY-ir) was measured in the platelet-poor and platelet-rich (PRP) plasmas, and NPY receptors (mitogenic Y1R and angiogenic Y2 and Y5Rs), CD26/...
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PMID: 21468772
PDF is available here.
Abstract
We describe and conduct a pilot test of a multiplex sequencing strategy suitable for achieving total reads of > 300 bases per extracted DNA molecule on the IGA. Results show that all proposed primers produce products of the expected size and that correct sequences can be obtained, with all propo...
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PMID: 21361774
PDF is available here.
Abstract
We describe the sediment metagenome from the oligotrophic Brazos-Trinity Basin (Site 1320) and show similarities and differences with the dataset from the Pacific Peru Margin (Site 1229) and other pyrosequenced datasets. The microbial community found at Integrated Ocean Drilling Program Site 1320 li...
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PMID: 21209666
PDF is available here.
Abstract
The diagnostic approach to thyroid nodules generally starts with FNA cytology. However, approximately one-fifth of cytologic evaluations yield indeterminate cytological findings but only 20% of cases with indeterminate thyroid nodule cytology have a cancer diagnosis, emphasizing the...
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PMID: 20607744
PDF is available here.
Abstract
Small-colony variants (SCVs) of Staphylococcus aureus represent a slow-growing subpopulation causing chronic and relapsing infections due to their physiological adaptation on an intracellular lifestyle. In this first proteomic study on physiological changes associated with a natural,...
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PMID: 21595038
PDF is available here.
Abstract
Cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that modulates many biological processes. Although its role in bacterial pathogenesis during mammalian infection has been documented, the role of c-di-GMP in a pathogen's life cycle within a vector host is less understood....
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PMID: 21738477
PDF is available here.
Abstract
DNA-based techniques have proved to be very useful methods to study trophic relationships between pests and their natural enemies. However, most predators are best defined as omnivores, and the identification of plant-specific DNA should also allow the identification of the plant spe...
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PMID: 21092379
PDF is available here.
Abstract
We report a case suffering from lateral medullary syndrome resulting from brainstem tuberculoma which has not been reported so far in the literature. This patient was started on antituberculous chemotherapy and repeat magnetic resonance imaging of the cranium revealed regression of the lesion....
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PMID: 21751596
PDF is available here.
Huipeng H Pan,
Dong D Chu,
Daqing D Ge,
Shaoli S Wang,
Qingjun Q Wu,
Wen W Xie,
Xiaoguo X Jiao,
Baiming B Liu,
Xin X Yang,
Nina N Yang,
Qi Q Su,
Baoyun B Xu and
Youjun Y Zhang
Abstract
We determined the biotypes composition in 61 whitefly populations and their distribution across 19 provinces in China. Our research revealed that only biotypes B and Q have been found in the field in 2009 in China. Among them, biotype Q was dominant in 44 locations (100.0%) and biotype B was dominan...
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PMID: 21735919
PDF is available here.
Abstract
We investigated the prevalence of this newly identified pathogenic bacterium in cooling towers by quantitative PCR (qPCR) and its possible relationship with Legionella pneumophila co-infection. Our results show Simkania detection in 2 of 70 cooling towers analyzed. To our knowledge, this report is t...
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PMID: 21942196
PDF is available here.