Qian Wang,
Andrew L Rozelle,
Christin M Lepus,
Carla R Scanzello,
Jason J Song,
D Meegan Larsen,
James F Crish,
Gurkan Bebek,
Susan Y Ritter,
Tamsin M Lindstrom,
Inyong Hwang,
Heidi H Wong,
Leonardo Punzi,
Angelo Encarnacion,
Mehrdad Shamloo,
Stuart B Goodman,
Tony Wyss-Coray,
Steven R Goldring,
Nirmal K Banda,
Joshua M Thurman,
Reuben Gobezie,
Mary K Crow,
V Michael Holers,
David M Lee and
William H Robinson
Abstract
We identify a central role for the inflammatory complement system in the pathogenesis of osteoarthritis. Through proteomic and transcriptomic analyses of synovial fluids and membranes from individuals with osteoarthritis, we find that expression and activation of complement is abnormally high in hum...
|
PMID: 22057346
PDF is available here.
Qian Wang,
Andrew L Rozelle,
Christin M Lepus,
Carla R Scanzello,
Jason J Song,
D Meegan Larsen,
James F Crish,
Gurkan Bebek,
Susan Y Ritter,
Tamsin M Lindstrom,
Inyong Hwang,
Heidi H Wong,
Leonardo Punzi,
Angelo Encarnacion,
Mehrdad Shamloo,
Stuart B Goodman,
Tony Wyss-Coray,
Steven R Goldring,
Nirmal K Banda,
Joshua M Thurman,
Reuben Gobezie,
Mary K Crow,
V Michael Holers,
David M Lee and
William H Robinson
Abstract
We identify a central role for the inflammatory complement system in the pathogenesis of osteoarthritis. Through proteomic and transcriptomic analyses of synovial fluids and membranes from individuals with osteoarthritis, we find that expression and activation of complement is abnormally high in hum...
|
PMID: 22057346
PDF is available here.
Qian Wang,
Andrew L Rozelle,
Christin M Lepus,
Carla R Scanzello,
Jason J Song,
D Meegan Larsen,
James F Crish,
Gurkan Bebek,
Susan Y Ritter,
Tamsin M Lindstrom,
Inyong Hwang,
Heidi H Wong,
Leonardo Punzi,
Angelo Encarnacion,
Mehrdad Shamloo,
Stuart B Goodman,
Tony Wyss-Coray,
Steven R Goldring,
Nirmal K Banda,
Joshua M Thurman,
Reuben Gobezie,
Mary K Crow,
V Michael Holers,
David M Lee and
William H Robinson
Abstract
We identify a central role for the inflammatory complement system in the pathogenesis of osteoarthritis. Through proteomic and transcriptomic analyses of synovial fluids and membranes from individuals with osteoarthritis, we find that expression and activation of complement is abnormally high in hum...
|
PMID: 22057346
PDF is available here.
Abstract
We have developed a new type of molecular-targeted cancer therapy, photoimmunotherapy (PIT), that uses a target-specific photosensitizer based on a near-infrared (NIR) phthalocyanine dye, IR700, conjugated to monoclonal antibodies (mAbs) targeting epidermal growth factor receptors. Cell death was in...
|
PMID: 22057348
PDF is available here.
Abstract
We have developed a new type of molecular-targeted cancer therapy, photoimmunotherapy (PIT), that uses a target-specific photosensitizer based on a near-infrared (NIR) phthalocyanine dye, IR700, conjugated to monoclonal antibodies (mAbs) targeting epidermal growth factor receptors. Cell death was in...
|
PMID: 22057348
PDF is available here.
Abstract
We have developed a new type of molecular-targeted cancer therapy, photoimmunotherapy (PIT), that uses a target-specific photosensitizer based on a near-infrared (NIR) phthalocyanine dye, IR700, conjugated to monoclonal antibodies (mAbs) targeting epidermal growth factor receptors. Cell death was in...
|
PMID: 22057348
PDF is available here.
Abstract
We report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surroun...
|
PMID: 22057345
PDF is available here.
Abstract
We report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surroun...
|
PMID: 22057345
PDF is available here.
Abstract
We report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surroun...
|
PMID: 22057345
PDF is available here.
Qian Wang,
Andrew L Rozelle,
Christin M Lepus,
Carla R Scanzello,
Jason J Song,
D Meegan Larsen,
James F Crish,
Gurkan Bebek,
Susan Y Ritter,
Tamsin M Lindstrom,
Inyong Hwang,
Heidi H Wong,
Leonardo Punzi,
Angelo Encarnacion,
Mehrdad Shamloo,
Stuart B Goodman,
Tony Wyss-Coray,
Steven R Goldring,
Nirmal K Banda,
Joshua M Thurman,
Reuben Gobezie,
Mary K Crow,
V Michael Holers,
David M Lee and
William H Robinson
Abstract
We identify a central role for the inflammatory complement system in the pathogenesis of osteoarthritis. Through proteomic and transcriptomic analyses of synovial fluids and membranes from individuals with osteoarthritis, we find that expression and activation of complement is abnormally high in hum...
|
PMID: 22057346
PDF is available here.
Abstract
We have developed a new type of molecular-targeted cancer therapy, photoimmunotherapy (PIT), that uses a target-specific photosensitizer based on a near-infrared (NIR) phthalocyanine dye, IR700, conjugated to monoclonal antibodies (mAbs) targeting epidermal growth factor receptors. Cell death was in...
|
PMID: 22057348
PDF is available here.
Abstract
We report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surroun...
|
PMID: 22057345
PDF is available here.
Qian Wang,
Andrew L Rozelle,
Christin M Lepus,
Carla R Scanzello,
Jason J Song,
D Meegan Larsen,
James F Crish,
Gurkan Bebek,
Susan Y Ritter,
Tamsin M Lindstrom,
Inyong Hwang,
Heidi H Wong,
Leonardo Punzi,
Angelo Encarnacion,
Mehrdad Shamloo,
Stuart B Goodman,
Tony Wyss-Coray,
Steven R Goldring,
Nirmal K Banda,
Joshua M Thurman,
Reuben Gobezie,
Mary K Crow,
V Michael Holers,
David M Lee and
William H Robinson
Abstract
We identify a central role for the inflammatory complement system in the pathogenesis of osteoarthritis. Through proteomic and transcriptomic analyses of synovial fluids and membranes from individuals with osteoarthritis, we find that expression and activation of complement is abnormally high in hum...
|
PMID: 22057346
PDF is available here.
Abstract
We have developed a new type of molecular-targeted cancer therapy, photoimmunotherapy (PIT), that uses a target-specific photosensitizer based on a near-infrared (NIR) phthalocyanine dye, IR700, conjugated to monoclonal antibodies (mAbs) targeting epidermal growth factor receptors. Cell death was in...
|
PMID: 22057348
PDF is available here.
Abstract
We report a dual-modality intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo using a combination of optical frequency domain imaging (OFDI) and near-infrared fluorescence (NIRF) imaging. By providing simultaneous molecular information in the context of the surroun...
|
PMID: 22057345
PDF is available here.