Abstract
Morphofunctional and biochemical properties of erythrocyte membrane were investigated in early postnatal ontogenesis in rats in norm and after prenatal immobilization stress. The transient decrease of erythrocyte membranes stability was revealed in the control rats. The ability to er...
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PMID: 21961297
PDF is available here.
Abstract
These results allow refinement, clarification, and correction of earlier descriptions, which are reviewed. The relative taxonomic importance of various morphological characters of the first instars of necrophagous blow flies is discussed, and details of the cephaloskeleton and the spinulation of the...
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PMID: 21845931
PDF is available here.
Abstract
We have been able to show that SODIS is effective against a variety of previously untested waterborne organisms and with A. castellanii cysts the addition of micro-molar concentrations of riboflavin can enhance cyst inactivation. However, care must be taken as Ascaris larvae continue to develop insi...
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PMID: 21635868
PDF is available here.
Abstract
We developed an automated method, binarization-based extraction of alignment score (BEAS), to determine cell orientation distribution in a wide variety of microscopic images. This method combines a sequenced application of median and band-pass filters, locally adaptive thresholding approaches and im...
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PMID: 21370940
PDF is available here.
Abstract
We present evidence that A. terreus AC are phenotypically distinct from PC and can be potent activators of the innate immune mechanism thus possibly playing a role in this organism's pathogenesis....
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PMID: 21543882
PDF is available here.
Abstract
We report on a patient suffering from cystic fibrosis who developed disseminated fungal infection due to a rare Scopulariopsis species, Microascus cirrosus, after heart and lung transplantation. Despite antifungal combination therapy with voriconazole and caspofungin, the patient died 4 weeks after...
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PMID: 21543579
PDF is available here.
Abstract
We report here a case of disseminated skin infection caused by Mucor velutinosus, a recently described new species. We believe this to be the first published report of a clinical case of mucormycosis due to M. velutinosus, as well as a rare case of dissemination from a deep site to skin.
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PMID: 21543575
PDF is available here.
Abstract
To provide a rapid, simple, accurate and reproducible identification method from which Cordyceps sinensis can be distinguished from other species.
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PMID: 21842637
PDF is available here.
Abstract
We investigated the trophosome of S. contortum from the Gulf of Mexico, using light and electron microscopy. We show that this organ derives from the visceral mesoderm and propose that the trophosome of the sister clade Vestimentifera and Sclerolinum is a homologous character. Like that of juvenile...
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PMID: 21551450
PDF is available here.
Abstract
More than 90% of venous malformations (VM) are associated with pain, which is presumed related to phlebolith formation and subsequent nociceptive mediator release. Increasing evidence supports a link between angiogenesis and nerve patterning. Since vascular malformations are aberrati...
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PMID: 20705529
PDF is available here.
Abstract
This study describes the killer phenotypes of tropical environmental yeasts and the inhibition effects of the culture filtrates on the biofilm of Candida albicans. A total of 26 (10.5%) of 258 yeast isolates obtained from an environmental sampling study demonstrated killer activity to Candida species...
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PMID: 21602784
PDF is available here.
Abstract
Transmission of soil-transmitted helminthes infection is by faecal oral route, and is influenced by food preference. Kelantanese love to consume ulam which are raw vegetables and herbs. Some of the herbs grow on grounds with high humidity and are abundant near drainage areas, these are also places wi...
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PMID: 21602786
PDF is available here.
Abstract
A case of Acremonium kiliense peritonitis is described. Diagnosis was established by repeated isolation of the fungus from peritoneal dialysate and by its identification on the basis of morphological characteristics and sequencing of internal transcribed spacer (ITS) regions of ribosomal DNA (rDNA)....
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PMID: 21450966
PDF is available here.
Abstract
We report the first documented case of a posttraumatic fungal keratitis caused by Neosartorya udagawae. The patient was empirically treated with fluconazole until a corneal scraping grew an Aspergillus fumigatus-like fungus, and itraconazole therapy was then established. A sequence-based approach ass...
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PMID: 21450961
PDF is available here.
Abstract
We monitored cellular and molecular responses of oyster haemocytes by light microscopy, flow cytometry and real-time PCR 1, 2, 4 and 8h p.i. Light microscopy was used to measure parasite phagocytosis by oyster haemocytes. Parasites were observed inside haemocytes 1h p.i. and the parasite number incr...
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PMID: 21447342
PDF is available here.
Abstract
We present a case of a human immunodeficiency virus (HIV)-infected patient with PML and cerebellar atrophy. In addition to a compartmentalization of JCV strains between urine, cerebrospinal fluid, and cerebellum, specific rearrangements in the JCV regulatory region were observed in the cerebellum, r...
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PMID: 21430099
PDF is available here.
Abstract
We characterized metabolic C. elegans mutants by using novel and feasible BODIPY 493/503-based fat staining and flow cytometry approaches. Fixative as well as vital BODIPY staining procedures visualize major fat stores, preserve native lipid droplet morphology, and allow quantification of fat conten...
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PMID: 21421847
PDF is available here.
Abstract
This study demonstrated the value of an automated approach to the analysis of FISH slides, affording the benefit of high-throughput while providing the user with the necessary images and tools to quickly and accurately report a case. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society....
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PMID: 21413160
PDF is available here.
Abstract
We showed that the introduction of the tgd mutations into fad6 mutant backgrounds led to drastic reductions in relative amounts of thylakoid lipids. Moreover, the tgd1-1 fad6 and tgd4-3 fad6 double mutants were deficient in polyunsaturated fatty acids in chloroplast membrane lipids, and severely com...
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PMID: 21358271
PDF is available here.
Abstract
A method that provides objective data to complement the hair analysts' microscopic observations, which is non-destructive, would be of obvious benefit in the forensic examination of hairs. This paper reports on the use of objective colour measurement and image analysis techniques of auto-montaged ima...
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PMID: 21334579
PDF is available here.
Abstract
We measured Brownian displacements of microspheres exposed to light of varying intensities and wavelengths. Displacements were consistently diminished in an intensity-dependent and wavelength-dependent fashion, and center-to-center distances between microspheres were shifted to higher values. We con...
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PMID: 21287689
PDF is available here.
Abstract
We investigated the utility of a visual discrimination model (VDM) and other distortion metrics for predicting JPEG 2000 bit rates corresponding to visually lossless compression of virtual slides for breast biopsy specimens. Threshold bit rates were determined experimentally with human observers for...
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PMID: 20875970
PDF is available here.
A A Mendoza,
E E Castillo,
N N Gamarra,
T T Huamán,
M M Perea,
Y Y Monroi,
R R Salazar,
J J Coronel,
M M Acurio,
G G Obregón,
M M Roper,
C C Bonilla,
L L Asencios and
D A J DA Moore
Abstract
To deliver rapid isoniazid (INH) and rifampicin (RMP) drug susceptibility testing (DST) close to the patient, we designed a decentralisation process for the microscopic observation drug susceptibility (MODS) assay in Peru and evaluated its reliability.
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PMID: 21219684
PDF is available here.
Abstract
The objective was to examine the use of a tailor-made DNA microarray containing probes representing the vaginal microbiota to examine bacterial vaginosis.
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PMID: 21272848
PDF is available here.
Abstract
We conclude that this method would aid in early and better diagnosis and treatment planning of oral premalignant and malignant lesions by assessing the various vascular patterns in the mucosa....
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PMID: 21339913
PDF is available here.
Abstract
Pathology is a bridging discipline that involves both basic and clinical biomedical sciences. In this context, it includes both descriptive and mechanistic approaches, with the final goals of further understanding the anatomic and functional changes and underlying molecular events involved in disease...
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PMID: 21424058
PDF is available here.
Abstract
Therefore, persistent infection of cell cultures with FMDV is successfully established with some distinctive features. It would be worthwhile to further investigate the mechanisms of viral persistence....
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PMID: 21492421
PDF is available here.
Abstract
The high infection rate of canine thelaziosis herein reported suggests that practitioners should include this eye infection amongst differential diagnoses of ocular diseases in dogs from this area of Spain or that moving across this area of Spain. Based on the high infection prevalence recorded, the...
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PMID: 21791108
PDF is available here.
Abstract
Although the bitch and the male had visited neighboring Galicia (northwestern Spain), where the disease is endemic, incursion of this piroplasm into northern Portugal is evident and infection of the non-traveled pup was due to either vertical transmission or autochthonous tick infection....
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PMID: 21489238
PDF is available here.
Abstract
We evaluated the therapeutic potential of parthenolide against bladder cancer and its mechanism of action. Treatment of bladder cancer cells with parthenolide resulted in a significant decrease in cell viability. Parthenolide induced apoptosis through the modulation of Bcl-2 family proteins and poly...
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PMID: 21829151
PDF is available here.
Abstract
We implemented a strategy for the visualization of morphological changes of dendritic spines over tens of minutes at a lateral resolution of 25 to 65 nm. We have generated a low-affinity photoconvertible probe, capable of reversibly binding to actin and thus allowing long-term photoactivated localiz...
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PMID: 21264214
PDF is available here.
Abstract
A dedicated microscopy imaging system including automated positioning, focusing, image acquisition, and image analysis was developed to characterize a yeast population with regard to cell morphology. This method was used to monitor a stress-model alcoholic fermentation with Saccharom...
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PMID: 21290616
PDF is available here.
Abstract
A local cartilage injury can trigger development of posttraumatic osteoarthritis (OA). Surgical methods have been developed for repairing cartilage injuries. Objective and sensitive methods are needed for planning an optimal surgery as well as for monitoring the surgical outcome. In...
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PMID: 21244982
PDF is available here.
Abstract
The sensitivity of a rapid test versus microscopy of blood samples was studied while examining 7983 dwellers from the republic's endemic areas. The results of blood testing in the Pyanj and Shurobod districts showed agreement with those of blood microscopy. However, its sensitivity i...
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PMID: 21932547
PDF is available here.
Abstract
Clinical Relevance The presence of enamel at the cervical margin of a class II preparation increases the fracture strength of the composite restoration at the marginal ridge, but fractures are more complicated when they occur.
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PMID: 21777100
PDF is available here.
Abstract
These results indicated that multiple regulatory mechanisms might be involved. The high elevated expression of some genes belonging to the mycoparasite and the host suggest that these genes play an important role during the mycoparasitic process and host defense respectively....
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PMID: 21193602
PDF is available here.
Abstract
We verified that some brown trout renal components undergo sex dependent seasonal variations, suggesting a morphological adaptation of the components to accomplish physiological needs. These findings constitute a baseline for launching studies to know which factors govern the morphological variation...
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PMID: 20932361
PDF is available here.
Abstract
We verified that some brown trout renal components undergo sex dependent seasonal variations, suggesting a morphological adaptation of the components to accomplish physiological needs. These findings constitute a baseline for launching studies to know which factors govern the morphological variation...
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PMID: 20932361
PDF is available here.
Abstract
Precise information about the size, shape, temporal dynamics, and spatial distribution of cells is beneficial for the understanding of cell behavior and may play a key role in drug development, regenerative medicine, and disease research. The traditional method of manual observation...
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PMID: 20872884
PDF is available here.
Abstract
To assess the agreement among clinical, Heidelberg Retina Tomograph (HRT), and optic disc photography in the optic disc diameter measurement.
Prospective, observational study of 55 eyes of 55 subjects who underwent horizontal and vertical optic disc diameter measurements with +90 diopter lens on sli...
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PMID: 20179627
PDF is available here.
Abstract
To determine the histopathological pattern in childhood glomerulonephritis (CGN).
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PMID: 21381552
PDF is available here.
Abstract
We report the implementation of a fully on-chip, lensless, sub-pixel resolving optofluidic microscope (SROFM). The device utilizes microfluidic flow to deliver specimens directly across a complementary metal oxide semiconductor (CMOS) sensor to generate a sequence of low-resolution (LR) projection i...
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PMID: 20877904
PDF is available here.
Abstract
Remodeling of small resistance arteries is an early sign of target organ damage in hypertension. Peripheral capillary morphology abnormalities in hypertension are not well studied. The study objective was to determine whether altered capillary morphology is associated with SBP, DBP, or both in indiv...
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PMID: 20724940
PDF is available here.
Abstract
Our estimates produced 1560±20 cells in an islet equivalent (volume of 150-μm diameter sphere), of which 1140±15 were β-cells. To test whether LM analysis of the same tissue samples could provide reasonable estimates of purity of the islet preparations, volume fraction of the islet tissue was me...
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PMID: 20697378
PDF is available here.
Abstract
We examined nuclei counting for measuring the total number of cells in islet preparations, and we combined it with morphological analysis by light microscopy (LM) for estimating the volume fraction of islets in impure preparations. Cells and islets were disrupted with lysis solution and shear, and a...
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PMID: 20697375
PDF is available here.
Abstract
We examined the kinetics and molecular mechanisms of neutrophil recruitment to sites of focal hepatic necrosis in vivo. Adenosine triphosphate released from necrotic cells activated the Nlrp3 inflammasome to generate an inflammatory microenvironment that alerted circulating neutrophils to adhere wit...
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PMID: 20947763
PDF is available here.
Abstract
Three laterally substituted liquid crystals were synthesized in order to investigate the effect of a lateral biforked chain on the thermal and analytical properties. The mesogenic molecules have the same core containing four aromatic rings connected by two ester and one diazo linkages, they differ b...
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PMID: 20828705
PDF is available here.
Abstract
We describe a novel tract-specific framework that enables the examination of white matter morphometry at both the macroscopic and microscopic scales. The framework leverages the skeleton-based modeling of sheet-like white matter fasciculi using the continuous medial representation, which gives a nat...
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PMID: 20547469
PDF is available here.
Abstract
Our results showed that NLOM can reveal different regeneration processes of collagen in nontreated and MSC-treated wound dermis. Specifically, the temporal increases in the intensity of second-harmonic-generation signals can quantify kinetic properties of collagen regeneration. Orientation analysis...
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PMID: 20102266
PDF is available here.
Abstract
We apply a combination of various linear and non-linear imaging modalities, i.e. fluorescence, Raman and second-harmonic generation microscopy, to study the morphochemistry of basal cell carcinoma. The joint information content obtained by such multimodal approach in studying various aspects of the...
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PMID: 20648521
PDF is available here.