Abstract
We propose an alternative approach based on omnibus tests of equality of means and variances and in subject-by-subject analyses (where applicable), and we show that these tests have adequate Type I error rates and power. The approach is illustrated with a re-analysis of published data from a signal...
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PMID: 22059346
PDF is available here.
Abstract
The aim of this work is to examine the pentafactorial validity of the AF5 Self-Concept Questionnaire in Spanish and Chilean young adults. From the responses of a total of 4,383 young adults aged 17 to 22 years (1,918 Spanish, 44%, and 2,465 Chilean, 56%) it was analyzed the reliabili...
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PMID: 22059311
PDF is available here.
Abstract
We have explored the psychometric properties and construct validity of the Turkish adaptation of the Mathematics Teacher Efficacy Belief Instrument developed by Enochs, Smith, & Huinker (2000) for in-service mathematics teachers. The instrument distinguishes between two dimensions of efficacy belief...
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PMID: 22059339
PDF is available here.
Abstract
Apoptosis is the process of programmed cell death. It is a ubiquitous, controlled process consuming cellular energy and designed to avoid cytokine release despite activation of local immune cells, which clear the cell fragments. The process occurs during organ development and in main...
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PMID: 21241798
PDF is available here.
Abstract
Apoptosis is the process of programmed cell death. It is a ubiquitous, controlled process consuming cellular energy and designed to avoid cytokine release despite activation of local immune cells, which clear the cell fragments. The process occurs during organ development and in main...
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PMID: 21241798
PDF is available here.
Abstract
Apoptosis is the process of programmed cell death. It is a ubiquitous, controlled process consuming cellular energy and designed to avoid cytokine release despite activation of local immune cells, which clear the cell fragments. The process occurs during organ development and in main...
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PMID: 21241798
PDF is available here.
Abstract
This paper demonstrates that a recently proposed dynamical model for the ecology of Easter Island admits periodic and chaotic attractors, not previously reported. Such behavior may more realistically depict the population dynamics of general ecosystems and illustrates the power of simple models to pr...
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PMID: 21933513
PDF is available here.
Abstract
We examined some types of transients found in time series of events that lend themselves to symbolic dynamics analysis through the method of orbital decomposition, which is based on the principle that chaotic series arise from coupled oscillators. Synthetic data sets were constructed to study the im...
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PMID: 21933515
PDF is available here.
Abstract
In order to evaluate the efficacy of an antibacterial therapy, three basic PK/PD indexes were defined: the ratio between the maximum drug concentration obtained after a single dose and minimum inhibitory concentration MIC (CMAX/MIC), the ratio between the area under the curve of dependence between th...
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PMID: 21928725
PDF is available here.
George G Howard,
Leslie A LA McClure,
Claudia S CS Moy,
Monika M MM Safford,
Mary M Cushman,
Suzanne E SE Judd,
Brett M BM Kissela,
Dawn O DO Kleindorfer,
Virginia J VJ Howard,
David J DJ Rhodes,
Paul P Muntner and
Hemant K HK Tiwari
Abstract
Longitudinal cohort studies normally identify and adjudicate incident events detected during follow-up by retrieving medical records. There are several reasons why the adjudication process may not be successfully completed for a suspected event including the inability to retrieve med...
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PMID: 21804050
PDF is available here.
Abstract
We compiled a data set of larval host use and adult nectar sources for 995 butterfly and moth species (Lepidoptera) in central Europe. Using a phylogenetic generalized least squares approach, we found that those Lepidoptera that fed on a wide range of plant species as larvae were also nectar feeding...
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PMID: 21828993
PDF is available here.
Abstract
We investigated the degree to which several risk factors could explain this rise in notifications and the younger age profile....
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PMID: 21851769
PDF is available here.
Abstract
Linear, quadratic, and artificial neural network (ANN)-based metamodels were developed for predicting the extent of anthrax spore inactivation by chlorine dioxide in a ventilated three-dimensional space over time from computational fluid dynamics model (CFD) simulation data. Dimensio...
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PMID: 22010381
PDF is available here.
Abstract
Qualitative models allow understanding the relation between the structure and the dynamics of gene regulatory networks. The dynamical properties of these models can be automatically analysed by means of formal verification methods, like model checking. This facilitates the model-vali...
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PMID: 22010757
PDF is available here.
Abstract
We estimated the effective propagation number, which reflects the relative importance of contrasting within-host control mechanisms through time and is sensitive to the inoculating parasite dose. Our analysis showed that the capacity of innate responses to restrict initial parasite growth saturates...
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PMID: 21852493
PDF is available here.
Abstract
We shall address. We shall point out the confusions about the conventional identity in the min-plus algebra and present an analytical expression of the asymptotic identity that may not cause confusions....
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PMID: 21822446
PDF is available here.
Abstract
Curbs are commonly used on roadways for drainage management, access control, and other positive functions. However, curbs may also bring about unfavorable effects on drivers' behavior and vehicle stability when hitting curbs, especially for high-speed roadways. The objective of this article is to inv...
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PMID: 21823949
PDF is available here.
Abstract
We propose a model for the relationship between road traffic accidents and conflicts recorded by drive recorders (DRs)....
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PMID: 21823939
PDF is available here.
Abstract
We examined the correlation between the visual field index (VFI) and mean deviation (MD), as well as the correlation on VFI slope and MD slope.
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PMID: 21882585
PDF is available here.
Abstract
To examine the implementation of estimated date of discharge (EDD) for planned admissions and admissions via the emergency department, to assess the variance between EDD and the actual date of discharge (ADD), and to explore the determinants of delayed discharge in a tertiary referral centre, Sydney,...
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PMID: 21871199
PDF is available here.
Abstract
We conducted population-based telephone surveys in four North Carolina counties to determine the number of social interactions between individuals during the 2007-2008 influenza season. Influenza activity was monitored through sentinel medical practices. Among 3845 adults, the number of social conta...
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PMID: 20943002
PDF is available here.
Abstract
We performed a population-based study linking HCV notifications in New South Wales, Australia with their hospital (July 2000 to June 2006), hepatitis B virus (HBV) and HIV notification, and death records. Poisson models were used to calculate hospitalization rate ratios (RRs) for all-cause, illicit...
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PMID: 21087540
PDF is available here.
Abstract
Hepatitis E virus (HEV) infection is as an emerging disease of global importance because it is one of the major causes of acute hepatitis worldwide. There are few reports on the incidence of HEV in the USA. For better assessing the burden of primary HEV infection as well as understanding the epidemio...
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PMID: 20854712
PDF is available here.
Abstract
We reviewed the literature to determine if specific disease parameters or medication use could be used to better characterize fracture risk in individuals with rheumatoid arthritis. Although many studies document a correlation between various parameters of disease activity or severity and decreased...
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PMID: 21810523
PDF is available here.
Abstract
The worldwide prevalence of smoking has been estimated at about 50% in men, and 10% in women, with larger variations among different populations studied. Smoking has been shown to affect many organ systems resulting in severe morbidity and increased mortality. In addition, smoking has been identified...
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PMID: 21810524
PDF is available here.
Abstract
Risk factors for fracture can be purely skeletal, e.g., bone mass, microarchitecture or geometry, or a combination of bone and falls risk related factors such as age and functional status. The remit of this Task Force was to review the evidence and consider if falls should be incorporated into the FR...
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PMID: 21810525
PDF is available here.
Abstract
The 2010 Position Development Conference addressed four questions related to the impact of previous fractures on 10-year fracture risk as calculated by FRAX(®). To address these questions, PubMed was searched on the keywords "fracture, epidemiology, osteoporosis." Titles of retrieved articles were r...
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PMID: 21810526
PDF is available here.
Didier B DB Hans,
John A JA Kanis,
Sanford S Baim,
John P JP Bilezikian,
Neil N Binkley,
Jane A JA Cauley,
Juliet E JE Compston,
Cyrus C Cooper,
Bess B Dawson-Hughes,
Ghada G El-Hajj Fuleihan,
William D WD Leslie,
E Michael EM Lewiecki,
Marjorie M MM Luckey,
Eugene V EV McCloskey,
Socrates E SE Papapoulos,
Catalina C Poiana,
René R Rizzoli and
Abstract
The International Society for Clinical Densitometry (ISCD) and the International Osteoporosis Foundation (IOF) convened the FRAX(®) Position Development Conference (PDC) in Bucharest, Romania, on November 14, 2010, following a two-day joint meeting of the ISCD and IOF on the "Interpretation and Use...
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PMID: 21810521
PDF is available here.
Abstract
The World Health Organization fracture risk assessment tool, FRAX(®), is an advance in clinical care that can assist in clinical decision-making. However, with increasing clinical utilization, numerous questions have arisen regarding how to best estimate fracture risk in an individual patient. Recog...
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PMID: 21810522
PDF is available here.
Abstract
Given the significant impact the use of glucocorticoids can have on fracture risk independent of bone density, their use has been incorporated as one of the clinical risk factors for calculating the 10-year fracture risk in the World Health Organization's Fracture Risk Assessment Tool (FRAX(®)). Lik...
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PMID: 21810527
PDF is available here.
Abstract
results suggest that brain MRI measures of WMH (attributed to cerebrovascular disease) and childhood intelligence significantly contribute to late life fluid cognitive ability but not to the trajectory of age-related change in fluid intelligence. We also show that age is associated with the cognitiv...
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PMID: 21749994
PDF is available here.
Abstract
Hypofractionated prostate radiotherapy may benefit from both volumetric modulated are therapy (VMAT) due to shortened treatment time and intrafraction real-time monitoring provided by implanted radiofrequency(RF) transponders. The authors investigate dosimetrically driven action thre...
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PMID: 21858997
PDF is available here.
Abstract
These results can offer guidance in the selection of CTV margins for treatment with the CyberKnife....
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PMID: 21859002
PDF is available here.
Abstract
Many planning methods for high dose rate (HDR) brachytherapy require an iterative approach. A set of computational parameters are hypothesized that will give a dose plan that meets dosimetric criteria. A dose plan is computed using these parameters, and if any dosimetric criteria are...
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PMID: 21859003
PDF is available here.
Abstract
This work describes a spatially variant mixture model constrained by a Markov random field to model high angular resolution diffusion imaging (HARDI) data. Mixture models suit HARDI well because the attenuation by diffusion is inherently a mixture. The goal is to create a general mod...
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PMID: 21859036
PDF is available here.
Abstract
Basic patient and tumor characteristics impact overall survival of head and neck squamous cell carcinoma patients. Severe malnutrition, defined as weight loss > 10% in 6 months preceding primary tumor diagnosis, impacts overall survival as well. Little attention has been paid to the interaction betwe...
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PMID: 21802345
PDF is available here.
Abstract
The quantitative measurements of uncertainties regarding the contents of hazardous trace elements (HTEs) serve as a basis for better assessment of the geochemistry and mineralogical characteristics of coals and their environmental impacts. In this paper, by using bootstrap simulation methodology, a q...
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PMID: 21850830
PDF is available here.
Abstract
We determined the relationship between 10-yr fracture probability and subsequent fracture burden in 36,730 women and 2873 men aged 50yr and older. Using a major fracture probability cutoff of 20%, 29.4% of major osteoporotic fractures were identified in women and 4.9% in men. Based on a hip fracture...
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PMID: 21723761
PDF is available here.
Abstract
We simulated relative miscalibration error in 10% increments from -50% to +50% relative to a correctly calibrated FRAX(®) model. We found that small changes in model calibration (even on the order of 10%) had large effects on the number of individuals qualifying for treatment. There was a steep gra...
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PMID: 21723769
PDF is available here.
Abstract
A ground reaction based method is proposed to evaluate the hypothesis that a stabilization phase occurs in transitions towards erect posture, following the macroscopic movement and preceding the quiet final erect posture, whose aim is to control and dissipate the residual inertial un...
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PMID: 21708508
PDF is available here.
Abstract
The efficacy of computed tomography (CT) screening for lung cancer remains controversial because results from the National Lung Screening Trial are not yet available. In this study, the authors used data from a single-arm CT screening trial to estimate the mortality reduction using a modeling-based a...
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PMID: 21656748
PDF is available here.
Toshiaki T Watanabe,
Takashi T Kobunai,
Yoko Y Yamamoto,
Hiroki H Ikeuchi,
Keiji K Matsuda,
Soichiro S Ishihara,
Keijiro K Nozawa,
Hisae H Iinuma,
Takamitsu T Kanazawa,
Toshiaki T Tanaka,
Tadashi T Yokoyama,
Tsuyoshi T Konishi,
Kiyoshi K Eshima,
Yohichi Y Ajioka,
Toshifumi T Hibi,
Mamoru M Watanabe,
Tetsuichiro T Muto and
Hirokazu H Nagawa
Abstract
We identified 20 genes showing differential expression in UC-Ca and UC-NonCa patients, including cancer-related genes such as CYP27B1, RUNX3, SAMSN1, EDIL3, NOL3, CXCL9, ITGB2, and LYN. Using these 20 genes, we were able to build a predictive model that distinguished patients with and without UC-Ca...
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PMID: 21859567
PDF is available here.
Abstract
We measured variability in diarrhea prevalence among children < 5 years of age living in squatter settlements in central Karachi, Pakistan. We pooled data from non-intervention control households from studies conducted from 2002 through 2006. The prevalence of diarrhea varied on average by 29% from...
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PMID: 21633021
PDF is available here.
Abstract
We use a probabilistic risk assessment approach to estimate the risks to Africans from inhalation, dermal, and oral exposures to the newer LLINs with permethrin, α-cypermethrin, or deltamethrin as the insecticide active ingredient. We estimated exposures to LLINs using 17 age groups to incorporate...
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PMID: 21633033
PDF is available here.
Abstract
Previous research on female caregivers of elderly relatives with dementia has demonstrated that caregiving self-efficacy (SE) is associated with reduced cumulative health risk. The overarching aim of the current study was to expand on that research by exploring whether depressive sym...
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PMID: 21636582
PDF is available here.
Abstract
In order to harness the computational capacity of dissociated cultured neuronal networks, it is necessary to understand neuronal dynamics and connectivity on a mesoscopic scale. To this end, this paper uncovers dynamic spatiotemporal patterns emerging from electrically stimulated neu...
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PMID: 21622081
PDF is available here.
Abstract
Water ordering near a charged membrane surface is important for many biological processes such as binding of ligands to a membrane or transport of ions across it. In this work, the mean-field Poisson-Boltzmann theory for point-like ions, describing an electrolyte solution in contact...
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PMID: 21613667
PDF is available here.
Abstract
The paper presents the results of viscosity determinations on aqueous solutions of different mammalian serum albumins at a wide range of concentrations and at temperatures ranging from 278 K to 318 K. On the basis of these measurements and a modified Arrhenius equation, the functiona...
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PMID: 21613666
PDF is available here.
Abstract
We analyzed the possible relationship between the protein folding rates and the corresponding mRNA sequences. The content of guanine and cytosine (GC content) of palindromes in protein coding sequence was introduced as a new parameter and added in the Gromiha's model of predicting protein folding ra...
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PMID: 21613670
PDF is available here.
Abstract
We electronically measured the mean cell volume of rat glioma cells under three different experimental conditions, namely: at different osmolarities and constant NaCl concentration; at different NaCl concentrations and constant osmolarity and at different osmolarities caused by changes in NaCl conce...
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PMID: 21613671
PDF is available here.
Abstract
We report a theoretical study of second-harmonic generation (SHG) from the collagen fibrils which have a tilt angle Φ between their axes with the plane of the polarization angle α of the linearly polarized focused light. The effects of Φ as well as α on SHG emission have been investigated. Our r...
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PMID: 21613673
PDF is available here.
Abstract
We introduce the dimensionless parameter, called by us a Katchalsky number (Ka), modifies R(C) of membrane transport. The critical value of this number well describes a moment of transition from the state of diffusion into convective diffusion membrane transport....
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PMID: 21613674
PDF is available here.
Abstract
In recent decades the global health paradigm gained an increasing systemic characterization. The ecosystem health theory states that a healthy ecosystem, whether natural or artificial, significantly contributes to the good health status of the human population.
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PMID: 21842709
PDF is available here.
Abstract
a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher i...
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PMID: 21616956
PDF is available here.