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Surface Plasmon Resonance (0):
Recent article
Surface Plasmon Resonance
Abstract
We show that the properties of B. anthracis Mn-NrdF and Fe-NrdF are in general similar for interaction with NrdE and NrdI. Intriguingly, the enzyme activity of Mn-NrdF was approximately an order of magnitude higher than that of Fe-NrdF in the presence of the class Ib-specific physiological reductant...
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PMID: 21832039
PDF is available here.
PDF is available here.
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Abstract
We report that there is a biased usage of TCR Vβ6.7 chain among TCRs reactive to the immunodominant DQ2-α-II gliadin epitope. We isolated Vβ6.7 and DQ2-αII tetramer-positive CD4(+) T cells from peripheral blood of gluten-challenged celiac patients and sequenced the TCRs of a large number of sing...
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PMID: 21849672
PDF is available here.
PDF is available here.
Abstract
Healthy epithelial cells, in vivo, have the ability to synthesize gold nanoparticles when aqueous tetrachloroauric acid is made to react with human skin. Neither a reducing agent nor a protecting chemical is needed for this bio-synthesis method. The first indication of gold nanoparticle formation is...
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PMID: 21817787
PDF is available here.
PDF is available here.
Abstract
We show that the mouse iNKT TCR recognizes the complex β-linked Ag isoglobotrihexosylceramide (iGb3; Galα1-3-Galβ1-4-Glcβ1-1Cer) by forcing the proximal β-linked sugar of the trisaccharide head group to adopt the typical binding orientation of α-linked glycolipids. The squashed iGb3 orientatio...
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PMID: 21810611
PDF is available here.
PDF is available here.
Abstract
We report three-dimensional structures of individual SipD, SipD in fusion with the needle subunit PrgI, and of SipD:PrgI in complex with the bile salt, deoxycholate. Assembly of the complex involves major conformational changes in both SipD and PrgI. This rearrangement is mediated via a π bulge in...
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PMID: 21829362
PDF is available here.
PDF is available here.
Abstract
The data is presented concerning the implementation of nano-particles of aurum in the diagnostics of systemic lupus erythematosus. It is demonstrated that nano-particles sensibilized by deoxyribonucleoprotein are able to detect the specific antibodies--the known markers of systemic l...
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PMID: 21901893
PDF is available here.
PDF is available here.
Abstract
We investigate the light-triggered release of DNA from two types of nanoparticle substrates: Au nanoshells and Au nanorods. Both light-triggered and thermally induced release are distinctly observable from nanoshell-based complexes, with light-triggered release occurring at an ambient solution tempe...
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PMID: 21736347
PDF is available here.
PDF is available here.
Abstract
Hollow gold nanospheres (HGNs) were excited with ultrashort laser pulses, and the coherent vibrational response was examined using femtosecond time-resolved transient absorption. The results indicated that HGNs support an isotropic mode, resulting in periodic modulation of the surfac...
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PMID: 21714493
PDF is available here.
PDF is available here.
Abstract
We propose that the selected RNA aptamer is a potential cancer imaging agent by targeting malignant cells overexpressing the ErbB2 receptor....
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PMID: 21749294
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1814)9 2011
Abstract
We used biophysical and biochemical approaches to directly monitor small molecule binding to Gβγ. Surface plasmon resonance (SPR) analysis indicated that multiple compounds bound directly to Gβγ with affinities in the high nanomolar to low micromolar range but with surprisingly slow on and off r...
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PMID: 21621014
PDF is available here.
PDF is available here.
Abstract
We report a facile chemical synthesis of well-defined gold nanocrosses through anisotropic growth along both ⟨110⟩ and ⟨001⟩, whereas gold nanorods grow only along either ⟨110⟩ or ⟨001⟩. The multiple branching was achieved by breaking the face-centered-cubic lattice symmetry of gold t...
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PMID: 21563806
PDF is available here.
PDF is available here.
Abstract
We report a multicenter study to assess the potential of hybridoma and phage-display technologies in a coordinated large-scale antibody generation and validation effort. We produced over 1,000 antibodies targeting 20 SH2 domain proteins and evaluated them for potency and specificity by enzyme-linked...
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PMID: 21572409
PDF is available here.
PDF is available here.
Abstract
Detection of mercury at concentration levels down to parts-per-billion is a problem of fundamental and practical interest due to the high toxicity of the metal and its role in environmental pollution. The extensive research in this area has been focused primarily on specific sensing...
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PMID: 21395242
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1808)9 2011
Abstract
Multivalent protein binding plays an important role not only in biological recognition but also in biosensor preparation. Infrared reflection absorption spectroscopy and surface plasmon resonance techniques have been used to investigate concanavalin A (Con A) binding to binary monolayers composed of...
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PMID: 21640072
PDF is available here.
PDF is available here.
Abstract
We isolated a novel lectin from Carica papaya seeds, named C. papaya lectin (CPL). Purification of the lectin involved ammonium sulfate fractionation and DEAE anion exchange and repeated gel filtration chromatography. Inhibition of CPL causing hemagglutination on human erythrocytes showed that the l...
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PMID: 21405109
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1814)5 2011
Abstract
Crystal of Russell Viper venom phospholipase A(2) complexed with an isoquinoline alkaloid, berberine from a herbaceous plant Cardiospermum halicacabum, was prepared and its structure was solved by X-ray crystallography. The crystal diffracted up to 1.93Å and the structure solution clearly located th...
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PMID: 21420512
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1808)8 2011
Abstract
The interaction of antipsychotic drugs (AP) with lipids and the subsequent lipid reorganization on model membranes was assessed using a combination of several complementary biophysical approaches (calorimetry, plasmon resonance, fluorescence microscopy, X-ray diffraction and molecular modeling). The...
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PMID: 21377444
PDF is available here.
PDF is available here.
Abstract
We have identified two novel G-quadruplex ligands that reduce the transcription of a luciferase reporter driven from the G-quadruplex-containing c-KIT promoter. We have further shown that endogenous c-KIT expression in a human gastric carcinoma cell line is also reduced on treatment with these molec...
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PMID: 21294544
PDF is available here.
PDF is available here.
Abstract
Many biomolecules have specific binding properties in the nanostructure formation; they are attractive materials for nanotechnology. One such promising construction material for growing a well-defined nanostructure is deoxyribonucleic acid, due to its π-electron hydrophobic core and predictable reco...
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PMID: 21382609
PDF is available here.
PDF is available here.
Abstract
We show simultaneous binding of FH19 to C3b and FH20 to nonactivator surface glycosaminoglycans, and we show that both of these interactions are necessary for full binding of FH to C3b on nonactivator surfaces (i.e., for target discrimination). We also show that C3d could replace glycosaminoglycan b...
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PMID: 21285368
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1813)5 2011
Abstract
We discovered that a simple dimeric model does not fit with experimental data. A molecular model of the experimentally observed Bcl-2 homomeric complex has been developed. Accordingly, using a panel of mutants we identified in the loop a critical region for the process of Bcl-2 multimerisation. Our...
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PMID: 21320534
PDF is available here.
PDF is available here.
Abstract
We focus here on the question of initial adhesion, the mechanisms of which are still far from being fully understood. Recently, the frontier between microbiologists and physicists has become increasingly permeable, boosting implementation of new methodological approaches for better elucidating the i...
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PMID: 21557073
PDF is available here.
PDF is available here.
Abstract
We investigated the possible role of other viral capsid proteins on the FX/HSPG-mediated cellular uptake of HAdV5-based vectors. Using CAR- and CD46-negative CHO cells varying in HSPG expression, we confirmed that FX bound to serotype 5 hexon protein and to HAdV5 and HAdV5F35 virions via its Gla-dom...
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PMID: 21637339
PDF is available here.
PDF is available here.
Abstract
We have earlier shown that conditional folding of the GR AF1 is the key for its interactions with critical coactivator proteins. We hypothesize that binding of TBP to AF1 results in the structural rearrangement of the ID AF1 domain such that its surfaces become easily accessible for interaction with...
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PMID: 21760925
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1814)3 2011
Abstract
We consider the first of these interactions. (1) We confirm earlier observations, showing that the first two paired repeats (βIR1 with αIR21, and βIR2 with αRI20) at one end of the erythroid spectrin (αIβI) dimer are necessary and sufficient to unite the chains; (2) we resolve a conflict in pu...
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PMID: 21215336
PDF is available here.
PDF is available here.
Abstract
We mutated several residues located at the antigen-binding pocket to Ala, and kinetic analysis of the interactions between the mutant proteins and the antigen fragment was performed. The results indicate that some residues associated with the rigid antigen-binding pocket are structural hot-spots and...
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PMID: 21161086
PDF is available here.
PDF is available here.
Abstract
We used a novel biosensor-based surface plasmon resonance (SPR) technique for estimation of circulating COX-2 levels in 76 patients with oral cancer and 43 normal individuals. Antitumor activities of five COX-2 inhibitory peptides were evaluated using propidium iodide labeling and flow cytometry, al...
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PMID: 20213098
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe a novel series of 10 antibodies towards GPA, recognizing four extra- and intracellular peptide epitopes of this molecule (defined by epitope mapping) and one mixed peptide/carbohydrate epitope. All antibodies bind better to the desialylated than to the fully sialylated molecule, includin...
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PMID: 20727998
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (135)11 2010
Abstract
We have developed DNA aptamer sequences that selectively bind an N-glycosylated peptide fragment of vascular endothelial growth factor (VEGF). The selection method incorporates alternating positive- and counter-selection steps in free solution in order to obtain aptamers with both high affinity towa...
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PMID: 20820497
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (135)11 2010
Abstract
A method was developed for the synthesis of molecularly imprinted Au nanoparticle (NP) composites on electrodes by electrochemical means. The resulting composites include specific recognition sites for mono- or disaccharides. The method is based on the formation of a boronate complex between the res...
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PMID: 20830445
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (135)11 2010
Abstract
Ever since the advent of surface plasmon resonance (SPR) and SPR imaging (SPRi) in the early 1990s, their use in biomolecular interaction analysis (BIA) has expanded phenomenally. An important research area in SPR sensor development is the design of novel and effective interfaces that allow for the...
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PMID: 20830330
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (135)11 2010
Abstract
We report a molecular recognition between adenosine and its aptamer, which leads to the formation of a four-stranded tetraplex structures (G-quartet) of the aptamer. It is found that the formed G-quartet could induce the side-by-side self-assembly of gold nanorods (AuNRs) owing to the electrostatic...
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PMID: 20830327
PDF is available here.
PDF is available here.
Abstract
We aimed to investigate the potential of mannose-containing glycopolymers to interact with human DC-SIGN and the ability of these glycopolymers to inhibit the interactions between DC-SIGN and the HIV envelope glycoprotein gp120. We used a library of glycopolymers that are prepared via combination of...
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PMID: 20932025
PDF is available here.
PDF is available here.
Abstract
MG7-Ag is a kind of gastric cancer-specific tumor-associated antigen and has been investigated to serve as a marker of gastric cancer for early diagnosis.
Surface plasmon resonance (SPR) sensor was used for the detection of MG7-Ag in the sera of gastric cancer patients to develop an innovative, simp...
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PMID: 20887942
PDF is available here.
PDF is available here.
Biomedical Materials (5)5 2010
Abstract
We synthesized a water-insoluble phospholipid polymer bearing a phenylboronic acid moiety (PMBV), which induces cell adhesion through a specific interaction with the glycoprotein, fibronectin. Surface plasmon resonance analysis revealed that fibronectin was adsorbed on the PMBV surface. When fibrobl...
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PMID: 20876952
PDF is available here.
PDF is available here.
Optics Express (18)20 2010
Abstract
We have designed various two-dimensional refractive dielectric optical elements for surface plasmons (SP) and characterized their capacity to route SP, using near- or far-field techniques. We first present basic devices analogous to usual optical components and the associated challenges for SP optic...
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PMID: 20940955
PDF is available here.
PDF is available here.
Optics Express (18)20 2010
Abstract
Two-dimensional arrays of silver nanocylinders fabricated by electron-beam lithography are used to demonstrate plasmon-enhanced near-green light emission from nitride semiconductor quantum wells. Several arrays with different nanoparticle dimensions are employed, designed to yield collective plasmon...
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PMID: 20941028
PDF is available here.
PDF is available here.
Optics Express (18)20 2010
Abstract
We experimentally demonstrate focusing and guiding electromagnetic (EM) waves in a designer surface plasmonic waveguide with deep subwavelength mode cross section. Our experiments show that a metal grating with suitable parameters, functioning as a designer surface plasmonic waveguide, can support d...
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PMID: 20941046
PDF is available here.
PDF is available here.
Nanotechnology (21)35 2010
Abstract
We demonstrated enhanced localized surface plasmon resonance (SPR) biosensing based on subwavelength gold nanoarrays built on a thin gold film. Arrays of nanogratings (1D) and nanoholes (2D) with a period of 200 nm were fabricated by electron-beam lithography and used for the detection of avian infl...
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PMID: 20693616
PDF is available here.
PDF is available here.
Journal of Dairy Science (93)9 2010
Abstract
We proposed an original and complete analytical package for the examination of the putative effect of filtration at both macroscopic and molecular levels. We then investigated the pertinence of this analytical package during ultrafiltration (UF) of globular milk proteins in both dead-end and crossfl...
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PMID: 20723664
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
We show that long-range surface plasmons (LRSPs) are supported in a physically asymmetric thin film structure, consisting of a low refractive index medium on a metal slab, supported by a high refractive index dielectric layer (membrane) over air, as a suspended waveguide. For design purposes, an ana...
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PMID: 20940795
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
We observe the appearance of multiple dipole surface plasmon resonances in spherical Ag nanoparticles when embedded in an organic semiconductor that exhibits a highly dispersive permittivity. Comparing the absorption spectra of thin-films with and without Ag nanoparticles reveals the presence of two...
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PMID: 20940797
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
This paper reports the design analysis of a microfabricatable mid-infrared (mid-IR) surface plasmon resonance (SPR) sensor platform. The proposed platform has periodic heavily doped profiles implanted into intrinsic silicon and a thin gold layer deposited on top, making a physically flat grating SPR...
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PMID: 20940835
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
We demonstrate an optical gain of ~200 cm(-1) for the mode under consideration, which corresponds to ~32% compensation of SPP loss....
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PMID: 20940755
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
We investigate the propagation properties of terahertz plasmon of a metallic nanowire with sub-skin-depth diameter. By taking the small radius and the huge relative permittivity into account, we establish an approximate analytical description for this kind of surface plasmon. It is shown that the ma...
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PMID: 20940747
PDF is available here.
PDF is available here.
Abstract
In this study, an interface embedded in situ gold nanoparticles (AuNPs) and biotin in chitosan hydrogel was constructed by one-step electrochemical deposition in solution containing tetrachloroauric (III) acid, biotin and chitosan. This deposited interface acts as biosensing platform...
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PMID: 21133092
PDF is available here.
PDF is available here.
Abstract
We used molecular simulations to generate the first predicted structure(s) of synthetic knobs in solution before fibrin hole engagement. Combining surface plasmon resonance (SPR), we explored the role of structural and electrostatic properties of knob "A" mimics in regulating knob:hole binding kinet...
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PMID: 20484082
PDF is available here.
PDF is available here.
Abstract
Nanowires are important potential candidates for the realization of the next generation of sensors. They offer many advantages such as high surface-to-volume ratios, Debye lengths comparable to the target molecule, minimum power consumption, and they can be relatively easily incorporated into microe...
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PMID: 20712030
PDF is available here.
PDF is available here.
Abstract
This paper describes three-dimensional (3D) nanohole arrays whose high optical transmission is mediated more by localized surface plasmon (LSP) excitations than by surface plasmon polaritons (SPPs). First, LSPs on 3D hole arrays lead to optical transmission an order of magnitude high...
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PMID: 20698633
PDF is available here.
PDF is available here.
Abstract
We describe a 21-residue peptide tag (designated as TARGET tag) and its use for rapid stable cell line development and purification. The ability of the anti-tag antibody P20.1 to withstand repetitive regeneration cycles has enabled the development of a sensitive surface plasmon resonance-based scree...
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PMID: 20566373
PDF is available here.
PDF is available here.
Dental Materials Journal (29)4 2010
Abstract
Hydroxyapatite formation was examined at the surface of self-assembled monolayers (SAMs) modified with four functional groups, -COOH, -NH(2), -CH(3), and -OH. For COOH-SAM and NH(2)-SAM, scanning electron spectroscopic observation showed that flake-like sheet crystals covered the whole wafer and sma...
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PMID: 20657151
PDF is available here.
PDF is available here.
Abstract
We demonstrated that A3G interacted with the HBV core protein (HBc) directly in co-transfected HepG2 cells using the fluorescence resonance energy transfer (FRET) approach. In addition, we further found that this interaction did not require other factors in vitro using surface plasmon resonance (SPR...
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PMID: 20510315
PDF is available here.
PDF is available here.
Abstract
We investigate and compare three different strategies to immobilize rhodopsin, a prototypical G-protein coupled receptor on a sensor chip surface using antibodies and a lectin for receptor capturing. By further probing of different experimental conditions (pH, detergent type) we identified the optim...
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PMID: 20544180
PDF is available here.
PDF is available here.
Analytical Biochemistry (405)1 2010
Abstract
The effect of human serum albumin (HSA) on an immunokinetic assay for an antibody to bovine serum albumin has been determined in model serum solutions with HSA concentrations in the range 0 to 450 microM (0-30 mgml(-1)). The assay is performed on two plasmon-based detection platforms: a continuous g...
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PMID: 20501319
PDF is available here.
PDF is available here.
Applied Optics (49)22 2010
Abstract
We show that a broadband surface plasmon can be excited in a thin metal film. A train of two plasmons can be excited at conditions near the condition of broadband surface plasmon excitation. Also, a method for independent multichannel checks of biochips by wavelength addressing is proposed.
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PMID: 20676187
PDF is available here.
PDF is available here.
Analyst (Cambridge UK) (135)8 2010
Abstract
One of the key issues to develop biosensing platforms concerns the processes involved in enzyme immobilization on surfaces. The understanding of their fundamentals is crucial to obtain stable and catalytically active protein layers for developing successful biosensing devices. In this respect, the a...
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PMID: 20552112
PDF is available here.
PDF is available here.
Nanotechnology (21)29 2010
Abstract
Preparation of a high-concentration Au nanoring (NR) water solution and its applications to the enhancement of image contrast in optical coherence tomography (OCT) and the generation of the photothermal effect in a bio-sample through localized surface plasmon (LSP) resonance are demonstrated. Au NRs...
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PMID: 20601768
PDF is available here.
PDF is available here.
Abstract
We utilized surface plasmon resonance to measure binding affinities between all combinations of alternatively spliced beta-NRX 1-3 and NL 1-3 ectodomains. Binding was observed for all beta-NRX/NL pairs. The presence of the NL1 B splice insertion lowers beta-NRX binding affinity by approximately 2-fo...
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PMID: 20624592
PDF is available here.
PDF is available here.
Abstract
A simple biosensing strategy for the diagnosis of patients with hepatitis B virus (HBV) was developed. This study can be divided into two themes, both of which utilized gold-binding polypeptide (GBP) fusion proteins: HBV surface antigen PreS2 (HBsAg) detection with GBP-fused single chain antibody (G...
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PMID: 20602973
PDF is available here.
PDF is available here.