Abstract
We show that long-range surface plasmons (LRSPs) are supported in a physically asymmetric thin film structure, consisting of a low refractive index medium on a metal slab, supported by a high refractive index dielectric layer (membrane) over air, as a suspended waveguide. For design purposes, an ana...
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PMID: 20940795
PDF is available here.
Abstract
We propose a platform for label-free optical biosensors based on applying the analyte onto a surface-functionalized photonic crystal slab and performing a transmission measurement with two crossed polarization filters. This dark-field approach allows for efficient background suppression as only the...
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PMID: 20940807
PDF is available here.
Abstract
We experimentally study the dependence of thin-film detection sensitivity on the optical geometrical parameters of tubes, different thicknesses and tube wall refractive indices, and on different resonant frequencies. A polypropylene hollow-tube with optimized sensitivity of 0.003 mm/μm is used to s...
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PMID: 20940830
PDF is available here.
Abstract
We theoretically investigate coupled Fano structures which combine the characteristics of both directly coupled Fabry-Perot cavities (DCFPC) and a side-coupled integrated spaced sequence of resonators (SCISSOR). Asymmetric and symmetric Fano resonances in a single and doubly-coupled Fano unit are an...
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PMID: 20940775
PDF is available here.
Abstract
Subwavelength InGaAs/AlInAs microdisk lasers are demonstrated under continuous-wave optical pumping at a heat-sink temperature of 45 K. A 1.49 µm diameter, 209 nm thick microdisk lases in single-mode at a wavelength of 1.53 µm, which is identified as the whispering-gallery mode with the first radi...
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PMID: 20940820
PDF is available here.
Abstract
This paper reports the design analysis of a microfabricatable mid-infrared (mid-IR) surface plasmon resonance (SPR) sensor platform. The proposed platform has periodic heavily doped profiles implanted into intrinsic silicon and a thin gold layer deposited on top, making a physically flat grating SPR...
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PMID: 20940835
PDF is available here.
Abstract
We have observed resonant terahertz transmission peaks in samples comprising perforated periodic hole array in a metal film, covered with a high dielectric substrate. These resonant transmissions arise from the interplay between waveguide modes in dielectric substrate and the periodic hole array in...
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PMID: 20940748
PDF is available here.
Abstract
We demonstrate an optical gain of ~200 cm(-1) for the mode under consideration, which corresponds to ~32% compensation of SPP loss....
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PMID: 20940755
PDF is available here.
Abstract
DNA piezoelectric biosensors have become a promising tool in molecular medicine since they do not require any label or staining. Here, a DNA piezoelectric biosensor based on a quartz crystal microbalance (QCM) was created to identify abnormal genes causing α-thalassemia 1 (SEA deletion).
The functi...
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PMID: 20578968
PDF is available here.
Abstract
A chiral, biocompatible, conducting material comprising collagen I, silica gel and ferrocene was found to modify and invert, the chiral selectivity of D-glucose oxidase and L-lactate oxidase. This result may have implications as collagen matrices are widely used in drug delivery, biosensing and tiss...
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PMID: 20664851
PDF is available here.
Abstract
We report a novel aptamer-based capacitive label-free biosensor for monitoring transducing aptamer-protein recognition events, based on charge distribution under the applied frequency by non-Faradaic impedance spectroscopy (NFIS). This approach to capacitive biosensors is reported for the first time...
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PMID: 20648264
PDF is available here.
Abstract
We propose explanations for the specific observed differences based on differential insulin insufficiency/resistance and mitochondrial dysfunction in T1DM versus T2DM.
© 2010 Diabetes Technology Society....
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PMID: 20920426
PDF is available here.
Abstract
In this study, an interface embedded in situ gold nanoparticles (AuNPs) and biotin in chitosan hydrogel was constructed by one-step electrochemical deposition in solution containing tetrachloroauric (III) acid, biotin and chitosan. This deposited interface acts as biosensing platform...
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PMID: 21133092
PDF is available here.
Abstract
Acetylcholinesterase (AChE) activity may be useful biomarker for detecting of organophosphate pesticides (OP). Thus a sensitive biosensor for quantitative determination of OP based on AChE biomonitoring was developed. Multi-walled carbon nanotube (MWCNT)/polyaniline (PANI) composite...
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PMID: 21133088
PDF is available here.
Abstract
We utilized these transgenic mice to determine the role of IL-1B in glucose sensor function in vivo.
To investigate the role of IL-1B in glucose sensor function in vivo, we compared glucose sensor function in trans-genic mice that (1) overexpressed IL-1RA [B6.Cg-Tg(II1rn)1Dih/J] and...
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PMID: 20920427
PDF is available here.
Abstract
The objective of this work was to determine the clinical accuracy of GlucoMen®Day, a new microdialysis-based continuous glucose monitoring system (CGMS) from A. Menarini Diagnostics (Florence, Italy). Accuracy evaluation was performed using continuous glucose-error grid analysis (CG...
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PMID: 20920438
PDF is available here.
Abstract
We review these findings along with arguments that continuous glucose monitoring (CGM) devices used to measure ISF delay contribute to the variability. We consider the impact of the ISF delay and review approaches to correct for it, including strategies pursued by the manufacturers of these devices....
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PMID: 20920428
PDF is available here.
Abstract
A biocompatible post-polymerization functionalization reaction takes advantage of a polymer's structural motif for the controllable attachment of biotin as a model biosensor that responds to streptavidin.
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PMID: 20596563
PDF is available here.
Abstract
A simple and sensitive immunosensor for the detection of cancer biomarker prostate specific antigen (PSA) has been developed. Around the percolation threshold of the graphene film, the conductivity of the graphene film varies significantly with the surface adsorption of molecules, which can be used...
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PMID: 20585690
PDF is available here.
Abstract
Nanowires are important potential candidates for the realization of the next generation of sensors. They offer many advantages such as high surface-to-volume ratios, Debye lengths comparable to the target molecule, minimum power consumption, and they can be relatively easily incorporated into microe...
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PMID: 20712030
PDF is available here.
D-X Xu,
M Vachon,
A Densmore,
R Ma,
A Delâge,
S Janz,
J Lapointe,
Y Li,
G Lopinski,
D Zhang,
Q Y Liu,
P Cheben and
J H Schmid
Abstract
We report a silicon-on-insulator ring resonator biosensor array with one output port, using wavelength division multiplexing as the addressing scheme. With the use of on-chip referencing for environmental drift cancellation, simultaneous monitoring of multiplexed molecular bindings is demonstrated,...
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PMID: 20717452
PDF is available here.
Abstract
We found that SOB biosensor can detect toxic chemicals, such as heavy metals and CN-, in the 5-2000ppb range. One bacterium was isolated from an SOB biosensor and the 16S rRNA gene of the bacterial strain has 99% and 96% sequence similarity to Acidithiobacillus sp. ORCS6 and Acidithiobacillus caldus...
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PMID: 20580751
PDF is available here.
Abstract
We describe the use of a microfluidic device to micropattern cells in a microchannel and investigated the behavior of these cells under a concentration gradient. The microfluidic device consisted of 3 parts: a branched channel for generating a stable concentration gradient, a main channel for cultur...
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PMID: 20547384
PDF is available here.
Abstract
I enzyme, with fish sperm double stranded deoxyribonucleic acid (dsDNA) and synthetic short oligonucleotides were studied electrochemically based on the oxidation signals of guanine and CPT-11 by using differential pulse voltammetry (DPV) and cyclic voltammetry (CV) at pencil graphite electrode (PGE...
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PMID: 20426745
PDF is available here.