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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Physical Conditioning, Animal (0):
Recent article
Physical Conditioning, Animal
Abstract
We studied the effect of exercise training on islet and β-cell morphology and plasma insulin and glucose, following an intraperitoneal glucose tolerance test (IPGTT) in juvenile and adult male Wistar-Kyoto rats born small. Bilateral uterine vessel ligation performed on day 18 of pregnancy resulted...
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PMID: 21810930
PDF is available here.
PDF is available here.
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Abstract
Glucagon is a primary regulator of hepatic glucose production (HGP) in vivo during fasting, exercise and hypoglycaemia. Glucagon also plays a role in limiting hepatic glucose uptake and producing the hyperglycaemic phenotype associated with insulin deficiency and insulin resistance. In response to a...
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PMID: 21824265
PDF is available here.
PDF is available here.
Journal of Neuroscience (31)32 2011
Abstract
We have previously found that healthy aged rats are more likely to suffer profound memory impairments following a severe bacterial infection than are younger adult rats. Such a peripheral challenge is capable of producing a neuroinflammatory response, and in the aged brain this response is exaggerat...
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PMID: 21832188
PDF is available here.
PDF is available here.
Proteomics (11)16 2011
Abstract
We analysed hearts of HCRs and LCRs from generation 22 of selection using DIGE and identified proteins from MS database searches. The running capacity of HCRs was six-fold greater than LCRs. DIGE resolved 957 spots and proteins were unambiguously identified in 369 spots. Protein expression profiling...
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PMID: 21751351
PDF is available here.
PDF is available here.
Abstract
Objective-To compare the toxic effects of a Delphinium occidentale chemotype containing N-(methylsuccinimido) anthranoyllycoctonine (MSAL)-type alkaloids and a D occidentale chemotype lacking MSAL-type alkaloids in mice and cattle. Animals-225 male Swiss Webster mice and 11 Black Angus steers. Proced...
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PMID: 21529225
PDF is available here.
PDF is available here.
Abstract
12 European shorthair cats (6 males and 6 females; age range, 2 months to 3 years) from 1 household were evaluated for clinical signs of recurrent and progressive muscle spasticity. Genetic relationships among the cats were suspected but were not known.
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PMID: 21492046
PDF is available here.
PDF is available here.
Journal of Physiology (589)Pt 3 2011
Abstract
Journal of Physiology (589)Pt 3 2011
Abstract
Abstract
These results suggest that oxidative stress caused by acute exercise induces an adaptive response responsible for the radioprotective effects of exercise training....
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PMID: 21326381
PDF is available here.
PDF is available here.
Abstract
Cranial cruciate ligament disease (CCLD) is the most common cause of hindlimb lameness in the dog, being associated with and eventually leading to stifle osteoarthritis. Canine cranial cruciate ligament disease is a gradual degeneration of the ligament extracellular matrix (ECM) leading to ligament r...
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PMID: 21243176
PDF is available here.
PDF is available here.
Abstract
We used the two months tail suspension model to simulate microgravity and investigated the simulated microgravity on the renal morphological damages and related molecular mechanisms. The microscopic examination of tissue structure and ultrastructure was carried out for histopathological changes of r...
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PMID: 21625440
PDF is available here.
PDF is available here.
Abstract
We showed that C/EBPβ was downregulated with exercise, whereas the expression of CITED4 was increased. Reduction of C/EBPβ in vitro and in vivo resulted in a phenocopy of endurance exercise with cardiomyocyte hypertrophy and proliferation. This proliferation was mediated, at least in part, by the...
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PMID: 21183071
PDF is available here.
PDF is available here.
Abstract
Limited information exists about the physiological training-induced changes in electrolyte balance of horses competing in long distance endurance races.
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PMID: 21058989
PDF is available here.
PDF is available here.
Abstract
The inflammatory and neuroendocrine response to endurance exercise and relationship of these parameters to performance is not well documented in horses. HYPOTHESES OR OBJECTIVES: Evidence of systemic inflammation is associated with poor performance in horses competing in endurance events.
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PMID: 21058993
PDF is available here.
PDF is available here.
Abstract
Head and neck positions (HNP) in sport horses are under debate in the equine community, as they could interfere with equine welfare. HNPs have not been quantified objectively and no information is available on their head and neck loading.
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PMID: 21059042
PDF is available here.
PDF is available here.
Abstract
Sildenafil, a phosphodiesterase-5 inhibitor vasodilator, increases cGMP concentrations by inhibiting enzymatic degradation. Marketed to treat erectile dysfunction in men, it also reduces pulmonary arterial pressure (PAP). Because it reduces PAP, sildenafil may enhance performance and/or prevent exerc...
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PMID: 21059068
PDF is available here.
PDF is available here.
Abstract
In exercising horses, up to 50% of blood lactate is taken up into red blood cells (RBCs). Lactate transporter proteins MCT1, MCT2 and CD147 (an ancillary protein for MCT1) are expressed in the equine RBC membrane. In Standardbreds (SB), lactate transport activity is bimodally distributed and correlat...
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PMID: 21059000
PDF is available here.
PDF is available here.
Abstract
Recurrent exertional rhabdomyolysis (RER) occurs in fit, nervous Thoroughbreds fed high nonstructural carbohydrate (NSC) diets. Clinical signs are diminished by feeding low NSC, high fat diets; however, the mechanism is unclear.
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PMID: 21059025
PDF is available here.
PDF is available here.
Abstract
Locomotion requires successful negotiation of different terrains, but we currently know little of how the musculoskeletal system adapts to cope with positive and negative slopes.
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PMID: 21059038
PDF is available here.
PDF is available here.
Pediatric Research (68)5 2010
Abstract
We previously reported that exposure of muscles in growing rats to IL-6 results in decreased muscle growth apparently because of a state of resistance to growth factors such IGF-I and that running exercise could ameliorate this growth defect. Herein, we hypothesized that increased activity, for a br...
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PMID: 20657345
PDF is available here.
PDF is available here.
British Journal of Nutrition (104)10 2010
Abstract
During exercise, ammonia levels are related to the appearance of both central and peripheral fatigue. Therefore, controlling the increase in ammonia levels is an important strategy in ameliorating the metabolic response to exercise and in improving athletic performance. Free amino acids can be used...
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PMID: 20594391
PDF is available here.
PDF is available here.
Abstract
High-fat feeding activates components of the pro-inflammatory pathway and increases co-immunoprecipitation of suppressor of cytokine signalling (SOCS)-3 with both the insulin receptor (IR)-β subunit and IRS-1, which together contribute to keeping PI-3 kinase from being fully activated. However, whe...
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PMID: 20596724
PDF is available here.
PDF is available here.
Abstract
Although beach training is commonly used in horses, limb loading on beach sand has never been investigated. A dynamometric horseshoe (DHS) is well adapted for this purpose.
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PMID: 21059058
PDF is available here.
PDF is available here.
Abstract
During the past 20 years, treadmill exercise testing has played an important role in both the study of equine exercise physiology and the investigation of poor athletic performance. However, it has been suggested that some trainers and veterinarians may be reluctant to refer horses for treadmill exer...
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PMID: 21058985
PDF is available here.
PDF is available here.
Anesthesiology (113)5 2010
Abstract
Sleep apnea, hypertension, atherosclerosis, and obesity are features of metabolic syndrome associated with decreased restorative sleep and increased pain. These traits are relevant for anesthesiology because they confer increased risks of a negative anesthetic outcome. This study tested the one-tail...
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PMID: 20938334
PDF is available here.
PDF is available here.
Abstract
We were interested in identifying alternative mechanisms that could regulate PDK4 mRNA expression in white adipose tissue. In this regard we hypothesized that exercise, fasting, and epinephrine would increase PDK4 mRNA levels in rat epididymal adipose tissue. We further postulated that the p38 mitog...
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PMID: 20739620
PDF is available here.
PDF is available here.
Circulation (122)12 2010
Abstract
Neuroscience Letters (481)3 2010
Abstract
We determined the effects of treadmill exercise on survival of Purkinje neurons and on a population of reactive astrocytes in the gyrus of lobules VIII and IX of the cerebellum after TBI. The rats were divided into four groups: the sham-operation group, the sham-operation with exercise group, the TB...
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PMID: 20603186
PDF is available here.
PDF is available here.
Journal of Proteomics (73)10 2010
Abstract
Exercise has been shown to improve function of the left ventricle (LV) following myocardial infarction (MI). The mechanisms to explain this benefit have not been fully delineated, but may involve improved mechanics resulting in unloading effects and increased endothelial nitric oxide...
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PMID: 20601275
PDF is available here.
PDF is available here.
Abstract
We test the hypothesis that exercise training can protect the aging liver against alcohol-induced oxidative damage. Two different age groups of Wistar albino rats (3 months young, n=24; 18 months old, n=24) were evenly divided into four groups: control (Con), exercise trained (Tr, 23 m/min 30 min/da...
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PMID: 20705416
PDF is available here.
PDF is available here.
Hormones and Behavior (58)3 2010
Abstract
Muscle & Nerve (42)2 2010
Abstract
Malignant hyperthermia (MH) episodes may occur upon exposure to halogenated anesthetics, during resistance and endurance exercise, and in response to thermal stress. The purpose of this study was to investigate the effects of prior eccentric and concentric (i.e., wheel running) exercise on the therm...
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PMID: 20544946
PDF is available here.
PDF is available here.
Abstract
We identified 77 different proteins mostly from the oxidative phosphorylation and mitochondrial metabolism. Sedentary mice presented a significant loss of ETC functionality in opposition to active mice. Although some proteins were found damaged in both A and S mice, damage to ETC proteins was more e...
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PMID: 20513666
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to evaluate if spontaneous (nonforced active) exercise and age (maturation process) alter the biomechanical and biochemical properties of superficial digital flexor tendon. Chickens aged 1, 5, and 8 months were divided into two groups: caged and penned. The caged group was...
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PMID: 20175711
PDF is available here.
PDF is available here.
Abstract
Our results show that central fatigue due to hyperthermia and increased body heating rate induced by central Ang II AT1 receptor blockade in exercising rats is related with higher 5-HT content in the preoptic area and hypothalamus as well as with decreased levels of this neurotransmitter in the hipp...
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PMID: 20068491
PDF is available here.
PDF is available here.
Abstract
Voluntary wheel running increased cholesterol turnover in healthy mice owing to an increased fecal bile acid excretion and a decreased intestinal cholesterol absorption. Enhanced cholesterol turnover may contribute to the established reduction of cardiovascular risk induced by regular exercise....
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PMID: 20139791
PDF is available here.
PDF is available here.
Behavioural Brain Research (211)2 2010
Abstract
Chronic stress impairs cognitive function and hippocampal neurogenesis. This impairment is attributed to increases in oxidative stress, which result in the accumulation of lipid peroxide. On the other hand, voluntary exercise enhances cognitive function, hippocampal neurogenesis, and antioxidant cap...
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PMID: 20307585
PDF is available here.
PDF is available here.
Brain research (1345) 2010
Abstract
We evaluated the expression of both Egr-1 and SP in the sacrolumbar area of the spinal cord after locomotor training in adult rats. Increased neuronal Egr-1 expression was found in the spinal cord sections in rats that underwent locomotor training, especially in laminae IV and X across L3-S4 levels...
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PMID: 20546710
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)29 2010
Abstract
We wanted to understand the significance of induction of ERRgamma expression in skeletal muscle by exercise. Muscle-specific VP16ERRgamma transgenic mice demonstrated an increase in exercise capacity, mitochondrial enzyme activity, and enlarged mitochondria despite lower muscle weights. Furthermore,...
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PMID: 20418374
PDF is available here.
PDF is available here.
Abstract
Fractured PSBs and their contralateral intact PSBs had more compacted trabecular bone than did control PSBs. Focal repair or remodeling was evident in the palmar aspect of many fractured and contralateral intact PSBs. Fracture coincided with microstructural features and propagated from the flexor to...
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PMID: 20594077
PDF is available here.
PDF is available here.
Abstract
Osteochondral injury affected concentrations of CPII, CTX II, C1,2C, and C2C in SF, serum, or both, compared with concentrations in healthy adult horses. Compared with adult horses, yearling horses had increased SF or serum concentrations of degradative biomarkers (CTX II, C1,2C, and C2C). Concentra...
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PMID: 20594075
PDF is available here.
PDF is available here.
Abstract
We investigated whether the administration of rTMS together with paroxetine would enhance its effects on the beta-adrenergic system of the rat. We compared our results with the effects of electroconvulsive shock therapy (ECS). The experiment was performed for 12 d on male Wistar rats that received a...
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PMID: 19698191
PDF is available here.
PDF is available here.
Carcinogenesis (31)7 2010
Abstract
Emerging evidence indicates that intrinsic differences and induced changes in aerobic capacity are probably to play a critical role in the development of chronic diseases like cancer. This study was initiated: (i) to determine how citrate synthase activity, which is routinely used as a marker of aer...
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PMID: 20299525
PDF is available here.
PDF is available here.
Abstract
The aim of the present study is to examine how melatonin supplementation affects plasma glucose and liver glycogen levels in rats subjected to acute swimming exercise. Sprague-Dawley species thirty adult male rats were allocated to 3 groups with equal number of animals: general control group which w...
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PMID: 20566433
PDF is available here.
PDF is available here.
Abstract
Abstract
Pulmonary artery to left atrial TAL use will not decrease CO during rest or mild exercise but may not allow more vigorous exercise.
Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved....
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PMID: 20609788
PDF is available here.
PDF is available here.
Abstract
Effective therapy to reduce skeletal muscle injury associated with severe or eccentric exercise is needed. The purpose of this study was to determine whether adenosine receptor stimulation can mediate protection from eccentric exercise-induced muscle injury. Downhill treadmill exercise (-15 degrees...
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PMID: 20427727
PDF is available here.
PDF is available here.
Abstract
Inhibition of the commissural nucleus of the solitary tract (commNTS) induces a fall in sympathetic nerve activity and blood pressure in spontaneously hypertensive rats (SHR), which suggests that this subnucleus of the NTS is a source of sympathoexcitation. Exercise training reduces sympathetic acti...
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PMID: 20410480
PDF is available here.
PDF is available here.
Abstract
We determined the effects of voluntary wheel running on the hypothalamic-pituitary-adrenal (HPA) axis, and the peripheral determinants of glucocorticoids action, in male Zucker diabetic fatty (ZDF) rats. Six-week-old euglycemic ZDF rats were divided into Basal, Sedentary, and Exercise groups (n = 8-...
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PMID: 20393161
PDF is available here.
PDF is available here.
Abstract
The cell numbers in the anulus fibrosus (AF) increased by 25% (P < 0.05) after 3 weeks of exercise. Collagen-2 and Sox-9 mRNA were strongly expressed in the nucleus pulposus (NP) samples of the running group, but weakly expressed in the controls. An increase in collagen-II, aggrecan, and Sox-9 prote...
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PMID: 20592578
PDF is available here.
PDF is available here.
Hormones and Behavior (58)4 2010
Abstract
Based on cortisol release, a variety of situations to which domestic horses are exposed have been classified as stressors but studies on the stress during equestrian training are limited. In the present study, Warmblood stallions (n=9) and mares (n=7) were followed through a 9 respective 12-week ini...
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PMID: 20600048
PDF is available here.
PDF is available here.
Journal of Physiology (588)Pt 11 2010
Abstract
Abstract
I (soleus, r=-0.93; EDL, r=-0.90; p<0.05) and IIa (EDL, r=-0.52, p<0.05) muscle fibers. These findings indicate that changes in IMCL content but not UCP3 content are implicated in short-term effects of cafeteria-style diet and exercise training on muscular insulin sensitivity in rats....
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PMID: 20428795
PDF is available here.
PDF is available here.
Neurological Research (32)5 2010
Abstract
This study revealed that pre-ischemic exercise in rats improved cerebral blood flow during reperfusion, suggesting that exercise provides neuroprotection by partially ameliorating the 'no reflow' phenomenon in stroke....
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PMID: 20092679
PDF is available here.
PDF is available here.
Abstract
We have analyzed sedentary and exercised animals to examine the effects of activity on behaviour (spatial memory and anxiety--as measured by a fear/exploration conflict test), as well as on adult hippocampal neurogenesis (a well-known form of neural plasticity). We have found that the difference in...
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PMID: 20206269
PDF is available here.
PDF is available here.
Neuroscience Letters (476)2 2010
Abstract
We tried to investigate the role of swimming exercise in combined stress and whether its biological mechanism was related to the HSP70 and iNOS in hippocampus and prefrontal cortex. 32 Wistar rats were enrolled and divided into four groups: control, CUMS, labetalol and exercise. After the animal mod...
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PMID: 20398736
PDF is available here.
PDF is available here.
Neuroscience (167)4 2010
Abstract
This study examined whether regular exercise training, at a level that would be recommended for middle-aged people interested in improving fitness could lead to improved cognitive performance and increased blood flow to the brain in another primate species. Adult female cynomolgus monkeys were train...
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PMID: 20211699
PDF is available here.
PDF is available here.
Abstract
To investigate the effect of exercise on the expressions of phosphatidylinositol 3 kinase (PI3K) and protein kinase B (PKB) phosphorylation, protein and glucose transport proteins (GLUT4) at both the protein and mRNA levels in the skeletal muscles of type 2 diabetic rats....
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PMID: 20584641
PDF is available here.
PDF is available here.
Experimental Physiology (95)5 2010
Abstract
We concluded that a single bout of aerobic exercise acutely improves insulin- and IGF-1-mediated vasorelaxation in an endothelium-dependent manner in hypertensive rats....
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PMID: 20139168
PDF is available here.
PDF is available here.
Neurological Research (32)4 2010
Abstract
Our results suggested that physical exercise plays an important role in the recovery of damaged neural function and induction of angiogenesis after cerebral infarction in rats....
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PMID: 20483007
PDF is available here.
PDF is available here.