Abstract
We measured the effect of variations in scaffold stiffness on the expression of extracellular matrix molecules specific to the NP (proteoglycans and collagen) by native NP cells. We prepared sample discs of different concentrations of alginate (1%-6%) by two different methods, diffusion and in situ...
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PMID: 21783128
PDF is available here.
Abstract
We discovered that, during rapid swimming of Giardia trophozoites, undulations of the caudal region contributed to forward propulsion combined with the beating of the flagella pairs. It was also discovered, in contrast to previous studies with 10 times slower image sampling technique, that the anter...
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PMID: 21808023
PDF is available here.
Abstract
Low seeding efficiency and poor cell retention under flow-induced shear stress limit the effectiveness of in vitro endothelialization strategies for small-diameter vascular grafts. Primary-amine-rich plasma-polymerized coatings (PPE:N) deposited using low- and atmospheric-pressure pl...
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PMID: 21591258
PDF is available here.
Abstract
The superficial tangential zone (STZ) plays a significant role in normal articular cartilage's ability to support loads and retain fluids. To date, tissue engineering efforts have not replicated normal STZ function in cartilage repairs. This finite element study examined the STZ's ro...
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PMID: 20700624
PDF is available here.
Abstract
The control of the mechanical stimuli transmitted to the cells is critical for the design of functional scaffolds for tissue engineering. The objective of this study was to investigate the dynamics of the mechanical stimuli transmitted to the cells during tissue differentiation in an...
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PMID: 20865437
PDF is available here.
Abstract
We have designed and produced a modular, recombinant resilin-like polypeptide bearing both mechanically active and biologically active domains to create novel biomaterial microenvironments for engineering mechanically active tissues such as blood vessels, cardiovascular tissues, and vocal folds. Pre...
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PMID: 21553895
PDF is available here.
Abstract
The paper evaluates the liberation of alaptide from gels through various types of permeable membranes. The gels were prepared on the basis of three different polymers (3% chitosan; 2.5% hydroxypropyl cellulose; 3% hydroxyethyl cellulose) in different concentrations with additions of...
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PMID: 21838143
PDF is available here.
Abstract
We present numerical simulations based on a Boltzmann kinetic model with competing interactions, aimed at characterizing the rheological properties of soft-glassy materials. The lattice kinetic model is shown to reproduce typical signatures of driven soft-glassy flows in confined geometries, such as...
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PMID: 21576158
PDF is available here.
Abstract
A two-continuous mesophilic (37 ± 2°C) UASB system with step-feed was investigated as an attractive optimization strategy for enhancing COD and total phenols removal of the system and improving aerobic biodegradability of real coal gasification wastewater. Through the step-feed period, the maximum...
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PMID: 21093254
PDF is available here.
Abstract
The sound generated by a vortex propagating across a two-dimensional duct section with flexible walls (membranes) in an infinitely long rigid duct conveying a flow is investigated numerically using the matched asymptotic expansion technique and the potential theory. The effects of the initial vortex...
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PMID: 21568387
PDF is available here.
Abstract
A sorption process for the removal of phosphate was evaluated under various conditions using a filter bed packed with giant reed (GR) based adsorbent. FTIR spectrum measurement validated the existence of grafted amine groups in the adsorbent and Raman spectrum displayed the characteristic peaks of di...
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PMID: 21094604
PDF is available here.
Abstract
Within the viscosity-extended Biot framework of wave propagation in porous media, the existence of a slow shear wave mode with non-vanishing velocity is predicted. It is a highly diffusive shear mode wherein the two constituent phases essentially undergo out-of-phase shear motions (slow shear wave)....
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PMID: 21568383
PDF is available here.
Abstract
A two-continuous mesophilic (37 ± 2°C) UASB system with step-feed was investigated as an attractive optimization strategy for enhancing COD and total phenols removal of the system and improving aerobic biodegradability of real coal gasification wastewater. Through the step-feed period, the maximum...
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PMID: 21093254
PDF is available here.
Abstract
We extend the adhesion model to investigate the adhesive dynamics of Pf-RBCs as a function of wall shear stress (WSS) and other parameters using a three-dimensional, multiscale RBC model. Several types of adhesive behavior are identified, including firm adhesion, flipping dynamics, and slow slipping...
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PMID: 21539775
PDF is available here.
Abstract
Functional and rheological properties of proteins from frozen turkey breast meat with different ultimate pH at 24 h postmortem (pH(24)) have been studied. Sixteen breast fillets from Hybrid Tom turkeys were initially selected based on lightness (L*) values for each color group (pale, normal, and dark...
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PMID: 21489962
PDF is available here.
Abstract
The objective of this article is to describe the formulation and evaluation of dermal semisolid drugs--carbopol hydrogels containing the solution of Bukofit, zinc chloride and the local anaesthetic lidocaine. The hydrogels were evaluated after 2, 7, 14 and 28 days after their preparation and stored a...
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PMID: 21650010
PDF is available here.
Abstract
The purpose of this study was to prepare a temperature-sensitive gel containing silver nanoparticles and to investigate its anti-bacterial properties in vitro. The aqueous gel was prepared using Pluronic F127 (18-22%) and Pluronic F68 (3-9%) in a cold method to obtain a proper gelati...
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PMID: 21612154
PDF is available here.
Abstract
Poly(vinylpyrrolidone) (PVP) hydrogels were crosslinked by gamma irradiation to add structure and rigidity, and then rheological and mucoadhesive properties were evaluated. The effects of PVP concentration, radiation dose, and additives, such as poly(ethylene glycol) (PEG) and glycerol, on rheologica...
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PMID: 21544722
PDF is available here.
Abstract
We present a new heart valve bioreactor, having as its centrepiece a ventricular assist device (VAD), which exposes the cell-scaffold constructs to a wider array of mechanical forces. The pump of the VAD has two chambers: a blood and a pneumatic chamber, separated by an elastic membrane. Pulsatile a...
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PMID: 20687125
PDF is available here.
Abstract
This paper examines an updated version of a lumped mucosal wave model of the vocal fold oscillation during phonation. Threshold values of the subglottal pressure and the mean (DC) glottal airflow for the oscillation onset are determined. Depending on the nonlinear characteristics of the model, an osc...
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PMID: 21428520
PDF is available here.
Abstract
We report the results of an experimental study of the microstructure of dispersions of Carbopol ETD 2050, a model yield-stress fluid. Using two different light scattering instruments, measurements were made over three decades in scattering wave vector, from 0.02 to 25 μm^{-1}. These measurements re...
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PMID: 21517498
PDF is available here.
Abstract
We observe two types of defect creation mechanisms: the buckling instability under dilation, which was reported earlier, as well as a second mechanism due to layer compression....
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PMID: 21517501
PDF is available here.
Abstract
We have developed a simple method to control catechol-Fe(3+) interpolymer cross-linking via pH. The resonance Raman signature of catechol-Fe(3+) cross-linked polymer gels at high pH was similar to that from native mussel thread cuticle and the gels displayed elastic moduli (G') that approach covalen...
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PMID: 21278337
PDF is available here.
Abstract
We biofabricated a thick dermal-like tissue by sequentially combining two steps: a μTPs production and assembly followed by tissue maturation in a purpose-built bioreactor. The μTPs were produced by first seeding bovine primary fibroblasts on gelatine microparticles and then cultivating them in st...
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PMID: 20704470
PDF is available here.
Abstract
By using Fourier transform infrared (FT-IR) spectroscopy in combination with differential scanning calorimetry (DSC) coupled with pressure perturbation calorimetry (PPC), ultrasound velocimetry, Laurdan fluorescence spectroscopy, fluorescence microscopy and atomic force microscopy (AFM), the temperat...
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PMID: 21262194
PDF is available here.
Abstract
We have proposed that mechanical stimulation by FSS across the surfaces of bone cells results in formation of unique signaling complexes called mechanosomes that are launched from sites of adhesion with the extracellular matrix and with other bone cells [1]. Deformation of adhesion complexes at the...
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PMID: 21283581
PDF is available here.
Abstract
The objective of this work was to develop and evaluate reconstitutable suspensions of ibuprofen-loaded microspheres prepared with an acrylic polymer (Eudragit RS-PM). The microspheres were prepared by the quasi-emulsion solvent diffusion technique. To prepare reconstitutable suspension formulation, t...
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PMID: 21796942
PDF is available here.
Abstract
Our goal was to characterize changes in flow and diameter with vascular endothelial cell growth factor A (VEGF-A) and fibroblast growth factor 2 (FGF2). Observations were made in arteriolar networks of the cheek pouch tissue in anesthetized hamsters (pentobarbital 70 mg/kg, i.p., n = 45). Local and...
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PMID: 20606467
PDF is available here.
Abstract
Self-assembled liposome gel from liposome and cholesterol-end capped polyethylene glycol, was systematically investigated by rheological method, especially in the aspect of its recovery ability upon either mechanical deformation or temperature change. The liposome gel was found to have rheological b...
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PMID: 20855187
PDF is available here.
Abstract
We have developed a new model of the CSF system, which by its biophysical characteristics and dimensions imitates the CSF system in cats. The results obtained on a model were compared to those in animals observed during changes of body position. A new model was constructed from two parts with differ...
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PMID: 21648311
PDF is available here.
Abstract
We used poloxamer gels to develop a controlled release formulation of hGH. The objective of this study was to develop an in situ gel forming drug delivery system for hGH using the minimum possible ratio of poloxamer 407 (P407). Decreasing the concentration of poloxamer could reduce the risk of hyper...
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PMID: 21648286
PDF is available here.
Abstract
Abstract The aim of the present study was to assess injection flow rates of metal syringes, with an emphasis on injection speed and the generation of flow pulsations. A cohort of 64 operators (32 practitioners and 32 students) performed 3 consecutive ex vivo simulated injections (SIs...
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PMID: 21679041
PDF is available here.
Abstract
A promising approach to bone tissue engineering lies in the use of perfusion bioreactors where cells are seeded and cultured on scaffolds under conditions of enhanced nutrient supply and removal of metabolic products. Fluid flow alterations can stimulate cell activity, making the eng...
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PMID: 20872752
PDF is available here.
Abstract
We report here a designer self-assembling peptide nanofiber scaffold developed specifically for nerve tissue engineering. We synthesized a peptide FGL-RADA containing FGL (EVYVVAENQQGKSKA), the motif of neural cell adhesion molecule (NCAM), and then attended to make a FGL nanofiber scaffold (FGL-NS)...
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PMID: 20878982
PDF is available here.
Abstract
We briefly review how hMSCs respond to fluid flow stimuli and focus on the signal molecules involved in this mechanotransduction....
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PMID: 20309603
PDF is available here.
Abstract
The following study analyzes the performance of a continuous flow biodiesel reactor/separator. The reactor achieves high conversion of vegetable oil triglycerides to biodiesel while simultaneously separating co-product glycerol. The influence of the flow direction, relative to the gr...
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PMID: 20576564
PDF is available here.
Abstract
Reduced- and low-fat cheeses are desired based on composition but often fall short on overall quality. One of the major problems with fat reduction in cheese is the development of a firm texture that does not break down during mastication, unlike that observed in full-fat cheeses. The objective of t...
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PMID: 20854990
PDF is available here.
Abstract
We found remarkable consistency in some parameters but not in others, suggesting that the Kelvin-Voigt model commonly applied in elasticity-imaging situations is representative of tissue dispersion but the description it offers is incomplete. Data are consistent with the theory that viscoelastic con...
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PMID: 21213570
PDF is available here.
Abstract
N-[(2-Hydroxy-3-trimethylammonium)propyl] chitosan chloride (HTCC) was chemically modified using glycidyltrimethylammonium chloride (GTMAC). A new composite hydrogel was prepared using the mixture of HTCC and α-β-glycerophosphate (α-β-GP). The gelation of HTCC/GP mainly depended on the concentrat...
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PMID: 20862775
PDF is available here.
Abstract
To determine whether fluid flow-induced shear stress affects the differentiation of bone marrow-derived human mesenchymal stem cells (hMSCs) into osteogenic cells.
hMSCs cultured with or without osteogenic differentiation medium were exposed to fluid flow-induced shear stress and analyzed for alkali...
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PMID: 20868327
PDF is available here.
Abstract
We cover the literature containing rheological characterization of the physical properties of peptide and polypeptide-based hydrogels including hydrogel bulk mechanical properties, gelation mechanisms, and the behavior of hydrogels during and after flow (219 references)....
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PMID: 20422104
PDF is available here.
Abstract
Atheroprone regions of the arterial circulation are characterized by time-varying, reversing, and oscillatory wall shear stress. Several in vivo and in vitro studies have demonstrated that flow reversal (retrograde flow) is atherogenic and proinflammatory. The molecular and structural basis for the...
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PMID: 20554908
PDF is available here.
Abstract
The objective of this work was to quantify the kinetic behavior of Dunaliella primolecta (D. primolecta) subjected to controlled fluid flow under laboratory conditions. In situ velocities of D. primolecta were quantified by micron-resolution particle image velocimetry and particle tracking velocimet...
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PMID: 20506336
PDF is available here.
Abstract
We present a first investigation about the non-linear flow properties and transient orientational-order fluctuations observed in the shear-thinning lecithin-water-cyclohexane wormlike micellar system at a concentration near to the zero-shear isotropic-nematic phase transition. From rheological measu...
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PMID: 20532324
PDF is available here.
Abstract
Three commercially available tissue conditioners -Tissue conditioner II (STII), Tissue conditioner (GTC), and Tissue Care (TTC)- were tested using a rheometer to evaluate their viscoelasticity under compression at a constant distortion (10%). Immediately after fabrication, STII showed the highest ha...
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PMID: 20668361
PDF is available here.
Abstract
We call a mixture hydrogel. The mixture contains two ABA-type triblock copolymers poly(d,l-lactic acid-co-glycolic acid)-b-poly(ethylene glycol)-b-poly(d,l-lactic acid-co-glycolic acid) (PLGA-PEG-PLGA) with different block ratios, and one polymer is soluble in water, but the other is not. The aqueou...
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PMID: 20690723
PDF is available here.
Abstract
We show a triphasic force dependence of E-selectin/ligand dissociation that initially behaves as slip bonds, then transitions to catch bonds, and finally transitions again to slip bonds as the force increases. These transitions govern the velocities of neutrophils, HL-60 cells, and Colo-205 cells ro...
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PMID: 20713000
PDF is available here.
Abstract
We investigate the kinetics of flow-induced beta-hairpin folding. Simulations sampling different flow velocities reveal that under flow, beta-hairpin folding is initiated by hydrophobic collapse, followed by interstrand hydrogen-bond formation and turn formation. Adaptive biasing force simulations a...
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PMID: 20713002
PDF is available here.
Abstract
The Staccato system employs a thermal vaporization technology to generate pure drug aerosols with a particle size optimized for alveolar deposition, leading to rapid absorption of the drug into the systemic circulation. Unlike most traditional aerosol-generation techniques, the particle size of the...
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PMID: 20528148
PDF is available here.
Abstract
In this study, flue gas emissions and combustion efficiencies during combustion and co-combustion of olive cake and coal were investigated in a bubbling fluidized bed. Temperature distributions along the combustion column and flue gas concentrations of O(2), CO, SO(2) and NO(x) were measured during...
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PMID: 20347293
PDF is available here.
Abstract
In present study, the feasibility of developing a novel thermo-sensitive hydrogel suitable for injectable formulations based on chitosan and inorganic phosphate was demonstrated. The physicochemical and rheological changes of chitosan/dibasic sodium phosphate solutions as in function with temperatur...
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PMID: 20434557
PDF is available here.
Abstract
We developed two methods, which calculated weights with a substantially reduced number of ACSl lines. The effects on image quality and flow quantification were compared to fully sampled data, standard GRAPPA, and time-interleaved sampling scheme in combination with generalized autocalibrating partia...
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PMID: 20665791
PDF is available here.
Abstract
Oscillation of the ultrasonically driven file toward the groove is more effective in removing dentin debris from the groove than oscillation perpendicular to the groove, which can be related to the fact that there is a high-velocity jet from the file tip in a single direction following the file osci...
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PMID: 20647099
PDF is available here.
Abstract
Passive ultrasonic irrigation is more effective than the Vibringe System or syringe irrigation in removing debris. The sonic device demonstrated significantly better results than syringe irrigation in the apical root canal third.
Copyright 2010 American Association of Endodontists. Published by Els...
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PMID: 20647107
PDF is available here.
Abstract
The aim of this study was to evaluate rheological properties and release of terbinafine (an antifungal drug) from chitosan hydrogels, and test some additives as possible solvents, preservatives and potential chemical penetration enhancers. The release of terbinafine was better from hydrogel with gly...
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PMID: 20662323
PDF is available here.
Abstract
Biomolecules, including protein A, albumin, and immunoglobulin G, are spotted on top of a nanoporous substrate by using a continuous-flow microspotter (CFM) system, which normally produces spots 3 to 4 orders of magnitude more sensitive than conventional biomolecule printing methods....
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PMID: 20564482
PDF is available here.
Abstract
The thermal and rheological properties of clay-containing poly[(butylene succinate)-co-adipate] (PBSA) nanocomposites are reported. The nanocomposites of PBSA with various weight percentages of organically modified montmorillonite (OMMT) loadings have been prepared by melt-mixing in a batch-mixer. T...
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PMID: 21128399
PDF is available here.