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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Substance Abuse Detection (0):
Recent article
Substance Abuse Detection
Abstract
Brief alcohol interventions for patients in trauma settings have demonstrated significant reductions in drinking behaviors, injury related risk behaviors, and subsequent arrests for driving while intoxicated. However, although a number of surveys have examined the knowledge and attitudes of trauma ce...
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PMID: 21817982
PDF is available here.
PDF is available here.
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Ugeskrift for laeger (173)19 2011
Abstract
Abstract
A case-control study was conducted on 204 drivers fatally injured in road traffic accidents in south-eastern Norway during the period 2003-2008. Cases from single vehicle accidents (N = 68) were assessed separately. As controls, 10540 drivers selected in a roadside survey in the same geographical are...
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PMID: 21376919
PDF is available here.
PDF is available here.
Abstract
We used a questionnaire for demographic information, the SIDUC/CICAD for recent use (i.e., in the last 6 hours) of psychoactive substances before arriving to the emergency room, and the AUDIT, to identify alcohol use problems in the last year. Univariate and multivariate logistic regression models w...
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PMID: 21537770
PDF is available here.
PDF is available here.
Abstract
Abstract
Despite well-documented efficacy, US physicians have been relatively slow to embrace the use of buprenorphine for the treatment of opioid dependence. In order to introduce and support the use of buprenorphine across the San Francisco Department of Public Health system of care, the Bu...
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PMID: 21858959
PDF is available here.
PDF is available here.
Abstract
Erythropoietin (Epo) is produced primarily in the kidneys upon low blood oxygen availability and stimulates erythropoiesis in the bone marrow. Recombinant human Epo (rHuEpo), a drug developed to increase arterial oxygen content in patients, is also illicitly used by athletes to impro...
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PMID: 20966191
PDF is available here.
PDF is available here.
Abstract
Results from toxicological analyses in death investigations are used to determine whether foreign substances were a cause of death, whether they contributed to death, or whether they caused impairment. Drug concentrations are likely to change during pre-terminal stages due to altered pharmacokinetic...
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PMID: 20204545
PDF is available here.
PDF is available here.
Abstract
Biomedical Chromatography (24)12 2010
Abstract
Many psychotropic substances are illegally available on the streets and/or via the Internet. This wide distribution has become a serious social problem. To control this problem, many substances have been controlled as 'designated substances' (Shitei-Yakubutsu) in Japan since April 2007 by the Pharma...
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PMID: 21077248
PDF is available here.
PDF is available here.
Abstract
We selected 10,002 drivers involved in a traffic accident or violation between 2007 and 2008 in Shanghai, Suzhou and Wuxi. We checked for the presence of psychoactive drugs from blood samples using liquid chromatography tandem mass spectrometry (LC-MS-MS). Of the 10,002 drivers, 10.5% tested positiv...
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PMID: 20728679
PDF is available here.
PDF is available here.
Abstract
The ADVANCED QUALITY One Step Multi-Drug Screen test is a new urine on-site immunoassay test that is designed to detect multiple drugs of abuse in one time (barbiturates, benzodiazepines, cocaine, methylenedioxymethamphetamine (MDMA), methamphetamine, and opiates group). Thus, the present research w...
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PMID: 21114210
PDF is available here.
PDF is available here.
Abstract
Performance-enhancing substances are illicitly used in elite or amateur sports and may be obtained from the black market due to a cheaper and easier availability. Although various studies have shown that black market products frequently do not contain the declared substances, enormous amounts of ill...
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PMID: 20675162
PDF is available here.
PDF is available here.
Abstract
The objective of this study was to analyze the influence of the variables that predict cocaine abstinence on an outpatient program for the treatment of addiction to this substance. Participants were 80 patients (85% men and 15% women) selected at random from those receiving treatment at a Spanish he...
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PMID: 21053757
PDF is available here.
PDF is available here.
Minnesota medicine (93)8 2010
Abstract
Since government and private industry have instituted urine drug testing to ensure a drug-free work force, an industry dedicated to subverting the results of those tests has developed. This article describes that industry, the types of products it markets, and efforts to curb the sale of those produ...
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PMID: 20862879
PDF is available here.
PDF is available here.
Abstract
Voucher-based reinforcement therapy (VBRT) is an efficacious contingency management intervention for substance use disorders that provides escalating voucher values to reinforce continuous abstinence and typically resets escalated values to the initial low level upon detection of drug use. The object...
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PMID: 20598837
PDF is available here.
PDF is available here.
Abstract
To investigate the prevalence and characteristics of abusive drug exposure among non-fatal motor vehicle driver casualties presenting to a designated trauma centre in Hong Kong.
Cross-sectional study.
Designated trauma centre/regional accident and emergency department in Hong Kong.
Non-fatal motor v...
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PMID: 20683065
PDF is available here.
PDF is available here.
Abstract
We concluded that he had died of pulmonary edema due to combined drug intoxication including proprietary antitussives and cold remedies. Furthermore, there was a strong possibility that he had habitually taken overdoses of those drugs. Herein, the risk of misuse of prescribed and proprietary drugs,...
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PMID: 20106941
PDF is available here.
PDF is available here.
Abstract
The present review describes the diagnostic value of the metabolites of epinephrine, norepinephrine, dopamine, and serotonin in the laboratory diagnosis of drug abuse. The metabolism and effects of these substances in health and drug addiction are considered. A procedure for their analysis is presen...
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PMID: 20886714
PDF is available here.
PDF is available here.
Abstract
These results indicate patients and health professionals share similar risk related to the UPPL regardless of state....
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PMID: 20711944
PDF is available here.
PDF is available here.
The Lancet (376)9735 2010
Abstract
Abstract
Female street sex workers in the UK are often addicted to heroin, and sex work may be a result of the economic drive to fund this addiction. This study looks at outcomes of a primary care drugs treatment intervention for street sex workers who use heroin, using prescribed maintenance treatment with...
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PMID: 20594441
PDF is available here.
PDF is available here.
Abstract
Low urine creatinine is a poor screening test for detecting alcohol consumption among patients on methadone. However, a normal creatinine level has a 96.7% probability of no alcohol urine present in the urine....
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PMID: 20536285
PDF is available here.
PDF is available here.
Wiener klinische Wochenschrift (122)11-12 2010
Abstract
Doping is a phenomenon which in the past years through the various incidences in professional cycling has come more and more into the focus of the public interest. Whilst in the young past the problems were to define the term "doping" exactly, today's problem is to prevent adolescents and children o...
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PMID: 20552290
PDF is available here.
PDF is available here.
Abstract
We aimed to identify cannabigerol (CBG), which in its acid form is one of the main intermediate compounds of the biosynthesis of cannabinoids in hemp, in authority urine samples of proved Cannabis consumers. For this reason we applied the modified method of Kemp et al. to test for CBG, since enzymat...
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PMID: 20614687
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
Alcohol abuse is a major cause of morbidity and mortality and subsequently presents a substantial burden on the NHS. Whether presentations are directly or indirectly linked, the emergency department (ED) holds a predominant role in dealing with this matter. Alcohol withdrawal syndrome is a common co...
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PMID: 20382370
PDF is available here.
PDF is available here.
Abstract
We exposed healthy test subjects (n = 41), as well as persons who were under the influence of drugs and/or medication (n = 105), to different light stimuli and tested the pupillary light reflex using infrared technology. The synoptic examination of numerous parameters, and the possibility of examina...
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PMID: 20593599
PDF is available here.
PDF is available here.
Abstract
Like adult drug courts, juvenile drug courts have proliferated at a rapid rate during the past 15 years, but comparatively little research has been conducted on them. Although a few studies indicate that these programs appear to show promise as an intervention, almost nothing has been published usin...
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PMID: 19106251
PDF is available here.
PDF is available here.
Atención Primaria (42)4 2010
Abstract
Pediatric Emergency Care (26)4 2010
Abstract
Droperidol is a safe and effective medication in the adolescent and young adult population....
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PMID: 20401969
PDF is available here.
PDF is available here.
Abstract
Abstract
Urine drug screening can enhance workplace safety, monitor medication compliance, and detect drug abuse. Ordering and interpreting these tests requires an understanding of testing modalities, detection times for specific drugs, and common explanations for false-positive and false-negative results. E...
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PMID: 20187600
PDF is available here.
PDF is available here.
Abstract
This study attempts to analyse potential gender differences among a group of heroin addicts seeking treatment at a university-based medical centre. The central modality of treatment at this centre is the use of methadone maintenance. Among those patients entering this program there seems to be an em...
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PMID: 20464810
PDF is available here.
PDF is available here.
Abstract
We assessed the biological potentials of these compounds by measuring in vitro their (i) blood cell/whole blood partition coefficient, (ii) binding to plasmatic proteins (Fbp), and (iii) membrane adsorption. Chemical structure was determined with antibody fluorescence polarisation immunoassay (FPIA)...
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PMID: 20338868
PDF is available here.
PDF is available here.
Abstract
Although the levels of testosterone, LH, and FSH did not differ between the 2 groups, the serum concentrations of inhibin B in individuals with a history of testosterone doping were exclusively at or below the lower limit of the normal range for adult men (100-400 pg/mL). Inhibin B was significantly...
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PMID: 20215894
PDF is available here.
PDF is available here.
Drug and Alcohol Review (29)2 2010
Abstract
A half or more of offenders are intoxicated by a psychoactive substance at the time of the homicide, with alcohol the most commonly reported substance. Levels of substances among victims are comparable with those seen among perpetrators. Among both offenders and victims, levels of substances far exc...
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PMID: 20447230
PDF is available here.
PDF is available here.
Abstract
The detection of misuse with naturally occurring steroids is a great challenge for doping control laboratories. Intake of natural anabolic steroids alters the steroid profile. Thus, screening for exogenous use of these steroids can be established by monitoring a range of endogenous steroids, which c...
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PMID: 19962394
PDF is available here.
PDF is available here.
YAKUGAKU ZASSHI (130)2 2010
Abstract
Illegal cannabis (Cannabis sativa L.) cultivation is still a social problem worldwide. Fifty inquiries on cannabis that Research Center for Medicinal Plant Resources (Tsukuba Division) received between January 1, 2000 and March 31, 2009 were itemized in to 8 categories; 1: seed identification, 2: pl...
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PMID: 20118648
PDF is available here.
PDF is available here.
YAKUGAKU ZASSHI (130)2 2010
Abstract
Thirty-two psychotropic substances were listed as designated substances (Shitei-Yakubutsu, 31 compounds and 1 plant) in Japan by the Pharmaceutical Affairs Law in April 2007 for preventing the abuse of these substances. Subsequently, other psychoactive compounds were also added to this category, 40...
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PMID: 20118651
PDF is available here.
PDF is available here.
Abstract
Dependence on illicit drugs during pregnancy is a major public health concern as there may be associated adverse maternal, fetal, and neonatal consequences. Sweat patches (n = 389) were collected from 39 pregnant volunteers who provided written informed consent for this Institutional Review Board-ap...
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PMID: 19927046
PDF is available here.
PDF is available here.
Abstract
Seeds of the opium poppy plant are legally sold and widely consumed as food. Due to contamination during harvesting, the seeds can contain morphine and other opiate alkaloids. The objective of this study is to review the toxicology of poppy seed foods regarding influence on opiate drug tests. Comput...
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PMID: 19901868
PDF is available here.
PDF is available here.
Abstract
This paper explores the question of whether school drug testing is an effective solution to tackle adolescent substance abuse problems. Research studies in major academic databases and Internet websites are reviewed. Several observations are highlighted from the review: (1) there are few research st...
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PMID: 20209380
PDF is available here.
PDF is available here.
Abstract
The difference in positivity rate between the immunoassay and the LC-MS/MS result showed that the nominal 200 ng/mL cutoff of the immunoassay did not apply to 7-aminoclonazepam. This low immunoassay positivity rate is inconsistent with the manufacturer's published cross reactivity data for clonazepa...
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PMID: 20119465
PDF is available here.
PDF is available here.
Abstract
Abstract
Results of diagnostic accuracy and correlation of clinical factors in relation to threshold levels, prevalence of abuse, false-positives, false-negatives, influence of other drugs, and demographic characteristics will be calculated. LIMITATIONS: The limitations include lack of availability of POC te...
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PMID: 20119473
PDF is available here.
PDF is available here.
Psychiatria polska (44)1 2010
Abstract
Approximately 15% of the Polish population abuse alcohol. Early detection of alcohol problems may prevent their further development and progression. The study reviews traditional biomarkers associated with alcohol abuse. The nature of biomarkers, their practical application and limitations in alcoho...
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PMID: 20449986
PDF is available here.
PDF is available here.
Psychiatria polska (44)1 2010
Abstract
An increasing number of new biomarkers of alcohol abuse appear in the literature. The most commonly used biomarkers (5-hydroxytryptophol, fatty acid ethyl esters, ethyl glucuronide, phosphatidyl ethanol, ethyl sulphate, mitochondrial aspartate aminotransferase, carbohydrate deficient transferrin, ac...
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PMID: 20449987
PDF is available here.
PDF is available here.
New Zealand Medical Journal (123)1320 2010
Abstract
Lakartidningen (107)46 2010
Abstract
Lakartidningen (107)46 2010
Abstract
Abstract
We developed a gas chromatography-mass spectrometry (GC-MS) to detect and to give an approximation of the overdose of molecules frequently encountered in drug intoxications. Therefore two hundred eighty seventeen blood samples were collected over a period of one year and allowed us to evaluate and c...
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PMID: 20348049
PDF is available here.
PDF is available here.
Archiv fur Kriminologie (225)3-4 2010
Abstract
When defendants are confronted with evidence of cannabinoids in their blood suggesting consumption of cannabis they sometimes argue that this could only be due to a passive exposure. The small number of controlled studies available showed that tetrahydrocannabinol (THC), the active ingredient of can...
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PMID: 20506708
PDF is available here.
PDF is available here.
Clinical Drug Investigation (30 Suppl 1) 2010
Abstract
Pharmacological therapy has an important place in the management of opioid dependence. Methadone has been the mainstay of therapy but has a number of limitations. Buprenorphine monotherapy is another option, but misuse and diversion can have negative consequences. The opioid receptor antagonist, nal...
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PMID: 20450241
PDF is available here.
PDF is available here.
Clinical Drug Investigation (30 Suppl 1) 2010
Abstract
Abuse and misuse of pharmacological therapies represent major challenges in the healthcare system, particularly in patients receiving long-acting opioid drugs for the treatment of heroin or opioid addiction. The partial mu-opioid receptor agonist buprenorphine is used to treat opioid dependence, but...
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PMID: 20450243
PDF is available here.
PDF is available here.
Clinical Drug Investigation (30 Suppl 1) 2010
Abstract
We evaluated the effect on misuse/diversion, quality of care, quality of life and service delivery. Seventy-eight patients were switched to buprenorphine/naloxone from either methadone or buprenorphine alone; the median duration of previous buprenorphine or methadone treatment was 10 years. Patients...
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PMID: 20450244
PDF is available here.
PDF is available here.
Clinical Drug Investigation (30 Suppl 1) 2010
Abstract
We describe the results of an observational study investigating the safety and efficacy of buprenorphine/naloxone in opioid-dependent patients. A total of 77 patients were included and were switched from buprenorphine to sublingual tables of buprenorphine/naloxone; the buprenorphine dosage was titra...
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PMID: 20450242
PDF is available here.
PDF is available here.
The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique (17)1 2010
Abstract
As drug abuse in our society escalates, child protection workers face mounting challenges in accurately assessing parental substance abuse in the interest of effective child protection. The impartial evaluation of substance use and abuse is fundamental, requiring objective and sensitive methods. A v...
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PMID: 20436210
PDF is available here.
PDF is available here.