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Articles on Micromanipulation
Improving redundant robotic manipulator precision using heuristic motion resolution measures
Kinematically redundant robotic manipulators are capable of concurrently achieving multiple manipulation goals, including collision avoidance and energy minimisation, by resolving kinematic null spaces. Given specifications for manipulator joint motion resolution and accuracy, null spaces can also be...
Probe type micro magnetic manipulator utilising localised magnetic field with closed–loop magnetic path
This paper describes a novel manipulation technique of a single micrometer–scale magnetic particle using a localised magnetic field. An electromagnetic probe consisting of a glass nanopipette was fabricated by coating with ferromagnetic materials inside and outside the nanopipette. The probe edge c...
[Wavefront engineering for two-photon excitation of optogenetic tools].
Two-dimensional manipulation of micro particles by acoustic radiation pressure in a heptagon cell.
An acoustic particle manipulation system is presented, using a flexible printed circuit board formed into a regular heptagon. It is operated at 4 MHz and has a side dimension of 10 mm. The heptagonal geometry was selected for its asymmetry, which tends to reduce standing wave behavio...
Automated transportation of single cells using robot-tweezer manipulation system.
We propose to use a robot-tweezer manipulation system to solve the problem of automatic transportation of biological cells, where optical tweezers function as special robot end effectors. Dynamics equation of the cell in optical tweezers is analyzed. A closed-loop controller is designed for transpor...
Selection of antibodies against a single rare cell present in a heterogeneous population using phage display.
We describe a new method applying phage-displayed antibody libraries to the selection of antibodies against a single identified cell on a glass slide. This is the only described method that has successfully achieved selection of antibodies against a single rare cell in a heterogeneous population of...
Potential-well model in acoustic tweezers--comment.
The production of acoustical vortices-based potential wells for particle trapping is not only restricted to the use of a Laguerre-Gaussian beam. Other useful types of vortex beams include an r-vortex beam, a non-diffracting high-order Bessel and Bessel-Gauss beam, a fractional (diffr...
Phase contrast optical tweezers.
We report on systematic theoretical and experimental investigation of Phase Contrast Optical Tweezers (PCOT) which could be an indispensable tool for micromanipulation of the transparent micro and nano objects such as biological tissues and vesicles. The quadrant photodiode detection scheme and the...
Dynamic manipulation and patterning of microparticles and cells by using TiOPc-based optoelectronic dielectrophoresis.
We develop light-driven optoelectronic tweezers based on the organic photoconductive material titanium oxide phthalocyanine. These tweezers function based on negative dielectrophoresis (nDEP). The dynamic manipulation of a single microparticle and cell patterning are demonstrated by using this light...
Handheld mechanical cell lysis chip with ultra-sharp silicon nano-blade arrays for rapid intracellular protein extraction.
This paper presents a handheld mechanical cell lysis chip with ultra-sharp nano-blade arrays fabricated by simple and cost effective crystalline wet etching of (110) silicon. The ultra-sharp nano-blade array is simply formed by the undercutting of (110) silicon during the crystalline wet etching pro...