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Glycerides (3):
Recent article
Glycerides
Abstract
The impact of applying edible oils to corn silks on ear-feeding insects in sweet corn, Zea mays L., production was evaluated in 2006 and 2007. Six edible oils used in this experiment were canola, corn, olive, peanut, sesame, and soybean. Water and two commercial insecticidal oils (Neemix neem oil and...
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PMID: 21735916
PDF is available here.
PDF is available here.
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Abstract
We investigated two mechanistically distinct eCB-mediated responses to address this issue. We now report that pharmacological inhibitors of DGLα have quantitatively different effects on eCB-mediated responses triggered by different stimuli, suggesting that functional, and perhaps physical, distinct...
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PMID: 21305054
PDF is available here.
PDF is available here.
Abstract
4.6 nm-sized aminosilane-modified maghemite (γ-Fe(2)O(3)) nanoparticles (aMNPs) were synthesized and encapsulated into onion-type multilamellar vesicles of soybean phosphatidylcholine (90%mol) and monoolein (10%mol). The magnetic multilamellar vesicles were obtained by shearing lipids with an aqueo...
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PMID: 20820553
PDF is available here.
PDF is available here.
Abstract
We measured circulating OEA, AEA and 2-AG in patients with sleep apnea (n = 20) and healthy control subjects (n = 57). Respiratory distress index (RDI) as measured by polysomnography was used as a quantitative index of sleep apnea.
In patients with sleep apnea OEA serum concentrations were significa...
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PMID: 20429051
PDF is available here.
PDF is available here.
Neuroscience (169)3 2010
Abstract
We tested the hypothesis that activation of the glutamatergic input to a neuron leads to an endocannabinoid-mediated suppression of the GABAergic afferent input to the same neuron. Spontaneous postsynaptic currents (sPSCs) were recorded with patch-clamp techniques in Purkinje cells in mouse cerebell...
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PMID: 20553815
PDF is available here.
PDF is available here.
Bioresource Technology (101)15 2010
Abstract
In this study free fatty acids present in Azadirachta indica (Neem) oil were esterified with our synthesized phosphoric acid modified catalyst. During the esterification, the acid value was reduced from 24.4 to 1.8 mg KOH/g oil. Synthesized catalyst was characterized by NH(3) TPD, XRD, SEM, FTIR and...
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PMID: 20346652
PDF is available here.
PDF is available here.
Abstract
We explored the potential role of transient receptor potential (TRP) channels in this process. Previously, we observed that after metabolism AEA and arachidonic acid (ArA) can be recycled into new endocannabinoid molecules. Consistent with these previous findings, we found that Cath.a differentiated...
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PMID: 20466028
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)26 2010
Abstract
We show that the endocannabinoid 2-arachidonoyl-glycerol (2-AG) is synthesized in both olfactory receptor neurons and glia-like sustentacular cells in larval Xenopus laevis. Its production in the latter depends on the hunger state of the animal. The essential effect of 2-AG in olfactory receptor neu...
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PMID: 20592217
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)25 2010
Abstract
We tested whether RA and its receptors may regulate CB(1)R expression in cultured mouse hepatocytes. Incubation of hepatocytes with RA or RA receptor (RAR) agonists increased CB(1)R mRNA and protein, the most efficacious being the RARgamma agonist CD437 and the pan-RAR agonist TTNPB. The endocannabi...
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PMID: 20410309
PDF is available here.
PDF is available here.
Pharmacological Research (61)5 2010
Abstract
We examined the role of the endocannabinoid system in regulating this locomotor response in OBX and sham-operated rats. In our study, OBX-induced hyperactivity was restricted to the first 3 min of the open field test, demonstrating the presence of novelty (0-3 min) and habituation (3-30 min) phases...
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PMID: 20044005
PDF is available here.
PDF is available here.
Neurobiology of Disease (38)2 2010
Abstract
We report that a single dose of the neuroprotective endocannabinoid 2-arachidonoyl glycerol (2-AG) administered early after SCI reduces lesion expansion, which was prevented by simultaneous blockade of both CB1 and CB2 receptors but not by blockade of either receptor alone. Treatment with 2-AG also...
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PMID: 20156559
PDF is available here.
PDF is available here.
Abstract
We showed for hexagonal and emulsified micellar phase particles that the increase of the stabilizer content induced a strong decrease of the mean hydrodynamic size of the particles, allowing producing nanostructured lipid-based liquid crystalline particles down to a radius of 70 nm at the same energ...
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PMID: 20143786
PDF is available here.
PDF is available here.
Abstract
The objectives of this study are to enhance cellular accumulation of gemcitabine with chitosan/glyceryl monooleate (GMO) nanostructures, and to provide significant increase in cell death of human pancreatic cancer cells in vitro. The delivery system was prepared by a multiple emulsion solvent evapor...
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PMID: 20238190
PDF is available here.
PDF is available here.
Abstract
A self-microemulsifying drug delivery system (SMEDDS) has been developed to enhance diffusion rate and oral bioavailability of valsartan. The solubility of valsartan was checked in different oils, surfactants, and cosurfactants and ternary phase diagrams were constructed to evaluate the microemulsio...
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PMID: 20182825
PDF is available here.
PDF is available here.
Dental Materials Journal (29)2 2010
Abstract
We reported that the integrity of a resin composite restoration deteriorated when the dentin cavity wall was decalcified by conditioning. In this study, to evaluate the bonding between dentin adhesive and non-decalcified dentin surface, we experimented with a novel method of using a high-pressure wa...
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PMID: 20379031
PDF is available here.
PDF is available here.
Vnitrni lekarstvi (56)2 2010
Abstract
The endocannabinoid system is an endogenous signaling system that plays a role in the regulation of energy homeostasis and lipid and glucose metabolism-all of which can influence cardiometabolic risk. The endocannabinoid system is normally a silent physiologic system that becomes transiently activat...
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PMID: 20329583
PDF is available here.
PDF is available here.
Abstract
The effects of tri- and monoglycerides on phospholipid (POPC) membranes were studied using spectroscopical methods. Triolein was found to form two types of POPC-rich membranes, both with POPC or as a three-component system with monopalmitin. These two membrane types were determined as co-existing ph...
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PMID: 19962372
PDF is available here.
PDF is available here.
Abstract
To study the prescription and technique of sustained-release dropping pills of curcumin and inspect their release property in vitro.
The orthogonal test was used to screen the prescription and technique which were definited with the colligation evaluation of release and formation of dropping pills....
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PMID: 20518316
PDF is available here.
PDF is available here.
Neotropical Entomology (39)4 2010
Abstract
Aqueous solutions of neem oil and aqueous extracts of neem seeds and leaves were sprayed on coffee fruits for laboratory evaluation of their efficiency in reducing infestation of the coffee borer, Hypothenemus hampei (Ferrari), in multi-choice preference assays in laboratory. Neem oil and extracts r...
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PMID: 20878003
PDF is available here.
PDF is available here.
Neotropical Entomology (39)4 2010
Abstract
We evaluated the efficiency of alternative products to control T. evansi on tomato plants under greenhouse conditions. The products tested were lime sulphur and neem based products. We first estimated the lethal concentration (LC) and instantaneous rate of increase (r i) of T. evansi exposed to diff...
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PMID: 20878004
PDF is available here.
PDF is available here.
Current Medicinal Chemistry (17)14 2010
Abstract
The cannabinoid CB1 and CB2 receptors are Class A G protein-coupled receptors (GPCRs). While many Class A GPCRs have endogenous ligands that are hydrophilic cations (e.g., the serotonin and dopamine receptors), the cannabinoid receptors have neutral, highly lipophilic ligands derived from the fatty...
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PMID: 20166921
PDF is available here.
PDF is available here.
Current Medicinal Chemistry (17)14 2010
Abstract
Endocrine Journal (57)6 2010
Abstract
The present study summarized recent findings on roles of leptin and endocannabinoids as modulators of the peripheral components of sweet taste. The positive effect of endocannabinoids on sweet sensitivity was opposed to that of leptin which suppresses sweet sensitivity. Leptin and endocannabinoids,...
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PMID: 20431269
PDF is available here.
PDF is available here.
Abstract
A series of new modifications of alkyl cationic glycerolipids with hetero polar domain has been synthesized. The most active compound rac-N-(4-[(2-ethoxy-3-octadecyloxy)prop-1-yloxycarbonyl]butyl)-N'-etylimidazoliyiodid in micromolar concentrations causes a delay of cell cycle in phase G1, DNA fragm...
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PMID: 20823928
PDF is available here.
PDF is available here.
Abstract
We studied adipocyte phenotypes, viability, and differentiation (CCAAT/enhancer-binding protein alpha [C/EBPalpha] and peroxisome proliferator-activated receptor gamma [PPARgamma] expression) and adiponectin production, mtDNA content, mitochondrial membrane potential, mitochondrial mass, and respira...
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PMID: 19805555
PDF is available here.
PDF is available here.
Abstract
The control of Lepidoptera pests should be carried out before hatching of their caterpillars to avoid damage to the crops. The aim of this work was to assess the activity of neem (trade name: Natuneem, producer: Base Fértil, Chapadão do Sul, Brazil) and pyroligneous extracts (trade name: Biopirol...
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PMID: 20653245
PDF is available here.
PDF is available here.
Abstract
The therapeutic potential of cannabinoids has been the topic of extensive investigation following the discovery of cannabinoid receptors and their endogenous ligands. Cannabinoid receptors and their endogenous ligands are present at supraspinal, spinal and peripheral levels. Cannabinoids suppress be...
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PMID: 19839937
PDF is available here.
PDF is available here.
Abstract
Thin layer chromatography (TLC) stained with hot acidic p-anisaldehyde, is an interesting, fast, and low-cost technique to monitor main lipid contaminants such as triacylglycerols, diacylglycerols, and monoacylglycerols in biodiesel. These acylglycerols are detectable by the proposed planar chromato...
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PMID: 19835701
PDF is available here.
PDF is available here.
Abstract
We investigated the enzymatic degradation of 2-acylglycerols in rabbit platelets and we characterized the responsible enzyme(s). [(3)H]2-AG and [(3)H]2-oleoylglycerol (2-OG) were both metabolized to [(3)H]glycerol and the respective fatty acid in a time and protein concentration-dependent manner, ap...
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PMID: 19811221
PDF is available here.
PDF is available here.
Chemistry & Biology (16)7 2009
Abstract
We recently reported a piperidine carbamate, JZL184, that inhibits MAGL with high potency and selectivity. Here, we describe a comprehensive mechanistic characterization of JZL184. We provide evidence that JZL184 irreversibly inhibits MAGL via carbamoylation of the enzyme's serine nucleophile. Funct...
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PMID: 19635411
PDF is available here.
PDF is available here.
Nutritional Neuroscience (12)4 2009
Abstract
Conjugated linoleic acid (CLA) has a role of biogenic regulation through modifying prostaglandin production. However, its effects on related metabolites of arachidonate remain unclear. Therefore, the effects of CLA on brain endocannabinoid content as well as its analogs were investigated. Mice (3-we...
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PMID: 19622239
PDF is available here.
PDF is available here.
Journal of wound care (18)7 2009
Abstract
Aloe vera was the most adsorbent of the biopolymers and a 40% dilution had comparable values to those of the ACC dressings. Furthermore, values for the novel composite dressing were similar to those of the ACC dressings. CONCLUSION: The novel composite dressing may be a potential alternative to ACC...
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PMID: 19827482
PDF is available here.
PDF is available here.
Medical Science Monitor (15)6 2009
Abstract
It was demonstrated that the microtubule and microfilament network is involved in the incorporation of FAs and in its channeling to neutral lipids and phospholipids. These effects had differential characteristics depending on the type of FA involved and may have potential significance in the underst...
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PMID: 19478693
PDF is available here.
PDF is available here.
Abstract
These results are in good agreement with previous studies on the interaction of GMO-based CPNPs with planar bilayers using neutron reflectivity, where the diffraction peak shifted with time upon mixing. The structural changes are much less prominent for the PtOH-based CPNPs and the HPNPs upon mixing...
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PMID: 19714888
PDF is available here.
PDF is available here.
Abstract
Liquid-crystalline cubic-phase nanoparticles (CPNPs) (known as Cubosome particles), based on the lipid glycerol monooleate and stabilized by the nonionic block copolymer Pluronic F-127, interact with supported model membranes consisting of dioleoylphosphatidylcholine (DOPC) in a complex and dynamic...
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PMID: 19714826
PDF is available here.
PDF is available here.
Journal of Neurochemistry (109)2 2009
Abstract
We addressed the possible role of lipid rafts in the control of endocannabinoid system in striatal slices. Disruption of lipid rafts following cholesterol depletion with methyl-beta-cyclodestrin (MCD) failed to affect synthesis and degradation of anandamide, while it caused a marked increase in the...
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PMID: 19187444
PDF is available here.
PDF is available here.
Abstract
Liacarus subterraneus is a large, soil-dwelling oribatid mite species that possesses a conspicuously shiny, clean and not wettable cuticular surface. The exocrine cuticular chemistry of this species was investigated by means of gas chromatography-mass spectrometry. Besides a fraction of hydrocarbons...
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PMID: 19005767
PDF is available here.
PDF is available here.
Abstract
We used the rat hippocampal slice preparation to study and compare the effect of various synthetic and endogenous CB1 ligands on excitatory synaptic transmission. The full CB1 agonist WIN55212-2 (WIN2) greatly decreased excitatory synaptic transmission by 62%. The effect of WIN-2 was concentration d...
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PMID: 18816788
PDF is available here.
PDF is available here.
Abstract
We found that carbamazepine and cholesterol (type I molecules) likely localize in the hydrophobic domains, but close to the hydrophobic-hydrophilic region. They induce strong perturbation to the mesophase packing by influencing both the order of the lipid acyl chains and interactions between lipid h...
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PMID: 18781793
PDF is available here.
PDF is available here.
Abstract
These results document the potential for botanical formulations to control white grubs, but blending extracts from diverse botanical sources does not ensure enhanced biological activity....
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PMID: 19253649
PDF is available here.
PDF is available here.
Enzymatic Re-esterification of Lower Glycerides from Soybean Oil with Conjugated Linoleic Acid (CLA)
Abstract
New structured lipids essentially free of saturated fatty acids and rich in essential fatty acids and CLA were prepared from soybean oil using a selective enzymatic procedure of synthesis. Saturated fatty acids originally present in the oil were selectively removed in a selective alcoholysis step. E...
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PMID: 19113872
PDF is available here.
PDF is available here.
Abstract
The stability against coalescence of vegetable oil-in-water "food grade" emulsions in the presence of both surfactant (monoolein) and colloidal particles (hydrophilic silica) has been studied and compared to the stability of systems where only the low molecular weight surfactant or the colloidal par...
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PMID: 18977494
PDF is available here.
PDF is available here.
AAPS PharmSciTech (10)4 2009
Abstract
Different lipids were melted and resolidified as model systems to gain deeper insight into the principles of recrystallization processes in lipid-based dosage forms. Solid-state characterization was performed on the samples with differential scanning calorimetry and X-ray powder diff...
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PMID: 19862628
PDF is available here.
PDF is available here.
AAPS PharmSciTech (10)4 2009
Abstract
Different lipids were melted and resolidified as model systems to gain deeper insight into the principles of recrystallization processes in lipid-based dosage forms. Solid-state characterization was performed on the samples with differential scanning calorimetry and X-ray powder diff...
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PMID: 19862628
PDF is available here.
PDF is available here.
AAPS PharmSciTech (10)4 2009
Abstract
Different lipids were melted and resolidified as model systems to gain deeper insight into the principles of recrystallization processes in lipid-based dosage forms. Solid-state characterization was performed on the samples with differential scanning calorimetry and X-ray powder diff...
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PMID: 19862628
PDF is available here.
PDF is available here.
Abstract
We applied hamster biliary cancer model, a difficult cancer to treat. Cancer (KIGB-5) cells were given intravenously to produce hematogenous metastatic lung lesions which were treated with EC-18 at 10, 25, and 50 mg/kg/day respectively. The fourth group was untreated control. At 4th, 8th, and 12th w...
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PMID: 19543512
PDF is available here.
PDF is available here.
Abstract
Most of the sustained release vaginal formulations are in the form of bioadhesive gels and tablets. Though proved efficient, their presence in the vagina for a longer time as a bulk produces discomfort and interference with body functioning including sexual activities. Hence, they lack complete pati...
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PMID: 18802845
PDF is available here.
PDF is available here.
Neotropical Entomology (38)4 2009
Abstract
This work aimed to determine the efficiency of the entomopathogenic fungi Metarhizium anisopliae and Beauveria bassiana to control the aphid Lipaphis erysimi (Kalt.) (Hemiptera: Aphididae) in kale Brassica oleracea var acephala D.C., as well as their compatibility with a neem oil formulation (Neemse...
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PMID: 19768273
PDF is available here.
PDF is available here.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques (12)1 2009
Abstract
Good emulsification with nano sized droplets was observed for SES 30% as compared to micron sized droplets for other SES. In polarizing microscopy, formation of intermediate LC phase was observed in all SES. Lamellar phase was evident in 30% SES while other SES exhibited micellar cubic phase. Presen...
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PMID: 19470290
PDF is available here.
PDF is available here.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques (12)2 2009
Abstract
SES Plain exhibited 'bad' emulsification owing to instantaneous gel formation in aqueous media. Almost all SES C have shown 'good' emulsification with transparent appearance, very low turbidity value and nano size droplets. All SES P presented 'moderate' emulsification with milky appearance, high tu...
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PMID: 19732494
PDF is available here.
PDF is available here.
Abstract
In comparison with healthy controls, there were no significant differences in measured eCB concentrations in plasma samples from patients with AD. Detectable eCBs in cerebrospinal fluid (CSF) had no relationship to cognitive performance in healthy controls at risk for AD. In pooled plasma samples, a...
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PMID: 19144193
PDF is available here.
PDF is available here.
Journal of Oleo Science (58)3 2009
Abstract
Thirty-five glycerol-assimilating bacteria have recently been isolated from soil samples. Amplified ribosomal DNA restriction analysis revealed that these strains are grouped into four genetically different types of bacteria. Gas chromatography-mass spectrometry analysis of glycerol metabolites prod...
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PMID: 19202313
PDF is available here.
PDF is available here.
Abstract
These results indicate that the studied MN-SLN formulation with skin targeting may be a promising carrier for topical delivery of miconazole nitrate....
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PMID: 19294517
PDF is available here.
PDF is available here.
Abstract
We report a potent and selective inhibitor of MAGL called JZL184 that, upon administration to mice, raises brain 2-AG by eight-fold without altering anandamide. JZL184-treated mice exhibited a broad array of CB1-dependent behavioral effects, including analgesia, hypothermia and hypomotility. These d...
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PMID: 19029917
PDF is available here.
PDF is available here.
Abstract
We investigated whether human erythroleukemia (HEL) cells were able to bind, metabolise and transport the main endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG). We also investigated whether AEA or 2-AG could modulate HEL differentiation. Although able to internalise both endocann...
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PMID: 18820887
PDF is available here.
PDF is available here.
Abstract
In the present study the initial blood compatibility of glycerol monooleate (GMO)-coated surfaces was evaluated after deposition to surfaces and in bulk. The model surface was silica onto which multiple layers of fibrinogen or human serum albumin (HSA) was immobilized. The protein-coated surfaces we...
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PMID: 18996684
PDF is available here.
PDF is available here.
BioFactors (35)1 2009
Abstract
2-Arachidonoylglycerol is an arachidonic acid-containing monoacylglycerol isolated from the rat brain and canine gut as an endogenous ligand for the cannabinoid receptors (CB1 and CB2). 2-Arachidonoylglycerol binds to both the CB1 receptor, abundantly expressed in the nervous system, and the CB2 rec...
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PMID: 19319851
PDF is available here.
PDF is available here.
Abstract
The objective of this investigation was to assess the quantity of collagen fibers with different dosages of recombinant human bone morphogenetic protein, type 2 (rhBMP-2) associated with two different carriers, monoolein and poloxamer gels, in critical bone defects created in the cal...
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PMID: 19394235
PDF is available here.
PDF is available here.
Abstract
The objective of this investigation was to assess the quantity of collagen fibers with different dosages of recombinant human bone morphogenetic protein, type 2 (rhBMP-2) associated with two different carriers, monoolein and poloxamer gels, in critical bone defects created in the cal...
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PMID: 19394235
PDF is available here.
PDF is available here.
Abstract
The objective of this investigation was to assess the quantity of collagen fibers with different dosages of recombinant human bone morphogenetic protein, type 2 (rhBMP-2) associated with two different carriers, monoolein and poloxamer gels, in critical bone defects created in the cal...
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PMID: 19394235
PDF is available here.
PDF is available here.