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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Polymers (15):
Recent article
Polymers
Abstract
This article reviews current applications and novel candidate biomaterials for use as tissue-engineered scaffolds in pediatric cardiac tissue engineering. This overview of different types of biomaterials includes naturally derived and synthetic polymers and their biological, physical...
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PMID: 21647794
PDF is available here.
PDF is available here.
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Abstract
Abstract
Tissue engineering promises to restore tissue and organ function following injury or failure by creating functional and transplantable artificial tissues. The development of artificial tissues with dimensions that exceed the diffusion limit (1-2 mm) will require nutrients and oxygen...
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PMID: 21892744
PDF is available here.
PDF is available here.
Abstract
The present investigation concerns with the development and optimization of a bipolymeric delivery device for the treatment of colonic diseases. Prednisolone - a popular glucorticoid was used a model drug. The formulations were designed with an objective to deliver the drug to the large bowel with a...
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PMID: 21928719
PDF is available here.
PDF is available here.
Abstract
The authors have investigated the adsorption-elution of intestinal bacteriophages T2 and MS2 as a model of enteric viruses, by using the coagulants aluminum oxychloride (AOX78) and aluminum sulfate (AS). The investigation has ascertained the effective removal of the phages from water with AOX78 (98.7...
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PMID: 21842744
PDF is available here.
PDF is available here.
Abstract
Recently, poly(ester urethanes) were investigated for use as ligament grafts due to their exceptional mechanical properties and highly tunable structure; however, these grafts are susceptible to hydrolytic degradation that occurs independent of tissue regeneration. To address this li...
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PMID: 21681959
PDF is available here.
PDF is available here.
Ultrasonic Imaging (33)3 2011
Abstract
We described a 5 MHz center frequency PZT-P[VDF-TrFE] dual-layer transducer that used two perpendicular 1-D arrays for 3-D rectilinear imaging. This design substantially reduces the channel count as well as fabrication complexity, which makes 3-D imaging more realizable. Higher frequencies (>5 MHz)...
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PMID: 21842584
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)7 2011
Abstract
Ultrathin films (also called nanofilms) are two-dimensional (2-D) polymeric structures with potential application in biology, biotechnology, cosmetics and tissue engineering. Since they can be handled in liquid form with micropipettes or tweezers they have been proposed as flexible s...
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PMID: 21421086
PDF is available here.
PDF is available here.
Abstract
Poly(N,N-diethylacrylamide) (PDEAAm) hydrogel scaffolds were prepared by radical copolymerization of N,N-diethylacrylamide (DEAAm), N,N'-methylenebisacrylamide and methacrylic acid in the presence of (NH₄)₂SO₄ or NaCl. The hydrogels were characterized by low-vacuum scanning ele...
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PMID: 21563303
PDF is available here.
PDF is available here.
Abstract
These results indicate that the gelatin/PLLA nanocylinder composite is a promising way to fabricate 3D nanofibrous scaffolds that accelerates cell adhesion and proliferation for tissue engineering....
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PMID: 22121718
PDF is available here.
PDF is available here.
Abstract
We synthesize a new cationic water-soluble CP containing fluorene moiety and flexible ethylenic moiety in the backbone (PFV) for label-free DNA detection. The conformational freedom of PFV provides stronger interactions with double-stranded DNA (dsDNA) and optimizes the orientation of transition mom...
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PMID: 21093227
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
Currently, biomedical engineering is rapidly expanding, especially in the areas of drug delivery, gene transfer, tissue engineering, and regenerative medicine. A prerequisite for further development is the design and synthesis of novel multifunctional biomaterials that are biocompati...
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PMID: 21469742
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
We demonstrate that PEMs constructed from CS as the polyanion display a low Young's modulus correlated with poorly supported cell adhesion and proliferation. When the CS was adsorbed onto a stiffer polypeptide PEM basis, the Young's modulus increased, and the cell response was significantly improved...
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PMID: 21491904
PDF is available here.
PDF is available here.
Abstract
The additive manufacturing technique selective laser melting (SLM) has been successfully proved to be suitable for applications in implant manufacturing. SLM is well known for metal parts and offers direct manufacturing of three-dimensional (3D) parts with high bulk density on the ba...
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PMID: 21495168
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
This Review is focused on the growing interest brought to phosphorus-containing organic materials for applications in the biomedical field, mainly because of their properties such as biocompatibility, hemocompatibility, and protein adsorption resistance. It mainly describes relevant...
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PMID: 21553908
PDF is available here.
PDF is available here.
Abstract
The SEBMAS degraded gradually after being implanted into the rabbit aorta, and total biocorrosion occurred after ∼120 days. In all groups, the lumen area was significantly greater, but the neointimal area was significantly smaller in SEBMAS segments compared with the uncoated BMAS segments (p<0.0...
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PMID: 21679083
PDF is available here.
PDF is available here.
Biomedical Materials (6)3 2011
Abstract
A key step during the synthesis of collagen constructs is the incubation of monomeric collagen in phosphate buffer saline (PBS) to promote fibrillogenesis in the collagen network. Optimal PBS-treatment conditions for monomeric collagen solutions to induce gelation are well establishe...
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PMID: 21540522
PDF is available here.
PDF is available here.
Abstract
We would like to pursue with our sutureless tissue fusion research. The primary concern in sutureless tissue fusion- and especially in tissue fusion of cerebral vessels- is the lack of reproducibility, often caused by variations in the thermal damage of the vessel. This has prevented this novel fusi...
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PMID: 21691987
PDF is available here.
PDF is available here.
Abstract
Abstract
I (placeStateCol I) and osteocalcin (OC) deposition exhibited fiber orientation dependence. With an increase in parallelism of the fibers, there was a decrease in ALP activity and placeStateCol I and OC production. These results suggest that exploitation of PLLA fiber orientation may be used to cont...
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PMID: 21396609
PDF is available here.
PDF is available here.
Abstract
Photo-reaction by UV irradiation of a highly fluorescent s-triazine bridged p-phenylenevinylene polymer resulted in micro and submicron fluorescent pattern because carbonyl group (C=O) was generated from vinylene group (C=C) through the photo-oxidation. This fluorescent pattern could...
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PMID: 21780472
PDF is available here.
PDF is available here.
Abstract
Heart failure remains the leading cause of death in many industrialized nations owing to the inability of the myocardial tissue to regenerate. The main objective of this work was to develop a cardiac patch that is biocompatible and matches the mechanical properties of the heart muscl...
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PMID: 21247338
PDF is available here.
PDF is available here.
Abstract
I imprinted sol-gel was prepared by mixing Sudan I with 3-aminopropyltriethoxysilane, tetraethoxysilane, chitosan, and AuNPs, followed by copolymerization and extraction of the template molecules. The hybrid forming membrane was characterized by SEM and FTIR-ATR, and used for the linear sweep voltam...
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PMID: 21376972
PDF is available here.
PDF is available here.
Abstract
Abstract
We developed microfibrous scaffolds made from blends of PGS and poly(ε-caprolactone) (PCL) using a standard electrospinning set-up. At a given PGS:PCL ratio, higher voltage resulted in significantly smaller fibre diameters (reduced from ∼4 µm to 2.8 µm; p < 0.05). Further increase in voltage re...
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PMID: 20669260
PDF is available here.
PDF is available here.
Abstract
Our previous study has shown significant improvement in tensile properties of these materials due to the enhanced interfacial adhesion between the polymer matrix and HA particles. To further investigate the potential applications of these composites in bone repair and other orthopedic surgeries, a s...
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PMID: 21416229
PDF is available here.
PDF is available here.
Abstract
We therefore examined an absorbable polyglycolic acid (PGA) biomaterial for its utility to support disc tissue regeneration. Microdiscectomy for lumbar disc herniation was performed in six patients. Intervertebral disc cells were isolated and in vitro cell expansion was accomplished using human seru...
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PMID: 20661901
PDF is available here.
PDF is available here.
Abstract
Our plastination model exhibited a high level of anatomic quality, including a very good mucosa preservation. Aerodynamical and geometrical investigations highlighted a global behaviour of plastinated models perfectly in accordance with a nasal decongested healthy subject.
The presen...
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PMID: 21468371
PDF is available here.
PDF is available here.
Abstract
We tested the effect of pore sizes on construct properties by histological, biochemical, and mechanical evaluations. Histological analysis revealed circumferentially organized extracellular matrix proteins including elastin and the presence of multilayered SMCs expressing calponin and α-smooth musc...
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PMID: 21282618
PDF is available here.
PDF is available here.
Abstract
Drug eluting stent (DES) dramatically reduced the instent restenosis(ISR). However, very late stent thrombosis appeared as another significant problem especially after the termination of dual antiplatelet therapy. The next-generation DESs are characterized by either biodegradable polymer, controlled...
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PMID: 21387669
PDF is available here.
PDF is available here.
Abstract
Abstract
We report the synthesis and characterization of a novel cross-linked N-isopropylacrylamide-acrylic acid-hydroxyethyl methacrylate [P (NIPASM-AA-HEM)] hydrogel nanoparticles (NPs) containing amoxicillin. The aim of present study was to investigate whether these hydrogel NPs have the potential to be u...
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PMID: 21280053
PDF is available here.
PDF is available here.
Abstract
Over the past two decades the dopamine D2 receptor has been undoubtedly the most widely studied dopamine receptor for the therapeutic treatment of schizophrenia, as the majority of antipsychotics exhibit antagonism at this receptor. However, the cognitive symptoms of the disorder are...
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PMID: 21199449
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)2 2011
Abstract
We demonstrated that the thermosensitive matrices promoted cell detachment, thus P(D,L)LA scaffolds have the potential to be used as substrates for cell growth and expansion avoiding enzymatic and mechanical methods of cell harvesting. The harvested cells were replated to evaluate their viability, w...
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PMID: 20883833
PDF is available here.
PDF is available here.
Liver Transplantation (17)2 2011
Abstract
Abstract
Abstract
Vascularized bone grafting is a useful method for repairing critical bone defects. The repaired bone often presents compromised mechanical strength because of insufficient thickness of the graft. To promote the hypertrophic response, bone morphogenetic protein (BMP) with osteoinductive capacity may...
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PMID: 21200204
PDF is available here.
PDF is available here.
Neurology India (59)3 2011
Abstract
Our study shows that Annexin V-CdTe-conjugated polymer can differentiate the motor and sensory nerve fascicles of the peripheral nerve rapidly and precisely in vitro. This technique represents a new method for the identification of peripheral nerve fascicles....
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PMID: 21743158
PDF is available here.
PDF is available here.
Abstract
The standard technique for securing the base of the appendix during laparoscopic appendectomy is by absorbable endoloop ligature, although clinical reports favor the use of the stapler. Nonabsorbable Hem-o-lok clips have been shown to be an alternative technique to this. However, it is currently not...
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PMID: 21902947
PDF is available here.
PDF is available here.
Abstract
Immunohistochemical techniques detect antigens in tissue sections by means of immunological and chemical reactions. This technique is highly sensitive and specific and can detect a wide variety of antigens in multiple animal species. This chapter reviews common immunohistochemical methods used in th...
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PMID: 20972748
PDF is available here.
PDF is available here.
Abstract
The production of user-defined 3D microstructures from biocompatible and biodegradable materials via free-form fabrication is an important step to create off-the-shelf technologies to be used as tissue engineering scaffolds. One method of achieving this is the microstereolithography of block copolym...
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PMID: 21042980
PDF is available here.
PDF is available here.
Abstract
We describe a method for imaging the position of nanoparticles within a 3D tissue-engineered model using confocal laser scanning microscopy (CLSM). The ability to track diffusion of nanoparticles in vitro is an important part of trans-dermal and trans-mucosal drug delivery development as well as for...
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PMID: 21042964
PDF is available here.
PDF is available here.
Abstract
These results particularly reveal the importance of the proposed modification for the evaluation of low adsorbing substrates and antifouling coatings.
Published by Elsevier B.V....
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PMID: 20833003
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)1 2011
Abstract
Repair of load-bearing defects resulting from disease or trauma remains a critical barrier for bone tissue engineering. Calcium phosphate (CaP) scaffolds are among the most extensively studied for this application. However, CaPs are reportedly too weak for use in such defects and, th...
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PMID: 20655397
PDF is available here.
PDF is available here.
Abstract
We have developed an expanded polytetrafluoroethylene polymer (e-P) coated with both poly-amino-acid urethane copolymer and collagen (e-PPC) to be used for cell culture substrata. Rat mesenchymal stem cells (MSC) were cultured on the e-P and e-PPC polymers in the presence of dexamethasone. After 24...
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PMID: 20695773
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)1 2011
Abstract
Electrospun poly(lactic acid) (PLLA) nanofibers (NF) were modified with cationized gelatin (CG) to improve their compatibility with chondrocytes and to show in vitro and in vivo the potential applications of CG-grafted PLLA nanofibrous membranes (CG-PLLA NFM) as a cartilage tissue en...
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PMID: 20728584
PDF is available here.
PDF is available here.
Abstract
Spontaneous formation of endothelial tubules was restricted to patterned micron-scale regions presenting cell adhesion ligands and angiogenic signaling protein on poly(ethylene glycol) hydrogels. Arginine-glycine-aspartic acid-serine (RGDS), an integrin ligand, and vascular endotheli...
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PMID: 20712418
PDF is available here.
PDF is available here.
Abstract
A promising approach to bone tissue engineering lies in the use of perfusion bioreactors where cells are seeded and cultured on scaffolds under conditions of enhanced nutrient supply and removal of metabolic products. Fluid flow alterations can stimulate cell activity, making the eng...
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PMID: 20872752
PDF is available here.
PDF is available here.
Abstract
A fundamental component of bone tissue engineering is an appropriate scaffold as a carrier for osteogenic cells. The aim of the study was to evaluate the response of human bone marrow stromal cells (BMSC) to scaffolds made of three biodegradable polymers: poly(L-lactide-co-ε-caprola...
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PMID: 20939051
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
Mixed-scale nano- and microfluidic networks were fabricated in thermoplastics using simple and robust methods that did not require the use of sophisticated equipment to produce the nanostructures. High-precision micromilling (HPMM) and photolithography were used to generate mixed-scale molding tools...
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PMID: 20938506
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
A direct molding method for creating a homogeneous, polymer microfluidic channel is presented. By utilizing capillary rise and subsequent absorption of poly(methyl methacrylate) (PMMA) solution into a solvent-permeable poly(dimethyl siloxane) (PDMS) mold, various circular or elliptic polymer microch...
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PMID: 20938498
PDF is available here.
PDF is available here.
Abstract
We report a polycationic polymer MRI contrast agent that binds to DNA in a ratio of one monomer unit per phosphate group of DNA. Significantly, this binding event diminishes the MR contrast signal from the agent itself potentially providing a platform for imaging delivery and release of a gene into...
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PMID: 20848030
PDF is available here.
PDF is available here.
Abstract
Bionic limbs require sensitive, durable, and physiologically relevant bidirectional control interfaces. Modern central nervous system interfacing is high risk, low fidelity, and failure prone. Peripheral nervous system interfaces will mitigate this risk and increase fidelity by greatly simplifying s...
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PMID: 20700080
PDF is available here.
PDF is available here.
Abstract
Among the treatment options that have been developed for cancer, chemotherapy remains 1 of the leading clinical approaches. Chemotherapy can usually control tumor growth at the onset of disease, but its effectiveness becomes limited by the overexpression of transporter proteins respo...
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PMID: 20715163
PDF is available here.
PDF is available here.
Abstract
Two alginate lyase isozymes, AkAly28 and AkAly33, with approximate molecular masses of 28 and 33kDa, respectively, were isolated from the digestive fluid of the common sea hare, Aplysia kurodai. Both of AkAly28 and AkAly33 were regarded as the endolytic polymannuronate (poly(M)) lyase (EC 4.2.2.3) s...
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PMID: 20708706
PDF is available here.
PDF is available here.
Marine Pollution Bulletin (60)12 2010
Abstract
Samples from nine Central Vietnam coastal lagoons, together with three soils and sediments collected in two freshwater reservoirs of the Thua Thien-Hué province, were analysed for polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). Total concentrations are low, from 192 to 2912 pg g(-1)...
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PMID: 20952038
PDF is available here.
PDF is available here.
Evaluation of dense polylactic acid/beta-tricalcium phosphate scaffolds for bone tissue engineering.
Abstract
We investigated the microstructural and mechanical properties of dense PLA and PLA/beta-TCP (85:15) scaffolds fabricated using a rapid volume expansion phase separation technique, which embeds uncoated beta-TCP particles within the porous polymer. PLA scaffolds had a volumetric porosity in the range...
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PMID: 20725979
PDF is available here.
PDF is available here.
Journal of Chromatography A (1217)48 2010
Abstract
We have investigated the free-radical copolymerization dynamics of styrene and divinylbenzene in the presence of micro- and macro-porogenic diluents in 100 μm I.D. sized molds under conditions of slow thermal initiation leading to (macro)porous poly(styrene-co-divinylbenzene) monolithic scaffolds....
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PMID: 20980011
PDF is available here.
PDF is available here.
Lab On a Chip (10)22 2010
Abstract
We report a mechanistic study of how flow and recirculation in a microreactor can be used to optimize the capture and release of stimuli-responsive polymer-protein reagents on stimuli-responsive polymer-grafted channel surfaces. Poly(N-isopropylacrylamide) (PNIPAAm) was grafted to polydimethylsiloxa...
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PMID: 20882219
PDF is available here.
PDF is available here.
Abstract
The crystal structure of the neuropeptide proctolin (Arg-Tyr-Leu-Pro-Thr) is reported revealing the solid-state conformation of its molecules and their association in the crystal.
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PMID: 20838690
PDF is available here.
PDF is available here.