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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Cartilage Diseases (6):
Recent article
Cartilage Diseases
Clinical calcium (20)10 2010
Abstract
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Ugeskrift for laeger (172)38 2010
Abstract
Mesenchymal stem cells (MSC) are capable of multilineage differentiation into cells like osteoblasts, chondrocytes or adipocytes. MSCs can be isolated from bone marrow and expanded ex vivo for up to 25-40 population doublings while maintaining genetic stability and differentiation potential. MSCs ha...
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PMID: 20920407
PDF is available here.
PDF is available here.
Orthopedics (33)9 2010
Abstract
The causes of persistent wrist pain following carpal tunnel release include scar tenderness and pillar pain. The goal of this study was to evaluate latent pisotriquetral arthrosis as a source of ulnar-sided wrist pain following open carpal tunnel release. Seven hundred consecutive carpal tunnel rele...
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PMID: 20839709
PDF is available here.
PDF is available here.
Abstract
Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to protect the central nervous system, to find new clues about local anesthetic effects in chronic neuropathic pain, and to investigate the long-term effect of anesthesia/analge...
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PMID: 20610984
PDF is available here.
PDF is available here.
Abstract
These results document a dramatic age-related decline in human chondrocyte chondrogenic potential and show that allogeneic juvenile chondrocytes do not stimulate an immunologic response in vivo.
Juvenile human chondrocytes have greater potential to restore articular cartilage than ad...
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PMID: 20423988
PDF is available here.
PDF is available here.
Zhonghua Yixue Zazhi (90)25 2010
Abstract
To compare several sequences of MRI and arthroscopy for detecting the ankle articular cartilage lesions and to evaluate the clinical outcome of special sequence of FS-3D-FISP.
Forty patients (41 ankles) with iterative ankle pain who were scheduled for arthroscopy underwent MR scanning, including FS-...
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PMID: 20979892
PDF is available here.
PDF is available here.
European Radiology (20)6 2010
Abstract
Mean T2 values (ms) were comparable for the control cartilage (53.4 +/- 11.7) and the repair tissue (55.5 +/- 11.6) (p > 0.05). Mean T2* values (ms) for control cartilage (30.9 +/- 6.6) were significantly higher than those of the repair tissue (24.5 +/- 8.1) (p < 0.001). Zonal stratification was mor...
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PMID: 19937329
PDF is available here.
PDF is available here.
Skeletal Radiology (39)6 2010
Abstract
In the hips after SCFE alpha angles were significantly increased in the anterosuperior (74.1 degrees +/- 18.8 degrees ) and superior (72.5 degrees +/- 21.5 degrees ) positions and decreased in the posterior position (25.0 degrees +/- 7.2 degrees ). Cartilage damage was dominant in the anterosuperior...
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PMID: 20177672
PDF is available here.
PDF is available here.
Skeletal Radiology (39)6 2010
Abstract
The results of this study suggest a local spatial correlation between BMELs and more advanced and accelerated cartilage degeneration. MRI T(1rho) quantification in cartilage provides a sensitive tool for evaluating such correlations....
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PMID: 20195865
PDF is available here.
PDF is available here.
Abstract
Laser arytenoidectomy is effective for improving the breathing in children presenting with a bilateral vocal fold paralysis associated with obstructive arytenoid prolapse. Results are good as a first-line surgery or following laryngo-tracheal surgery. Voice outcomes are satisfactory. However, aspira...
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PMID: 20163880
PDF is available here.
PDF is available here.
Abstract
There was a significant difference (p < 0.01) between the patients' preoperative and postoperative pain and activity abilities as measured with the Foot Function Index and AOFAS Ankle-Hindfoot questionnaires. Clinical examination and X-rays confirmed healing of the graft. CONCLUSION: Based on these...
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PMID: 20371012
PDF is available here.
PDF is available here.
Abstract
Mean OMAS improved from 28 to 71 points (p < 0.05). Three had further surgery; overall graft survival rate was 10/12. Of surviving grafts, 30% recorded excellent (OMAS: 100 to 91 points), 20% good (OMAS: 90 to 61 points), 30% fair (OMAS: 60 to 31 points), and 20% poor (OMAS: 30 to 0 points) outcomes...
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PMID: 20371013
PDF is available here.
PDF is available here.
Abstract
Although we cannot establish a causal link, the development of glenohumeral chondrolysis may be related to the intra-articular infusion of bupivacaine with epinephrine postoperatively. We thus caution against the use of IAPPCs. LEVEL OF EVIDENCE: Level IV, therapeutic case series.
Copyright 2010 Art...
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PMID: 20362823
PDF is available here.
PDF is available here.
Abstract
Abstract
By using the z test to compare parameters between methods, the respective sensitivity, specificity, and accuracy for detecting all 192 cartilage lesions were 68.5%, 92.6%, and 84.5% for IDEAL GRASS and 66.1%, 92.9%, and 83.9% for the routine MR protocol. There was no significant difference (P = .34-...
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PMID: 20173102
PDF is available here.
PDF is available here.
Abstract
We report a case of distal femoral varus deformity secondary to FFCD. Spontaneous resolution of the deformity occurred during a 7-year period. Previous reported femoral cases showed progressive deformity and required treatment with soft-tissue releases with or without osteotomy. This is the first re...
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PMID: 20051915
PDF is available here.
PDF is available here.
Abstract
The objective of this study was to investigate the changes in synovial fluid concentration of collagen type II cleavage site (C2C) and procollagen II C-propeptide (CPII), markers of joint cartilage degeneration and synthesis, respectively, in horses with intraarticular fracture or osteochondrosis di...
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PMID: 20364792
PDF is available here.
PDF is available here.
Hip International (20)1 2010
Abstract
We report 19 consecutive patients in whom the delaminated chondral flap was re-attached to the underlying subchondral bone with fibrin adhesive. We used the modified Harris hip score for assessment of pain and function. Improvement in pain and function was found to be statistically significant six m...
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PMID: 20235074
PDF is available here.
PDF is available here.
Abstract
The current approaches to treating articular cartilage defects in the knee comprise a spectrum from pharmacologic therapies to total knee arthroplasty. Nonsurgical treatment can include anti-inflammatory medications, bracing, and physical therapy. Surgical treatments include reconstructive repair of...
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PMID: 20415378
PDF is available here.
PDF is available here.
Abstract
The treatment of isolated cartilage lesions of the knee is based on several underlying principles, including a predictable reduction in the patient's symptoms, improvements in function and joint congruence, and prevention of progressive damage. Surgical options for cartilage restoration are describe...
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PMID: 20415379
PDF is available here.
PDF is available here.
Abstract
Injuries to articular cartilage are one of the most challenging issues of musculoskeletal medicine due to the poor intrinsic ability of this tissue for repair. Despite progress in orthopaedic surgery, the lack of efficient modalities of treatment for large chondral defects has prompt...
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PMID: 19804369
PDF is available here.
PDF is available here.
Orvosi Hetilap (150)47 2009
Abstract
Kissing surface type defects of the cartilage represent a special category in cartilage diseases. They are characteristics for more difficult treatment, more compromises and moderate results. The authors adopted mosaicplasty technique for full thickness cartilage defects. According to their early ex...
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PMID: 19910281
PDF is available here.
PDF is available here.
Abstract
OBJECTIVE: To describe a new treatment for perichondritis and haematoma of the pinna. At present, the existing treatment for these conditions is initially medical (which usually fails), followed by surgery (incision, drainage and compression to prevent recurrence) with accompanying medical managemen...
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PMID: 19566972
PDF is available here.
PDF is available here.
Abstract
Lesions in articular cartilage can result in significant musculoskeletal morbidity and display unique biomechanical characteristics that make repair difficult, at best. Several surgical procedures have been devised in an attempt to relieve pain, restore function, and delay or stop the progression of...
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PMID: 19786989
PDF is available here.
PDF is available here.
Subtotal or partial unilateral arytenoidectomy for treatment of arytenoid chondritis in five calves.
Abstract
Tachypnea and inspiratory dyspnea were detected at initial evaluation in all calves. Endoscopic evaluation of the upper respiratory tract revealed enlarged and immobile arytenoids. Radiographic (n = 3) and computed tomographic (1) evaluation of the laryngeal area revealed images that were indicative...
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PMID: 19681726
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe a new technique that may be applied for harvesting bone marrow cells from cartilage defects during arthroscopic intervention of the knee. Cells harvested in this way hold full chondrogenic differentiation potential. Our data imply that MSC storage may be established by using marrow from...
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PMID: 19662475
PDF is available here.
PDF is available here.
Abstract
We review the current morphological imaging methods and the biochemical MRI techniques to assess the cartilage. We then illustrate the application of these MRI sequences for the most common degenerative and traumatic disorders affecting lower limb cartilage....
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PMID: 20410805
PDF is available here.
PDF is available here.
Abstract
A wide range of gross defects was detected in the cartilage on the opposing surfaces of the bones of the midcarpal joint; however, there was no significant difference between the CONDEX and PASTEX groups. Similarly, no significant difference in swelling behavior of the cartilage ECM was evident betw...
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PMID: 19405897
PDF is available here.
PDF is available here.
Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Journal of Reparative and Reconstructive Surgery (23)4 2009
Abstract
Western blot test showed the expression of the hTGF-beta1, Col II and the Aggrecan in the hTGF-beta1 transduction group were significantly higher than that of the Adv-betagal transduction and the blank control groups. All the goats survived until the end of experiment and all the wounds healed by fi...
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PMID: 19431993
PDF is available here.
PDF is available here.
Abstract
Joint immobilization is commonly used for the treatment of joint injuries and diseases, but it also causes cartilage degeneration. Damage to the fibrillar meshwork of type II collagen in the articular cartilage is a critical event for cartilage degeneration. Collagenases such as matrix metalloprotei...
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PMID: 19346731
PDF is available here.
PDF is available here.
Abstract
We report middle-aged male monozygotic twins who simultaneously developed CNCH. This suggests, but does not prove, the possibility of a hereditary factor in the pathogenesis of CNCH....
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PMID: 19175786
PDF is available here.
PDF is available here.
Abstract
Cloning and Stem Cells (11)1 2009
Abstract
These results showed that HAMc have the potential to differentiate into chondrocytes in vitro and in vivo, suggesting that they have therapeutic potential for the treatment of damaged or diseased cartilage....
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PMID: 19226212
PDF is available here.
PDF is available here.
Abstract
Abstract
To diagnose meniscal tears, statistical agreement measure for MRI with arthroscopy was good (K=0.69) but not as good as the MR-arthrography/arthroscopy agreement which, by itself was excellent (K=0.84). As a diagnosis tool, the sensitivity and specificity of MR-arthrography (respectively 100 and 89....
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PMID: 19251236
PDF is available here.
PDF is available here.
Abstract
Of the 250 analysed charts, 72 patients (28.8%) were found to present chondral patella lesions. The majority of these lesions were superficial and involved the lateral facet area. We observed a statistically significant ICRS worsening grade in relation to laxity duration. DISCUSSION: Few publication...
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PMID: 19251235
PDF is available here.
PDF is available here.
Abstract
Magnetic resonance imaging remains the only non-invasive method to assess the quality of cartilage repair procedures, but ideally would be complemented by other modalities, particularly blood tests. Nganvongpanit and colleagues investigated serum levels of hyaluronic acid (HA) and chondroitin sulfat...
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PMID: 19591657
PDF is available here.
PDF is available here.
Hip International (19)1 2009
Magnetic resonance imaging with gadolinium arthrography to assess acetabular cartilage delamination.
Abstract
Recent reports have demonstrated magnetic resonance imaging (MRI) as a promising technique in detecting articular cartilage lesions of the hip joint. The purpose of our study was to evaluate the diagnostic performance of MRI with gadolinium arthrography in detecting acetabular cartilage delamination...
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PMID: 19455497
PDF is available here.
PDF is available here.
Abstract
An adult, Japanese domestic cat presented with bilateral swelling, distortion, and erythema of ears and deformation of the limbs. Biopsy of the pinnae confirmed auricular chondritis. These lesions and the cat's general condition subsequently deteriorated, and the cat died. At necropsy, chondral chan...
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PMID: 19194079
PDF is available here.
PDF is available here.
Orthopedics (32)1 2009
Abstract
I error rate of 0.0024 (0.05/21) was adopted to indicate statistical significance. Based on examination of the patellofemoral anatomy, 4 parameters were significantly associated with patellofemoral cartilage lesions. These were the patella lateral facet width, patella lateral facet ratio, sulcus dep...
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PMID: 19226043
PDF is available here.
PDF is available here.
Abstract
Abstract
The female predisposition toward knee OA may, at least in part, be due to gender differences in cartilage health, even before the onset of clinical knee disease. Understanding the mechanism for these gender differences may provide a means to reduce the risk of knee OA in women....
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PMID: 19598333
PDF is available here.
PDF is available here.
Abstract
Abstract
Articular cartilage injury is observed with increasing frequency in both elite and amateur athletes and results from the significant joint stress associated particularly with high-impact sports. The lack of spontaneous healing of these joint surface defects leads to progressive joint pain and mechan...
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PMID: 19064163
PDF is available here.
PDF is available here.
Abstract
We previously reported a noncontact ultrasound water jet indentation system for measuring and mapping tissue mechanical properties. The key idea was to utilize a water jet as an indenter as well as the coupling medium for high-frequency ultrasound. In this paper, the system was employed to assess ar...
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PMID: 19011965
PDF is available here.
PDF is available here.
Abstract
Osteoarthritis (OA) is a prevalent degenerative joint disease that places a significant burden on the socioeconomic efficacy of communities around the world. Tissue engineering repair of articular cartilage in synovial joints represents a potential OA treatment strategy superior to c...
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PMID: 18844605
PDF is available here.
PDF is available here.
Abstract
Osteoarthritis (OA) is a prevalent degenerative joint disease that places a significant burden on the socioeconomic efficacy of communities around the world. Tissue engineering repair of articular cartilage in synovial joints represents a potential OA treatment strategy superior to current surgical...
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PMID: 18844605
PDF is available here.
PDF is available here.
Abstract
The effect of water extracts of Euphorbia hirta on the histological features and expressions of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the rat articular cartilage was investigated. Arthritis was induced in rats using Freund's Complete Adjuvant...
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PMID: 19291918
PDF is available here.
PDF is available here.
Abstract
In recent years, regenerative techniques, such as autologous chondrocyte implantation (ACI), have emerged as a potential therapeutic option for the treatment of chondral lesions. However, the good results reported have to be weighed against the number of problems that can be observed with traditiona...
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PMID: 19011554
PDF is available here.
PDF is available here.
Abstract
Minced articular cartilage procedures are attractive surgical approaches for repairing articular cartilage, as they are 1-staged, autologous, and inserted on a carrier that can potentially be placed arthroscopically. The principle of mincing the autologous donor cartilage is to create a larger surfa...
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PMID: 19011553
PDF is available here.
PDF is available here.
Abstract
Currently, autologous chondrocyte implantation and osteochondral grafting bridge the gap between palliation of cartilage injury and resurfacing via arthroplasty. Emerging technologies seek to advance first generation techniques and accomplish several goals including predictable outcomes, cost-effect...
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PMID: 19011550
PDF is available here.
PDF is available here.
Abstract
Magnetic resonance imaging is an important noninvasive modality in characterizing cartilage morphology, biochemistry, and function. It serves as a valuable objective outcome measure in diagnosing pathology at the time of initial injury, guiding surgical planning, and evaluating postsurgical repair....
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PMID: 19011556
PDF is available here.
PDF is available here.
Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Journal of Reparative and Reconstructive Surgery (22)12 2008
Abstract
At 4-8 weeks postoperatively, in the experimental group, the defects were filled with hyaline cartilage-like tissues; the majority of chitosan degradated; and the DBM particles were partly absorbed. However, in the control group, there were small quantities of discontinuous fibrous tissues and maldi...
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PMID: 19137897
PDF is available here.
PDF is available here.
Osteoarthritis and Cartilage (16)12 2008
Abstract
Unstimulated periosteal cells formed a fibrous extracellular matrix in the superficial zone and a fibrocartilaginous matrix in deep zones of the repair tissue. This zonal difference was reflected by the absence of HIF-1alpha staining in superficial areas, but moderate HIF-1alpha expression in deep z...
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PMID: 18524637
PDF is available here.
PDF is available here.
Abstract
Various treatment options for deep cartilage defects are presently available. The efficacy of bone marrow stimulation with microfracture, of mosaicplasty and of various autologous chondrocyte implantation (ACI) techniques has been subject to numerous studies recently. Magnetic resonance imaging (MRI...
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PMID: 19016394
PDF is available here.
PDF is available here.
Journal de Radiologie (89)12 2008
Abstract
Abstract
All 12 patients had significant immune abnormalities, leading to severe immune deficiency in 9. CD8 lymphocytopenia was identified as a novel phenotype associated with RMRP mutations. Significant, even intrafamilial, phenotypic heterogeneity was observed. In 3 cases, severe immunodeficiency was the...
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PMID: 18804272
PDF is available here.
PDF is available here.
Abstract
A total of 56 patients > or =45 years of age were treated with ACI. The average patient age at index surgery was 48.6 years (range, 45-60 years). The minimum follow-up was 2 years (range, 2-11 years; mean, 4.7 years). The cohort included 36 men and 20 women. The mean transplant size was 4.7 cm(2) pe...
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PMID: 18725654
PDF is available here.
PDF is available here.
Abstract
Matrix-associated autologous chondrocyte transplantation (MACT) is a tissue-engineered approach for the treatment of cartilage defects and combines autologous chondrocytes seeded on biomaterials. The objective of the study is the analysis of growth and differentiation behaviour of human articular ch...
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PMID: 18949392
PDF is available here.
PDF is available here.