Abstract
We review recent studies exploring the role of DNA methylation in these critical processes. Further, we suggest that, perhaps, the adult brain controls and utilizes the mechanism of DNA methylation in non-traditional ways that are waiting to be explored....
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PMID: 21527830
PDF is available here.
Abstract
We estimated the extent to which dimensions of romantic attachment and negative emotionality share genetic or environmental risk factors in 1,237 middle-aged men in the Vietnam Era Twin Study of Aging (VETSA). A common genetic factor largely explained the covariance between attachment-related anxiet...
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PMID: 21213033
PDF is available here.
Abstract
We encourage the use of our site for both scientific discovery and as a teaching tool in quantitative genetics....
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PMID: 21184165
PDF is available here.
Abstract
We pose that it is essential that the goal of the specific experiment conducted is clearly defined and that the decision to balance between standardization and generalization must be made based on the specific needs to meet the intended goal. In this light, we discuss a multi-tiered approach to anim...
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PMID: 20662940
PDF is available here.
Abstract
Inhibitory control (IC) is a dimension of child temperament that emerges in toddlerhood and involves the ability to regulate behavior in response to instructions or expectations. In general, children with low levels of IC have more cognitive and social difficulties, and higher levels of problem behav...
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PMID: 19936910
PDF is available here.
Abstract
We conduct a two-stage analysis to examine these inferences in a time-ordered multivariate context. First, using data from the National Longitudinal Survey of Youth, 1979, and LISREL analysis, we develop a structural equation model in which five hypothesized motivational precursors to fertility, mea...
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PMID: 20608103
PDF is available here.
Abstract
The most recent National Occupational Research Agenda includes, as a goal, conducting research that enhances the understanding of psychological factors that affect the well-being of people engaged in farming. The author proposes a construct, the agrarian imperative, as an explanation for why people...
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PMID: 20407984
PDF is available here.
Abstract
We summarize some of the recent molecular genetics work concerning antisocial spectrum disorders and psychopathy, with a focus on genes involved in the serotonergic and dopaminergic pathways, while also mentioning some of the novel genetic factors being considered. Monoamine oxidase (MAOA) and the s...
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PMID: 20422643
PDF is available here.
Abstract
Rats selectively bred based on high or low reactivity to a novel environment were characterized for other behavioral and neurobiological traits thought to be relevant to addiction vulnerability. The two lines of animals, which differ in their propensity to self-administer drugs, also differ in the v...
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PMID: 19794408
PDF is available here.
Feng F Li,
Yiping Y Shen,
Udo U Köhler,
Freddie H FH Sharkey,
Deepa D Menon,
Laurence L Coulleaux,
Valérie V Malan,
Marlène M Rio,
Dominic J DJ McMullan,
H H Cox,
Kerry A KA Fagan,
Lorraine L Gaunt,
Kay K Metcalfe,
Uwe U Heinrich,
Gordon G Hislop,
Una U Maye,
Maxine M Sutcliffe,
Bai-Lin BL Wu,
Brian D BD Thiel,
Surabhi S Mulchandani,
Laura K LK Conlin,
Nancy B NB Spinner,
Kathleen M KM Murphy and
Denise A S DA Batista
Abstract
We report 29 individuals with the microduplication found as part of microarray analysis of 7793 samples submitted to an international group of 13 clinical laboratories. The referral reasons varied and included developmental delay, intellectual disability, autism, dysmorphic features and/or multiple...
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PMID: 20132918
PDF is available here.
Abstract
We illustrate how these diverging interpretations result in radically different views on the identity of psychiatry and its relationship with the rapidly expanding domain of neurology/neuroscience....
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PMID: 21037408
PDF is available here.
Abstract
We understand metahistory as an approach that studies how histories within a particular discipline have been written and focus on insider scientists' reconstructions of twin research. Using the concept of ethical-political affordances we suggest that such histories are based on a management of resou...
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PMID: 20419900
PDF is available here.
Abstract
The past two decades have seen an explosion in research in the fields of violence and behavioural genetics. Advances in human genetics have raised the possibility that genetic mechanisms can explain various aspects of human criminal and aggressive behaviour. However, this new knowledge can pose enor...
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PMID: 20025103
PDF is available here.
Abstract
Genetic factors have long been recognized as contributors to variantion in behaviour both within the normal span and as mental diseases. The first attempts to make behaviour the subject of scientific genetic studies used likeness between twins and other relatives to confirm heredity. Later heritabil...
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PMID: 19891739
PDF is available here.
Abstract
This study investigated the possible effects of genetic and environmental gender differences in effect on individual differences by using the Bem Sex Role Inventory (BSRI) with twins. A sex/gender-limitation analysis, a behavior genetics methodology was used to the following: (a) effects of gender-s...
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PMID: 19938658
PDF is available here.
Abstract
Evolutionary psychologists explore the adaptive function of traits and behaviors that characterize modern Homo sapiens. However, evolutionary psychologists have yet to incorporate the phylogenetic relationship between modern Homo sapiens and humans' hominid and pongid relatives (both living and exti...
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PMID: 19702384
PDF is available here.
Abstract
Although there are significant intra-individual differences in self-reported diurnal preference, as measured by validated questionnaires, the relative contribution of exogenous and endogenous factors to self-reported diurnal preference largely remains to be investigated. The present study examined wh...
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PMID: 19360490
PDF is available here.
Abstract
The biopsychosocial perspective is a foundation of social work theory and practice. Recent research on neuroplasticity and psychosocial genomics lends compelling support to this perspective by elucidating mechanisms through which psychosocial forces shape neurobiology. Investigations of neuroplastic...
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PMID: 19728478
PDF is available here.
Abstract
The concept of memes is analyzed, and its applicability to suicidology explored. Proposals are made for possible memes implicated in suicidal behavior. A classification of suicidal memes is proposed and the relationship between memes and archetypes of suicide is discussed. It is suggested that the t...
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PMID: 19810429
PDF is available here.
Abstract
The Swiss sublines of Roman High-(RHA/Verh) and Low-(RLA/Verh) Avoidance rats have been genetically selected (and outbred) since 1972 because of their good versus extremely poor acquisition of two-way, active avoidance. Inbred strains (RHA-I and RLA-I), derived from those two lines, have been mainta...
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PMID: 19178852
PDF is available here.
Abstract
The literature is unanimously advocating a dimensional concept of personality disorders. Four dimensions are consistently reported to underlie personality disorder symptoms. We put forward an argument that personality disorders are disorders of adaptation, not of personality per se, as extreme perso...
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PMID: 19122542
PDF is available here.
Abstract
I intend to argue that sociological theories may broaden their scope of analysis by encompassing biological dimensions, which does not necessarily mean adopting a biological reductionist approach....
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PMID: 19824336
PDF is available here.
Abstract
Modeling both genetic and cultural transmission in parent-offspring data in the presence of phenotypic assortment requires the imposition of nonlinear constraints. This article reports a simulation study that determined how well the structural equation modeling software package Mx and the Bayesian-o...
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PMID: 19020969
PDF is available here.
Abstract
A genetic factor model is introduced for decomposition of group differences of the means of phenotypic behavior as well as individual differences when the research variables under consideration are ordered categorical. The model employs the general Genetic Factor Model proposed by Neale and Cardon (...
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PMID: 19009342
PDF is available here.
Abstract
The field of behavior genetics as an entity developed during the middle of the twentieth century. Developments at the Jackson Laboratory in Bar Harbor, Maine played an important role in this process. The role included an important conference, education and training, research, and publications, inclu...
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PMID: 19020968
PDF is available here.
Abstract
As self-fertilizing nematodes, Caenorhabditis elegans do not normally come to mind when one thinks of social animals. However, their reproductive mode is optimized for rapid population growth, and although they do not form structured societies, conspecifics are an important source of sensory input....
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PMID: 20109657
PDF is available here.
Abstract
Studies of the genetic basis of behaviour in mice are at a turning point. Soon, new resources will enable the behavioural function of all genes to be tested and the networks of genes, messenger RNAs and proteins involved in a particular behaviour to be identified. Using these resourc...
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PMID: 19079048
PDF is available here.
Abstract
A rich line of empirical research has indicated that antisocial behaviors are the result of genetic factors and environmental factors working interactively. The current study uses this knowledge base as a springboard to examine the effects of childhood sexual abuse and genetic risk in the prediction...
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PMID: 18840900
PDF is available here.
Abstract
We assessed salutogenic factors, depression, and quality of life; however, we analyzed the questionnaires completed by the mothers. Statistical analyses were conducted using structural equation modeling. We conclude that nonshared environmental components were of principal importance in individual r...
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PMID: 19130792
PDF is available here.
Abstract
One of the central questions in neuroscience is how refined patterns of connectivity in the brain generate and monitor behavior. Genetic mutations can influence neural circuits by disrupting differentiation or maintenance of component neuronal cells or by altering functional patterns of nervous syst...
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PMID: 18836206
PDF is available here.
Abstract
We introduce and illustrate a new genetically-informative design. First, we develop a kinship linking algorithm, using the NLSY79 and the NLSY-Children data to link mothers to daughters and aunts to nieces. Then we construct mother-daughter correlations to compare to aunt-niece correlations, an MDAN...
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PMID: 18825497
PDF is available here.
Abstract
Nine thousand and three hundred thirty nine pairs of 0-16 years old twins have been registered, 324 pairs of them were monozygotic based on DNA samples as well as the detailed information on behavioral and cognitive aspects.Analysis has been performed for the influences of genetic and environmental...
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PMID: 18841569
PDF is available here.
Abstract
Attachment theory attempts to explain effects of social experiences, not genes, on personality development. Most studies of the development of attachment insecurities support this emphasis on social experiences rather than genes, although there are exceptions. In the present study, the authors exami...
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PMID: 18687882
PDF is available here.
Abstract
We investigated the associations among lifetime gambling-related CDs, psychiatric disorders other than pathological gambling , and problem gambling severity. Subjects were 1354 members of the Vietnam Era Twin Registry. Problem gambling and gambling-related CDs were derived from a 2002 interview usin...
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PMID: 18710784
PDF is available here.
Abstract
We suggest that a potentially important cause of variation in condition is competition for limited resources. Here, we discuss a pair of models to analyze the evolutionary genetics of traits affected by success in social competition for resources. We show that competition can contribute to genetic v...
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PMID: 17924196
PDF is available here.
Abstract
We outline principles for understanding gene epistasis due to signaller-receiver dynamics, gene interactions between individuals, and impacts on life history trade-offs. Signaller-receiver epistases create trade-offs among multiple correlated traits that affect fitness, and generate multiple fitness...
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PMID: 18685573
PDF is available here.
Abstract
The best-fit model indicated an active developmental relationship between CD and PD including forward transmission of both traits over time and strong causal relationships between CD and PD within time periods. The best-fit model indicated that the causal relationship for genetic risk factors was fr...
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PMID: 17935643
PDF is available here.
Abstract
The Kraepelinian classification of psychiatric disorders, in particular the dichotomy of dementia praecox and manic-depressive psychosis is under discussion since a long time. In recent years, not only new research in the fields of psychopathology and clinical outcome, but also findings of biologica...
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PMID: 18516521
PDF is available here.
Abstract
We administered the Anxiety Sensitivity Index to 245 monozygotic and 193 dizygotic twin pairs, comprising 658 women and 218 men. Scores were calculated for the most widely replicated AS dimensions; physical, cognitive, and social concerns. For women, each dimension was influenced by a combination of...
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PMID: 18029140
PDF is available here.
Abstract
This article addresses a question at the juncture of neurophysiology and neurogenetics--the role of the brain neurotransmitter serotonin in the genetic control of behavior. Published data are presented, along with results obtained from studies performed at the Behavioral Neurogenomics Laboratory. Th...
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PMID: 18607754
PDF is available here.
Abstract
We examine what went wrong in the dissemination of the research. We chose as our framework the debate around the "internal/external" responsibilities of scientists. Using this discourse we argue that when the researchers ventured to explain their research in terms of social phenomena, they assumed a...
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PMID: 18511629
PDF is available here.
Abstract
We study the co-evolution of culturally inherited altruistic helping behaviors and two alternative cultural transmission rules for such behaviors. We find that conformist transmission, where individuals within groups tend to copy prevalent cultural variants (e.g., beliefs or values), has a strong ad...
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PMID: 18420241
PDF is available here.
Abstract
Results indicate that the likelihood of having a physical condition is related to higher levels of prior neuroticism, with some associations attenuated when controlling for familial similarity. CONCLUSION: Familial influences are most pronounced for conditions most related to systemic pain, suggesti...
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PMID: 18624602
PDF is available here.
Abstract
Few parents of a teenager are surprised to hear that the brain of a 16-year-old is different from the brain of an 8-year-old. Yet to pin down these differences in a rigorous scientific way has been elusive. Magnetic resonance imaging, with the capacity to provide exquisitely accurate quantifications...
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PMID: 18346658
PDF is available here.