Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Immunogenetics (0):
Recent article
Immunogenetics
Transplant International (24 Suppl 2) 2011
Abstract
| < More recent | Older article > |
Autoimmunity Reviews (10)5 2011
Abstract
We are currently reaching a period of rapid data production. Several themes are already rising from the first wave of results. First, some genetic variants clearly predispose to multiple autoimmune diseases, thus providing evidence for a shared autoimmune genetic background. Second, multiple genes a...
|
PMID: 20863905
PDF is available here.
PDF is available here.
Abstract
The DSA strength correlates well with crossmatch results. An MFI of 6540 predicted a positive antihuman globulin T-cell crossmatch....
|
PMID: 20923311
PDF is available here.
PDF is available here.
Abstract
During the 15th International Histocompatibility and Immunogenetics Workshop (IHIWS), 14 human leukocyte antigen (HLA) laboratories participated in the Analysis of HLA Population Data (AHPD) project where 18 new population samples were analyzed statistically and compared with data available from pre...
|
PMID: 20331842
PDF is available here.
PDF is available here.
Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine (15 Suppl 8) 2009
Abstract
médecine/sciences (25)12 2009
Abstract
IMGT, the international ImMunoGeneTics information system, was created in 1989 in Montpellier by the Laboratoire d'ImmunoGénétique Moléculaire (LIGM) headed by the Professors Marie-Paule and Gérard Lefranc (University Montpellier 2 and CNRS). IMGT is specialized in the sequences, structures and...
|
PMID: 20035673
PDF is available here.
PDF is available here.
Deutsche Medizinische Wochenschrift (134)34/35 2009
Abstract
Managed care (Langhorne, Pa.) (18)4 Suppl 3 2009
Abstract
Abstract
The aim of this review is to present a concise overview of all data available on the immunogenetics of Chlamydia trachomatis infections, both sexually transmitted urogenital and ocular infections. Currently, candidate gene approaches are used to identify genes related to the susceptibility to and se...
|
PMID: 19170753
PDF is available here.
PDF is available here.
Cancer Research (68)24 2008
Abstract
I receptor kinase inhibitor SM16. Adenovirus expressing IFN-beta (Ad.IFN-beta) was injected intratumorally once in established s.c. AB12 (mesothelioma) and LKR (lung cancer) tumors or intratracheally in a Kras orthotopic lung tumor model. Mice bearing TC1 (lung cancer) tumors were vaccinated with tw...
|
PMID: 19074893
PDF is available here.
PDF is available here.
Abstract
We demonstrate associations between genetic variations (single nucleotide polymorphisms, SNPs) in HLA class I and class II genes, cytokine, cell surface receptor, and toll-like receptor genes and variations in immune responses to measles vaccine. Such information may provide further understanding of...
|
PMID: 18598732
PDF is available here.
PDF is available here.
Acta Microbiologica Sinica (48)11 2008
Abstract
We tested the antigenicity of porcine rotavirus Vp7 gene expressed in Lactobacillus. METHODS: We studied the condition of electroporation and transformed the plasmid pW425et-Vp7 into thyA gene-mutant L. acidlophilus. Then the positive clone was selected and its expression was detected by SDS-PAGE an...
|
PMID: 19149168
PDF is available here.
PDF is available here.
Abstract
I epitopes, and the presence of haplotype mismatching. When cord blood transplantation is an option, both cell dose and HLA matching are important variables. Optimizing the overall outcome of hematopoietic cell transplantation requires an appreciation for the relative importance of HLA factors with...
|
PMID: 18674615
PDF is available here.
PDF is available here.
médecine/sciences (24)10 2008
Abstract
Abstract
Abstract
Abstract
Recent advances in immunological and genetic research in coeliac disease provide new and complementary insights into the immune response driving this chronic intestinal inflammatory disorder. Both approaches confirm the central importance of T cell-mediated immune responses to disease pathogenesis a...
|
PMID: 18713140
PDF is available here.
PDF is available here.
Journal of Immunology (181)3 2008
Abstract
We wish to emphasize that the recent knowledge in understanding the capacities of an APC to handle an Ag and the importance of the surrounding microenvironment in this process are crucial for designing novel protein therapeutics with reduced immunogenicity....
|
PMID: 18641295
PDF is available here.
PDF is available here.
American Journal of Health-System Pharmacy (65)14 Suppl 6 2008
Abstract
PURPOSE: Scientific issues and clinical implications associated with the use of biosimilars (biopharmaceuticals that are similar to an innovator product, notwithstanding minor differences) are illustrated in two examples, botulinum neurotoxins and erythropoietic agents. SUMMARY: Comparison of Botox...
|
PMID: 18591714
PDF is available here.
PDF is available here.
Abstract
IMGT, the international ImMunoGeneTics information system (http://imgt.cines.fr), is the reference in immunogenetics and immunoinformatics. IMGT standardizes and manages the complex immunogenetic data that include the immunoglobulins (IG) or antibodies, the T cell receptors (TR), the major histocomp...
|
PMID: 18424816
PDF is available here.
PDF is available here.
Hepatology (48)1 2008
Abstract
We asked whether HLA class II genotypes associated with HCV clearance are shared between Caucasian and African Americans and whether they contribute to enhanced antiviral CD4 T cell response. In a cohort of 93 HCV-seropositive subjects from Northeast America with defined ethnicity, virological outco...
|
PMID: 18537178
PDF is available here.
PDF is available here.
Transplantation (85)12 2008
Abstract
Logistic regression analysis revealed a strong correlation between the number of triplet or extended-triplet and eplet mismatches and both the presence and magnitude of alloantibody to mismatched HLA-A and -B specificities. The additional structural information provided by eplet analysis gave increa...
|
PMID: 18580476
PDF is available here.
PDF is available here.
Abstract
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown etiology but lymphocytic portal tract infiltration is suggestive of an immune-mediated basis for this disease. Associations with inflammatory bowel disease (IBD) especially ulcerative colitis (UC), and with partic...
|
PMID: 18528932
PDF is available here.
PDF is available here.
Abstract
We have studied genetic variations in the MHC, cytokines and CCR2-CCR5 loci in the Asian-Indian HIV-infected population and compared with other global populations....
|
PMID: 18321617
PDF is available here.
PDF is available here.
Journal of Virology (82)11 2008
Abstract
We show that in vivo EP augmented cellular and humoral immune responses to a human immunodeficiency virus type 1 Env DNA vaccine in mice and allowed a 10-fold reduction in vaccine dose. This enhancement was durable for over 6 months, and re-exposure to antigen resulted in anamnestic effector and cen...
|
PMID: 18353952
PDF is available here.
PDF is available here.
Abstract
Non-infectious uveitis is characterised by a breakdown of immunological tolerance. Several cytokines could be identified as important regulators of the immune system during induction, progression and remission of ocular inflammation in animal models. This review analyses the current knowledge on cyt...
|
PMID: 18516777
PDF is available here.
PDF is available here.
Journal of Virology (82)11 2008
Abstract
We immunized mice with insect cell-derived human papillomavirus type 16 VLPs and capsomeres. VLPs induced consistently higher antibody titers than capsomeres but the two forms induced similar CD8 T-cell responses after subcutaneous, intranasal, and oral immunization, and at least 20 to 40 times more...
|
PMID: 18385253
PDF is available here.
PDF is available here.
Autoimmunity Reviews (7)5 2008
Abstract
We highlight the current findings in the genetics of human SLE after using these approaches....
|
PMID: 18486920
PDF is available here.
PDF is available here.
Genetic Epidemiology (32)4 2008
Abstract
We provide a detailed technical description of the use of grammatical evolution to optimize neural networks (GENN) for use in genetic association studies. We compare the performance of GENN to that of a previous machine-learning NN application--genetic programming neural networks in both simulated a...
|
PMID: 18265411
PDF is available here.
PDF is available here.
Tissue Antigens (71)4 2008
Abstract
Abstract
We review studies of the immunogenetic features of IgE in allergic diseases, highlighting the major advances and the experimental limitations....
|
PMID: 18261159
PDF is available here.
PDF is available here.
Abstract
IMGT, the international ImMunoGeneTics information system (http://imgt.cines.fr), is the reference in immunogenetics and immunoinformatics. IMGT standardizes and manages the complex immunogenetic data which include the immunoglobulins (IG) or antibodies, the T cell receptors (TR), the major histocom...
|
PMID: 17949886
PDF is available here.
PDF is available here.
Abstract
We summarize the findings of recent investigations on macrophages,dendritic cells and gammadelta T lymphocytes in the response to mycobacteria....
|
PMID: 18376078
PDF is available here.
PDF is available here.
Abstract
According to the prespecified per-protocol analysis, the percentages (95% CIs) of MenACWY 2-, 3-, and 4-month recipients with hSBA titers >or=1:4 after primary immunization were serogroup A, 93% (84%-98%); C, 96% (89%-99%); W-135, 97% (90%-100%); and Y, 94% (86%-98%). With a post hoc intention-to-tr...
|
PMID: 18182599
PDF is available here.
PDF is available here.
Abstract
Therapeutic proteins in general induce an immune response, especially when administered as multiple doses over prolonged periods. Non-human therapeutic proteins such as asparaginase and streptokinase induce antibodies by the classical immune reaction and their primary immunogenic factor is the degre...
|
PMID: 18606364
PDF is available here.
PDF is available here.
BMC Bioinformatics (9)1 2008
Abstract
A probabilistic approach based on an analysis of the standardized tool "output" is proposed to infer the probability distribution of the "true trimmming process" and to provide plausible biological hypotheses explaining this process. We collated a benchmark dataset of TR alpha (TRA) and TR gamma (TR...
|
PMID: 18831754
PDF is available here.
PDF is available here.
Abstract
We have correlated the clinical outcome with the level of HLA matching in 423 patients who received a transplant from a volunteer unrelated donor in the United Kingdom. HLA matching was performed at the allelic level (i.e. high-resolution) using reference strand mediated conformation analysis (RSCA)...
|
PMID: 17964196
PDF is available here.
PDF is available here.
Abstract
New original data are presented on the use of achievements in human molecular immunogenetics in the management of type 1 diabetes mellitus. They include materials allowing for the prediction of the development of the disease at the population, family, and individual levels along with novel approache...
|
PMID: 19140398
PDF is available here.
PDF is available here.
Human Immunology (69 Suppl 1) 2008
Abstract
Anticancer Research (28)5A 2008
Abstract
In the control group, the tumor gradually grew to be 20.7+/-1.6 (mean+/-SD) mm in intratumorally injected tumors and 21.8+/-3.7 mm in opposite tumors seven weeks after injection, respectively. In contrast, in the treatment group, the tumor was reduced to 3.6+/-8.2 mm and 3.7+/-8.2 mm. The tumor grow...
|
PMID: 19035311
PDF is available here.
PDF is available here.
Abstract
We will overview the linkage and candidate gene studies carried out so far as well as summarize important historical notes on the genetic hypotheses generated in preeclampsia research. Moreover, the influence of maternal and fetal genes and their interaction as well as the role of genomic imprinting...
|
PMID: 18184097
PDF is available here.
PDF is available here.
Abstract
We review the IMGT Scientific chart rules for the description of the IgSF (V and C types) and of the MhcSF (G type) domains. These rules are based on the IMGT-ONTOLOGY axioms and concepts and are applicable for the sequence and structure analysis, whatever the species, the IgSF or MhcSF protein, or...
|
PMID: 18208865
PDF is available here.
PDF is available here.
Abstract
We examine the role of HLA genes, cytokine genes, and cell surface receptor genes as examples of how genetic polymorphism leads to individual and population variations in immune responses to vaccines. In turn, this data, in concert with new high-throughput technology, inform the immune-response netw...
|
PMID: 17971814
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We investigated the immunogenicity of Bcr-Abl-regulated antigens by stimulating CD8(+) T lymphocytes with autologous dendritic cells transfected with RNA coding for Bcr-Abl wild-type or a kinase-deficient mutant. Significant HLA class I-restricted T-cell responses were detected against antigens regu...
|
PMID: 17579186
PDF is available here.
PDF is available here.
Abstract
We have studied 264 unselected T-ALLs (171 adults and 93 children) and show that T-ALLs expressing high levels of TLX1 (n = 35, 13%), defined as a real-time quantitative polymerase chain reaction (RQ-PCR) level of TLX1 greater than 1.00 ABL, form a homogeneous oncogenic group, based on their uniform...
|
PMID: 17609427
PDF is available here.
PDF is available here.
Abstract
Abstract
We evaluated the influence of the nonreducing terminal monosaccharide on the serum antibody response. To this end, we prepared synthetic oligosaccharides comprising hexa- to tridecasaccharide fragments of the native O-SP, having one of the four monosaccharide residues that constitute the repeating u...
|
PMID: 17726093
PDF is available here.
PDF is available here.
Abstract
The discovery of innate immune genes, such as those encoding Toll-like receptors (TLRs), nucleotide-binding oligomerisation domain-like receptors (NLRs), and related signal-transducing molecules, has led to a substantial improvement of our understanding of innate immunity. Recent immunogenetic studi...
|
PMID: 17646026
PDF is available here.
PDF is available here.
Abstract
Vitiligo is a common dermatological disorder characterized by the presence on the skin of depigmented macules resulting from the destruction of cutaneous melanocytes. Autoimmunity is an important hypothesis with regard to vitiligo aetiology and the evidence for autoimmune responses being involved in...
|
PMID: 17658994
PDF is available here.
PDF is available here.
Human Immunology (68)8 2007
Abstract
We have evaluated a 14-bp deletion polymorphism in the 3'-untranslated region of exon 8 of HLA-G gene in pregnant PE women and controls. HLA-G genotypes in both control and PE women were in Hardy-Weinberg equilibrium. The healthy pregnant and PE women had similar genotype frequencies (p = 0.789). Th...
|
PMID: 17678721
PDF is available here.
PDF is available here.
Human Immunology (68)7 2007
Abstract
The distribution of HLA class II alleles and genotypes in Israelis of different ethnic origin with adult-onset type 1 diabetes (T1D) was examined. The results were compared with published findings in healthy Israelis and childhood-onset T1D Israelis. An additional comparison was made between subgrou...
|
PMID: 17584585
PDF is available here.
PDF is available here.
Abstract
Non-HLA genetics involving the study of single-nucleotide polymorphisms (SNPs) and microsatellites of cytokine and cytokine receptor genes, and as well as genes associated with response to infection and therapeutic drugs, are currently being studied for associations with diseases, including autoimmu...
|
PMID: 17448956
PDF is available here.
PDF is available here.
Plant Journal (50)5 2007
Abstract
We have developed an approach that involves labelling chloroplasts from individual cell types by placing the foreign yellow fluorescent protein (YFP) on their outer surface, and then isolating those labelled chloroplasts immunogenically. Cell specificity is achieved through the use of enhancer trap...
|
PMID: 17461787
PDF is available here.
PDF is available here.
Acta Diabetologica (44)2 2007
Abstract
We examined the clinical characteristics and the patterns of anti-GAD antibody (GADA), IA-2 antibody (IA-2A), HLA-DR and HLA-DQ in Korean adult-onset T1DM patients. Adult-onset patients had higher serum C-peptide levels than child-onset patients. In adult-onset patients, the prevalence of GADA and I...
|
PMID: 17530466
PDF is available here.
PDF is available here.
Tissue Antigens (69)5 2007
Abstract
Molecular Immunology (44)12 2007
Abstract
These results contribute to a better understanding of the mechanisms involved in the significant high immunogenicity of particulate antigen and may provide knowledge for the rational design and development of future vaccines....
|
PMID: 17408743
PDF is available here.
PDF is available here.
Gastroenterology (132)5 2007
Abstract
Natalizumab induced response and remission at Week 8 that was sustained through Week 12. Response and remission rates for natalizumab were superior to those for placebo at Weeks 4, 8, and 12, demonstrating the early and sustained efficacy of natalizumab as induction therapy in patients with elevated...
|
PMID: 17484865
PDF is available here.
PDF is available here.
Tissue Antigens (69) 2007
Abstract
The aim of the study was to investigate whether human leukocyte antigen (HLA) allele sharing between partners or the maternal killer immunoglobulin-like receptor (KIR) repertoire is associated with recurrent spontaneous abortion (RSA) and repeated implantation failure after in vitro fertilization (I...
|
PMID: 17445221
PDF is available here.
PDF is available here.