Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Radiation Genetics (0):
Recent article
Radiation Genetics
Genetika (Moskva) (46)3 2010
Abstract
The results of radiation genetics studies are reviewed. The first series of studies concerned the role of heterogeneity of the human population for radiosensitivity of chromosomes in determining the pattern of dose-response relationships; correctness of extrapolation of averaged experimental data to...
|
PMID: 20391773
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
During the last decade, a number of studies have supported the hypothesis that there is an important genetic component to the observed interpatient variability in normal tissue toxicity after radiotherapy. This review summarizes the candidate gene association studies published so far on the risk of...
|
PMID: 18314067
PDF is available here.
PDF is available here.
Mutation Research (658)1-2 2008
Abstract
Efforts at protecting people against the harmful effects of radiation had their beginnings in the early 1900s with the intent of protecting individuals in medicine and associated professions. Such efforts remain vital for all of us more than 100 years later as part of our 'learning to live with ioni...
|
PMID: 18096428
PDF is available here.
PDF is available here.
Abstract
In vivo exposure effects of electromagnetic fields (EMFs) on various tissues of experiment animals have been investigated. In this sense, modeling and formulation of these biological effects have been of significant importance. In this study extremely low frequency (ELF) EMFs effects on malondialdeh...
|
PMID: 17240475
PDF is available here.
PDF is available here.
Journal of Cardiovascular Pharmacology (47)Supplement 2 2006
Abstract
Clinical Oncology (18)3 2006
Abstract
Advances in molecular and cellular biology are transforming our understanding of breast cancer and promise the same for radiotherapy over the next few years. At the clinical level, the molecular basis of fractionation dependency and other tumour and normal tissue responses are likely to become clear...
|
PMID: 16605047
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Radiation-genetic effects are characterized by large quantitative difference. After the low dose radiation appearance of mutation is the largest in Drosophila, substantially lower in mice, especially if irradiation was protracted, and practically absent in humans. As the possible grounds of this dif...
|
PMID: 17133728
PDF is available here.
PDF is available here.
Radiation Research (163)3 2005
Abstract
We have tried to address these questions using the hypoxanthine phosphoribosyl transferase (HPRT) mutation assay in V79 Chinese hamster cells irradiated with ultraviolet A or B radiation. Delayed HPRT(-) mutations, which are indications of genomic instability, were detected by incubating the cells i...
|
PMID: 15733036
PDF is available here.
PDF is available here.
Acta Oncologica (44)8 2005
Abstract
We are still far from having an exhaustive understanding of the genetics that may underlie differences in clinical normal tissue radiosensitivity. Recent technical advances and emerging insights to the structure of inter-individual genetic variation open up unprecedented opportunities to dissect the...
|
PMID: 16332587
PDF is available here.
PDF is available here.
Abstract
Radiation Research (161)3 2004
Abstract
Our results provide a global and integrated view of the alteration of gene expression associated with radiation enteritis. They suggest that radiation enteritis is a dynamic process involving constant remodeling of each structural component of the intestinal tissue, i.e. the mucosa, the mesenchyme,...
|
PMID: 14982484
PDF is available here.
PDF is available here.
Mutation Research (543)2 2003
Abstract
The doubling dose (DD) is a very valuable concept in attempts to assess the genetic risks of radiation in man. It was long thought that the value of the doubling dose obtained from specific locus experiments in mice could be applied to man. James Neel, as a result of his studies on the offspring of...
|
PMID: 12644180
PDF is available here.
PDF is available here.
Mutation Research (543)2 2003
Abstract
We devised an electrophoretic-specific locus test so that biochemical mutations leading to alterations in the activity or amount of four enzymes and proteins, as well as charge changes could be detected. We measured the yield of recessive visible and electrophoretic mutations in the same experiment...
|
PMID: 12644183
PDF is available here.
PDF is available here.
Abstract
This is the result of studying on a problem of radio-induced ageing. From the point of view of radiation genetics it is perspective to investigate influence of low doze irradiation on individuals with the mutant phenotypes that allows to assume a role of separate genes and mechanisms controllable by...
|
PMID: 12754819
PDF is available here.
PDF is available here.
Abstract
We have shown that natural drosophila populations from the settlement Vetka of Gomel region with increased radiation background are more adapted to mutagenic effect of radiation than drosophila populations from Berezinsky reserve (the control). After the populations were placed into laboratory therm...
|
PMID: 12754812
PDF is available here.
PDF is available here.
Abstract
A concept of polygenomic realization of mutagenic effects in the human body exposed to low-dose radiation on the basis of cell reproductions of genomic damages (Nig = 2n/2) was suggested. The above-said is in agreement with the principles of non-threshold mutagenic action of radiation and biological...
|
PMID: 12754797
PDF is available here.
PDF is available here.
Abstract
Mutation Research (512)2-3 2002
Abstract
We have been greatly under-estimating the damage produced in chromatin by such agents as ionising radiation. This article gives a brief historical summary of observations leading up to this conclusion, and after outlining some of the problems surrounding the formation of complex chromosomes exchange...
|
PMID: 12464345
PDF is available here.
PDF is available here.
Abstract
Radiation Research (158)3 2002
Abstract
Around 30 years ago, a very prominent molecular biologist confidently proclaimed that nothing of fundamental importance has ever been learned by irradiating cells! The poor man obviously did not know about discoveries such as DNA repair, mutagenesis, connections between mutagenesis and carcinogenesi...
|
PMID: 12175305
PDF is available here.
PDF is available here.
Abstract
Cancer patients exhibit large patient-to-patient variability in normal tissue reactions after radiotherapy. Several observations support the hypothesis that clinical normal tissue radiosensitivity is influenced by genetic factors. However, very little is known about the genetic variation possibly un...
|
PMID: 12242122
PDF is available here.
PDF is available here.
Abstract
Genetika (Moskva) (38)3 2002
Abstract
A cytogenetic study was conducted for the first time on human populations neighboring the Semipalatinsk nuclear test site (STS) and exposed to ionizing radiation for a long period of time. In populations with the extreme and maximum radiation risks, high frequencies of radiation-induced chromosomal...
|
PMID: 11963566
PDF is available here.
PDF is available here.
Abstract
Abstract
Over the period from 1998 to 2000 adaptation to unfavorable ecological factors was revealed to be formed in natural Drosophila melanogaster populations from various regions of Belarus with increased radiation background due to the Chernobyl accident. This adaptation was shown to be of non-specific c...
|
PMID: 12004604
PDF is available here.
PDF is available here.
Abstract
The comparative study of effects of low doses of radiation on peripheral blood lymphocytes of persons occupationally exposed to radiation and non-exposed ones was carried out. The main attention was paid to radio-adaptive response forming under consistent exposure to low (0.05 Gy) and damaging (2 Gy...
|
PMID: 12530136
PDF is available here.
PDF is available here.
[Mutation at the T-cell receptor locus in people a long time after acute and prolonged irradiation].
Abstract
The frequency of lymphocytes with mutations at genes of T-cell receptor (TCR) is determined in 165 persons exposed to ionizing radiation 16-40 years after the influence. Depending on a type of irradiation and time, elapsed from the moment of exposure, all inspected persons were divided into 3 groups...
|
PMID: 12530138
PDF is available here.
PDF is available here.
Abstract
Children and adults affected by the Chernobyl accident suffer with lipoperoxic stress coupled with hypovitaminoses A and E, the syndrome and its radiogenic mechanisms described by the authors previously. The relation of these biochemical disturbances to somatic consequences on mutagenic and teratoge...
|
PMID: 12530137
PDF is available here.
PDF is available here.
Abstract
In work, on the basis of known base biological laws, the new natural three-dimensional designs are under construction: codonogram and aminogram. Codonogram and aminogram have revealed the new laws of coding and constructions in molecular biology. The secondary coding codonogram, at the expense of re...
|
PMID: 12530139
PDF is available here.
PDF is available here.
Abstract
Chromosomal aberrations in somatic cells (circulating lymphocytes) have been investigated in a remote period in different groups of people who suffered from radiation accidents. The chromosomal radiation markers were found even decades after irradiation. The question about the necessity of registrat...
|
PMID: 12530150
PDF is available here.
PDF is available here.
Abstract
Genetic Epidemiology (21)2 2001
Abstract
The International Genetic Epidemiology Society (IGES) has examined the charges against James V. Neel and his colleagues contained in the recently published book by Patrick Tierney entitled Darkness in El Dorado: How Scientists and Journalists Devastated the Amazon (W.W. Norton, 2000). The book impli...
|
PMID: 11507719
PDF is available here.
PDF is available here.
Abstract
These results indicate that low doses of radiation can induce multiple changes in human germline DNA....
|
PMID: 11375082
PDF is available here.
PDF is available here.
Abstract
Here, a new theory of molecular phylogeny is developed in a multidimensional vector space (MVS). The molecular evolution is represented as a successive splitting of branch vectors in the MVS. The end points of these vectors are the extant species and indicate the specific directions reflected by the...
|
PMID: 11319265
PDF is available here.
PDF is available here.
Health Physics (80)4 2001
Abstract
This paper provides a brief overview of the advances in the field of the estimation of the genetic risks of exposure of human populations to ionizing radiation from the early 1950's to the present and of the developments that are anticipated in the coming years. The latter are based on the view that...
|
PMID: 11281204
PDF is available here.
PDF is available here.
Shi yan sheng wu xue bao (34)1 2001
Abstract
The Gossypium hirsutum cv. Liaomian No. 9 were mutagenized by 60Co gamma ray, from which the mutant line Zhonghuzhi PI 935 (be called "PI 935" for short) was bred by family selection method. The PI 935 not only has some good traits (growing period, drought tolerance, lint color and fiber quality) si...
|
PMID: 12549010
PDF is available here.
PDF is available here.
Abstract
Frequencies of chromosomal translocations in human peripheral blood lymphocytes irradiated in vitro by 200 kV X rays have been estimated by the fluorescence in situ hybridisation (FISH) technique. Probes specific for whole chromosomes 1, 3 and 4 were labelled with, biotin 16 dUTP + digoxigenin 11 dU...
|
PMID: 11468799
PDF is available here.
PDF is available here.
Abstract
During all the history of the development of radiation biology a problem of "energy paradox"--low consumption of energy of ionizing and non-ionizing radiation in realization of irradiation effect--has been in the focus. The first principle, which contributed much to quantitative concepts of radiatio...
|
PMID: 11721348
PDF is available here.
PDF is available here.
Abstract
Based on the reports of UNSCEAR for the period from 1958 to 2001 the paper presents a retrospective analysis of the use of direct methods and the doubling dose method for quantitative determination of the genetic risk of human exposure expressed as different hereditary diseases. As early as 1962 UNS...
|
PMID: 11721355
PDF is available here.
PDF is available here.
Abstract
According to the analysis of epidemiological and experimental data there are evidences in threshold on criterion of mutagenic (in broad sense) ionising radiation action. A threshold takes place in the region of about 20-200 mGy concerning a dose in case of an acute exposure and in the region of the...
|
PMID: 11721351
PDF is available here.
PDF is available here.
Abstract
The Joint Institute for Nuclear Research has the unique sources of ionizing radiation. The different radiobiological researches have been carried out at the JINR accelerators for more than forty years. They are connected not only to the solution of fundamental problems of radiation genetics but also...
|
PMID: 11721347
PDF is available here.
PDF is available here.
Abstract
It was demonstrated that preliminary irradiation of wheat seeds with doses of 0.10 and 0.25 Gy reduced the sensitivity to the clastogenic action of the challenge doses of gamma-irradiation at 10 and 20 Gy, but not to a doses at 50 and 100 Gy. The adaptive response (AR) was observed. It was found tha...
|
PMID: 11721352
PDF is available here.
PDF is available here.
Abstract
DEPENDENCE OF FREQUENCY OF X-RAY-INDUCED CHROMOSOME ABERRATIONS ON DOSE RATE IN THE CHINESE HAMSTER.
Abstract
Mammalian Genome (11)7 2000
Abstract
We have summarized our extensive series of mutagenesis experiments to isolate dominant mutations in the mouse that express eye morphological defects. Thirty-two experimental groups in which parental mice were exposed to chemical mutagens or irradiation and a historical control group of the laborator...
|
PMID: 10886015
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Animal Biotechnology (10)3 1999
Abstract
We have used a rapid approach to place markers that are already represented in current genetic maps onto individual chromosomes in species for which chromosome paints exist. PCR-based techniques are used to look for the presence of individual marker genes within each chromosome-specific DNA pool. Th...
|
PMID: 10721432
PDF is available here.
PDF is available here.
Annals of the ICRP (29)3-4 1999
Abstract
This report reviews data on naturally-occurring multifactorial diseases and develops a mathematical model to predict the impact of radiation-induced mutations on the frequencies of these diseases in the population. It provides an outline of the aetiological features and examples of multifactorial di...
|
PMID: 11108911
PDF is available here.
PDF is available here.
Abstract
Mammalian Genome (9)6 1998
Abstract
Abstract
Mutation Research (413)1 1998
Abstract
We wish to propose some solutions using both methodological and statistical approaches. Firstly, we have tried to check the micronuclei assay in order to obtain a sufficient number of micronuclei in binucleated cells in the shortest time possible, even at higher exposition dose. Two techniques were...
|
PMID: 9602858
PDF is available here.
PDF is available here.
Abstract
Health Physics (71)5 1996
Abstract
Abstract
The paper summarises some methodological approaches which may be used in experimental modelling and study of hereditary radiation effects in mammals. These approaches are aimed to the elucidation of the possible specific character (aggravation) of radiation damage in the offspring determined by the...
|
PMID: 9026299
PDF is available here.
PDF is available here.
Abstract
I S H). It summarizes the application of this technology in fundamental and applied fields of radiation cytogenetics and emphasizes the important role of FISH for biological dosimetry of human exposure to ionizing radiation....
|
PMID: 9005640
PDF is available here.
PDF is available here.