Abstract
This paper examines the exchange relationships between women undergoing abortion, the clinicians who procure fetal tissue and stem cell scientists in Britain, and argues that the fetal tissue economy is an important dimension of the gendered bioeconomy that underpins stem cell science. In so doing i...
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PMID: 18945530
PDF is available here.
Abstract
We identified three proteins with different expression after Cd-treatment; dihydropyrimidinase-related protein 2 (DRP-2/CRMP-2), 14-3-3-epsillon and calmodulin (CaM). Though the number of identified proteins was small, these proteins are known to be involved in neuronal development. The present stud...
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PMID: 18835323
PDF is available here.
Abstract
We have called the duty of care which women feel towards babies and children. The duty of care might apply to other research using aborted fetuses. But what makes stem cell research more troubling is its association with renewal, regeneration, and immortality which participants understood as somehow...
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PMID: 18375029
PDF is available here.
S Ponnusamy,
N Mohammed,
S S Y Ho,
H M Zhang,
Y H Chan,
Y W Ng,
L L Su,
A P Mahyuddin,
A Venkat,
J Chan,
M Rauff,
A Biswas and
M Choolani
Abstract
We recovered 37% of spiked FNRBCs (95% confidence interval (CI) 28.5-45.6; n = 8) in in vitro experiments. We show a consistent threefold increase in the number of epsilon + FNRBCs in maternal blood obtained immediately post-TOP (p = 0.005). A mathematical relationship was derived: observed number o...
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PMID: 18509867
PDF is available here.
Abstract
We demonstrate that delivery of FPC is feasible with intratracheal injection giving the most reliable, diffuse delivery throughout the lung. This represents the first step toward translational research with site-specific delivery for a cell-based therapeutic approach toward PH and similar pulmonary...
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PMID: 17686493
PDF is available here.
Abstract
Stem cells are the self-renewing progenitors of several body tissues and are classified according to their origin and their ability to differentiate. Current research focuses on the potential uses of stem cells in medicine and how they can provide effective treatment for a range of d...
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PMID: 18454634
PDF is available here.
Abstract
Stem cells are the self-renewing progenitors of several body tissues and are classified according to their origin and their ability to differentiate. Current research focuses on the potential uses of stem cells in medicine and how they can provide effective treatment for a range of d...
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PMID: 18454634
PDF is available here.
Abstract
These results suggest that clonal lines with larger sized cell populations in mean and lower PD per day have a greater in vitro developmental potential following NT....
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PMID: 19007550
PDF is available here.
Abstract
We studied the osteoblastic ultrastructural changes induced by UN in vivo and analyzed cell proliferation, generation of reactive oxygen species (ROS), apoptosis, and alkaline phosphatase (APh) activity in osteoblasts exposed to various UN concentrations (0.1, 1, 10, and 100 microM) in vitro. Cell p...
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PMID: 17106697
PDF is available here.
Abstract
Different cell sources for bone tissue engineering are reviewed. In particular, adult cell source strategies have been based on the implantation of unfractionated fresh bone marrow; purified, culture expanded mesenchymal stem cells, differentiated osteoblasts, or cells that have been modified geneti...
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PMID: 17043947
PDF is available here.
Abstract
We review these applications. We also discuss when and how to study human embryo and early fetuses and some of the regulations of this research....
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PMID: 16879189
PDF is available here.
Abstract
Recent advances in genomics and biotechnology have ushered in a new era in health development. Therapeutic cloning possesses enormous potential for revolutionizing medical and therapeutic techniques. Cloning technology, however, is perceived as having the potential for reproductive cloning, which ra...
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PMID: 17361676
PDF is available here.
Abstract
Modern advances in human genetic and reproductive technologies are among the recent developments disturbing the balance between the spiritual and the material components of life. This paper gives an Islamic perspective on some of these advances, including abortion, in vitro fertilization, genetic en...
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PMID: 17361675
PDF is available here.
Abstract
We condone the harvesting, and indeed the taking of the donor's life. Irrespective of the medical benefits for which we may be hoping, we cannot relieve the suffering of one human individual by exploiting another....
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PMID: 15846535
PDF is available here.
Abstract
The role of the stem cell (SC) in physiology and physiopathology has recently attracted much interest. SCs may originate from embryos, aborted fetuses, umbilical cord blood, and adult organs and tissues. In the adult, SCs were first defined in tissues with a high cell turnover, like skin and gut. To...
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PMID: 15467516
PDF is available here.
Abstract
The role of the stem cell (SC) in physiology and physiopathology has recently attracted much interest. SCs may originate from embryos, aborted fetuses, umbilical cord blood, and adult organs and tissues. In the adult, SCs were first defined in tissues with a high cell turnover, like...
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PMID: 15467516
PDF is available here.
Abstract
The role of the stem cell (SC) in physiology and physiopathology has recently attracted much interest. SCs may originate from embryos, aborted fetuses, umbilical cord blood, and adult organs and tissues. In the adult, SCs were first defined in tissues with a high cell turnover, like...
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PMID: 15467516
PDF is available here.
Abstract
The role of the stem cell (SC) in physiology and physiopathology has recently attracted much interest. SCs may originate from embryos, aborted fetuses, umbilical cord blood, and adult organs and tissues. In the adult, SCs were first defined in tissues with a high cell turnover, like...
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PMID: 15467516
PDF is available here.
Abstract
The role of the stem cell (SC) in physiology and physiopathology has recently attracted much interest. SCs may originate from embryos, aborted fetuses, umbilical cord blood, and adult organs and tissues. In the adult, SCs were first defined in tissues with a high cell turnover, like...
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PMID: 15467516
PDF is available here.
Abstract
The role of the stem cell (SC) in physiology and physiopathology has recently attracted much interest. SCs may originate from embryos, aborted fetuses, umbilical cord blood, and adult organs and tissues. In the adult, SCs were first defined in tissues with a high cell turnover, like...
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PMID: 15467516
PDF is available here.
Abstract
The presence and persistence of fetal cells in murine maternal tissue was first reported over 20 years ago, although it is only more recently that the occurrence and potential consequences of fetomaternal cell trafficking in humans have been fully appreciated. Fetal cell microchimerism is a growing...
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PMID: 15319378
PDF is available here.
Abstract
Our understanding of the pathogenesis of human diseases such as diabetes, multiple sclerosis, retinopathy of prematurity and osteoporosis has been advanced because of such experiments, and better drug treatment of disorders such as osteoarthritis has been made possible with the use of human fetal ti...
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PMID: 14609421
PDF is available here.
Abstract
The Dutch Law on Foetal Tissue (Wet Foetaal Weefsel) sets out conditions and regulations concerning the donation, storage and permissibility of use of foetal tissue. Each institution where foetal tissue becomes available has to formulate an in-house code of conduct describing how the law will be app...
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PMID: 12892010
PDF is available here.
Abstract
Under the auspices of the Kwaliteitsinstituut voor de Gezondheidszorg CBO [Dutch Institute for Healthcare Improvement] a standard code of practice was developed as a template for local institutional codes to implement the Law on Foetal Tissue. It is a useful model code, but arguments should have bee...
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PMID: 12892007
PDF is available here.
Abstract
Ethics is an essential dimension of the clinical management of pregnancies complicated by fetal anomalies. Utilizing the ethical principles of beneficence and respect for autonomy, this review first sets out the ethical concept of the fetus as a patient. This concept provides the basis for a compreh...
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PMID: 12832939
PDF is available here.
Abstract
We conducted a gross anatomic study of 90 adult and four fetal hemipelves. Using various non-surgical approaches, the anatomic relations and pathways of the IHP were dissected. The IHP extended from the sacrum to the genital organs at the level of the lower sacral vertebrae. It originated from three...
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PMID: 12589666
PDF is available here.
Abstract
The Japanese Pharmaceutical Law was revised at the end of July 2002. The important features of this revision are the postmarketing safety scheme, especially for biological products, and reconstruction of the legislation for effective pharmaceutical development. This is based on the national policy t...
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PMID: 12693010
PDF is available here.
Abstract
We become involved in the juncture between science and religion, which needs to be carefully explored....
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PMID: 12696784
PDF is available here.
Abstract
It may be that the current system of formal definitions, ethical theories, and voluntary professional guidelines to protect patients from unwittingly becoming subjects of research is inadequate to meet the challenge of surgical innovation. Important questions, such as when surgical innovation become...
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PMID: 12696792
PDF is available here.
Abstract
The research on different aspects of perinatal medicine offers valuable avenues into developmental biology and medicine that could markedly improve therapy of the pregnant patient and premature and newborn babies. Research with all sources of human cell stems should be supported to provide new thera...
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PMID: 12696785
PDF is available here.
Abstract
Both fetal and keloid fibroblasts produce significantly more TGF-beta1 than normal adult fibroblasts. Our data and the data of others suggest that fetal fibroblasts produce more bFGF than adult fibroblasts. The serum-free model we describe can be used to quantitatively measure autocrine growth facto...
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PMID: 12533134
PDF is available here.
Abstract
I call for greater clarity and honesty as these issues continue to be debated. An uncritical adherence to pluralism will encourage strategic obfuscation, but citizens of democracies need to be clearly informed about all the premises of opposing positions. Decisions about ethically and legally accept...
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PMID: 15115018
PDF is available here.
Abstract
At the forefront of modern debate over the ethical use of biotechnology is embryonic stem cell research. In this poignant analysis of its legitimacy, the author examines the history of this research in light of the United States' policy favoring the protection of human beings over scientific progres...
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PMID: 15568234
PDF is available here.
Abstract
The topic of assisted reproductive medicine (ART) illustrates the two-sidedness of all medical advances. It encompasses not only a responsibility for research, but also a responsibility to research. Current discussion revolves around the central question whether an all too strict interpretation of t...
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PMID: 12499749
PDF is available here.
Abstract
The stem cell data presented and discussed during the symposium raise the hope that important medical progress can be made in several fields: neuro-degenerative diseases, those linked to cellular deficit, some aspects of aging linked to cellular degeneration, and the treatment of can...
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PMID: 12494506
PDF is available here.