Abstract
The authors present outcomes obtained in patients who underwent Gamma Knife surgery (GKS) at 1 institution as part of a multimodal treatment of refractory epilepsy caused by hypothalamic hamartomas (HHs).
Between 2003 and 2010, 19 patients with HH underwent GKS. Eight patients had follow-up for less...
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PMID: 21121803
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Abstract
We describe the first case of a carcinoid composed of ghrelin-producing cells arising in a tailgut cyst. Ghrelin production was demonstrated using immunohistochemistry, electron microscopy, and reverse transcription-polymerase chain reaction methods. A 73-year-old woman with back and pelvic pain was...
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PMID: 20532674
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Abstract
Five southern red-backed voles (Myodes gapperi) of the first generation of a wild-caught breeding colony were presented with lesions at the maxillary incisors consistent with elodontoma. The affected animals had a history of chronic weight loss, were >16 months of age, and were siblings. Radiographs...
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PMID: 20945662
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Abstract
Palatal clefts in conjunction with space-occupying lesions of the oral or nasal cavities are of interest because they may represent a developmental etiology of palatal clefts. Epignathus is a rare space-occupying tumor of the nasopharynx that can arise from the upper jaw, palate, and sphenoid. It ca...
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PMID: 20856072
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Abstract
Our case is the first reported case of lipofibromatous hamartoma of the median nerve in the pediatric age group....
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PMID: 20606583
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Abstract
An asymptomatic 17-month-old male infant was incidentally found to have a hepatic mass measuring 12cm in maximum dimension. The histopathologic appearance of the resected mass was that of a typical mesenchymal hamartoma. Spindle cells that comprised a predominant cellular constituent of the lesion w...
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PMID: 20399572
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Abstract
We wanted to assess the frequency of this finding and to consider its possible significance. Twenty-five consecutive cases of ovarian MCT (patient age ranging from 23 to 66 years, mean: 36.3 years; size ranging from 2.5 to 11.5 cm, mean: 6.1 cm) diagnosed in 2008 were retrieved from the archives at...
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PMID: 20534997
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Abstract
We report a case of a 17-year-old man with a large NCH resected from the posterior scalp showing involvement of the bone marrow....
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PMID: 20414093
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Abstract
Becker nevus syndrome is a phenotype characterized by the fundamental presence of Becker's nevus with ipsilateral hypoplasia of the breast or other skin, skeletal and/or muscular disorders. This syndrome generally originates at birth, intensifies significantly in adolescence and is one of the syndro...
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PMID: 20676475
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Abstract
We present the case of a 7 days-old girl with a retrorectal tumor diagnosed by ultrasound during pregnancy. The histological examination was a cyst lined by squamous and urotelial typical epithelium and a double layer of smooth muscle. The treatment of choice is the complete excision of the lesion,...
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PMID: 20544128
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Abstract
We had another look at a chest X-ray that had been taken 6 years before, we had found a pulmonary nodule of 18 mm in size. The chest X-ray and computed tomography (CT) taken at admission showed a round nodule with calcification in the same site, with increasing in size to 30 mm. The tumor could not...
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PMID: 20446614
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Abstract
We present the case of a parotid gland hamartoma with oncocytic and sebaceous metaplasia arising as a 3-cm mass in a 70-year-old man. To the best of our knowledge, there has been no previous report of a tumor with the same features. We present this case to create awareness of hamartomas as part of t...
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PMID: 20461675
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Abstract
We report a rare case of giant bone island of femur concurrent with ipsilateral femoral head necrosis. Although roentgenographic features indicated the possible diagnosis of bone island, there were unusual findings, such as a huge expansion of the lesion, increased uptake of radionuclide on bone sca...
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PMID: 19306007
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Abstract
Color Doppler twinkling artifacts are additional useful sonographic signs in the diagnosis of calcified lesions, urinary and biliary stones, gallbladder adenomyomatosis, and some miscellaneous conditions....
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PMID: 20375381
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Abstract
We present an unusual outcome of long term GnRHa therapy in two girls with central precocious puberty(CPP) of idiopathic or organic origin. They have received monthly depot injections of triptorelin acetate for a time period of 8 years. Thyroid function was examined by measuring serum levels of thyr...
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PMID: 20583547
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Abstract
The histogenesis of folliculosebaceous cystic hamartoma (FSCH), including the origin of the frequently associated adipocytes and other mesenchymal components, remains unclear. There are controversial problems regarding FSCH, such as the relationship between FSCH and trichofolliculoma (TF), and the e...
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PMID: 19755908
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Abstract
Von-Meyenburg complexes (VMCs) have been shown to progress to cholangiocarcinoma (CC) in some cases. Histologic examination in such cases reveals a gradual transition of VMCs to intermediate lesions and finally to CC. The goal of this study was to determine if this histologic progression was also ac...
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PMID: 19770706
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Abstract
We present a case of a 49-year-old woman who presented with left-sided hearing loss of more than 4 years' duration and vertigo since childhood. Magnetic resonance imaging revealed a mass on the intracanalicular segment of cranial nerve VIII on the left side, consistent with acoustic schwannoma. She...
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PMID: 20229478
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Abstract
We diagnosed an esophageal hamartoma in an infant girl who had first presented when she was 8 days old with symptoms of apnea and cyanosis. The patient had undergone a multitude of tests since her birth, and she was eventually diagnosed with episodic bradycardia. When the patient was 6 weeks old, we...
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PMID: 20229470
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Neurosurgery (66)3 Suppl Operative 2010
Abstract
Total removal of the neoplasm was accomplished in 37 of 46 patients with craniopharyngiomas (80.4%), whereas subtotal resection was performed in hypothalamic gliomas. No significant differences in pre- and postoperative hormonal disturbances were observed in 37 craniopharyngiomas and 10 hypothalamic...
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PMID: 20173574
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Abstract
We report the case of a healthy, 60-year-old woman with an incidentally discovered chondromatous hamartoma that was thorascopically excised. Her pulmonary hamartoma was predominantly cartilaginous, which only occurs in 1% of hamartomas....
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PMID: 20065908
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Abstract
We report a histologically proven case of an endobronchial lipomatous hamartoma with extrabronchial-mediastinal extension in a 64-year-old patient, and we describe the computed tomography and magnetic resonance imaging findings. To our knowledge, this is the first reported case of an endobronchial h...
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PMID: 20160589
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Abstract
The 5 patients were all men, ranging in age from 6 years to 21 years (mean 12.6 +/- 6.5 years). The lesions were unilateral. Preoperative best-corrected visual acuity ranged from 20/340 to 20/50 (median 20/200), and postoperative best-corrected visual acuity ranged from 20/340 to 20/30 (median 20/10...
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PMID: 20175272
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Abstract
Hypothalamic hamartomas associated with CPP were more likely to contact the infundibulum or tuber cinereum and were larger than hamartomas not associated with CPP. GnRH, TGFalpha, and GnRHR were expressed by all hamartomas studied. Expression of KISS1, GPR54, and GRM1A did not differ significantly b...
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PMID: 20389100
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Abstract
BACKGROUND: Mesenchymal hamartoma of the chest wall is an extremely uncommon lesion of infants. Radiologic features simulate a malignant neoplasm; however, pathologic examination demonstrates an admixture of fibroblasts, benign cartilage and woven bone. There is a paucity of cytologic reports of thi...
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PMID: 20306991
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Abstract
We report a case of hypothalamic hamartoma in an adult female who presented with gelastic seizures, generalized convulsions, and ictal aggressive psychotic behavior. Anticonvulsant treatment was ineffective in controlling the epileptic seizures. Surgical excision after accurate imaging diagnosis 3 d...
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PMID: 20677592
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Abstract
We present a case of breast hamartoma in a 13-year-old boy, which interestingly, extended through but without definite involvement of the chest wall into the thoracic cavity. In view of occasional recurrence and documented malignancy in hamartomas, tumor was excised along with two ribs....
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PMID: 20479554
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Abstract
An ectopic hamartomatous thymoma is an extremely rare benign neoplasm that commonly occurs in the lower neck region. It has distinctive pathological features that include haphazardly arranged spindle cells, epithelial cells, and mature fat tissue. Its histogenesis is still controversial. This report...
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PMID: 20107954
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Abstract
This report describes a rare case of secondary carpal tunnel syndrome due to a lipofibromatous hamartoma of the median nerve. Excision of the fibrofatty tissue between the nerve fascicles without risking damage to the fascicles was impossible. The transverse carpal ligament was incised and an epineu...
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PMID: 20039769
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Abstract
We report here a case of adult-onset classical NLCS on the pinna because of its rarity and unusual location. In addition, our patient also had some rare features of NLCS, such as onset in the latter part of life, presence of foul-smelling discharge, and comedo-like plugs on the lesions....
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PMID: 20673540
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Abstract
I patient had been operated (partial resection of HH) with temporary effect which consisted of decrease in frequency of seizures for 8 months; later frequency of paroxysms increased. Main indications to radiosurgical treatment included progressive course of disease, low effectiveness of anticonvulsa...
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PMID: 20432559
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Abstract
The spectrum of hepatic tumors in children is different from that found in the older age group (adults) and also different in different populations....
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PMID: 20699496
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Abstract
We report one such case in a 20-year-old male patient. He presented with a lump in the right hypochondriac region and pain of two years duration with rapid increase in size since two months. Ultrasonography (USG) revealed a well circumscribed mass on the undersurface of the right lobe of liver sugge...
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PMID: 20551545
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Abstract
Transient central hyperthermia, hypertension, and tachycardia were observed during the coagulation procedure. Intra-hamartoma spikes and slow waves were identified on depth electrode recordings. No gelastic seizure was induced by deep stimulation. The patient was seizure-free during the 12-month fol...
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PMID: 19995691
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Abstract
A case of cutaneous rhabdomyomatous mesenchymal hamartoma in a 6-year-old Afro-Caribbean girl is reported with review of the literature. The lesions were fine, located on the central face and became inapparent after six months. Spontaneous regression of these lesions has not been previously reported...
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PMID: 20583694
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Abstract
A total of thirteen 5-minute recordings were obtained from 5 patients. Noise levels were comparable to extraoperative microwire recordings for temporal lobe epilepsy. Single-neuron spike activity was isolated from a total of 5 channels obtained during recording of 3 sessions in 3 patients. CONCLUSIO...
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PMID: 19934938
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Abstract
A 6-month-old, intact, male Weimaraner dog presented to the veterinary teaching hospital for bilateral mucopurulent ocular and nasal discharge that began at approximately 10 weeks of age. A computed tomography scan showed an expansile soft-tissue mass involving both frontal sinuses, the ethmoid regi...
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PMID: 19901304
PDF is available here.
Abstract
Two girls with central precocious puberty (CPP) associated with hypothalamic hamartoma (HH) and non classical form of congenital adrenal hyperplasia (NCAH), are reported. Case 1. The first patient, who showed at age around 4 years the onset of CPP, was submitted in view of some organic lesion to mag...
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PMID: 19794382
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Abstract
We opted to resect the tumor back to healthy median nerve fascicles and to perform graft repairs. Surgery proceeded uneventfully, without any complications. Pathology confirmed the diagnosis of lipofibrohamartoma. CONCLUSION: At 18 months postoperatively, the patient had excellent left hand function...
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PMID: 19927073
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Abstract
Our results showed 7% of these 460 girls had gonadotropin-independent precocious puberty (GIPP). The other 93% patients had GDPP and 96% of them were idiopathic. Functional ovarian cyst and hypothalamic hamartoma were leading causes of GIPP and organic GDPP, respectively. The presence of undetectabl...
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PMID: 20020583
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Abstract
We report the case of a hamartomatous lesion composed of eccrine structures and prominent angiomyxoid stroma, diagnosed in a 9-year-old girl. In this lesion, eccrine structures were not normal eccrine coils or ducts but ramified strands of small eosinophilic cells, containing a few eccrine ducts. Th...
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PMID: 19668077
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Abstract
We present two patients with macrodactyly and carpal tunnel syndrome caused by lipofibromatous hamartoma of the median nerve and discuss diagnosis and treatment of the disease. A 10-year-old girl with a congenital progressive macrodactyly of her right index finger presented with a slowly growing mas...
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PMID: 18615252
PDF is available here.