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Phyllodes Tumor (0):
Recent article
Phyllodes Tumor
Abstract
A patient with phyllodes tumour of the breast is discussed. During follow-up, she presented with intestinal obstruction caused by ileocaecal intussusception. The cause of the intussusception was metastatic phyllodes tumour, which is a unique presentation.
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PMID: 20573310
PDF is available here.
PDF is available here.
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Histopathology (57)2 2010
Abstract
To establish histological and biological parameters that can predict phyllodes tumours on core biopsy specimens of indeterminate fibroepithelial neoplasms.
Core biopsy specimens of fibroepithelial lesions diagnosed at the Department of Pathology, Singapore General Hospital from 2002 to 2007 were rev...
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PMID: 20716164
PDF is available here.
PDF is available here.
Breast Cancer (17)3 2010
Abstract
We present a case of malignant phyllodes tumor which was composed almost exclusively of a fibrosarcomatous component. A 52-year-old Japanese female noted a rapid increase of her right breast tumor. On admission, multiple lung metastases were detected by imaging. Right simple mastectomy was performed...
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PMID: 19350353
PDF is available here.
PDF is available here.
Abstract
We report an 18-year-old Kuwaiti girl who presented with a painless mass in the left labium majus, which was subsequently excised. Microscopic examination revealed morphologic pattern characteristic of benign phyllodes tumor. Immunostaining demonstrated the presence of estrogen receptors and progest...
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PMID: 20514681
PDF is available here.
PDF is available here.
Abstract
We report a case of recurrent phyllodes tumor of the vulva in a 39-year-old woman. The tumor showed biphasic morphology with a typical leaf-like pattern and a cellular stroma with rare mitosis. Expression of estrogen receptors, progesterone receptors mammoglobin, and BRST-2 was shown in the epitheli...
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PMID: 20407333
PDF is available here.
PDF is available here.
Breast Cancer (17)2 2010
Abstract
We report the case of a patient who presented with hypoglycemia associated with a giant breast mass and presence of serum high-molecular-weight insulin-like growth factor II (big IGF-II). In July 2005, a 49-year-old woman was admitted because of delirium, transient loss of consciousness, and a giant...
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PMID: 19259766
PDF is available here.
PDF is available here.
Abstract
Cancer Cytopathology (118)1 2010
Abstract
Fine-needle aspiration (FNA) sensitivity in discriminating between phyllodes tumor and its benign mimicker fibroadenoma (FA) remains low. Because a preoperative categorization of phyllodes tumor is crucial for their appropriate management, the authors undertook this study in an effor...
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PMID: 20094997
PDF is available here.
PDF is available here.
Cancer Cytopathology (118)1 2010
Abstract
Fine-needle aspiration (FNA) sensitivity in discriminating between phyllodes tumor and its benign mimicker fibroadenoma (FA) remains low. Because a preoperative categorization of phyllodes tumor is crucial for their appropriate management, the authors undertook this study in an effor...
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PMID: 20094997
PDF is available here.
PDF is available here.
Cancer Cytopathology (118)1 2010
Abstract
Fine-needle aspiration (FNA) sensitivity in discriminating between phyllodes tumor and its benign mimicker fibroadenoma (FA) remains low. Because a preoperative categorization of phyllodes tumor is crucial for their appropriate management, the authors undertook this study in an effor...
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PMID: 20094997
PDF is available here.
PDF is available here.
Histopathology (56)4 2010
Abstract
Fine Needle Aspiration Cytology (FNAC) has been replaced by Needle core biopsy (NCB) as the pathological investigation of choice in pre-operative diagnosis of breast lesions. Despite the greater yield of material with spatial information, the distinction between fibroepithelial lesions of the breast...
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PMID: 20459556
PDF is available here.
PDF is available here.
American Surgeon (76)3 2010
Abstract
We describe the first case ever reported of a malignant phylloides tumor presenting in the first trimester of pregnancy and provide insight into the complexities of management as well as a review of the known literature. An extensive PubMed literature search for "cystosarcoma," "phylloides," and "pr...
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PMID: 20349661
PDF is available here.
PDF is available here.
Abstract
We describe several hitherto unreported features including juvenile fibroadenoma-like proliferation, fibroadenoma with lactation change, and pseudoangiomatous stromal hyperplasia with multinucleated stromal giant cells in a patient with neurofibromatosis, type 1 all constituting potential diagnostic...
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PMID: 20035149
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Breast Cancer (17)1 2010
Abstract
Phyllodes tumor is an uncommon biphasic breast tumor, with the ability to recur and metastasize, and it behaves biologically like a stromal neoplasm. Traditionally, phyllodes tumors are graded by the use of a set of histologic data into benign, borderline, and malignant. In most seri...
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PMID: 19434472
PDF is available here.
PDF is available here.
Bratislavske lekarske listy (111)5 2010
Abstract
The median age at diagnosis was 45.5 years (range: 21-69 years). Seven (70%) of 10 tumors were benign and 3 (30%) were malignant. The median tumor size was 29 mm (range: 12-80 mm). The least safe margin was 1 cm. Three of 10 patients had malignant PT and underwent simple mastectomy. Local recurrence...
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PMID: 20568416
PDF is available here.
PDF is available here.
Abstract
Abstract
The purpose of our study was to review the magnetic resonance (MR) imaging findings and pathological diagnoses of benign and malignant solid circumscribed breast masses. This article reviews the MR imaging findings of solid circumscribed breast masses. A strategy for the diagnosis of solid circumscr...
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PMID: 20035410
PDF is available here.
PDF is available here.
Abstract
It is a rare neoplasm, andthe clinician must be aware of its timely diagnosis and treatment, if not some cases will develop breast deformity and some others will be borderline or malignant....
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PMID: 20077881
PDF is available here.
PDF is available here.
Abstract
Phyllodes tumour is an uncommon fibro epithelial tumour of breast that often presents clinically as a rapidly enlarging lump. On mammography it appears as a soft tissue density well circumscribed mass. Ultrasound shows it to be a solid hypoechoic mass with small cystic spaces. A case of malignant ph...
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PMID: 19889271
PDF is available here.
PDF is available here.
Asian Journal of Surgery (32)4 2009
Abstract
The mean age of the patients was 45 +/- 7 years and the mean duration of symptoms was 30 +/- 10 months. The mean tumour diameter was 10.5 +/- 5 cm. Preoperative diagnosis with fine needle aspiration cytology could be made in 72% of cases. Overall, 39 surgical procedures were performed (14 of which w...
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PMID: 19892625
PDF is available here.
PDF is available here.
Vojnosanitetski pregled (66)4 2009
Abstract
The patients were ranged per age from 30--62 years (mean 43.3 years, median 39 years). A total of 35 cases of MPT were included: 20 benign (57%), 6 borderline malignant (17%) and 9 malignant (26%). Twenty-two patients (62.8%) underwent segmental mastectomy, while 13 (37.2%) had total mastectomies. T...
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PMID: 19441158
PDF is available here.
PDF is available here.
Yonsei Medical Journal (50)1 2009
Abstract
We report a 65 year-old man with a large cystic phyllodes tumor of the prostate. The patient complained of abdominal discomfort and had a soft palpable mass. Computer tomography showed a solid and cystic mass in the pelvic fossa; the mass was adjacent only to the prostate. We excised the mass. Micro...
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PMID: 19259368
PDF is available here.
PDF is available here.
Abstract
We performed a mastectomy during which a tumour measuring 48 x 33 x 25 cm was resected. Histological examination revealed a borderline phyllodes tumour. Phyllodes tumours are rare fibroepithelial neoplasms of the breast and pre-operatively these are often difficult to differentiate from fibroadenoma...
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PMID: 20015419
PDF is available here.
PDF is available here.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (50)4 2009
Abstract
We assessed clinical aspects of 79 phyllodes tumors regarding patient's age and localization of the tumors. In 17 out of 79 cases, it has been performed FNA within the tumors with further cytological examination on the smears obtained. The median age of the patients was 46.07-year-old, being progres...
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PMID: 19942954
PDF is available here.
PDF is available here.
Human Pathology (40)1 2009
Abstract
The proteolytic destruction of cyclin B is an important event during cell division. Cyclin B proteolysis is triggered by the anaphase-promoting complex. Therefore, cell cycle dysregulation due to anaphase-promoting complex loss contributes to cell transformation and human carcinogenesis. This study...
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PMID: 18789487
PDF is available here.
PDF is available here.
Abstract
We talk about giant phyllodes tumors. Ultrasound, Mammography and FNA are not effective. A potentially useful diagnostic modality is MRI. Core tissue biopsy or incisional biopsy represent the preferred means of pre-operative diagnosis. Conservative treatment can be effective also in giant tumors dep...
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PMID: 20476682
PDF is available here.
PDF is available here.
Abstract
Phyllode tumors of the breast are fibroepithelial tumors similar to fibroadenomas but with a predominant conjunctive tissue component. They are rare with an incidence of less than 1% of all breast neoplasms. They can be divided in three categories: benign, borderline, malignant. The Authors report t...
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PMID: 20476683
PDF is available here.
PDF is available here.
Connecticut medicine (73)6 2009
Abstract
Our patient, a 59-year-old female, presented with a rapidly growing 9x12 cm breast mass. She underwent modified radical mastectomy followed by chemotherapy with carboplatin and docetaxel. She is free of disease one year after diagnosis. Clinicians should be aware of the aggressive behavior of this t...
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PMID: 19637664
PDF is available here.
PDF is available here.
Abstract
We have used comparative genomic hybridization to analyze chromosomal copy number changes in 36 cases of phyllodes tumors (including benign, borderline and malignant phyllodes tumors, 12 cases each). The average number of chromosome copy changes (range) in benign, borderline and malignant phyllodes...
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PMID: 18189161
PDF is available here.
PDF is available here.
Singapore medical journal (49)11 2008
Abstract
We describe a 51-year-old woman with a malignant phyllodes tumour with foci of intraductal carcinoma within the tumour and adjacent breast tissue. Though the carcinoma was found to be invasive based on the presence of carcinomatous lymph node metastasis, extensive sampling did not yield an invasive...
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PMID: 19037540
PDF is available here.
PDF is available here.
Abstract
We present a female patient, 55 years old with a giant phyllodes tumour (38 x 31 x 23 cm) of the breast. The breast reconstruction was done using a pedicled transverse rectus abdominis myocutaneous (TRAM) flap....
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PMID: 18042445
PDF is available here.
PDF is available here.
Modern Pathology (21)10 2008
Abstract
We examined stromal c-kit expression by immunohistochemistry in 68 cases comprising fibroadenomas, fibroadenomas with cellular stroma, and benign, borderline, and malignant phyllodes tumors. Membrane staining was identified in the epithelium of 82% of cases, representing all diagnostic categories in...
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PMID: 18500266
PDF is available here.
PDF is available here.
Abstract
Breast MRI is recommended for preoperative evaluation of the newly diagnosed breast cancer patient....
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PMID: 18436185
PDF is available here.
PDF is available here.
No association of mouse mammary tumor virus-related retrovirus with Japanese cases of breast cancer.
Abstract
Mouse mammary tumor virus (MMTV) is the causative agent of breast tumors in mice. Recently, DNA sequences homologous or closely related to MMTV env gene have been specifically detected in breast cancer tissue from significant numbers of American, Australian, and Tunisian women, suggesting a viral et...
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PMID: 18551605
PDF is available here.
PDF is available here.
Abstract
Malignant phyllodes tumors of the breast local recurrence rates are 15% or greater for patients with tumors >2 cm treated by lumpectomy alone and tumors >10 cm treated by mastectomy alone. Adjuvant radiation therapy should be evaluated for these patients. This may be especially important because our...
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PMID: 18234448
PDF is available here.
PDF is available here.
The Breast (17)3 2008
Abstract
We present a series of 7 patients with phyllodes tumors who were treated with mastectomy and immediate breast reconstruction. Mastectomy was conventional in 4 patients and skin sparing in 3. Reconstruction was performed with latissimus dorsi (LD) musculocutaneous flap in 4 patients and transverse re...
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PMID: 18155550
PDF is available here.
PDF is available here.
Abstract
Retrospective analysis of 5270 patients with primary breast neoplasms revealed 33 patients. In the histopathological analysis, tumour grade was classified as benign in 40%, borderline in 27% and malignant in 33% of patients. Breast conserving surgery was conducted in 58% of the patients, mastectomy...
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PMID: 17868973
PDF is available here.
PDF is available here.
Abstract
Microscopically, the prostatic tumor showed elongated ducts and cellular stroma. Lung biopsy was composed of stromal cells with enlarged, hyperchromatic nuclei. CONCLUSION: This case represents a typical low grade prostatic phyllodes tumor to lung. Grading of these neoplasm is not always of value to...
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PMID: 18709826
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe a case of STUMP. A 42-year-old male was seen at a hospital with the chief complaint of elevated levels of prostate specific antigen. Since digital examination revealed abnormal findings in the prostate, then he was referred to our hospital. We diagnosed STUMP by ultra-sound-guided needle...
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PMID: 18546866
PDF is available here.
PDF is available here.
Abstract
We examined phyllodes tumors initially called fibroadenoma for features that may accurately classify the tumor as phyllodes tumor on the first biopsy specimen. The phyllodes tumors initially called fibroadenoma for features that may accurately classify the tumor as phyllodes tumors on the first biop...
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PMID: 18417670
PDF is available here.
PDF is available here.
Journal of Pathology (214)5 2008
Abstract
We also identified one p16INK4a mutation and evidence of methylation of p16INK4a in malignant PTs. Our evidence shows that inactivation of this gene is important in the development of malignant PTs. In selected PTs, multiple areas of stroma were isolated and analysed separately by array-CGH. We foun...
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PMID: 18288784
PDF is available here.
PDF is available here.
Archives of Surgery (143)2 2008
Abstract
Saudi medical journal (29)2 2008
Abstract
Of 1050 breast specimens received, 722 (68.8%) were benign. Fibroadenoma was the most common lesion with 318 cases (44%), occurring at a mean age of 16-32 years. Next was fibrocystic changes with 165 cases (22.9%) at a mean age of 23-45 years. Normal breast in the axillary tail region was seen in 32...
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PMID: 18246234
PDF is available here.
PDF is available here.
Abstract
This study showed that phyllodes tumor patients with no RD after treatment have better local control. Benign tumors have a good prognosis after surgery alone. In borderline and malignant tumors, TM had better results than BCS. Thus, in these forms adjuvant RT should be considered according to histol...
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PMID: 17931796
PDF is available here.
PDF is available here.
Breast Journal (14)2 2008
Abstract
Breast Journal (14)1 2008
Abstract
Breast Journal (14)2 2008
Abstract
Abstract
There are very few reports concerning the presence of malignant cystosarcoma phyllodes (CSP) in breasts of pregnant women. In the hereby described case, a 28-year-old woman presented in our department with huge (18 x 11 x 8 cm) tumor of left breast, 2 weeks after labor. The patient discovered a tumo...
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PMID: 17892454
PDF is available here.
PDF is available here.
Abstract
We describe a family with a history of cancer suggestive of the Li-Fraumeni syndrome (LFS). A 27-year-old woman suffered at 17 years of age from phyllodes breast tumor and was shown to carry a germline mutation in the TP53 gene. Two years after testing, she became pregnant and was offered prenatal d...
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PMID: 18068537
PDF is available here.
PDF is available here.
Surgery Today (38)1 2008
Abstract
We report a case of PT with an intraductal carcinoma component, which grew rapidly to a huge size in 3 months. Histologically, the stromal element showed mild to moderate cellularity with few mitoses and mild nuclear atypia. The epithelial element consisted of irregularly dilated ducts with a phyllo...
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PMID: 18085361
PDF is available here.
PDF is available here.
Histopathology (52)1 2008
Abstract
This article reviews recent advances in the diagnosis of these three unusual tumours of the breast. Spindle cell carcinoma needs to be considered in the differential diagnosis of many mammary spindle cell lesions: it is important to be aware of the wide range of appearances, including the recently d...
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PMID: 18171416
PDF is available here.
PDF is available here.
Abstract
Phyllodes tumor (PT) is an uncommon tumor in adolescent girls and young women. A case of PT in a 14-year-old girl is reported. The clinical examination showed a painless tumor that had grown during 10 months. Total excision of the mass with wide margin was performed. The diagnosis, behavior, and tre...
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PMID: 18231958
PDF is available here.
PDF is available here.