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Carcinoma, Endometrioid (0):
Recent article
Carcinoma, Endometrioid
Abstract
Endometrial serous carcinomas constitute no more than 10% of endometrial adenocarcinomas, but frequently present at an advanced stage and have a significantly worse prognosis than the more common low-grade and intermediate-grade endometrioid adenocarcinomas. The neoplasm's potential for rapid tumor...
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PMID: 21164282
PDF is available here.
PDF is available here.
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Abstract
Myometrial invasion is an independent prognostic parameter of the endometrioid carcinomas which correlates with the risk of metastasis to pelvic and/or paraaortic lymph nodes. Recognition of myometrial invasion is sometimes difficult. In fact, myoinvasion is overdiagnosed in routine practice in as m...
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PMID: 20962622
PDF is available here.
PDF is available here.
Abstract
Endometrioid adenocarcinoma (EAC) of the uterus can show varying patterns of invasion, 1 of which, "MELF," is characterized by the presence of microcystic, elongated, and fragmented glands. However, at present, little is known of the functional alterations in neoplastic cells that are associated wit...
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PMID: 20881856
PDF is available here.
PDF is available here.
Abstract
We thus examined a total of 103 consecutive cases of invasive uterine endometrioid adenocarcinoma in an attempt to determine if an association exists between the stromal reactions and other well-defined histologic and clinical prognostic factors. We found that the presence of a desmoplastic reaction...
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PMID: 20881855
PDF is available here.
PDF is available here.
Anticancer Research (30)10 2010
Abstract
We investigated the expression of BAG-1, ERa and PRA isomorphs in endometrioid adenocarcinoma and we correlated them with clinicopathological findings of the tumor. Fresh endometrial tissues were obtained from 33 patients with endometrial carcinoma and 191 paraffin-embedded tissues were analyzed by...
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PMID: 21036726
PDF is available here.
PDF is available here.
Abstract
We have focused our review on lymph node disease in patients with early endometrial cancer. We report on the important issues surrounding lymphadenectomy in endometrial cancer and the results of a recent large randomized trial that do not indicate a benefit of surgical staging. Other issues, includi...
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PMID: 20531186
PDF is available here.
PDF is available here.
Oncology Reports (24)2 2010
Abstract
Human endometrial cancer expresses both the known estrogen receptors (ER-alpha and ER-beta). The significance of the relative expression of both ER subtypes in endometrial adenocarcinomas remains to be clarified and the usefulness of the determination of the receptor status in endometrial cancer pat...
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PMID: 20596625
PDF is available here.
PDF is available here.
Abstract
Reproducible diagnosis of ovarian carcinoma cell types is critical for cell type-specific treatment. The purpose of this study was to test the reproducibility of cell type diagnosis across Canada. Analysis of the interobserver reproducibility of histologic tumor type was performed among 6 pathologis...
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PMID: 20505499
PDF is available here.
PDF is available here.
Abstract
We describe a metastasis of an ovarian endometrioid adenocarcinoma with shadow cells to the skin that was initially misinterpreted as a pilomatricoma. We compare the histology of the ovarian neoplasm to 21 pilomatricomas. This is the first reported case of a cutaneous metastasis of a visceral neopla...
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PMID: 20526175
PDF is available here.
PDF is available here.
Abstract
During carcinogenesis, loss of intracellular cohesion is observed among cancer cells with altered expression of such adhesion molecules as E-cadherin and beta-catenin, and aberrant expression and cellular location of intercellular gap junction proteins-connexins. The aim of this study was to evaluat...
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PMID: 20567150
PDF is available here.
PDF is available here.
Abstract
We selected 180 endometrial carcinomas of SC, EC, or CCC type. No mixed carcinomas were included in the study. We chose the following immunohistochemical markers, estrogen receptor (ER), insulin-like growth factor 2 mRNA-binding protein 3 (IMP3), p16, p53, progesterone receptor (PR), and phosphatase...
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PMID: 20567148
PDF is available here.
PDF is available here.
Abstract
We report a case of massive intra-abdominal undifferentiated carcinoma derived from a tiny well-differentiated endometrioid adenocarcinoma of the ovary. The patient, a 56-year-old woman, who presented with a large intra-abdominal mass, underwent cytoreductive surgery with hysterectomy and bilateral...
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PMID: 20567143
PDF is available here.
PDF is available here.
Abstract
This treatment has excellent survival rates with acceptable morbidity, and recurrence is mostly distant....
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PMID: 20686374
PDF is available here.
PDF is available here.
Oncology Reports (23)5 2010
Abstract
I in 71 cases (64.5%), II in 5 (4.5%), III in 28 (25.5%), and IV in 6 (5.5%). Staining intensity of tumor cells was divided into two categories; tumor cells with no to weak and moderate to strong membrane staining. The intensity of CDCP1 expression in each case was defined by the staining of major p...
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PMID: 20372833
PDF is available here.
PDF is available here.
Abstract
We reviewed full slide sets of 1009 cases of 2555 patients diagnosed with ovarian carcinoma that were referred to the British Columbia Cancer Agency over a 16-year period (1984 to 2000). On the basis of the reviewed cases we extrapolated the distribution of tumor type in low-stage (I/II) and high-st...
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PMID: 20407318
PDF is available here.
PDF is available here.
Abstract
We used genome-wide microarray-based comparative genomic hybridization (aCGH) technology to characterize five of the more commonly used endometrial cancer cell lines. We detected DNA copy-number gains in chromosomal regions 2q, 3p, 3q, 5q, 7p, 17q, and 19q in all five cell lines. Other common sites...
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PMID: 20218740
PDF is available here.
PDF is available here.
Abstract
Because serum concentrations of CA-125 can be elevated in various malignancies, it is obvious that it is neither specific nor accurately diagnostic for endometrial tumors. What is more, the distinct effects of physiological factors on prolactin secretion shadow the credibility of this hormone in ear...
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PMID: 19777250
PDF is available here.
PDF is available here.
Abstract
Chylous ascites should be included in differential diagnosis of abdominal distention after surgical retroperitoneal approach or radiotherapy. Most of the patients may have their chylous ascites successfully treated with conservative management. However, the best policy is to prevent chylous complica...
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PMID: 19685063
PDF is available here.
PDF is available here.
Ginekologia polska (81)3 2010
Abstract
Histological examination revealed that there were 27 cases of serous cancers (50%), 15 cases of mucinous cancer (28.3%) and 11 endometrioid cancers (20.7%). In 41.5% (n = 22) cases of EOC no NRP-1 staining was found, a weak (+) or strong (++) staining were found in 13 (24.5%) and 18 tumors, respecti...
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PMID: 20486537
PDF is available here.
PDF is available here.
Collegium Antropologicum (34)1 2010
Abstract
Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for. The aim of the present study was to assess the value of morphometri...
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PMID: 20437635
PDF is available here.
PDF is available here.
Collegium Antropologicum (34)1 2010
Abstract
The aim of this study was to evaluate medical and economic justification of vaginal smears as a part of primary screening for cervical carcinoma and its precursors. Study included 245.048 participants whose VCE (vaginal, cervical, endocervical) smears were examined at Department of clinical cytology...
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PMID: 20437636
PDF is available here.
PDF is available here.
Abstract
We selected 14 cases of endometrial endometrioid adenocarcinomas involving the cervix with complete pathology material available from the years between 1968 and 2004. Immunohistochemical studies for vimentin, carcinoembryonic antigen, estrogen receptor, progesterone receptor, and p16 were performed...
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PMID: 20173500
PDF is available here.
PDF is available here.
Gynecologic Oncology (116)3 2010
Abstract
These results, based on a larger series, support our previous data: Paclitaxel plus RT may represent an effective and well-tolerated treatment in high-risk endometrial cancer patients....
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PMID: 20022359
PDF is available here.
PDF is available here.
Abstract
The results of the study demonstrate that TP53 gene mutations occur in some of endometrioid endometrial cancers in the presence of PTEN gene mutations, suggesting that both these genes participate in the development of these tumors....
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PMID: 20169661
PDF is available here.
PDF is available here.
Abstract
Diagnostic criteria for WDA are proposed regarding histologic features predicting the presence of myometrial or endometrial stromal invasion by proliferating glands, or aggressive behavior. SUMMARY: Most useful diagnostic histological features in WDA, such as cribriform, labyrinthine, and confluent...
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PMID: 19904204
PDF is available here.
PDF is available here.
Abstract
to analyze the prognostic value of microsatellite instability (MSI) in a population-based study of FIGO stage 1-4 endometrial endometrioid adenocarcinomas.
survival analysis in 273 patients of MSI status and clinico-pathologic features. Using a highly sensitive pentap...
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PMID: 21079294
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
|
PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
|
PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
|
PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
|
PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
|
PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Abstract
These results illustrate that VEGF-D over-expression has differential effects on the uterine vasculature. These effects may facilitate VEGF-D's ability to promote endometrial cancer metastasis and disease progression....
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PMID: 20615255
PDF is available here.
PDF is available here.
Abstract
The mean SUVmax of the primary endometrial cancer tumors was 17.6 (range, 3.04-34.74). There were significant correlations between the SUVmax of the primary tumor and the International Federation of Gynecology and Obstetrics (FIGO) grade (P < 0.001), maximum tumor size (P < 0.001), and glucose trans...
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PMID: 20130510
PDF is available here.
PDF is available here.
Abstract
I uterine clear cell carcinoma (UCCC) treated with and without adjuvant therapy, and to compare the outcomes in these patients to that of matched controls, patients with Stage I, grade 3, endometrioid adenocarcinoma of the endometrium (EC).
Patients with FIGO Stage I UCCC who underwent comprehensive...
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PMID: 21077469
PDF is available here.
PDF is available here.
Abstract
We report the muscle as an unusual site of metastasis. CASE: A 69-year-old woman underwent surgery for FIGO Stage IA, grade 1 endometrioid adenocarcinoma of the endometrium. After four years she had local relapse without response to chemoradiation, requiring pelvic exanteration. Three years later sh...
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PMID: 20349796
PDF is available here.
PDF is available here.
Multinucleate (histiocytic) giant cells in endometrioid adenocarcinoma of the ovary: a rare finding.
Abstract
Abstract
We report a case of grade 2 endometrioid adenocarcinoma arising from an adenomyotic focus in the uterus....
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PMID: 21319528
PDF is available here.
PDF is available here.
Abstract
The abnormal expression of beta-catenin and overexpression of Glut-1 may be useful markers in distinguishing benign hyperplasia from EIN, whereas lack of PTEN expression is not an appropriate marker for a diagnosis of EIN....
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PMID: 20527231
PDF is available here.
PDF is available here.
Abstract
This study revealed that prevalence of endometrial polyp malignant transformation was < or = 2.84% in postmenopausal and symptomatic patients....
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PMID: 20527232
PDF is available here.
PDF is available here.
Revista Medico-Chirurgicala (114)1 2010
Abstract
Endometrial hyperplasia is a proliferation of the endometrium with increased number of glands and the change of the gland-stroma ratio. By histopathologic examination is now accepted the WHO classification. Atypical hyperplasia is accepted to be a precursor for endometrioid carcinoma. In order to fi...
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PMID: 20509298
PDF is available here.
PDF is available here.
Abstract
To investigate the usefulness of high-field MR diffusion-weighted imaging (DWI) in the diagnosis of endometrial carcinoma.
Thirty-five female patients with pathologically proven endometrial carcinoma, 10 patients with pathologically proven endometrial dysplasia and 41 normal volunteers were enrolled...
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PMID: 20137351
PDF is available here.
PDF is available here.
Virchows Archiv (456)1 2010
Abstract
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established fo...
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PMID: 19859732
PDF is available here.
PDF is available here.
Obstetrics & Gynecology (114)4 2009
Abstract
Mean age was 62.2 years (+/-11.6 years). Thirty-eight women (12%) had positive pelvic nodes. Seventy-five (23.7%) received adjuvant pelvic radiotherapy. Age older than 60, grade 3 tumor, deep myometrial invasion (greater than 50%), and cervical stromal involvement were associated with a higher risk...
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PMID: 19888029
PDF is available here.
PDF is available here.
Abstract
We describe here a patient with this condition and review the clinical and pathological features of these tumors. A 48-yr-old woman complaining of severe dysmenorrhea was referred for investigation of a pelvic mass. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. His...
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PMID: 19654969
PDF is available here.
PDF is available here.
Der Pathologe (30)4 2009
Abstract
Malignant mixed Mullerian tumors (MMMT; carcinosarcomas) are rare epithelial-mesenchymal tumors. With an overall survival rate of 30%-40% the prognosis is much worse compared to high grade endometrioid or serous/clear cell carcinomas. Depending on the histology of the mensenchymal components a disti...
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PMID: 19495763
PDF is available here.
PDF is available here.
Der Pathologe (30)4 2009
Abstract
I and type II carcinomas today. Both groups of tumors are clearly different with regard to conventional light microscopy, immunohistochemistry, molecular pathology and clinical features. Only type I carcinomas are associated with hyperestrogenism. The group of type I carcinomas consists of endometri...
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PMID: 19495762
PDF is available here.
PDF is available here.
Journal of Clinical Oncology (27)19 2009
Abstract
We sought to determine the frequency and clinicopathologic significance of ATR mutations in patients with endometrioid endometrial cancer. PATIENTS AND METHODS The ATR exon 10 A10 repeat was analyzed by direct sequencing in 141 tumors with microsatellite instability (MSI-positive) and 107 microsatel...
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PMID: 19470935
PDF is available here.
PDF is available here.
Abstract
The results were assessed using the weighted kappa statistic. The mean intraobserver kappa value was 0.86. The mean interobserver kappa values by diagnostic category were as follows: simple hyperplasia without atypia: 0.74; complex hyperplasia without atypia: 0.33; atypical hyperplasia: 0.34, and we...
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PMID: 19566355
PDF is available here.
PDF is available here.
Abstract
The median age and body mass index were 56 years (range, 28 to 75) and 25.5 kg/m(2) (range, 21.3 to 37.2). The median operating time, estimated blood loss, and length of hospital stay were 142 minutes (range, 110 to 410), 215 mL (range, 100 to 700), and 7 days (range, 3 to 19), respectively. No conv...
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PMID: 19652848
PDF is available here.
PDF is available here.
Abstract
We updated to 2006 data on second cancers in women diagnosed with invasive and borderline ovarian cancer in the Swiss canton of Vaud. Between 1974 and 2006, 304 borderline and 1530 invasive first ovarian tumours were abstracted from the Vaud Cancer Registry database and followed up till the end of 2...
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PMID: 19491608
PDF is available here.
PDF is available here.
Zhonghua Yixue Zazhi (89)19 2009
Abstract
A total of 111 differentially expressed miRNA were found, including 68 over-expression miRNA and 43 low-expression. CONCLUSION: MiRNA may play important roles in tumorigenesis of endometrioid adenocarcinoma. The study of miRNA contributes to elucidate the molecular mechanism of endometrial cancer....
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PMID: 19615196
PDF is available here.
PDF is available here.