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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Endometrial Neoplasms (2):
Recent article
Endometrial Neoplasms
Abstract
Based on hysterosopy, 31 (72.1%) patients were classified as G1, G2 7 (16.3%) and G3 5 (11.6%) respective. In grade 1 the concordance rate was 77.4% of cases, in grade 2 it was in 14.3% of cases and in grade 3 it was in 80.0% of cases. In hysterosocpy samples the p53 expression was found in 23 (53.5...
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PMID: 20731294
PDF is available here.
PDF is available here.
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Abstract
Our study suggest that tested cytokines (HGFs) can be clinically useful in diagnostic of endometrial cancer patients. M-CSF can be clinically useful in differentiation of endometrial cancer and myoma uteri. Furthermore SCF and M-CSF showed usefulness in primary diagnostic of cancer uteri, especially...
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PMID: 20568396
PDF is available here.
PDF is available here.
Modern Pathology (23)5 2010
Abstract
We showed that PIK3CA and p53 alterations in uterine endometrial carcinomas correlate with poor prognosis. However, the contribution of phosphatidylinositol 3-kinase (PI3K) -AKT deregulation to endometrial carcinogenesis is not completely understood. The purpose of this study was to analyze alterati...
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PMID: 20173732
PDF is available here.
PDF is available here.
Abstract
For IRS-2 G1057D polymorphism, there was a significant difference in genotype distribution and allele frequency between endometrial cancer patients and controls (p < 0.001). The risk for endometrial cancer was 4.87 times higher in the individuals with the IRS-2 DD genotype compared to the GG genotyp...
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PMID: 20184486
PDF is available here.
PDF is available here.
Abstract
Biopsy specimens showing AEH, particularly atypical complex hyperplasia, are associated with a risk of coexisting endometrial carcinoma. When considering management strategies for women with a biopsy diagnosis of AEH, clinicians should take into account the considerable rate of concurrent endometria...
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PMID: 20185225
PDF is available here.
PDF is available here.
Anticancer Research (30)5 2010
Abstract
Expression of TKTL1, GLUT1 and pAKT was significantly increased in endometrial carcinomas as compared to benign endometrial tissue. There was a significantly weaker TKTL1 expression in highly differentiated G1 tumors. In the human endometrial cancer cell lines Ishikawa and HEC-1A, TKTL1 mRNA was cle...
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PMID: 20592357
PDF is available here.
PDF is available here.
Anticancer Research (30)5 2010
Abstract
BMI-I was significantly (p<0.05) overexpressed in human breast, ovarian, endometrial and cervical cancer specimens as compared to benign controls. BMI-I expression was also more pronounced in the ovarian cancer samples as demonstrated by Western blot analysis. In human breast cancer samples, BMI-I e...
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PMID: 20592341
PDF is available here.
PDF is available here.
Abstract
The purpose of this study was to investigate the role of NAC1 in the development of endometrial cancer. NAC1 expression and localization were assessed with immunohistochemistry in the normal cyclic human endometrium, hyperplastic endometrium, and endometrial cancer. Expression of NAC1 in the glandul...
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PMID: 20372782
PDF is available here.
PDF is available here.
Abstract
We explored the effects of doxorubicin (DOX), cisplatin (CDDP) and 5-fluorouracil (5-FU) on four types of endometrioid adenocarcinoma cell lines (HEC-1A, HEC-1B, Ishikawa, KLE) correlating the drug-induced increases in phosphorylated H2AX (gammaH2AX) with cell cycle phase, induction of apoptosis and...
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PMID: 20372780
PDF is available here.
PDF is available here.
Abstract
Changes of the Ki-67 index during NACT are associated with progression-free survival. If confirmed in prospective trials, an increasing Ki-67 index during preoperative treatment may serve as an indicator for resistance to chemotherapy....
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PMID: 20442588
PDF is available here.
PDF is available here.
Abstract
Diaphragmatic surgery during interval debulking enhances optimal cytoreduction rates and improves survival with acceptable and manageable morbidity. In patients with thick (>4 mm) or large (>1 cm) lesions, stripping the diaphragm or full-thickness resection of the diaphragmatic muscle is preferred....
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PMID: 20686373
PDF is available here.
PDF is available here.
Abstract
Laparoscopic surgery is a safe and reliable alternative to open surgery in the management of early endometrial cancer patients, with significantly reduced hospital stay and complications, especially in those patients with an elevated BMI....
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PMID: 20686375
PDF is available here.
PDF is available here.
Abstract
Ultrasonography had high sensitivity and an excellent negative likelihood ratio in this study. Further studies are needed, and ultrasonography should be compared with clinical follow-up, diagnostic hysteroscopy, or endometrial biopsy alone....
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PMID: 20686377
PDF is available here.
PDF is available here.
Abstract
We characterized for the first time in a clinical setting a new but rare exon6-skipping mRNA splicing isoform of YT521. Furthermore, we identified YT521 as a potential new independent prognostic factor for patients with EC: the lack of YT521 protein in tumor cells was highly predictive for a poor ov...
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PMID: 20686370
PDF is available here.
PDF is available here.
Abstract
The KLK10 SNPs investigated were not associated with ovarian cancer survival. However, steroid hormone treatment of ovarian cell lines showed KLK10 up-regulation in response to estrogen and estrogen plus progesterone treatments in the aggressive cell line PEO1 and affirmed a role for KLK10 in aggres...
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PMID: 20686372
PDF is available here.
PDF is available here.
Abstract
This treatment has excellent survival rates with acceptable morbidity, and recurrence is mostly distant....
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PMID: 20686374
PDF is available here.
PDF is available here.
Abstract
The overexpression of p53 and Ki-67 seems to indicate a more malignant phenotype, whereas bcl-2 expression in dependence of steroid receptor positivity could contribute to the identification of high-risk tumors....
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PMID: 20686376
PDF is available here.
PDF is available here.
Oncology Reports (23)5 2010
Abstract
I in 71 cases (64.5%), II in 5 (4.5%), III in 28 (25.5%), and IV in 6 (5.5%). Staining intensity of tumor cells was divided into two categories; tumor cells with no to weak and moderate to strong membrane staining. The intensity of CDCP1 expression in each case was defined by the staining of major p...
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PMID: 20372833
PDF is available here.
PDF is available here.
Chinese Medical Journal (123)9 2010
Abstract
Triptorelin and GnRH-II can promote apoptosis rate and inhibit cell proliferation of estrogen receptor-negative endometrial carcinoma cells in a dose-dependent manner. PTEN gene can inhibit the effects of Triptorelin or GnRH-II on human endometrial carcinoma cells....
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PMID: 20529558
PDF is available here.
PDF is available here.
Gynecologic Oncology (117)2 2010
Abstract
Subgroups of patients with non-endometrioid endometrial cancer and defective MMR may have improved survival after adjuvant radiotherapy. Patients with advanced stage endometrial cancer and defects in mismatch repair may receive less benefit from adjuvant chemotherapy.
Copyright (c) 2010 Elsevier Inc...
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PMID: 20153885
PDF is available here.
PDF is available here.
Gynecologic Oncology (117)2 2010
Abstract
Clinical trials are planned to further explore how to best incorporate novel agents into the current treatment algorithm with the aim to improve the options in both first- and second-line treatments for women with endometrial adenocarcinomas.
Copyright (c) 2010 Elsevier Inc. All rights reserved....
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PMID: 20223510
PDF is available here.
PDF is available here.
Gynecologic Oncology (117)2 2010
Abstract
275 cases were identified-102 patients with robotic-assisted staging and 173 patients with traditional laparoscopic staging. There was no significant difference in the rate of major complications between groups (p=0.13). The mean operative time was longer in cases of robotic-assisted staging (237 mi...
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PMID: 20144471
PDF is available here.
PDF is available here.
American Surgeon (76)4 2010
Abstract
Abstract
We used genome-wide microarray-based comparative genomic hybridization (aCGH) technology to characterize five of the more commonly used endometrial cancer cell lines. We detected DNA copy-number gains in chromosomal regions 2q, 3p, 3q, 5q, 7p, 17q, and 19q in all five cell lines. Other common sites...
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PMID: 20218740
PDF is available here.
PDF is available here.
Abstract