Abstract
These results indicate that ATRA within a certain range of concentration could reversibly induce the expression of FR-β in a dosage- and cell type-dependent manner, and its action in KG-1 cells might be associated with the signal transduction of retinoid receptor RARα and RARγ, rather than RARβ...
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PMID: 20632143
PDF is available here.
Abstract
Our study aimed to delineate the immunophenotype of these tumors and to verify whether their morphology reflects true sex cord-like differentiation.
Representative paraffin blocks from 12 UTROSCTs were selected after confirmation of the diagnosis. Cords and/or trabeculae were seen in all tumors, whe...
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PMID: 21084963
PDF is available here.
Abstract
We report a case of a 45-year-old woman with DM who underwent laparotomy for uterine cancer under general anesthesia combined with epidural anesthesia. Epidural catheter was placed from T 11-12, and anesthesia was inducted with propofol and remifentanil (RF). We administered rocuronium bromide (RB)...
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PMID: 21077314
PDF is available here.
Abstract
We observed a large 236 cm3 tumor spread over the subcutaneous tissue of the superior sagittal sinus, pressing the brain out of the dura mater and causing bone destruction. As a result of our findings, we began stereotactic Cyberknife radiotherapy delivered in 7 fractions. At the follow up visit one...
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PMID: 21081813
PDF is available here.
Abstract
We present the clinicopathologic features of the second case of cellular blue nevus arising in the myometrium. The patient was a 48-year-old woman who underwent a hysterectomy with bilateral salpingo-oophorectomy for uterine leiomyomas. On gross examination, the uterus showed a subserosal, 1.0×0.5...
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PMID: 20881851
PDF is available here.
Abstract
To evaluate the influence of BMI on the prevalence of fibroids and uterine weight. Uterine pathology specimens of all the women who underwent hysterectomy for benign indications from 1995 to 2002 were studied. Patient characteristics such as age, race, body mass index (BMI), and parity were collecte...
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PMID: 20881854
PDF is available here.
Abstract
Endometrioid adenocarcinoma (EAC) of the uterus can show varying patterns of invasion, 1 of which, "MELF," is characterized by the presence of microcystic, elongated, and fragmented glands. However, at present, little is known of the functional alterations in neoplastic cells that are associated wit...
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PMID: 20881856
PDF is available here.
Abstract
We thus examined a total of 103 consecutive cases of invasive uterine endometrioid adenocarcinoma in an attempt to determine if an association exists between the stromal reactions and other well-defined histologic and clinical prognostic factors. We found that the presence of a desmoplastic reaction...
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PMID: 20881855
PDF is available here.
Abstract
We report a case and describe diagnostic criteria and differential diagnoses....
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PMID: 21040666
PDF is available here.
Abstract
I and II have been combined. The number and morphology of the involved nodes have been taken into account, and the bilaterality of positive nodes has been discounted. In cervical cancer Stage 0 has been deleted and substages in Stage IIA have been included. In endometrial cancer Stage IA and IB have...
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PMID: 21117307
PDF is available here.
Abstract
We conclude that this technique is safe and effective in treating human solid tumors. HIFU is a promising technique. Most importantly, HIFU offers patients another alternative when those patients have no other treatment available....
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PMID: 21191835
PDF is available here.
Abstract
OBJECTIVE: To report a case of cancer of the colon which presented as secondaries to the ovaries. METHOD: Case report. SUMMARY: The case presented is that of a 39-year-old female who presented with lower abdominal pain and a multinodular pelvic mass which led to an initial diagnosis of multiple uter...
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PMID: 20857797
PDF is available here.
Abstract
We investigated biological functions and inhibitory effects of HAI-1 and HAI-2 using uterine LMS cell line SK-LMS-1 and SKN. The expression levels of HAI-1 and HAI-2 were significantly decreased in uterine LMS specimens relative to corresponding uterine normal smooth muscle and leiomyoma specimens....
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PMID: 20664929
PDF is available here.
Abstract
Uterine clear cell carcinoma (UCC) and uterine papillary serous carcinoma (UPSC) are rare entities that differ in clinical behavior from endometrial adenocarcinoma. Compared with endometrioid adenocarcinoma, they more often metastasize early and more commonly in the upper abdomen including the oment...
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PMID: 20944161
PDF is available here.
Abstract
Of 21 patients examined, 13 patients were eligible to enter this pilot study. Only one patient had lymph node metastasis, which was preoperatively detected by FDG-PET scan. Additionally, another patient was considered to have lymph node metastasis according to increased focal FDG uptake; however, al...
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PMID: 20944170
PDF is available here.
Abstract
We describe here the procedure employed to successfully remove this filter....
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PMID: 20679682
PDF is available here.
Abstract
A 39-year-old woman underwent transcervical resection (TCR) of submucosal uterus myoma. Induction and maintenance of anesthesia were managed with total intravenous anesthesia using propofol, remifentanil and rocuronium bromide. Patient had stable condition from the anesthesia induction until 75 minu...
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PMID: 20715527
PDF is available here.
Abstract
We report that an intrauterine contraceptive device (IUCD) embedded within intrauterine tumour (submucous myoma) in a postmenopausal woman was misdiagnosed, definitively diagnosed and successfully removed with hysteroscopic resection. Hysteroscopy and hysteroscopic resection of the submucous myoma w...
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PMID: 20716271
PDF is available here.
Abstract
The objective of this retrospective study was to evaluate the safety, intra-operative and post-operative morbidity of laparoscopic approach for myomectomy.
The total 1001 subjects who underwent endoscopic surgery over a 16-year period were studied retrospectively. All the data were collected regardi...
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PMID: 20716269
PDF is available here.
Abstract
The treatment of acute leukemia is usually similar in women and men. The outcome is also generally the same. However, diagnosis in women poses additional challenges in clinical practice such as leukemia following breast or ovarian cancers, prevention of abnormal uterine bleeding in premenopausal fem...
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PMID: 20435579
PDF is available here.
Abstract
We found that TWEAK gene expression was down-regulated and Fn14 gene expression was up-regulated in human endometrial cancer specimens compared with that in normal endometrial specimens; TWEAK acting on Fn14 decreased cell viability by inducing apoptosis through caspase pathways in endometrial cance...
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PMID: 20189297
PDF is available here.
Abstract
Intravenous leiomyomatosis is a rare smooth muscle tumour that arises from the myometrium and grows into the extrauterine venous system. It typically can extend into the vena cava inferior and even the cardiac chambers. This can lead to life threatening obstruction of cardiac valves. The only effect...
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PMID: 20802437
PDF is available here.
Abstract
BACKGROUND: Pyomyoma (suppurative leiomyoma) is a rare disease that is a serious complication. Most cases have occurred in pregnant or postmenopausal women. CASE: A perimenopausal woman presented with fever and shoulder pain. She had no predisposing factors or history of leiomyoma. Ultrasonographic...
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PMID: 20664442
PDF is available here.
Abstract
We describe a unique case of urticaria associated with a Salmonella infection of uterine leiomyomas. CASE: A 55-year-old woman with a known history of uterine leiomyomas and a chief complaint of recurrent small and coalescing urticarial lesions confined to the abdomen presented with an 18-year histo...
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PMID: 20664429
PDF is available here.
Abstract
We report 3 cases of a hitherto undescribed phenomenon in women aged 46 to 49 in which there was replacement of the myometrium or cervical stroma by an accumulation of hypocellular myxoid stromal material containing bland spindle-shaped cells and small blood vessels. In all cases, this change was co...
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PMID: 20567149
PDF is available here.
Abstract
I present a rare case of a 53-year-old female who consulted for pelvic pain and abnormal uterine bleeding. The pelvic ultrasound revealed intramural and submucous uterine leiomyomas, and she underwent hysterectomy and bilateral salpingo-oophorectomy. Gross examination showed several paratubal cysts,...
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PMID: 20567145
PDF is available here.
Abstract
To explore the pattern of benign gynecologic diseases in patients treated with tamoxifen for breast cancer.
A total of 163 cases with breast cancer were followed up by gynecologists. The incidence rates of several benign gynecologic conditions were determined and were compared among women receiving...
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PMID: 20979888
PDF is available here.
Brian Teague,
Michael S Waterman,
Steven Goldstein,
Konstantinos Potamousis,
Shiguo Zhou,
Susan Reslewic,
Deepayan Sarkar,
Anton Valouev,
Christopher Churas,
Jeffrey M Kidd,
Scott Kohn,
Rodney Runnheim,
Casey Lamers,
Dan Forrest,
Michael A Newton,
Evan E Eichler,
Marijo Kent-First,
Urvashi Surti,
Miron Livny and
David C Schwartz
Abstract
We addressed this gap with Optical Mapping, a high-throughput, high-resolution single-molecule system for studying genome structure. We used Optical Mapping to create genome-wide restriction maps of a complete hydatidiform mole and three lymphoblast-derived cell lines, and we validated the approach...
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PMID: 20534489
PDF is available here.
Abstract
BACKGROUND: Fibroids remain the commonest pelvic tumour seen in women with myomectomy being the major form of treatment in our environment. Techniques to minimize blood loss will reduce patient morbidity and the need for blood transfusions. One such technique is the use of a tourniquet during myomec...
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PMID: 20499747
PDF is available here.
Abstract
NF is probably a specific substrate of BCRP, and BCRP has a major active role in NF transport in JAr cells. For the first time, we showed, that P-gp, MRPs, and the OATP2B1, probably have a negligible contribution to NF transport in JAr cells....
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PMID: 19924425
PDF is available here.
Abstract
Uterine artery embolization (UAE) is becoming a common treatment for symptomatic leiomyoma. Several pregnancies following UAE have been reported. However, reports are still limited and the risk of complications remains unknown.
A primigravida conceived after UAE for leiomyoma. She delivered spontane...
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PMID: 20708528
PDF is available here.
Abstract
A 27-year-old woman, gravida 0, presented with uterine and cutaneous leiomyomata. Genetic testing confirmed hereditary leiomyomatosis and renal cell cancer syndrome, an autosomal dominant disorder caused by germline mutations in the fumarate hydratase gene. Specific screening guidelines do not exist...
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PMID: 20510956
PDF is available here.
Abstract
Common gynecologic conditions and surgeries may vary significantly by race or ethnicity. Uterine fibroid tumors are more prevalent in black women, and black women may have larger, more numerous fibroid tumors that cause worse symptoms and greater myomectomy complications. Some, but not all, studies...
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PMID: 20430357
PDF is available here.
Abstract
Fifty-five patients were entered onto the study with nine being excluded from analysis, leaving 46 evaluable for analysis. Treatment was well tolerated with expected hematologic toxicity and minimal nonhematologic grade 4 toxicity (one cardiovascular and two pain) with 59% of patients completing six...
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PMID: 20421537
PDF is available here.
Abstract
One hundred thirteen patients completed at least one clinical follow-up. Twenty-four months after UAE, 50% +/- 15.2 (standard error) of the patients with partial infarction and 80% +/- 13.4 (standard error) of patients with almost complete infarction had undergone no reintervention. No patient with...
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PMID: 20392986
PDF is available here.
Abstract
Associations between leiomyoma with IGF2 and CDH1 polymorphism exist. Proportions of IGF2 exon 9*AA/AG/GG in and CDH1* CC/CT/TT in the groups were: group 1, 38/39.2/22.8% and 27.8/66.5/5.7%; group 2, 22.4/53.9/23.7% and 21.2/64.1/14.7. MPO, urokinase, XPA and XPD in both groups were non-significantl...
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PMID: 20651370
PDF is available here.
Abstract
We review evidence that uterine fibroids, specifically submucosal and intramural myomas, negatively impact fertility and are associated with adverse obstetrical outcomes such as: pain, preterm labor, placental abruption, malpresentation, postpartum hemorrhage, and cesarean section. Myomectomy perfor...
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PMID: 20595947
PDF is available here.
Abstract
The prevalence of uterine myomas during pregnancy is estimated to range from 0.3% to 2.6%. Although leiomyomas usually remain asymptomatic, in one often cases they may be complicated. The management of uterine fibroids during pregnancy is largely conservative and surgical removal is generally delaye...
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PMID: 21086740
PDF is available here.
Abstract
Aldosterone-induced ELT-3 leiomyoma cell proliferation and the expression of mineralocorticoid receptor (MR) were confirmed. Pre-incubating the cells with the MR blockers spironolactone or eplerenone effectively repressed aldosterone-induced and angiotensin II (Ang II)-induced cell proliferation. Tr...
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PMID: 20050763
PDF is available here.
Abstract
We present a 52-year-old female with recurrent episodes of urinary retention that was related to periods of menstruation. Pelvic magnetic resonance imaging revealed a markedly enlarged uterus with multiple fibroids. The patient had laparoscopic hysterectomy with postoperative resolution of patient's...
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PMID: 19924369
PDF is available here.
Abstract
Although our findings regarding cervical cancer mortality in Greece are encouraging, still more efforts are needed, particularly in preventing cervical cancer in younger women. The increasing trend of uterine corpus and ovarian cancer mortality in older women suggests that development of well-organi...
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PMID: 20686368
PDF is available here.
Abstract
This treatment has excellent survival rates with acceptable morbidity, and recurrence is mostly distant....
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PMID: 20686374
PDF is available here.
Abstract
This report discusses a pregnancy case following a series of two consecutive magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) procedures for the treatment of two different myomas in an individual patient. Both procedures were completed without adverse events, and the patient con...
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PMID: 20376901
PDF is available here.
Abstract
We refer to as familial recurrent hydatidiform moles. We use the term familial biparental hydatidiform moles (FBHMs) for cases in which the parental contribution to the moles has been investigated and found to be biparental. It is important to recognise, however, that in some apparently non-familial...
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PMID: 20171777
PDF is available here.
Abstract
The infection rates were 35.66% for patients with cervicitis, 54.61% for those with ASCUS, 64.14% for those with CIN, 83.76% for those with cervical cancer in situ, and 83.12% for those with invasive cervical cancer. The most common HPV genotype was HPV-16, followed by HPV-58, HPV-52, HPV-33, HPV-53...
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PMID: 20138618
PDF is available here.
Abstract
The major factors affecting outcome were degree of adhesion (OR, 1.91; P=0.03) in the former group and parity (OR, 0.55; P=0.005) and depth of intramural penetration of the myoma (OR, 30.74; P<0.001) in the latter. Severe intrauterine adhesion, low parity, and deep intramural penetration of submucos...
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PMID: 20096833
PDF is available here.
Abstract
OBJECTIVE: To investigate the effects of testosterone and metformin on glucose metabolism in endometrium. DESIGN: In vitro experiment. SETTING: Reproductive and Genetic Center, Obstetrics and Gynecology, The First Hospital of Peking University, Beijing, China. PATIENT(S): Premenopausal women undergo...
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PMID: 19328476
PDF is available here.
Abstract
Improvements in HRQOL after treatment with mifepristone are partly explained by improvements in pain and bleeding, but not uterine size. However, most of the improvement in HRQOL is not explained by improvements in these clinical parameters.
Copyright International Federation of Gynecology and Obste...
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PMID: 20132932
PDF is available here.
Abstract
A 53-year-old woman with choriocarcinoma (high-risk gestational trophoblastic disease: FIGO score 17) was treated with paclitaxel (175 mg/m(2)) and carboplatin (AUC=5). The patient was treated with an EMA/CO regimen as initial chemotherapy, but she developed EMA/CO-induced interstitial lung disease...
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PMID: 20495335
PDF is available here.
Abstract
We have analysed 297 observations gathered in litterature from 1904 to 2004. The increase in the number of Meigs pseudosyndromes based on diverse associated condition means that we must include under the name Demons syndrome, as he did himself, all tumours of the female genital tract, providing they...
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PMID: 20117886
PDF is available here.