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Neoplasms, Second Primary (0):
Recent article
Neoplasms, Second Primary
Abstract
Survivors of childhood cancer are at excess risk of developing subsequent primary neoplasms but the long-term risks are uncertain.
To investigate long-term risks of subsequent primary neoplasms in survivors of childhood cancer, to identify the types that contribute mo...
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PMID: 21642683
PDF is available here.
PDF is available here.
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The Breast (20)2 2011
Abstract
Our results confirm international findings indicating worse outcomes from bilateral compared with unilateral breast cancer.
Copyright © 2010 Elsevier Ltd. All rights reserved....
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PMID: 21093260
PDF is available here.
PDF is available here.
Abstract
Signet ring cell carcinoma of the ampulla of Vater is a rare entity and less than 20 cases have been described in the literature. We report the cases of two patients with this disease and provide a literature review of previous studies.
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PMID: 21376425
PDF is available here.
PDF is available here.
Abstract
Women with a personal history of breast cancer (PHBC) are at risk of developing another breast cancer and are recommended for screening mammography. Few high-quality data exist on screening performance in PHBC women.
To examine the accuracy and outcomes of mammography...
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PMID: 21343578
PDF is available here.
PDF is available here.
Abstract
We recommend delayed autologous reconstruction after completion of radiotherapy....
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PMID: 20697311
PDF is available here.
PDF is available here.
Abstract
The increasing incidence of radiation-induced sarcoma (RIS) has become a significant problem that can limit long-term survival. The objective of the current study was to analyze the clinicopathologic characteristics, treatment outcomes, and prognostic factors of RIS after radiotherap...
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PMID: 20715161
PDF is available here.
PDF is available here.
Abstract
A 75-year-old female patient underwent distal gastrectomy with lymph node dissection for gastric cancer. Six months later, computed tomography (CT) and magnetic resonance imaging (MRI) revealed liver metastasis and radio frequency ablation (RFA) was performed. Ten months later, she underwent a parti...
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PMID: 21066856
PDF is available here.
PDF is available here.
Abstract
A subset of patients with recurrent or second intraoral tumors undergo both primary and secondary mandibular reconstruction using bilateral fibula flaps. The objective of this report is to describe indications and outcomes for these patients.
A retrospective analysis of a prospectively collected dat...
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PMID: 21042111
PDF is available here.
PDF is available here.
Journal of Neurosurgery (113)5 2010
Abstract
The study of patients with multiple neoplasms can yield valuable insight into the common pathogenesis of both diseases, as well as identify more subtle risk factors that might not be as readily apparent otherwise. The authors present an analysis of the prevalence of previously diagnosed extracranial...
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PMID: 20433279
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We report a case of primary squamous cell carcinoma of the salpinx (PSCCS) with immunohistochemical and molecular studies to evaluate the phenotype and define the etiopathogenesis of this neoplasm. A 77-year-old woman, 38 years postmenopausal, was admitted to the Department of Obstetrics and Gynecol...
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PMID: 20881860
PDF is available here.
PDF is available here.
Acta Oncologica (49)8 2010
Abstract
We analysed the incidence of second primary intracranial tumours in patients with pituitary adenomas treated with radiotherapy compared to the risk of patients not exposed to irradiation and to the general population.
This retrospective cohort study includes 298 patients with pituitary adenomas that...
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PMID: 20429723
PDF is available here.
PDF is available here.
British Journal of Cancer (103)9 2010
Abstract
We report on the descriptive epidemiology of scrotal cancer in the Netherlands.
Data on all scrotal cancer patients were obtained from the Netherlands Cancer Registry (NCR) in the period 1989-2006 and age-standardised incidence rates were calculated also according to histology and stage. Relative su...
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PMID: 20877361
PDF is available here.
PDF is available here.
Abstract
We report a young girl presenting with metachronous multicentric recurrent benign GCT, with the lesions involving the ipsilateral right hand and distal humerus. She was successfully treated with an aggressive surgical approach (en-bloc resection)....
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PMID: 21138229
PDF is available here.
PDF is available here.
Abstract
We must follow up on patients undergone resection of lung cancer at the long-term periods. Recent amelioration of chemotherapy and radiotherapy can keep patients with recurrent lung cancer survive by over 5 years. It is important not only to perform an aggressive 2nd operation for recurrent lung can...
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PMID: 20954345
PDF is available here.
PDF is available here.
Abstract
We retrospectively reviewed 62 patients who underwent surgical treatment for postoperative recurrent or 2nd primary lung cancer. Of the 62 patients, 43 were men and 19 were women with an average age of 67.6 years old. The histology of the initial primary lung cancer was adenocarcinoma in 42 patients...
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PMID: 20954346
PDF is available here.
PDF is available here.
Abstract
We conclude that an aggressive surgical approach for a 2nd primary lung cancer is effective and is linked with good outcome if the tumor is detected at stage IA, when the possible cure by performing wedge resection is promissing....
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PMID: 20954347
PDF is available here.
PDF is available here.
Abstract
We analyzed 39 patients who underwent a 2nd resection for recurrent (solitary pulmonary metastasis) or 2nd primary lung cancer. Based on the pathological findings, 18 patients were diagnosed as recurrent lung cancer, and 21 patients were diagnosed as 2nd primary lung cancer. Overall 5-year survival...
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PMID: 20954348
PDF is available here.
PDF is available here.
Abstract
During a 24-year period (1986-2009), 74 patients (3.5%) underwent iterative surgical resections for 2nd primary and recurrent lung cancer. Patients are classified to 5 groups: 20 2nd primary lung cancer patients undergoing lobectomy (A), 24 2nd primary lung cancer patients undergoing limited resecti...
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PMID: 20954351
PDF is available here.
PDF is available here.
Abstract
Among 659 resected lung cancer cases from 1994 to 2009, 57 secondary lung cancers (8.6%) were evaluated. The secondary tumors were synchronous, located in the same lobe in 10, the ipsilateral different lobe in 17, and the contralateral lobe in 13, or metachronous, located in the contralateral lobe i...
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PMID: 20954350
PDF is available here.
PDF is available here.
Abstract
We performed a retrospective review of 45 consecutive patients with metachronous multiple primary lung cancer who underwent resection between 1990 and 2009. Surgical treatment of the 1st tumor consisted of 39 lobectomies and 3 segmentectomies, and 3 wedge resections. The 2nd tumor was removed by mea...
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PMID: 20954349
PDF is available here.
PDF is available here.
Abstract
We considered 42 cases (3 of completion pneumonectomy and 39 of VATS) to be metachronous lung cancer and 8 cases of VATS to be recurrence by detailed histologic assessment. We examined 39 cases of metachronous lung cancer resected by VATS. The patients were aged 68 +/- 8 years and 4 patients were ag...
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PMID: 20954352
PDF is available here.
PDF is available here.
Annals of Internal Medicine (153)7 2010
Abstract
Annals of Internal Medicine (153)7 2010
Abstract
In average-risk female survivors, 2743 of 3392 (80.9%) reported having a Papanicolaou smear within the recommended period, and 140 of 209 (67.0%) reported mammography within the recommended period. In high-risk survivors, rates of recommended mammography among women were only 241 of 522 (46.2%) and...
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PMID: 20921543
PDF is available here.
PDF is available here.
Minnesota medicine (93)10 2010
Abstract
Hematopoietic stem-cell transplantation is a potentially curative therapy for many high-risk hematologic malignancies and other life-threatening disorders. Advances in transplantation over the last four decades have resulted in an increasing number of long-term survivors who may be at risk for devel...
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PMID: 21140762
PDF is available here.
PDF is available here.
Minnesota medicine (93)10 2010
Abstract
Children who are diagnosed with cancer have a five-year survival rate of nearly 80%, and many live well into adulthood. Because of their disease and treatment exposures, survivors of childhood cancer are at risk for unique long-term health effects. This article reviews some of the more common late e...
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PMID: 21140760
PDF is available here.
PDF is available here.
Abstract
A high risk of new mucosal malignancies of the upper aerodigestive tract (UADT) is seen in patients successfully treated for oral cancer. The prognosis is unclear for these patients. A typical failure may be located at the site of the first tumor i.e. a local recurrence; or separately as a second pr...
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PMID: 20618618
PDF is available here.
PDF is available here.
Abstract
We report a case of primary Epstein Barr virus (EBV) negative peripheral T-cell lymphoma (PTCL) NOS in a 56-year-old female who-after an initially indolent course - simultaneously developed an aggressive, EBV+ cytotoxic large T-cell lymphoma, clonally related to the primary PTCL, and an EBV+, clonal...
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PMID: 20739840
PDF is available here.
PDF is available here.
Annals of Surgery (252)3 2010
Abstract
Amsterdam patients undergoing partial colectomy have a high rate of metachronous high-risk adenomas and carcinomas. Total colectomy for the index cancer is the procedure of choice. For either surgical option, yearly endoscopic surveillance is essential to remove premalignant adenomas....
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PMID: 20739851
PDF is available here.
PDF is available here.
Endocrine Pathology (21)3 2010
Abstract
We describe, a 74-year-old woman, presented with a 2 months' history of lower abdominal pain and episodic intestinal subocclusion due to a complex pelvic mass. The mass consisted predominantly of a Brenner tumor associated with struma ovarii containing a single small island of thyroid tissue that ha...
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PMID: 20532676
PDF is available here.
PDF is available here.
Endocrine Pathology (21)3 2010
Abstract
We describe the first case of a carcinoid composed of ghrelin-producing cells arising in a tailgut cyst. Ghrelin production was demonstrated using immunohistochemistry, electron microscopy, and reverse transcription-polymerase chain reaction methods. A 73-year-old woman with back and pelvic pain was...
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PMID: 20532674
PDF is available here.
PDF is available here.
Abstract
We retrospectively analyzed data from 108 craniopharyngioma, medulloblastoma, and ependymoma patients. Risk factors were identified using multifactorial univariate regression analysis. Recurrences occurred in 41 and second malignant neoplasms in 4 patients. There were significant correlations for co...
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PMID: 21175094
PDF is available here.
PDF is available here.
Abstract
We want to emphasize that after treatment is of vital importance. Besides the main focus of oncology on the early detection of recurrent tumours, distant metastases and second primary tumours as well as a fast interdisciplinary and mostly multimodal treatment planning, consultation is also a central...
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PMID: 20694544
PDF is available here.
PDF is available here.
Abstract
Recurrent disease is one of the main reasons for the persistently poor prognosis of squamous cell carcinoma of the head and neck (HNSCC; European 5-year survival, 42%). The main treatment option for primary and secondary malignancy as well as recurrent disease is surgical therapy. If R0 resection (r...
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PMID: 20628714
PDF is available here.
PDF is available here.
Abstract
We present the cases of two breast cancer patients who developed filiae into the petrous portion of the temporal bone and one very rare case of metastasis to the larynx. Diagnosis, therapy and distinctive features of metastasis to the head and neck region are discussed.Secondary to long-term endocri...
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PMID: 20596682
PDF is available here.
PDF is available here.
Abstract
Adding concurrent-adjuvant chemotherapy statistically significantly reduced failure and cancer-specific deaths when compared with radiotherapy alone. Although there was no statistically significant increase in major late toxicity, increase in noncancer deaths narrowed the resultant gain in overall s...
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PMID: 20634482
PDF is available here.
PDF is available here.
Connecticut medicine (74)7 2010
Intrathoracic lymphadenopathy: sarcoidosis or metastatic seminoma? The diagnostic dilemma revisited.
Abstract
We report a young patient with stage I testicular seminoma followed by close surveillance after radical orchidectomy, who developed hilar and subcarinal lymphadenopathy more than two years after the original diagnosis. A mediastinal biopsy was consistent with noncaseating granuloma with no evidence...
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PMID: 20806619
PDF is available here.
PDF is available here.
Bulletin du cancer (97)8 2010
Abstract
The treatment of acute leukemia is usually similar in women and men. The outcome is also generally the same. However, diagnosis in women poses additional challenges in clinical practice such as leukemia following breast or ovarian cancers, prevention of abnormal uterine bleeding in premenopausal fem...
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PMID: 20435579
PDF is available here.
PDF is available here.
Abstract
We suspected pneumonia. After clarithromycin (CAM) was administered for three months, CT scanning demonstrated in July 2008 that the nodule was enlarged more than the CT scanning of 2006. We had performed bronchoscopy on April 2009, and obtained a specimen for the nodule. We diagnosed adenocarcinoma...
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PMID: 20716884
PDF is available here.
PDF is available here.
Abstract
We retrospectively analyzed the follow-up results of 338 patients with newly detected lesions. Twenty-one patients were finally diagnosed with second primary malignancies. In addition, the second primary malignancies of 17 patients were diagnosed at an early stage (P = 0.007). Thirteen patients were...
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PMID: 20091320
PDF is available here.
PDF is available here.
Abstract
As childhood cancer survivors progress through adulthood, risk of subsequent neoplasms increases. Patients surviving Hodgkin lymphoma are at greatest risk. There is no evidence of risk reduction with increasing duration of follow-up....
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PMID: 20634481
PDF is available here.
PDF is available here.
Abstract
Local tumor control was shown to be high using SBRT for non-small-cell lung cancer. Overall survival is highly coerrelated with the development of distant metastasis.
Copyright 2010 Elsevier Inc. All rights reserved....
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PMID: 19800181
PDF is available here.
PDF is available here.
Abstract
We report a 64-year-old patient who complained of right testicular pain. Right-sided orchiectomy was performed, and metastatic signet ring cell carcinoma of spermatic cord and testis was diagnosed through histological examination and immunohistochemistry. The following stomach biopsy confirmed the p...
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PMID: 20399569
PDF is available here.
PDF is available here.
Abstract
We present the case of a 49-year-old woman with a past medical history of invasive ductal breast carcinoma 13 years ago, and who was recently diagnosed as having a low-grade adenosquamous carcinoma in the same breast. Genetic analysis of blood DNA revealed a BRCA1 mutation. To our knowledge, BRCA1 m...
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PMID: 20189727
PDF is available here.
PDF is available here.
Abstract
We studied the natural history of SSA by analyzing the outcome of previously undiagnosed SSAs and comparing it with that of hyperplastic polyps (HPs) and APs. All colorectal polyps diagnosed between 1980 and 2001 as HP were selected for study. Polyps identified as possible SSAs were reviewed by 3 pa...
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PMID: 20551824
PDF is available here.
PDF is available here.
Abstract
We report on a case of unilateral absence of a pulmonary artery that was complicated by contralateral primary lung cancer. We performed a right middle lobectomy despite the absence of the left pulmonary artery and detected changes in respiratory function during the operation. The present case provid...
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PMID: 20609736
PDF is available here.
PDF is available here.
Abstract
Our results suggest that in addition to high Ki-67 proliferation index, high E2F1 expression may also be a useful predictive marker for malignant potential of GISTs....
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PMID: 20571341
PDF is available here.
PDF is available here.
Abstract
We carried out a systematic review to determine the association between NMSC and subsequent risk of other cancers.
Bibliographic databases were searched through March 2009. Studies were included if sufficient information was presented to estimate the risk of developing other cancers...
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PMID: 20570907
PDF is available here.
PDF is available here.
Abstract
Medical Oncology (27)2 2010
Abstract
Although breast cancer is the most common disease for women, bilateral breast cancer is a rare situation. Development of a second malignancy which is the most frightening side effect, may be related with genetic predisposition or cancer treatment. Because our case is a survivor of acute lymphoblasti...
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PMID: 19472087
PDF is available here.
PDF is available here.
Abstract
We described here a patient who had two lung masses. Although the two masses had the same histology and a similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lung...
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PMID: 20526397
PDF is available here.
PDF is available here.
Cancer/Radiothérapie (14)3 2010
Abstract
The median age was 16 years. Sixty-three percent of patients had undifferentiated tumors. Sixty-six percent had locally advanced tumor. With a median follow-up of 107 months, one patient presented a local relapse, 24 patients developed distant metastases with a median delay of 7 months. The 5 years...
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PMID: 20347607
PDF is available here.
PDF is available here.
Melanoma Research (20)3 2010
Abstract
We sought to determine the types of NMMs that occur in melanoma patients, to document the frequency with which they were diagnosed by FNB, and to highlight potential pitfalls in cytologic diagnosis. NMMs occurring in 1416 consecutive melanoma patients who underwent FNB of 2204 clinically suspicious...
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PMID: 20335819
PDF is available here.
PDF is available here.
Abstract
We describe here the case of a 68-year-old woman who developed synchronous cutaneous angiosarcoma, melanoma and morphea of the breast skin and the local area, 14 years after radiotherapy for breast carcinoma. Given the risk of post-radiation secondary primaries in breast cancer patients, long-term s...
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PMID: 20526547
PDF is available here.
PDF is available here.
Abstract
It is mandatory that survivors of cancer should be monitored carefully, so that the complications related to their previous disease and therapy are detected early and managed properly....
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PMID: 19922704
PDF is available here.
PDF is available here.
Medical Physics (37)5 2010
Abstract
The treatment-related second cancer risks in organs outside the primary beam due to 3D-CRT and IMRT is small. New risk assessment techniques need to be investigated to address the concern of radiation-induced second cancers from prostate treatments, particularly focusing on risks to organs inside th...
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PMID: 20527532
PDF is available here.
PDF is available here.
Modern Pathology (23)5 2010
Abstract
We investigated differential expressions of TTF-1, Napsin A, surfactant apoprotein A, estrogen receptor, GATA-3, mammaglobin, and GCDFP-15 immunostains in 197 pulmonary carcinomas (158 adenocarcinomas, 39 squamous) and 115 invasive mammary carcinomas (91 ductal, 24 lobular type). In mammary carcinom...
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PMID: 20173733
PDF is available here.
PDF is available here.
Abstract
Li-Fraumeni syndrome (LFS) is one of the familial cancers characterized by different tumors and hereditary TP53 mutations. The adrenocortical carcinoma (ACC) association with acute leukemia is unusual in childhood, even in LFS. The authors here present a family with pR337P mutation in TP53 gene who...
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PMID: 20426520
PDF is available here.
PDF is available here.