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Brain Infarction (2):
Recent article
Brain Infarction
Abstract
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Acta Neurologica Belgica (110)3 2010
Abstract
Cerebrovascular Diseases (30)3 2010
Abstract
CADASIL is responsible for diffuse hyperintensities in the white matter on FLAIR images. These lesions are often associated with focal lesions in the basal ganglia such as lacunar infarctions. The prevalence and significance of diffuse or confluent thalamic hyperintensities (CTH) remain unknown.
The...
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PMID: 20664266
PDF is available here.
PDF is available here.
Lancet Neurology (9)7 2010
Abstract
120 patients were randomly assigned to treatment (87 women and 33 men): 61 to lamotrigine and 59 to placebo. 108 patients were analysed for the primary endpoint: 52 in the lamotrigine group and 56 in the placebo group. The mean change in partial (central) cerebral volume per year was -3.18 mL (SD -1...
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PMID: 20621711
PDF is available here.
PDF is available here.
Abstract
Cerebral venous sinus (sinovenous) thrombosis (CSVT) in childhood is a rare, but underrecognized, disorder, typically of multifactorial etiology, with neurologic sequelae apparent in up to 40% of survivors and mortality approaching 10%. There is an expanding spectrum of perinatal brain injury associ...
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PMID: 20561500
PDF is available here.
PDF is available here.
Human Brain Mapping (31)7 2010
Abstract
We used fMRI and acoustically paced movements of the right index finger at six different frequencies to define the role of these regions for recovery after stroke. Eight well-recovered patients with a chronic striatocapsular infarction of the left hemisphere were compared with eight age-matched part...
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PMID: 20091792
PDF is available here.
PDF is available here.
Archives of Neurology (67)7 2010
Abstract
Diagnosis of PPIS is often delayed. The association of acute perinatal risk factors with APPIS compared with PVI supports distinct timing of these diseases. Prospective, case-control risk factor studies of PPIS subtypes are required to develop prevention strategies....
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PMID: 20625091
PDF is available here.
PDF is available here.
Abstract
A narrower central retinal arteriole equivalent, wider central retinal venule equivalent, focal arteriolar narrowing, and arteriovenous nicking were predictive of lacunar stroke. Retinal imaging is useful in understanding the pathophysiology and mechanisms of cerebral small-vessel disease....
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PMID: 20522816
PDF is available here.
PDF is available here.
Abstract
This study suggests that medial pontine lacunes may be due to a penetrating artery disease secondary to basilar artery atherosclerosis. High-resolution MRI could help precise stroke subtyping....
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PMID: 20538696
PDF is available here.
PDF is available here.
Neurological Research (32)5 2010
Abstract
Low density lipoprotein is transcytosed across the blood-brain barrier mediated by low density lipoprotein receptor (LDLR). LDLR in the brain is mainly expressed on capillary endothelial cells and is therefore considered to be an important susceptibility gene in modifying the stroke presentation. A...
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PMID: 19589204
PDF is available here.
PDF is available here.
Neurological Research (32)5 2010
Abstract
TMP protected brain from damage by reducing volume of infarction, neuronal loss and water content. TMP not only increased the number of BrdU positive cell in SVZ, but also stimulated the cell differentiation after ischemia. The nNOS expression in cortex and dentate gyrus was reduced by treatment of...
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PMID: 20501058
PDF is available here.
PDF is available here.
Lack of the Toll-Like Receptor 4 Gene Polymorphisms Asp299Gly and Thr399ile in a Chinese Population.
Abstract
We speculate they might not be an important factor in the development of CI in the Chinese....
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PMID: 20504212
PDF is available here.
PDF is available here.
Annals of Neurology (67)6 2010
Abstract
Zhonghua Yixue Zazhi (90)21 2010
Abstract
To analyze the correlative factors of traumatic embolism in superficial cerebral vein and explore their corresponding treatments.
A total of 74 cases were divided into 3 groups according to their injury mechanisms. Group A: traumatic brain injury in superficial cerebral vein with cerebral contusion,...
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PMID: 20973225
PDF is available here.
PDF is available here.
Abstract
We describe a patient who presented with unilateral paresthesia after acute isolated infarct of the splenium. CASE REPORT: A 74-year-old woman presented with acute onset of right sided numbness and tingling. MR imaging of the brain showed hypointensity on T1-weighted images and on apparent diffusion...
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PMID: 20714962
PDF is available here.
PDF is available here.
Abstract
Our study is the first systematic study of perinatal stroke in Korea, and shows its clinical presentations and neurodevelopmental outcomes. The population-based study on incidence and prognosis of perinatal stroke in Korea is required in the future....
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PMID: 20514310
PDF is available here.
PDF is available here.
Neuroscience Letters (475)3 2010
Abstract
We examined whether these pathological changes, especially temporal occurrence, were present in patients who suffered from cerebral ischemia. The studies by immunohistochemistry show that ER chaperone glucose-regulated protein (GRP78) and caspase-9 elevate around infarction areas. The experiments by...
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PMID: 20347937
PDF is available here.
PDF is available here.
Abstract
Brain research (1330) 2010
Abstract
We measured and compared infarction volumes to investigate the effect of GGA on cerebral infarction induced by permanent middle cerebral artery occlusion in rats. We evaluated the effects of pretreatment with 5-hydroxydecanoate (5HD), a specific mitochondrial ATP-sensitive potassium (mitoK(ATP)) cha...
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PMID: 20206146
PDF is available here.
PDF is available here.
Neurosurgery (66)5 2010
Abstract
We present a comprehensive review of intracranial aneurysms in Klippel-Trenaunay and Klippel-Trenaunay-Weber syndromes (KTS/KTWS), and examine factors influencing the risks of surgery vs conservative management. CLINICAL PRESENTATION: A 58-year-old physician with KTS affecting the right extremities...
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PMID: 20404675
PDF is available here.
PDF is available here.
Abstract
We aimed to determine the prevalence and severity of cerebrovascular pathologies in DLB and PD and to analyze their relationship to LB pathology. The prevalence and severity of atherosclerosis in the circle of Willis, cerebral amyloid angiopathy, cerebral infarcts, hemorrhages, small-vessel disease,...
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PMID: 20418782
PDF is available here.
PDF is available here.
Abstract
We investigated polymorphisms in the endothelial nitric oxide synthase (eNOS) gene (i.e., -786T>C, 4a4b and 894G>T) as possible risk factors for SBI. We enrolled 269 patients with SBI and 234 control subjects and examined their fasting plasma homocysteine and folate levels, and analyzed for eNOS pol...
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PMID: 20372828
PDF is available here.
PDF is available here.
Abstract
Leptin can be the stroke manifestation of obesity. There is necessary to further evaluation of leptin's role in the pathogenesis of cerebrovascular diseases and its potential role in prophylaxis of ischemic stroke....
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PMID: 20568400
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (103)5 2010
Abstract
We determined the prevalence of microthrombosis in the brain in an asymptomatic subgroup of patients with b-thalassaemia intermedia (TI) who had undergone splenectomy. This retrospective review included 200 patients with TI diagnosed on the basis of blood count, haemoglobin (Hb) electrophoresis and...
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PMID: 20174764
PDF is available here.
PDF is available here.
Behavioural Brain Research (209)1 2010
Abstract
Recent studies indicate that progesterone (PROG) protects against animal brain injury, including ischemic stroke, in various animal models. However, there are insufficient studies about PROG in other various groups such as ovariectomized females and aged animals. This study was designed to examine t...
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PMID: 20109497
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)15 2010
Abstract
We used the rat photothrombosis model of cortical stroke. Using in vitro patch-clamp recordings at various times after the photothrombotic injury, we show that localized strokes in the somatosensory cortex induce long-term reductions in intrinsic excitability and evoked synaptic excitation of nRT ce...
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PMID: 20392967
PDF is available here.
PDF is available here.
Abstract
We can detect masked hypertension. I present two interesting cases of possible masked hypertension in this commentary....
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PMID: 20404601
PDF is available here.
PDF is available here.
Abstract
The quality-adjusted life expectancy for a patient with ischemic stroke was 8.7 quality-adjusted life-years with an average loss of 8.3 quality-adjusted life-years, and there appeared to be no difference between lacunar and nonlacunar infarctions. Patients with intracerebral hemorrhage had a similar...
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PMID: 20150543
PDF is available here.
PDF is available here.
Abstract
Patients with deep ICH and lacunar infarcts are more likely than patients with nonlacunar infarcts to have signs indicating hypertensive damage in the retinal arteriolar wall....
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PMID: 20167920
PDF is available here.
PDF is available here.
Abstract
Hypertension and diabetes appear equally common in lacunar and nonlacunar ischemic stroke, but lacunar stroke is less likely to be caused by embolism from the heart or proximal arteries, and the lower prevalence of ischemic heart disease in lacunar stroke provides additional support for a nonatheros...
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PMID: 20150553
PDF is available here.
PDF is available here.
Yonsei Medical Journal (51)2 2010
Abstract
The plasma tHcy levels were significantly higher in patients with SBI than in healthy controls. Despite a significant association between the MTHFR 677TT genotype and hyperhomocysteinemia, the MTHFR 677C>T genotypes did not appear to influence susceptibility to SBI. However, odds ratios of the 1298A...
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PMID: 20191019
PDF is available here.
PDF is available here.
Abstract
We review the available evidence linking hyperglycemia to a poor clinical outcome in patients with ischemic stroke. We highlight the pathophysiological mechanisms that might underlie the deleterious effects of hyperglycemia on acute stroke prognosis and systematically review the literature concernin...
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PMID: 20157308
PDF is available here.
PDF is available here.
Abstract
(1) Acupoint groups could obviously reduce the brain infarction area in MCAO rats. Under 9 intervention parameters, acupoint groups had much more effectiveness tendency than that of the non-acupoint groups. (2) Acupoint group VI was the most effective in reducing the brain infarction area among 9 ac...
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PMID: 20496739
PDF is available here.
PDF is available here.
Neurologist (16)2 2010
Abstract
We report a patient with bilateral superior altitudinal hemianopia. CASE REPORT: A 40-year-old man developed bilateral superior altitudinal hemianopia secondary to bilateral parahippocampal and fusiform gyrus lesions. Vision loss was acute, and onset bilateral and simultaneous. Complete neuro-ophtha...
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PMID: 20220453
PDF is available here.
PDF is available here.
Neurologist (16)2 2010
Abstract
The patient was found to have an acute brain infarct in a watershed distribution secondary to multiple, bilateral, intraparenchymal air bubbles. Further investigation revealed a large lung bulla with an air-fluid level. CONCLUSION: Air embolism was due to rupture of the lung bulla into the pulmonary...
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PMID: 20220454
PDF is available here.
PDF is available here.
Abstract
Although prevalent in patients with vascular risk factors and stroke, enlarged perivascular spaces are specifically associated with lacunar ischemic stroke and white matter hyperintensities. Further studies should determine the mechanism of this association while including adequate controls to accou...
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PMID: 20056930
PDF is available here.
PDF is available here.
Ugeskrift for laeger (172)6 2010
Abstract
This case report highlights laryngeal trauma and stresses the importance of this type of trauma in the emergency room setting. This case report describes an 18-year-old girl who receives a trauma to the larynx and subsequently dies of an infarction of the cerebellum.
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PMID: 20146914
PDF is available here.
PDF is available here.
Connecticut medicine (74)2 2010
Abstract
Behavioral Neuroscience (124)1 2010
Abstract
We tested whether the maladaptive effects of experience with the nonparetic limb are mediated through callosal connections and the contralesional sensorimotor cortex. Adult male rats with proficiency in skilled reaching with their dominant (for reaching) forelimb received ischemic bilateral sensorim...
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PMID: 20141287
PDF is available here.
PDF is available here.
Neurological Sciences (31)1 2010
Abstract
We present a case of pure left insular cortex infarction with isolated truncal ataxia and demonstrate a crucial relationship between the left insular cortex and the cerebellar system. The possible connections are through the spinocerebellar and dentatorubrothalamic pathway. In conclusions, left insu...
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PMID: 19806312
PDF is available here.
PDF is available here.
Neurological Sciences (31)1 2010
Abstract
We present a case of pure left insular cortex infarction with isolated truncal ataxia and demonstrate a crucial relationship between the left insular cortex and the cerebellar system. The possible connections are through the spinocerebellar and dentatorubrothalamic pathway. In conclusions, left insu...
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PMID: 19806312
PDF is available here.
PDF is available here.
Neurological Sciences (31)1 2010
Abstract
We present a case of pure left insular cortex infarction with isolated truncal ataxia and demonstrate a crucial relationship between the left insular cortex and the cerebellar system. The possible connections are through the spinocerebellar and dentatorubrothalamic pathway. In conclusions, left insu...
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PMID: 19806312
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)4 2010
Abstract
We demonstrate a role for D-serine in NMDA receptor-mediated neurotoxicity and stroke. Brain cultures of SR-deleted mice display markedly diminished nitric oxide (NO) formation and neurotoxicity. In intact SR knock-out mice, NO formation and nitrosylation of NO targets are substantially reduced. Inf...
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PMID: 20107067
PDF is available here.
PDF is available here.
Annals of Neurology (68)1 2010
Abstract
We conducted a retrospective analysis of the surgical outcome of 410 pediatric MMD patients. All patients were treated in a relatively uniform scheme at a single institution. The surgical procedures consisted of bilateral encephaloduroarteriosynangiosis augmented by bifrontal encephalogaleo-/periost...
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PMID: 20582955
PDF is available here.
PDF is available here.
Abstract
It is known that the level of protein-conjugated acrolein in plasma is a good marker of chronic renal failure and brain infarction. Thus, studies were carried out to determine which kinds of plasma proteins are conjugated with acrolein. It was found that acrolein was mainly conjugated with albumin....
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PMID: 20006585
PDF is available here.
PDF is available here.
Abstract
We evaluated the efficacy of epigallocatechin gallate (EGCG) for improving function in rats with transient middle cerebral artery occlusion (MCAO). Three procedures underwent for each groups; MCAO and EGCG treatment, MCAO without treatment (MCAO control), and sham operation. Function was evaluated o...
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PMID: 20407485
PDF is available here.
PDF is available here.
Abstract
Abstract
Analysis of published data indicates that erythropoietin plays an important role in regulation of brain tolerance to impact of ischemia-reperfusion. This cytokine is involved in ischemic preconditioning of the brain and can mimic the phenomenon of preconditioning and postconditioning. However, it is...
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PMID: 20297690
PDF is available here.
PDF is available here.
Gaceta medica de Mexico (146)1 2010
Abstract
Cerebrovascular disease is a frequent cause of disability and even death in young patients, and thus its medical approach should be emphasized....
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PMID: 20422936
PDF is available here.
PDF is available here.
European Neurology (63)2 2010
Abstract
No marked differences in total score were evident between the Tr and Op patients. However, the Tr patient showed greater difficulty with dative sentences than the Op patients. Conversely, the Tr patient showed rather high scores with relative sentences, whereas the Op patients were rarely able to ma...
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PMID: 20090341
PDF is available here.
PDF is available here.
European Neurology (63)1 2010
Abstract
The assessment of hypoxic tissue volume after stroke may be useful in predicting patient recovery.
Copyright 2009 S. Karger AG, Basel....
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PMID: 20029217
PDF is available here.
PDF is available here.
European Neurology (64)1 2010
Abstract
The fMRI results showed that primarily the contralateral SM1 was activated during affected hand movements. Therefore, it appears that the motor function of the affected hand, in patients with a pontine infarct, recovers mainly via the lateral corticospinal tract.
2010 S. Karger AG, Basel....
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PMID: 20558983
PDF is available here.
PDF is available here.
European Neurology (64)1 2010
Abstract
The results suggest that MMs, poor motor function, and the activations of ipsilateral motor cortex and both SMAs are closely interconnected in patients with CR infarct.
2010 S. Karger AG, Basel....
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PMID: 20571275
PDF is available here.
PDF is available here.
European Neurology (63)4 2010
Abstract
Neurological deterioration occurred in 16 (31%) of 51 patients. BAD was found in 13 (81%) of 16 patients of the D group and 14 (40%) of 35 in the ND group (p = 0.008). The BA/ICA ratio was 0.73 (0.59-0.84) in the D group and 0.64 (0.55-0.71) in the ND group (p = 0.049). Multivariate regression analy...
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PMID: 20224279
PDF is available here.
PDF is available here.
European Neurology (63)6 2010
Abstract
10-Hz rTMS induces significant bilateral hemodynamic changes in patients with acute ischemic stroke, which appear to be less prominent and less synchronous in patients with cortical infarcts. These findings may allow optimization of the use of TMS in acute stroke.
Copyright 2010 S. Karger AG, Basel...
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PMID: 20516695
PDF is available here.
PDF is available here.
European Neurology (63)6 2010
Abstract
This study suggests that LL patterns of small deep infarcts may result in a higher rate of neurological decline and ipsilateral MCA stenosis than IL patterns.
Copyright 2010 S. Karger AG, Basel....
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PMID: 20516696
PDF is available here.
PDF is available here.
Early decompressive hemicraniectomy following malignant ischemic stroke: the crucial role of timing.
Abstract
Abstract
Physical exercise has been shown to be beneficial in stroke patients and animal stroke models. However, the exact mechanisms underlying this effect are not yet very clear. The present study investigated whether pre-ischemic treadmill training could induce brain ischemic tolerance (BIT) by inhibiting...
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PMID: 20714296
PDF is available here.
PDF is available here.
BMC Neurology (10) 2010
Abstract
Although lacunar syndromes are highly suggestive of small deep cerebral infarctions, lacunar syndromes not due to lacunar infarcts are found in 16.6% of cases. The presence of sensorimotor stroke, limb weakness and sudden onset in a patient with atrial fibrillation should alert the clinician to the...
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PMID: 20482763
PDF is available here.
PDF is available here.
Abstract
We retrospectively evaluated the incidence of ischemic stroke and the efficacy of anticoagulant therapy in paroxysmal AF patients on rhythm control therapy who were stratified by their CHADS2 score. The subjects were 334 NVAF atients (229 men and 105 women, mean age, 68 +/- 12 years, mean follow-up...
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PMID: 20145347
PDF is available here.
PDF is available here.