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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Stroke (1):
Recent article
Stroke
Abstract
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New England Journal of Medicine (365)13 2011
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New England Journal of Medicine (364)22 2011
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New England Journal of Medicine (364)21 2011
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We stratified 408 participants who had had a stroke 2 months earlier according to the extent of walking impairment--moderate (able to walk 0.4 to <0.8 m per second) or severe (able to walk <0.4 m per second)--and randomly assigned them to one of three training groups. One group received training on...
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PMID: 21612471
PDF is available here.
PDF is available here.
Abstract
Acute ST-segment elevation myocardial infarction (STEMI) is a leading cause of morbidity and mortality. In experimental models of MI, erythropoietin reduces infarct size and improves left ventricular (LV) function.
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PMID: 21558517
PDF is available here.
PDF is available here.
Abstract
Abstract
We sought to evaluate the impact of personalized coronary heart disease and stroke risk communication on patients' knowledge, beliefs, and health behavior....
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PMID: 21473965
PDF is available here.
PDF is available here.
Abstract
We evaluated how body fat percentage, measured by a portable near-infrared interactance (NIR) device predicts cardiovascular (CVD), coronary heart disease (CHD), and ischemic stroke events in a prospective population-based survey. The study population consisted of 2,842 men and 3,196 women, who part...
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PMID: 20966903
PDF is available here.
PDF is available here.
Abstract
Information relating the outcome of percutaneous coronary intervention to diabetes mellitus or hypertension is limited. The study objective was to describe the outcome in patients undergoing percutaneous coronary intervention in relation to diabetes and hypertension.
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PMID: 21396511
PDF is available here.
PDF is available here.
Abstract
Therapeutic angiogenesis is a novel treatment for ischemic stroke, and vascular endothelial growth factor (VEGF) is a key angiogenic and neuroprotective pharmacological candidate for therapy. However, the greatest challenge of preclinical studies is demonstrating that VEGF-based ther...
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PMID: 20874695
PDF is available here.
PDF is available here.
Abstract
Thrombosis and Haemostasis (105)4 2011
Abstract
The CHADS₂ score predicts the risk of ischaemic stroke in patients with non-valvular atrial fibrillation (NVAF). Most components of the CHADS₂ score are also risk factors of atherosclerosis, and clustering of these risk factors is associated with increased risk of cardiovascular disease, includin...
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PMID: 21301786
PDF is available here.
PDF is available here.
Abstract
The best approach to the management of concomitant severe carotid and coronary artery disease remains unanswered. The American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend carotid endarterectomy (CEA) in asymptomatic carotid stenosis of ≥ 80% either prior to or c...
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PMID: 21156674
PDF is available here.
PDF is available here.
Abstract
Approximately one-third of patients with stroke exhibit persistent disability after the initial cerebrovascular episode, with motor impairments accounting for most poststroke disability. Exercise and training have long been used to restore motor function after stroke. Better training...
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PMID: 21243015
PDF is available here.
PDF is available here.
Medicinski pregled (64)3-4 2011
Abstract
All stroke patients admitted to Banjaluka Clinical Centre during one year were evaluated by the standard protocol during the hospitalization and three months after the stroke. It included clinical, functional and neuropsychological examination and neuroimaging. Dementia was diagnosed according to the...
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PMID: 21905591
PDF is available here.
PDF is available here.
Consumer Reports (76)1 2011
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Casopis lekaru ceskych (150)2 2011
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The authors report a case of a 77 years old male patient with mild stenosis of the carotid artery caused by an exulcerated plaque in the carotid bifurcation. The patient presented with recurrent ipsilateral strokes which were treated with intravenous thrombolysis. A brief review of the literature rel...
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PMID: 21560450
PDF is available here.
PDF is available here.
Abstract
Anesthesiology (114)1 2011
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We prospectively assessed chronic statin therapy compared with no statin therapy, with regard to serious outcomes, by propensity score and multivariable methods.
In propensity-adjusted multivariable logistic regression (c-index: 0.83), statins were associated with an almost threefold reduction in th...
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PMID: 21178671
PDF is available here.
PDF is available here.
Anesthesiology (114)1 2011
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Anesthesiology (114)1 2011
Abstract
Arzneimittel-Forschung (61)4 2011
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We conducted a meta-analysis of randomised controlled clinical trials with duration of at least 12 months and the analysis of cardio- and cerebrovascular endpoints in participants aged 75 years and over. MEDLINE, CENTRAL (Cochrane Central Register of Controlled Trials) and the WHO-ISH Collaboration...
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PMID: 21650080
PDF is available here.
PDF is available here.
Abstract
The use of low-dose aspirin for primary prevention of cardiovascular events in patients with diabetes is recommended by existing guidelines, but definitive evidence supporting its efficacy is lacking. The authors undertook a meta-analysis of published trials to determine the effect of low-dose aspir...
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PMID: 21191260
PDF is available here.
PDF is available here.
Abstract
Abstract
The effects of the anterior ankle-foot orthosis on stroke patients' functional walking ability and fall efficacy were significant. Patients who were of younger age or with low walking ability or both were more suitable for using the anterior ankle-foot orthosis....
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PMID: 20975524
PDF is available here.
PDF is available here.
Nurse researcher (18)2 2011
Abstract
Phenomenology is a recognised approach for investigating experiences in health research. Difficulties regarding the approach, however, have been documented with even the definitions and terminology sometimes being unclear. In addition to this, there have been claims that many nurse r...
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PMID: 21319480
PDF is available here.
PDF is available here.
Abstract
We sought to determine whether referring asymptomatic diabetic patients for screening of silent ischemia decreases the risk of cardiovascular events compared with usual care.
DYNAMIT was a prospective, randomized, open, blinded end-point multicenter trial run between 2000 and 2005, w...
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PMID: 21269454
PDF is available here.
PDF is available here.
Abstract
We reanalyze a published network of trials comparing various antiplatelet interventions regarding the incidence of serious vascular events using Bayesian approaches for random effects MTM, and we explore the advantages and drawbacks of various traditional and new forms of quantitative displays and g...
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PMID: 20688472
PDF is available here.
PDF is available here.
Abstract
We hypothesized that the functional KL-VS and the exonic C1818T variants of Klotho gene may be associated with ischemic stroke in Indian population. We enrolled a total of 460 patients with ischemic stroke and 574 age- and gender-matched controls for the study. Genotyping was done by polymerase chai...
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PMID: 21093413
PDF is available here.
PDF is available here.
Medical Care (48)12 2010
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We used IQI software (v3.1) and 2004-2007 Veterans Health Administration (VA) discharge and Vital Status files to derive 4-year facility-level in-hospital and 30-day observed mortality rates and observed/expected ratios (O/Es) for admissions with a principal diagnosis of acute myocardial infarction,...
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PMID: 20978451
PDF is available here.
PDF is available here.
Abstract
Acta clinica Croatica (49)4 2010
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Recent evidence suggests that lower HDL-cholesterol (HDL-C) may worsen the atherosclerotic process by promoting inflammation and progression from subclinical lesion to clinical event. Carotid intima-media thickness (CIMT) is recognized as a marker of early atherosclerosis and used to...
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PMID: 21830454
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to investigate the early and late outcomes of patients undergoing pulmonary embolectomy for acute massive pulmonary embolus.
Twenty-one patients (15 male, 6 female) underwent pulmonary embolectomy at our institution between March 2001 and July 2010. The median age was 55 ye...
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PMID: 21095299
PDF is available here.
PDF is available here.
Abstract
Abstract
Although hypothermic selective cerebral perfusion (SCP) is widely used for cerebral protection during aortic surgery, little is known about the ideal pump-flow management during this procedure. This study explored cerebral hemodynamics and metabolism at two different flow rates.
Fourteen pigs (33 to...
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PMID: 21095348
PDF is available here.
PDF is available here.
Abstract
Primary Stroke Center designation by the Joint Commission distinguishes those healthcare organizations with exemplary stroke prevention and management. However, meeting the Joint Commission's high-level excellence standards is challenging. This article provides nurse leaders with a stroke education...
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PMID: 21084886
PDF is available here.
PDF is available here.
Abstract
Knowledge of the warning signs of stroke may reduce the incidence of having a second stroke by receiving medical intervention in a timely manner. The need for stroke education is paramount to empower stroke patients to recognize the signs and symptoms of an impending stroke. The purpose of this pilo...
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PMID: 21207769
PDF is available here.
PDF is available here.
Abstract
The major purpose of this study was to identify the types and frequency of caregiving problems and associated stress and coping effectiveness. Secondary purposes were (a) to examine changes in problem frequency, stress, and coping effectiveness over time and (b) to identify relationships between pro...
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PMID: 21207768
PDF is available here.
PDF is available here.
Abstract
Abstract
Nature Medicine (16)12 2010
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Nature Medicine (16)12 2010
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We show that cerebral ischemia induces the interaction of nNOS with postsynaptic density protein-95 (PSD-95). Disrupting nNOS-PSD-95 interaction via overexpressing the N-terminal amino acid residues 1-133 of nNOS (nNOS-N(1-133)) prevented glutamate-induced excitotoxicity and cerebral ischemic damage...
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PMID: 21102461
PDF is available here.
PDF is available here.
Abstract
Achieving remission in late-life depressive disorder is difficult; it is far better to prevent depression. In the last ten years there have been a number of clinical studies of the feasibility of prevention.
A limited literature review was undertaken of studies from 2000 specifically concerning the...
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PMID: 20594389
PDF is available here.
PDF is available here.
Abstract
Previous tools for stroke risk assessment have either been developed for specific populations or lack data on non-fatal events or uniform data collection. The purpose of this study was to develop a stepwise model for the estimation of 10 year risk of stroke in nine different countries across Europe....
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PMID: 20947867
PDF is available here.
PDF is available here.
Biotechnology Journal (5)12 2010
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Tissue engineering is increasingly being recognized as a beneficial means for lessening the global disease burden. One strategy of tissue engineering is to replace lost tissues or organs with polymeric scaffolds that contain specialized populations of living cells, with the goal of r...
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PMID: 21154670
PDF is available here.
PDF is available here.
Abstract
We have previously shown that a high cholesterol (HC) diet results in increases in microglia load and levels of the pro-inflammatory cytokine interleukin-6 (IL-6) in the brains of wild type (WT) and apolipoprotein E knockout (ApoE-/-) mice. In the present investigation, we analyzed whether treatment...
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PMID: 20946880
PDF is available here.
PDF is available here.
Abstract
Brain research (1360) 2010
Abstract
Erythropoietin (EPO) is a potent neuroprotective agent that could be developed as a new treatment for stroke. However, the blood-brain barrier (BBB) is intact in the early hours after stroke when neuroprotection is still possible, and EPO does not cross the intact BBB. To enable BBB transport, human...
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PMID: 20833153
PDF is available here.
PDF is available here.
Brain research (1360) 2010
Abstract
Rats subjected to 2h of transient middle cerebral artery occlusion were studied temporally over 1 year by magnetic resonance imaging (MRI) and behavioral testing. Multiparameter MRI measures of T(2), T(1), T(1) in the presence of off-resonance saturation of the bound proton signal (T(1sat)), apparen...
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PMID: 20828544
PDF is available here.
PDF is available here.
Brain research (1360) 2010
Abstract
The inability of axons in central nervous system (CNS) to regenerate after injury is related partly to multiple endogenous axon growth inhibitors including Nogo receptor (NgR). This study tested the hypothesis that silencing NgR expression by adenovirus-mediated RNA interference (RNAi) (AD-NgR) may...
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PMID: 20828545
PDF is available here.
PDF is available here.
Brain research (1359) 2010
Abstract
Treatment strategies in acute ischemic stroke are still limited. Considering numerous translation failures, research is tending to a preferred use of human-like animal models, and a more-complex perspective of tissue salvaging involving endothelial, glial and neuronal components according to the neu...
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PMID: 20732314
PDF is available here.
PDF is available here.
Abstract
We performed a proteomic study of the human brain after ischemic stroke using a 2-dimensional differential gel electrophoresis-based proteomic approach. In brain samples from 6 deceased stroke patients and 3 control subjects, there was an average of 1,442 ± 231 protein spots in the gels. Changes of...
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PMID: 20940630
PDF is available here.
PDF is available here.
Journal of Trauma (69)5 2010
Abstract
We sought to determine whether the "weekend effect" exists for injured patients at our trauma center.
We performed a retrospective cohort study at a Level I trauma center (2006-2008). The relative risks of mortality associated with weekend or night arrival were estimated using unadjusted and adjuste...
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PMID: 21068609
PDF is available here.
PDF is available here.
Abstract
The introduction of intravenous thrombolytic therapy started the new era of reperfusion therapy in ST elevation myocardial infarction. The addition of aspirin almost halved mortality in patients with ST elevation infarction. Primary coronary intervention (PCI) often in combination with stent implant...
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PMID: 21082532
PDF is available here.
PDF is available here.
Abstract
Therapeutic hypothermia (TH) is very effective for the treatment of acute experimental brain injury. In contrast to other neuroprotective methods or pharmacological agents, TH represents the only clinically proven neuroprotective therapy. TH led to a decreased mortality rate and improved functional...
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PMID: 21082528
PDF is available here.
PDF is available here.
Annals of Internal Medicine (153)9 2010
Abstract
Annals of Internal Medicine (153)9 2010
Abstract
Graduated compression stockings are widely used for deep venous thrombosis (DVT) prophylaxis. Although below-knee stockings are used more often than thigh-length stockings, no reliable evidence indicates that they are as effective as thigh-length stockings.
To compare the effectiveness of thigh-leng...
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PMID: 20855784
PDF is available here.
PDF is available here.
The American Journal of Medicine (123)11 2010
The foundation role of beta blockers across the cardiovascular disease spectrum: a year 2009 update.
Abstract
Hypertension is a risk factor for myocardial infarction (MI), stroke, and heart failure and precedes heart failure in 91% of cases. This becomes even more important considering that the number of Americans with hypertension increased from 65 million in 2005 to 72 million in 2007. If blood pressure i...
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PMID: 21035578
PDF is available here.
PDF is available here.