Abstract
The purpose of the present study was to investigate the effect of red ginseng (Panax ginseng) extracts on the visual process in bullfrog's eye. The results obtained indicated that both dark-adapted and light-adapted ERG b-wave peak amplitude was increased with red ginseng treatment. Furthermore, the...
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PMID: 19830653
PDF is available here.
Maleeha Azam,
Rob W J Collin,
Syed Tahir Abbas Shah,
Aftab Ali Shah,
Muhammad Imran Khan,
Alamdar Hussain,
Ahmed Sadeque,
Tim M Strom,
Alberta A H J Thiadens,
Susanne Roosing,
Anneke I den Hollander,
Frans P M Cremers and
Raheel Qamar
Abstract
Genetic analysis of two Pakistani families with retinal disease enabled the establishment of the correct diagnosis of achromatopsia. Two novel mutations were identified in CNGA3 and CNGB3 that are both specifically expressed in cone photoreceptors. Re-evaluation of the clinical status revealed that...
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PMID: 20454696
PDF is available here.
Abstract
The deposits were absent in the surface epithelium and basal cells of the central cornea before and after treatment. We found crystals mainly in the anterior and medium stroma; they had various shapes; were intracellular, rectangular, or fusiform; and showed hyperreflectivity. The posterior stroma s...
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PMID: 19654516
PDF is available here.
Abstract
We establish a genetic model of photophobia by engineering increased sensitivity to CGRP in mice. These transgenic mice (nestin/hRAMP1) display light-aversive behavior that is greatly enhanced by intracerebroventricular injection of CGRP and blocked by coadministration of the CGRP receptor antagonis...
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PMID: 19587287
PDF is available here.
Abstract
An epidemiological approach to the estimation of the disease onset of various subtypes of monogenic retinal degenerations will be useful for detection of disease duration, its prognosis, rehabilitation and the researching of future treatment possibilities....
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PMID: 19277693
PDF is available here.
Abstract
FL-41 lenses provided both subjective and objective benefit to subjects with BEB. Physicians should consider recommending this noninvasive and inexpensive lens tint to patients with BEB. FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references....
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PMID: 19410958
PDF is available here.
Abstract
CASE REPORT: Observational, case report study. A 45-year-old woman complained of bilateral irritation and photophobia since childhood. Slit-lamp examination revealed yellow-whitish deposits involving the deep stroma of the peripheral half of the cornea in both eyes. The evolution was slowly progress...
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PMID: 19466688
PDF is available here.
Abstract
Characteristic signs are loss of visual acuity, photophobia and central scotoma. The diagnosis of cone dystrophy is determined by a full-field electroretinogram (ERG). Fundus and near-infrared autofluorescence as well as optical coherence tomography allow detection of retinal structural abnormalitie...
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PMID: 19190919
PDF is available here.
Abstract
No significant differences were observed between the use of bromfenac (twice daily) and ketorolac (four times daily) with regard to postoperative PRK discomfort and safety when combined with postoperative measures such as cold BSS and a bandage contact lens....
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PMID: 19241773
PDF is available here.
Abstract
Seeing the light is an expression that usually connotes a conceptual grasp of meaning in all its complexity, while the perception of light is not the issue. In this paper, the authors present a patient with an exquisite light sensitivity that disturbs her sleep; she is "seeing the light" in a sympto...
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PMID: 19334647
PDF is available here.
Abstract
Cortical excitability is high in MA. Headache severity affects visual excitability. Increased P1N2 VEP amplitude before the attack suggests a cyclic decreased intracortical inhibition in extrastriate magnocellular pathways in migraine....
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PMID: 19566496
PDF is available here.
Abstract
Subjects with PD indicated that they tolerate and seek light to a significantly lower degree than normal controls.
(c) 2008 Wiley-Liss, Inc....
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PMID: 19035364
PDF is available here.
Abstract
The MP-1 may be a reliable tool to measure macular sensitivity. Among normal healthy subjects, there was a linear decline in light sensitivity with increasing age.
Copyright 2008 S. Karger AG, Basel....
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PMID: 18849636
PDF is available here.
Abstract
We report the spectrum of ocular toxicity following accidental inoculation of latex of Calotropis procera (Sodom apple) in 29 eyes between January 2003 and December 2006. All patients presented with sudden painless dimness of vision with photophobia. Twenty-five (86%) patients had initial visual acu...
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PMID: 19384022
PDF is available here.
Abstract
We focused mainly on those that reported on the ophthalmological manifestations of such tumours. A number of articles were found dealing with isolated ophthalmological manifestations of these tumours, many of them as presenting symptoms. We also found review articles in English. Apart from oculomoto...
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PMID: 19173206
PDF is available here.
Abstract
A 31-year-old woman who presented with photophobia was found to have bilateral corneal and conjunctival crystal deposition. Ocular cystinosis was diagnosed upon observation of typical crystals and lack of systemic involvement. In vivo confocal microscopy confirmed crystal deposition of the corneas a...
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PMID: 19128385
PDF is available here.
Abstract
This review updates understanding and research on blepharospasm, a subtype of focal dystonia. Topics covered include clinical aspects, pathology, pathophysiology, animal models, dry eye, photophobia, epidemiology, genetics, and treatment. Blepharospasm should be differentiated from apraxia of eyelid...
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PMID: 18852443
PDF is available here.
Abstract
PURPOSE: To discuss the diagnostic and therapeutic challenges presented by an adolescent girl with delayed postural headaches and photophobia that occurred three months after an apparently uncomplicated microscopic lumbar discectomy. CLINICAL FEATURES: A previously healthy girl was admitted to our h...
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PMID: 18835968
PDF is available here.
Abstract
We observed the development of central retinitis. All patients were medicated with the same antibiotics and parabulbar depo of Prednisolonacetate. To 50% of these patients, we suggested eye protection with Yellow Medical filters during two months. In the first group with medication we observed bette...
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PMID: 19138005
PDF is available here.
Abstract
The average days recorded with disability for one or more of the three aspects of activities per headache attack was 0.55. Amongst the headache variables, pain intensity, nausea/vomiting, photophobia, type of abortive treatment and the employment status were significantly correlated with disability....
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PMID: 18549394
PDF is available here.
Abstract
We carried out controlled experimental infections on gammarids using parasites from two different populations. We first determined that parasite intensity increased with exposure dose, but found no relationship between infection and host mortality. Repeated measures confirmed that the parasite alter...
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PMID: 18314127
PDF is available here.
Abstract
The prevalence of cervicogenic headache (CEH) is only vaguely known. Furthermore, it is a common belief that in migraine without aura (MwoA), neck symptoms frequently occur and that MwoA and CEH may pathogenetically be intimately related. In the Vågå study, 1838 18-65-year-old citizens (88.6%...
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PMID: 18494988
PDF is available here.
Abstract
We conducted a prospective study in patients attending a referral out-patient clinic over 5 months and those admitted for an intramuscular indomethacin test. Two hundred and six patients were included. In episodic migraine patients, two of 54 (4%) reported unilateral photophobia or phonophobia, or b...
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PMID: 18422722
PDF is available here.
Abstract
Increased VEP P1N2 amplitude was observed within a few days before the attack. Visual cortex excitability seems to be generally increased in MA as compared to MwoA patients and controls. SIGNIFICANCE: Increased excitability of the visual cortex seems to be detectable in the preattack state, supporti...
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PMID: 18308628
PDF is available here.
Abstract
The approach described here presents the first mouse behavioral assay for assessing aversion/avoidance behavior in response to light that appears to be comparable to human photophobia. This approach can be used to test other causes of sustained photophobia in mouse models, as well as to assess the e...
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PMID: 18568886
PDF is available here.
Abstract
These data suggest the need for prospective research exploring the causal mechanisms by which neck pain and coping response influence disability and underscores the importance of multidisciplinary approaches to headache management....
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PMID: 18377378
PDF is available here.
Abstract
Eighty-five consecutive patients with migraine or probable migraine were questioned, 71 females (83.5%) and 14 males (16.5%). There was denial of light and sound sensitivity in 24% of patients with routine questioning and then awareness of sensitivity in 93% with the further questioning. A total of...
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PMID: 17868350
PDF is available here.
Abstract
We describe a patient whose father and sister were also affected with this condition, consistent with an autosomal dominant genetic transmission. Multiple topical and systemic treatments have been unsuccessful in this patient, attesting to the treatment refractoriness typically seen in KFSD....
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PMID: 18280351
PDF is available here.
Abstract
We report a 28 year-old woman with lifelong photophobia, eye pain and painful plantar hyperkeratotic lesions, necessitating use of a wheelchair. A few days after instituting tyrosine lowering therapy, her eye symptoms disappeared and she could walk without pain. Her brother was later diagnosed with...
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PMID: 18364160
PDF is available here.
Abstract
Thirty-two xeroderma pigmentosum patients were examined during this period. Photophobia was found in 66% of cases and 19 of 32 patients (59%) were presenting ocular and periocular malignancies. The mean age of patients was 19 years (four to 40 years). Thirty-three tumours were diagnosed in these 19...
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PMID: 18342089
PDF is available here.
Abstract
We studied timed CHO- or protein-rich (PROT) diet as a putative therapy for SAD. Unmedicated, DSM-IV-diagnosed depressed women with SAD (n=22, 19-63 yrs) in the follicular phase of the menstrual cycle (present in 19) were randomized to nine days of eating approximately 1600 kcal of either CHO before...
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PMID: 18293149
PDF is available here.
Abstract
Among the 1,377 consecutive new patients seen in our clinic during the study, 34 patients wore sunglasses, among whom 7 (20.6%) had organic visual loss. During the study period, 59 patients were diagnosed with NOVL, among whom 27 (45.8%) wore sunglasses. The sensitivity of wearing sunglasses for NOV...
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PMID: 18195266
PDF is available here.
Abstract
Based on the results of performed tests the diagnosis of Alström syndrome was established. This rare congenital autosomal recessive condition is characterized by progressive cone-rod retinal dystrophy associated with obesity, sensorineural deafness, type 2 diabetes, congenital cardiac insufficien...
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PMID: 18655459
PDF is available here.
Abstract
The results indicate slightly reduced light sensitivity and reduced colour discrimination among the exposed subjects compared to the controls. The findings may be due to previous exposure to acrylamide containing grouts among the tunnel workers....
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PMID: 17949818
PDF is available here.
Abstract
We identified clinical variables that significantly predict therapeutic non-response and evaluated the efficacy of eletriptan (20, 40 and 80 mg) and sumatriptan (100 mg) vs. placebo in a subgroup of patients with all predictor variables. First-attack data were pooled from 10 randomized, double-blind...
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PMID: 17941878
PDF is available here.
Abstract
Of 162 patients, 96 patients had binocular photophobia (60.2%). Photophobia was found to be associated with an angle of exodeviation at distance >25 Prism Diopter (Delta) (p = 0.02), and stereoacuity worse than 60 s (p = 0.02). We defined satisfactory surgical outcome as a deviation of <10 Delta. Of...
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PMID: 18091309
PDF is available here.
Abstract
No signs of progression were noted in the 6 bradyopsia patients. Photophobia, impaired movement perception, variable reduced VA that improved with the use of pinholes and ERG abnormalities were typical for the disease....
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PMID: 17826834
PDF is available here.
Abstract
The BSLPD mitigates symptoms and improves quality of life in patients with severe dry eye from cGHvD....
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PMID: 18043175
PDF is available here.
Abstract
Areas of capillary nonperfusion resulting from severe nonproliferative or proliferative diabetic retinopathy show morphologic changes of the retinal structure, which may lead to a loss of sensitivity....
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PMID: 17868632
PDF is available here.
Abstract
Preoperative visual acuity ranged from hand motion to 0.2 (decimal), and postoperative visual acuity ranged from hand motion to 0.4. Fixation on the graft was shown in four patients. Microperimetry proved light increment sensitivity over the graft in five patients. Light increment sensitivity could...
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PMID: 17653551
PDF is available here.
Abstract
We characterized the susceptibility of vaccinia virus aerosols, as a surrogate for smallpox, to UVC light by using a benchtop, one-pass aerosol chamber. We evaluated virus susceptibility to UVC doses ranging from 0.1 to 3.2 J/m(2), three relative humidity (RH) levels (20%, 60%, and 80%), and suspens...
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PMID: 17644645
PDF is available here.
Abstract
Severe alkali injury of the cornea generally has a good prognosis but can lead to permanent damage and persistent complaints of dry eye....
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PMID: 17721304
PDF is available here.
Abstract
Tafluprost eye drops 0.0025% and 0.005% were generally well tolerated and safe. Tafluprost 0.005% reduced IOP more than placebo or latanoprost 0.005%. Therefore, tafluprost looks promising for further investigation....
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PMID: 17803434
PDF is available here.
Vasiliki Kalatzis,
Nicolas Serratrice,
Claire Hippert,
Olivier Payet,
Carl Arndt,
Chantal Cazevieille,
Tangui Maurice,
Christian Hamel,
François Malecaze,
Corinne Antignac,
Agnes Müller and
Eric J Kremer
Abstract
We characterized the ocular anomalies of Ctns-/- mice to determine whether they mimic those of patients. The most dramatic cystine accumulation was seen in the iris, ciliary body, and cornea of Ctns-/- mice. Consistently, Ctns-/- mice had a low intraocular pressure (IOP) and seemed mildly photophobi...
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PMID: 17597652
PDF is available here.
Abstract
Hyoscine skin patches diminish salivation by their anticholinergic action. The aim of reporting this case series is to present the ophthalmic side effects in children, and to highlight the precautions to take. Five children (two males, three females; age range 8-18y) with quadraplegic cerebral palsy...
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PMID: 17518927
PDF is available here.
Abstract
Luminance perimetry was similar in patients and controls. Color perimetry instead revealed an impairment in the perception of red ("quantitative perception index") in migraine patients; this impairment was more pronounced in patients with MA (P < .001) than in those with MO (P < .05) and was related...
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PMID: 17578541
PDF is available here.
Abstract
INTRODUCTION: Vitamin A deficiency occurs in the poor in developing countries and is one of the main causes of blindness by perforative corneal complications. It is a rare pathology in industrialized countries and it is associated with an absorption syndrome. The authors report the first case of hyp...
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PMID: 17646742
PDF is available here.
Abstract
Primary congenital glaucoma generally presents with a classic clinical triad of photophobia, blepharospasm, and epiphora caused by the corneal changes that occur secondary to increased intraocular pressure (IOP). The condition typically presents bilaterally and is rarely hereditary....
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PMID: 17400138
PDF is available here.
Abstract
Primary congenital glaucoma generally presents with a classic clinical triad of photophobia, blepharospasm, and epiphora caused by the corneal changes that occur secondary to increased intraocular pressure (IOP). The condition typically presents bilaterally and is rarely hereditary....
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PMID: 17400138
PDF is available here.
Abstract
In this randomized, double-blind, crossover clinical trial, adult patients treated two migraine attacks: one with almotriptan 12.5 mg and the other with ergotamine 2 mg plus caffeine 200 mg. Treatment with almotriptan was associated with a significantly greater proportion of patients achieving 2-h p...
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PMID: 17355546
PDF is available here.
Abstract
A 42-year-old man presented with a three-day history of progressive bilateral blurred vision, photophobia and headaches. There was no history of trauma. He was emmetropic with visual acuity of 6/60 (pinhole 6/24) in both eyes, no ptosis and full range of eye movements. His pupils were in fixed mydri...
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PMID: 17311576
PDF is available here.
Abstract
We consider as being totally ignored in the Romanian scientific literature and unexpectedly insufficiently treated in the specialized ophthalmologic literature. Known in the specialty literature under the generic name of "Computer vision syndrome", it is defined by the American Optometric Associatio...
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PMID: 18064965
PDF is available here.
Abstract
AMT is an effective alternative for the management of patients with painful bullous eratopathy. Besides pain relief and reduction of ocular inflammation it remains unclear whether this procedure can also be used to improve vision in eyes with visual potential....
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PMID: 17294377
PDF is available here.