Abstract
Chloroquine retinal toxicity can be recognized in a subclincal form by the presence of early changes in macular sensitivity, detected by MP-1....
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PMID: 19165421
PDF is available here.
Abstract
Mean age was 28.7 years and there were more men (53.7%). The most common visual complaints were blurring of vision (51.2%) and central scotoma (34.1%). Most patients recovered best-corrected visual acuity >20/40. Optical coherence tomography showed 3 patterns of maculopathy: 1) diffuse retinal thick...
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PMID: 20094013
PDF is available here.
Abstract
Silicone oil is used as intravitreal tamponading agent in surgery for rhegmatogenous retinal detachment (RRD) cases complicated with proliferative vitreoretinopathy (PVR). Recently, a number of case series have appeared where profound central visual loss has been found in eyes after uncomplicated vi...
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PMID: 20234980
PDF is available here.
Abstract
Scotoma displacement recorded with macular perimetry methods offers reasonable indirect estimates of PRL location....
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PMID: 20130712
PDF is available here.
Abstract
The results indicate that the TMC is a feasible device for detection of VFD....
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PMID: 19882509
PDF is available here.
Abstract
MS is accompanied by visual function alteration even in the absence of acute optic neuropathy. The important correlation between functional and anatomic aspect confirms the value of OCT to appreciate the subclinical involvement of the optic nerve. Associated with tests exploring visual function, the...
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PMID: 19882537
PDF is available here.
Abstract
We report a case of brain infarction in the anterior choroidal artery territory accompanied homonymous scotomas. A 59-year-old man with diabetes mellitus felt weakness in his left upper and lower extremities. He was admitted to our hospital with mild hemiparesis on his left side. He noticed a small...
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PMID: 19697888
PDF is available here.
Abstract
To examine and observe the subtle retinal injuries caused by a titanium:sapphire laser with a high-resolution adaptive optics (AO) fundus camera and with Fourier-domain optical coherence tomography (FD-OCT).
Observational case series.
Four eyes of 2 in...
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PMID: 19327747
PDF is available here.
Abstract
Achromatic perimetry is the gold standard in glaucoma diagnosis for detecting functional defects from glaucomatous optic neuropathy. Because achromatic perimetry is only able to detect scotomas after loss of up to 30-40% of retinal ganglion cells, early diagnosis using this method is rarely possible...
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PMID: 19343353
PDF is available here.
Abstract
The purpose of this study is to evaluate the diagnostic value of optical coherence tomography (Stratus OCT) and scanning laser ophthalmoscope (SLO) microperimetry in patients with Stargardt's disease (STGD), and the correlation between macular morphology and visual function in these...
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PMID: 18941768
PDF is available here.
Abstract
To compare visual field progression in glaucoma patients assessed by the glaucoma progression analysis (GPA) used in the Humphrey Field Analyzer perimeter and by objective clinical criteria.
Retrospective cross-sectional study of 93 eyes of 93 consecutive glaucoma pat...
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PMID: 18982343
PDF is available here.
Abstract
Characteristic signs are loss of visual acuity, photophobia and central scotoma. The diagnosis of cone dystrophy is determined by a full-field electroretinogram (ERG). Fundus and near-infrared autofluorescence as well as optical coherence tomography allow detection of retinal structural abnormalitie...
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PMID: 19190919
PDF is available here.
Abstract
3D-CTAG abnormalities were detected in six patients (16%) who had no abnormalities with conventional Amsler grid testing. DME patients had more foci of CVF deficits (3.56 +/- 2.92 defects/eye), than AMD patients (1.24 +/- 0.89 defects/eye; P < 0.0002). The shape of the 3D-CTAG abnormality in DME was...
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PMID: 18958487
PDF is available here.
Abstract
Although older patients presenting with acute posterior multifocal placoid pigment epitheliopathy-like lesions are likely to experience visual improvement as acute lesions resolve, geographic atrophy and choroidal neovascular membrane formation may subsequently develop, leading to moderate or severe...
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PMID: 19202424
PDF is available here.
Abstract
There is a local reduction in retinal function in the area of retained subretinal PFCL. There may be partial recovery of retinal function in an area vacated by the subretinal PFCL. Subretinal PFCL beneath the fovea or at risk for migration beneath the fovea should be considered for removal....
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PMID: 18854788
PDF is available here.
Abstract
Sensitivity, specificity, and false-positive and false-negative results were calculated for each method. Fluorescein fundus angiography and infrared imaging, although using different approaches, both detect pigment epithelium changes such as laser scars. It seems that both methods are of equal speci...
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PMID: 19634743
PDF is available here.
Abstract
An unusual case of traumatic maculopathy following blunt trauma with a sugarcane stick is reported in a 12-year-old boy. An area of parafoveal exudates associated with decrease in visual acuity was observed in the affected eye of the patient. Baseline parameters related to the best-corrected visual...
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PMID: 19634752
PDF is available here.
Abstract
The authors present the case of a 76-year-old man with excised colon carcinoma, who has remained with zones of high grade metaplasia even after the surgery and who came in our Clinic for declined vision in both eyes, progressive and more obvious in the left eye and the presence of an absolute scotom...
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PMID: 19899553
PDF is available here.
Abstract
The 3D test identified and characterized scotomas typical of glaucoma. The test provides several advantages over conventional perimetry including additional information through 3D depiction of scotomas with the addition of contrast sensitivity and a higher angular/spatial resolution. Improved patien...
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PMID: 19787597
PDF is available here.
Abstract
Subthreshold diode laser is effective in the treatment of ICSC with point source leakage. However, for eyes with diffuse leakage, a less favorable response was noted. A multicenter, randomized clinical trial is needed to ascertain the real efficacy and the appropriate settings of SMD for chronic ICS...
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PMID: 19041477
PDF is available here.
Abstract
The psychophysical correlate of beta zone of parapapillary atrophy is an absolute scotoma, and the correlate of alpha is a relative scotoma. It agrees with the histological correlate of beta zone with a complete loss of retinal pigment epithelium cells and photoreceptors, and with the histological c...
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PMID: 18782800
PDF is available here.
Abstract
Implantation of the double IOL system improved BCVA in patients with low vision due to advanced maculopathy. The results were best in myopic patients (long eyes); patients with hyperopia (short eyes) had high residual refraction. The postoperative clinical gain and residual refraction were predictab...
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PMID: 18721722
PDF is available here.
Abstract
Perceptual filling in is facilitated at the corresponding area of retinal scotomas. The neural mechanisms of this visual facilitation might be similar to those found following somatosensory cortex partial deafferentation....
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PMID: 18621793
PDF is available here.
Abstract
We report the follow-up of a case of choroideremia who underwent three white-on-white automated visual field and three scanning laser polarimetry (SLP) examinations by means of a GDx VCC in the course of one year. A bilateral perimetric deterioration in indices and scotomas was found. As a result, r...
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PMID: 18661445
PDF is available here.
Abstract
This study investigated the relationship between reading speed and oculo-motor parameters when normally sighted observers had to read single sentences with an artificial macular scotoma. Using multiple regression analysis, our main result shows that two significant predictors, number of saccades per...
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PMID: 18601944
PDF is available here.
Abstract
We previously reported large-scale reorganization of visual processing (i.e., activation of "foveal" cortex by peripheral stimuli) in two individuals with loss of foveal input from macular degeneration [Baker, C.I., Peli, E., Knouf, N., & Kanwisher, N. G. (2005). Reorganization of visual processing...
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PMID: 18620725
PDF is available here.
Abstract
CASE REPORT: A 56-year-old woman with a right optic nerve sheath meningioma and visual loss, was treated with fractionated stereotactic radiotherapy. This resulted in an almost complete recovery of her visual acuity. DISCUSSION: Currently there are many different alternatives available for the manag...
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PMID: 18592446
PDF is available here.
Abstract
OCT and fundus-related perimetry allow a correlation to be defined between foveal thickness and visual function and are useful tools to define better the degree of anatomic and functional impairment in AFVD patients....
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PMID: 18439561
PDF is available here.
Abstract
There were 18 evaluable eyes among one patient with MEWDS, two with AZOOR, and seven with MCP. In the 14 eyes with blind spot enlargement [corrected] corresponding IS/OS boundary defects were found in the [corrected] peripapillary region, while no IS/OS boundary defects were found in the four [corre...
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PMID: 18439564
PDF is available here.
Abstract
Two main conclusions were drawn. First, the role of peripheral vision in inducing vection is enhanced in people with bilateral central vision loss. Second, people with bilateral AMD adapt successfully to a moving environment (they do not experience vection longer, nor do they tilt more) and are more...
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PMID: 18390642
PDF is available here.
Abstract
We present a case of potential cytotoxicity of epiretinal TA deposits in vivo. CASE REPORT: A 68-year old patient underwent a re-vitrectomy with peeling of a macular pucker and the internal limiting membrane (ILM) combined with an intravitreal injection of 25 mg TA due to a secondary macular pucker...
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PMID: 17955246
PDF is available here.
Abstract
Areas of reduced AF are measurable, but are not equivalent to the area of dense scotoma in 53% of patients. Measures of retinal sensitivity and scotomas are necessary for defining retinal functional involvement in Stargardt disease....
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PMID: 18536594
PDF is available here.
Abstract
The patients' age ranged from 55 to 85 years and BCVA ranged from 20/20 to 20/400. In patients with early AMD, fixation was foveal and stable, with presence of a relative or absolute scotoma in correspondence with the abnormal retinal areas. In eyes with dry AMD, an absolute scotoma corresponding to...
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PMID: 18641585
PDF is available here.
Abstract
The coordination of foveal fixation and finger placement found with the SLO method was similar to that found by others using eyetracking techniques with visually normal subjects. The presence of a central scotoma and use of a PRL caused marked deterioration in the quality of this coordination. Unlik...
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PMID: 18382342
PDF is available here.
Abstract
Central scotomas and retinal nerve fibre bundle defects are the most common VFDs in acute ON. Small central and paracentral scotomas that most probably would have been missed by automated thresholding perimetry with its relatively coarse grid could be detected by threshold-related, slightly supralim...
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PMID: 18239928
PDF is available here.
Abstract
Age-related macular degeneration is a chronic disease leading to progressive central vision loss. It is the leading cause of irreversible blindness in the United States, most commonly affecting white Caucasians aged more than 55 years. Typical symptoms include decreased central vision, central scoto...
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PMID: 18374683
PDF is available here.
Abstract
Surgical closure of Nd:YAG induced macular holes should be delayed to allow spontaneous closure. Photodynamic therapy was successful in treating choroidal neovascularization in this case....
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PMID: 18412221
PDF is available here.
Abstract
We herein describe for the first time, to our knowledge, the utility of high-resolution retinal imaging in studying the photoreceptor mosaic in an otherwise unexplained visual disturbance. Imaging of the cone mosaic was performed in a 64-year-old man with a unilateral ringlike paracentral distortion...
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PMID: 18413527
PDF is available here.
Abstract
His corrected visual acuities were 20/800 OD and 20/200 OS. A Goldmann visual field examination showed ceco-central scotomas in both eyes. OCT using a peripapillary Fast RNFL (retinal nerve fiber layer) programme showed a small decrease in the RNFL thickness of the superotemporal quadrant in the nor...
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PMID: 17435689
PDF is available here.
Abstract
We present a case study examining the eye movements of a subject with Stargardt's disease causing bilateral central scotomas, while performing a set of natural tasks including: making a sandwich; building a model; reaching and grasping; and catching a ball. In general, the subject preferred to use P...
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PMID: 18339049
PDF is available here.
Abstract
These quantitative differences implicate different mechanisms for perceptual completion over pathologic and physiological retinal scotomas. Filling in across pathologic scotomas appears to involve higher level image processing-based mechanisms that operate even when their input is interrupted. Filli...
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PMID: 19029023
PDF is available here.
Abstract
Rod function may be more severely affected than cone function in patients with group 2A idiopathic juxtafoveal retinal telangiectasia, and this may occur early in the disease progression. Severe reduction in retinal sensitivity is spatially confined to morphological alterations seen with scanning la...
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PMID: 18332311
PDF is available here.
Abstract
Hydroxychloroquine sulfate (Plaquenil; Sanofi-Aventis, Bridgewater, New Jersey) is an antimalarial agent, which is sometimes used for the treatment of certain autoimmune disorders. Its use has been associated with ocular side effects; the most concerning is toxic maculopathy....
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PMID: 18215798
PDF is available here.
Abstract
Both techniques revealed deficits in visual function across the visual field in strabismic amblyopes, but the mfVEP revealed deficits in fellow eyes and in more amblyopic eyes. In addition, mfVEP response latencies for amblyopic eyes were shorter than normal....
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PMID: 17651996
PDF is available here.
Abstract
We attempt to explain why this formerly well-known clinical phenomenon was forgotten later for nearly a century....
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PMID: 18387550
PDF is available here.
C M Chisholm,
F G Rauscher,
D C Crabb,
L N Davies,
M C Dunne,
D F Edgar,
J A Harlow,
M James-Galton,
A Petzold,
G T Plant,
A C Viswanathan,
G J Underwood and
J L Barbur
Abstract
Although the IVF and EVFT agree well in classifying visual fields with regard to legal fitness to drive in the UK, the IVF "passes" some individuals currently classed as unfit to drive due to paracentral scotomata of non-glaucomatous origin. The suitability of the UFOV for assessing crash risk in th...
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PMID: 17962396
PDF is available here.
Abstract
Focal neurologic symptoms in healthy pregnant women are frequently preceded by aural visual phenomena and can usually be attributed to a first-ever migraine attack. Cerebral ischemia is less common than migraine and can be reliably diagnosed with MRI. Extensive evaluations to assess a putative hyper...
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PMID: 18268190
PDF is available here.
Abstract
We have recently shown that a temporal property of letter recognition--the exposure time required for a high level of accuracy--is also a factor limiting reading speed in AMD [Cheong, A. M. Y., Legge, G. E., Lawrence, M. G., Cheung, S. H., & Ruff, M. (2007). Relationship between slow visual processi...
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PMID: 18191983
PDF is available here.
Abstract
symptoms in renovascular hypertension don't have pathognomonic clues and the identified signs, one type or all together, enforce the evaluation or even the monitoring of the arterial tension at least 30 days. If the values exceed the normal, complex investigations will be made in order to determine...
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PMID: 18717279
PDF is available here.