Abstract
We evaluated whether hypothermia can decrease ischemic injury if it is induced after incomplete ischemia. Rats were anesthetized with 1.4% inspired isoflurane, and ischemia was produced by right carotid ligation combined with hemorrhagic hypotension to 30 mm Hg for 30 min. Hypothermia (31 degrees...
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PMID: 10147757
PDF is available here.
Abstract
We review the pathology of Lyme disease in man beginning with the tick bite. We present the pathologic changes of the rash, erythema migrans, as well as the neurologic, cardiac, and arthritic changes of the disease. We can expand our understanding of the immunobiology of Lyme disease by studying the...
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PMID: 2690468
PDF is available here.
Abstract
Two different derivatives of the 17D strain of yellow fever (YF) vaccine virus, i.e. ALV-free seed virus 6676 and three consecutive vaccine lots, A, B and C, obtained from another seed, were compared in monkey neurovirulence tests using rhesus and cynomolgus monkeys. In addition the ALV-contaminated...
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PMID: 3680299
PDF is available here.
Abstract
Depending on methods of delivery, 7-50% of all children are born with retinal haemorrhages (RH). To assess the prognostic value of extensive RH for the future development of the child, the ophthalmological, neurological and psychological status of 52 children, 26 born with RH and 26 controls, were e...
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PMID: 3661176
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Abstract
The presenting symptoms of Wilson disease and its natural history as related to age are described based on 283 cases collected in Japan. The disease presented with a variety of signs and symptoms; the most frequent were in order of frequency jaundice, dysarthria, clumsiness, tremor, drooling, gait d...
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PMID: 3595645
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Abstract
Patients with late effects of poliomyelitis, i.e., PPS, are being seen at an ever increasing frequency by general physicians, neurologists, and orthopedists. An appropriate time interval for the onset of late manifestations has elapsed since the major epidemics of poliomyelitis in the 1940s and 1950...
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PMID: 3315237
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Abstract
The neurological manifestations and toxicities of 12 antituberculosis drugs [isoniazid, rifampicin (rifampin), ethambutol, p-aminosalicylic acid, pyrazinamide, streptomycin, kanamycin, ethionamide, cycloserine, capreomycin, viomycin and thiacetazone] are reviewed. Their effects upon the central nerv...
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PMID: 3547005
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Abstract
Although rare, hypertensive crises may rapidly lead to irreversible organ damage or death. Their prompt recognition, based primarily on physical signs and symptoms, is essential. Appropriately aggressive therapy, and evaluation of precipitating and exacerbating conditions, will often result in a sat...
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PMID: 3520183
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Abstract
The clinical features of caprine beta-mannosidosis were evaluated in 10 newborn goats, one stillborn goat and one goat fetus. The phenotypic abnormalities observed in all 10 live affected animals included an inability to rise from a recumbent position, moderate to marked intention tremor, eye moveme...
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PMID: 2939617
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Abstract
In 303 subjects, amongst whom 250 patients suspected of suffering from the hyperventilation syndrome, lung functions were measured, a hyperventilation provocation test was performed and a questionnaire was taken. The subjects were subdivided into categories of nonhyperventilators, and 3 categories o...
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PMID: 3081975
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Abstract
One hundred and twenty-two chronic alcoholics were examined neurologically after more than 14 days of abstinence. A high frequency of the following was noted: abnormal smooth pursuit eye movement, hyperreflexia, snout reflex, incoordination, and signs suggesting peripheral neuropathy. Some significa...
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PMID: 3837952
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Abstract
Neostigmine-induced muscle fasciculations, quantitated as fasciculatory muscle action potentials, served as an indirect in vivo indicator of motor nerve ending (MNE) excitability. By this method, MNE excitability was depressed in adrenalectomized rats compared to matched intact controls. Daily or co...
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PMID: 4078737
PDF is available here.
Abstract
Folate deficiency has become a popular topic in geriatric literature recently. There are two main reasons for this interest: folate deficiency is prevalent among the elderly population, and many chronically ill elderly patients suffer from hematologic or neuropsychiatric disorders of which folate de...
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PMID: 3913517
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Abstract
The mean age of the 13 patients studied (9 women, 7 men) was 50.5 +/- 15.7 years. The disease was discovered on account of malaise (3 cases), behavioural disorders (4 cases), coma (3 cases), syncope (1 case) or right hemiparesis (1 case) or in the course of systematic examination (1 case). Eleven pa...
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PMID: 2999755
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Abstract
Hyperosmolar nonketotic coma occurs most frequently in the elderly patient with underlying renal impairment. It often has an insidious onset, and may be precipitated by an identifiable illness, medication or procedure. Various neurologic manifestations may occur and obscure the diagnosis. Rapid reco...
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PMID: 4025102
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Abstract
The serendipitous discovery of a new species of fungi T inflatum Gams coupled with the diligent investigations of Borel to dissect the immunosuppressive action of CsA have yielded a new reagent of compelling therapeutic moment. Due to its relatively specific inhibition of lymphokine generation by T...
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PMID: 3161230
PDF is available here.
Abstract
Our findings demonstrate that subtle neurologic abnormalities may appear as early as at two months of age and that developmental abnormalities may occur even in the absence of episodes of overt metabolic decompensation. Since screening and treatment are both inexpensive and effective and the inciden...
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PMID: 4000223
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Abstract
A 59-year-old female of facial myokymia with multiple sclerosis was reported. In this case, facial myokymia appeared at the same time as the first attack of multiple sclerosis, in association with paroxysmal pain and desesthesia of the neck, painful tonic seizures of the right upper and lower extrem...
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PMID: 4041289
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Abstract
Indications, results, techniques, laboratory monitoring and complications of therapeutic plasmapheresis in patients with symptomatic paraproteinemia are reviewed. In paraproteinemia associated with severe complications plasma-pheresis has been used successfully as an emergency treatment, as a treatm...
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PMID: 3890984
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Abstract
During a 12-month prospective study there were 125 visits to the Harlem Hospital Emergency Room for symptomatic hypoglycemia. Sixty-five patients had obtundation, stupor, or coma; 38 had confusion or bizarre behavior; 10 were dizzy or tremulous; 9 had had seizures; and 3 had suffered sudden hemipare...
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PMID: 4004166
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Abstract
Ataxia-telangiectasia (A-T) is a clinical syndrome that commonly shows oculocutaneous telangiectasia, progressive cerebellar ataxia, recurrent sinopulmonary infections, increased incidence of malignancy, x-ray hypersensitivity, and autosomal recessive inheritance. Profound dysfunction of both humora...
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PMID: 2580869
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Abstract
In order to determine whether the calcium blockers verapamil and/or magnesium sulfate decrease neurological morbidity after cardiac arrest, all out-of-hospital cardiac arrests (290) occurring during a nine-month period in five participating hospitals were retrospectively studied. Twenty-nine patient...
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PMID: 3882095
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Abstract
The physical properties of lightning are given, including a description of the different observed lightning forms. The wide variety of effects of lightning on humans is reviewed. In the prehospital care of those struck by lightning, emphasis is upon immediate resuscitation of those who appear unresp...
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PMID: 3910718
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Abstract
Since 1981 a highly contagious viral disease causing high morbidity and low mortality in racing pigeons has spread over Europe. The virus belongs to the avian paramyxovirus sero group I. Clinical signs include watery droppings, polydypsia and neurologic signs in a high proportion of infected animals...
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PMID: 2983486
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Abstract
Nowadays, extradural vertebral neoplasms which compress the spinal cord are being diagnosed earlier and therefore laminectomy for decompression relieves many patients of their neurological deficits before permanent cord damage has set in. In addition, radiotherapy and oncological treatment have prol...
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PMID: 2420950
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Abstract
We found a significantly higher prevalence of false positive VDRL (p less than 0.01), lupus-like anticoagulant (p less than 0.05), and AMA type M5 (p less than 0.01), but not of anti-ds or ss-DNA antibodies. Three sera positive for ACA, AMA-M5 and anti ss-DNA were absorbed with cardiolipin liposomes...
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PMID: 4085163
PDF is available here.
Abstract
Facial myokymia was evident in a 57-year-old man exhibiting both clinical and radiological signs of obstructive communicating hydrocephalus. Insertion of a ventriculoatrial shunt resulted in resolution of clinical symptomatology including the facial myokymia. Since there was no evidence of a structu...
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PMID: 3979415
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Abstract
Thirty-two patients with myelomatosis (3 with a solitary plasmocytoma and 29 with multiple myeloma) and neurological complications, from a group of 110 unselected patients with myelomatous disease were recorded. Spinal cord compression was the most frequent complication seen in 12 cases. In 9 subjec...
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PMID: 3868689
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Abstract
A 6 3/4-year-old boy with neuronopathic Gaucher's disease died unexpectedly. Autopsy demonstrated unusual vascular findings with the presence of Gaucher's cells and intimal-medial fibrosis in the ascending aorta and widespread acute hemorrhagic necrosis of the left ventricular myocardium. The combin...
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PMID: 3838241
PDF is available here.
Abstract
Fifty-eight cases presenting a tethered conus with spina bifida occulta are analysed. Twenty-three patients had a lipoma, the others had various malformations of the cord. Twenty patients had no symptom or sign, 38 had neurological symptoms and signs. Only 2 had no skin malformation. The aim of surg...
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PMID: 3890073
PDF is available here.
Abstract
Two hundred ninety-eight arterial injuries in 269 upper extremities were reviewed. Penetrating agents accounted for 250 injuries (93 percent) and blunt trauma for 19 (7 percent). Fifty-nine axillary, 126 brachial, 65 radial, and 48 ulnar arteries were damaged. Twenty-six extremities had more than on...
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PMID: 6507753
PDF is available here.