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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Brain Stem (4):
Recent article
Brain Stem
Abstract
We combined fluorescent retrograde tracing of CeA projections to nuclei that modulate fear-related freezing or cardiovascular responses with in vitro electrophysiological recordings and with in vivo monitoring of related behavioral and physiological parameters. CeA projections emerged from separate...
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PMID: 21719680
PDF is available here.
PDF is available here.
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Autonomic Neuroscience (159)1-2 2011
Abstract
We tested the hypothesis that γ-aminobutyric acid (GABA) mediated neurotransmission within the NTS produces an inhibition of the baroreflex response of splanchnic sympathetic nerve discharge (sSND). In urethane-anesthetized, artificially ventilated and vagotomized male SHR and Wistar Kyoto (WKY) ra...
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PMID: 20837402
PDF is available here.
PDF is available here.
Abstract
We provide evidence that a discrete subtype of medulloblastoma that contains activating mutations in the WNT pathway effector CTNNB1 (hereafter, WNT subtype) arises outside the cerebellum from cells of the dorsal brainstem. We found that genes marking human WNT-subtype medulloblastomas are more freq...
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PMID: 21150899
PDF is available here.
PDF is available here.
Abstract
We particularly focus on the role of the brainstem and spinal cord in the control of postural muscle tone and generation of locomotor rhythm. Abnormalities in the convergence inputs from the forebrain structures to the brainstem-spinal cord are further discussed in relation to the pathogenesis of di...
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PMID: 21068448
PDF is available here.
PDF is available here.
Abstract
We have attempted to discover ideal world laws wherein we can consider nature as homogeneous. The real world, however, is by far more complicated than what natural sciences have so far been able to decipher. There are many problems that cannot be effectively addressed with the existing scientific te...
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PMID: 21068454
PDF is available here.
PDF is available here.
Abstract
We examined sleep and wakefulness in mice deficient in a homeobox transcription factor, Goosecoid-like (Gscl), which is one of the genes deleted in DiGeorge syndrome or 22q11 deletion syndrome. The expression of Gscl is restricted to the interpeduncular nucleus (IP) in the ventral region of the midb...
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PMID: 20921407
PDF is available here.
PDF is available here.
Biological Psychiatry (68)6 2010
Abstract
We investigated the influence of CACNA1C polymorphisms on brain structure.
In 585 healthy volunteers, for whom magnetic resonance imaging data at 1.5 T (n = 282) or 3 T (n = 304) were available, we tested 193 single nucleotide polymorphisms (SNPs) in or near CACNA1C for association with FSL FIRST-se...
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PMID: 20638048
PDF is available here.
PDF is available here.
Abstract
The multiple auditory steady-state response (multiple ASSR) is a promising technique for determining thresholds for infants and children. However, there are few data for infants and young children with hearing loss where multiple-ASSR thresholds have been compared to frequency-specific gold standard...
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PMID: 21034700
PDF is available here.
PDF is available here.
Abstract
The role of evoked potential (EP) in evaluating multiple sclerosis (MS) has changed with the advent of magnetic resonance (MR) imaging. Given the possibly varied nature and distribution of pathologic lesions in Asian MS, this study compared the diagnostic usefulness of EPs to that of MR imaging amon...
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PMID: 20938612
PDF is available here.
PDF is available here.
Neuroscience (169)2 2010
Abstract
We combined retrograde tracing with immunohistochemistry for the neurotransmitter glycine. We deposited a retrograde tracer at recording sites displaying either high best frequencies (>75 kHz) in conjunction with combination-sensitive inhibition, or at sites displaying low best frequencies (23-30 kH...
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PMID: 20451586
PDF is available here.
PDF is available here.
Abstract
To determine the incidence and predictive factors for the development of hydrocephalus in patients with acoustic neuromas (AN) treated with fractionated stereotactic radiotherapy.
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PMID: 20675080
PDF is available here.
PDF is available here.
Abstract
We evaluated cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5-MTHF), biogenic amines, and white matter status in six Kearns-Sayre syndrome (KSS) patients. They presented severe 5-MTHF deficiency. A significant negative correlation was observed between CSF 5-MTHF and protein concentration. CSF h...
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PMID: 20388557
PDF is available here.
PDF is available here.
Abstract
We found that astrocytes of the brainstem chemoreceptor areas are highly chemosensitive. They responded to physiological decreases in pH with vigorous elevations in intracellular Ca2+ and release of adenosine triphosphate (ATP). ATP propagated astrocytic Ca2+ excitation, activated chemoreceptor neur...
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PMID: 20647426
PDF is available here.
PDF is available here.
Abstract
The effect of selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro), which is a synthetic derivative of the endogenous tetrapeptide tuftsin (stable with respect to tissue peptidases), on the learning and memory processes and metabolism of serotonin (5-HT) have been experimentally studied on Wistar rats. The animals...
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PMID: 20919548
PDF is available here.
PDF is available here.
Journal of Neurosurgery (113)2 2010
Abstract
The present study provides quantitative analysis of cannula placement and infusate distribution using real-time MR imaging and defines an optimal zone for infusion in the nonhuman primate thalamus and brainstem. Cannula placement recommendations developed from such translational nonhuman primate stu...
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PMID: 20367078
PDF is available here.
PDF is available here.
Brain research (1345) 2010
Abstract
We used LepRb-GFP reporter mice in combination with muscle-specific injection of an mRFP-expressing pseudorabies virus (PRV), which acts as a transsynaptic retrograde tracer. Consistent with previous observations in the rat, muscle-specific PRV injection lead to labeling within multiple areas of the...
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PMID: 20501326
PDF is available here.
PDF is available here.
Abstract
We demonstrate that deletion of the filamentous protein Septin 5 imparts immature synapses with striking morphological and functional features reminiscent of mature synapses. This includes synaptic vesicles tightly localized to active zones, resistance to the slow Ca(2+) buffer EGTA and a reduced nu...
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PMID: 20624595
PDF is available here.
PDF is available here.
Abstract
Preservation of function was stratified according to grade of brainstem compression. We analyzed the effect of radiosurgery on symptoms of brainstem compression. The tumor control rate was 100 % for meningioma and 97% for vestibular schwannomas (although 5% required an additional procedure such as a...
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PMID: 20381265
PDF is available here.
PDF is available here.
Nature Neuroscience (13)7 2010
Abstract
We found that vesicle endocytosis is initiated primarily in Ca(2+) nanodomains around Ca(2+) channels, where exocytosis is triggered. Bulk Ca(2+) outside of the domain could also be involved in endocytosis at immature synapses, although only after extensive exocytosis at more mature synapses. This b...
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PMID: 20562869
PDF is available here.
PDF is available here.
Abstract
We investigated whether a brainstem locomotor center, the mesencephalic locomotor region (MLR), modulates sensory transmission. The synaptic responses of brainstem reticulospinal (RS) cells to electrical stimulation of the sensory trigeminal nerve were recorded before and after electrical stimulatio...
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PMID: 20576031
PDF is available here.
PDF is available here.
Abstract
Phospholipases A(2) (PLA(2)) are enzymes which cleave the sn-2 ester bond in membrane phospholipids to release free fatty acids and lysophospholipids. The present study aimed to elucidate the expression profile of multiple secretory phospholipase A(2) (sPLA(2)) isoforms in the normal rat CNS with fo...
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PMID: 20153419
PDF is available here.
PDF is available here.
Abstract
Results of this study support the hypothesis that IL-1 can suppress REM sleep by acting at the level of the LDT nucleus. Furthermore this effect may result from the inhibition of evoked glutamatergic responses and of spontaneous firing of putative cholinergic LDT neurons....
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PMID: 20614852
PDF is available here.
PDF is available here.
Abstract
A single bout of exercise can lead to a postexercise decrease in blood pressure in hypertensive individuals, called postexercise hypotension. Compelling evidence suggests that the central baroreflex pathway plays a crucial role in the development of postexercise hypotension. This review focuses on t...
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PMID: 20577060
PDF is available here.
PDF is available here.
Abstract
Abstract
We report an unusual case in a sheep which showed immunohistochemical and molecular features of PrP(Sc) different from the other atypical cases. The sheep was from an outbreak where the index and the other four cases were affected by classical scrapie. Histopathological, immunohistochemical and West...
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PMID: 20031179
PDF is available here.
PDF is available here.
Abstract
The brainstem consists of the midbrain, pons, and medulla. The cerebellum is attached to the dorsal surface of the pons and upper medulla. The brainstem contains 9 of the 12 cranial nerves and is crossed by ascending, descending, and cerebellar pathways and their nuclei as well as the reticular form...
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PMID: 20483390
PDF is available here.
PDF is available here.
Abstract
Brainstem lesions can be classified as focal or diffuse. Magnetic resonance imaging is the most suitable imaging modality for evaluating these lesions. As a rule, focal lesions are not large and have well-defined margins. Causes include tumors, vascular malformations, demyelinating diseases, brain a...
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PMID: 20483392
PDF is available here.
PDF is available here.
Abstract
Diffuse brainstem lesions are poorly defined, often large abnormalities and include tumors (gliomas and lymphomas) vasculitis (Behçet's disease), traumatic brainstem injury, degenerative disorders (Wallerian degeneration), infections, processes secondary to systemic conditions (central pontine myel...
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PMID: 20483393
PDF is available here.
PDF is available here.
Abstract
We discuss the anatomy of the brainstem and highlight the features and landmarks that are important in interpreting magnetic resonance imaging.
Copyright 2010 Elsevier Inc. All rights reserved....
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PMID: 20483389
PDF is available here.
PDF is available here.
Abstract
Imaging of the brainstem is a real challenge from the technical point of view, because it is a very complex structure. There are gray matter nuclei with vital functions mixed to white matter tracts with very important connections, as the Cortico-Spinal Tract (CST). On the other hand, the situation o...
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PMID: 20483391
PDF is available here.
PDF is available here.
Abstract
We investigated whether DTI detects microstructural abnormalities in the brain of patients with iRBD--compared with age-matched control subjects--as an in vivo potential indicator for changes related to "preclinical (premotor)" neuropathology in PD....
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PMID: 20550017
PDF is available here.
PDF is available here.
Abstract
Neuropharmacology (58)8 2010
Abstract
We examined the effects of zolpidem on the inhibitory currents mediated by GABA(A) receptors using whole-cell patch-clamp recordings from DMV neurons in transverse brainstem slices from rat. Zolpidem prolonged the decay time of mIPSCs and of muscimol-evoked whole-cell GABAergic currents, and it occa...
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PMID: 20226798
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)22 2010
Abstract
We used global and conditional TASK channel single and double subunit knock-out mice to demonstrate definitively that TASK channels account for motoneuronal, anesthetic-activated K(+) currents and to test their contributions to sedative, hypnotic, and immobilizing anesthetic actions. In motoneurons...
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PMID: 20519544
PDF is available here.
PDF is available here.
Brain and Development (32)6 2010
Abstract
We present the young infant with the extremely rare brain abnormality-brainstem disconnection. Additionally, several extracerebral abnormalities were diagnosed: bilateral anotia, micrognatia, hypertelorism, scoliosis, ribs and vertebral anomalies. MR brain examination precisely demonstrated absence...
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PMID: 19443152
PDF is available here.
PDF is available here.
Abstract
We have examined the cellular and subcellular localization of Kv1.3 in the medial nucleus of the trapezoid body (MNTB) in the auditory brainstem, a nucleus in which neurons fire at high rates with high temporal precision. A clear gradient of Kv1.3 immunostaining along the lateral to medial tonotopic...
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PMID: 20575068
PDF is available here.
PDF is available here.
Abstract
We here document reliable magnetic activation of neurons in and near the principal (PrV) and spinal tract (SpV) nuclei of the trigeminal brainstem complex, which represent the two brain regions known to receive primary input from the trigeminal nerve. Significantly more neurons were activated in PrV...
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PMID: 20439705
PDF is available here.
PDF is available here.
Abstract
Abstract
Brain research (1328) 2010
Abstract
We investigated recovery following cardiac arrest and resuscitation in the aged rat brain. Male Fischer 344 rats (6, 12 and 24 months old) underwent 7 minute cardiac arrest before resuscitation. Overall survival and hippocampal neuronal counts were determined at 4 days of recovery. Brainstem functio...
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PMID: 20211610
PDF is available here.
PDF is available here.
Abstract
The objective of this study is to assess the relationship between brain volumes at term equivalent age and neuropsychological functions at 5 years of age in very low birth weight (VLBW) children, and to compare the results from a neuropsychological assessment and a parental questionnaire at 5 years...
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PMID: 19821136
PDF is available here.
PDF is available here.
Abstract
Abstract
We investigated the effects of mutant human SOD1 protein on global gene expression in the spinal cord and lower brain stem of presymptomatic TgSOD1(G93A) transgenic mice. One hundred twenty transcripts were found to be significantly dysregulated in the presence of mutant SOD1 protein, 79 being down-...
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PMID: 19953340
PDF is available here.
PDF is available here.
Abstract
We present the case of a newborn with rapidly declining hearing in the left ear within 1 month after birth. The hearing decline was associated with unilateral facial palsy. Using high-resolution computed tomography (CT) of the temporal bone, we diagnosed the patient with congenital internal auditory...
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PMID: 19762506
PDF is available here.
PDF is available here.
Neurosurgery (66)5 2010
Abstract
We present evidence that he concealed another neuronanatomic structure in the final panel of this series, the Separation of Light From Darkness, specifically a ventral view of the brainstem. The Separation of Light From Darkness is an important panel in the Sistine Chapel iconography because it depi...
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PMID: 20404688
PDF is available here.
PDF is available here.
Folia morphologica (69)2 2010
Abstract
The study was conducted to evaluate the sexual dimorphism in the morphometric parameters of the whole brain and the brainstem in adult captive African giant pouched rats. Twenty-nine brain samples, comprising 15 females and 14 males, were utilized. Following brain extraction by standard procedures,...
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PMID: 20512755
PDF is available here.
PDF is available here.
Folia morphologica (69)2 2010
Abstract
We estimated distances at the level of the pons and midbrain, based on axial cross-sections, according to standard radiological protocol. The parameters included the width of the AC in its anterior and posterior part, the width of the tentorial notch, and the distance from the pons and sella. All me...
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PMID: 20512757
PDF is available here.
PDF is available here.
Abstract
These results show that chronic exposure to environmentally relevant levels of MeHg disrupts GABAergic signaling. Given that GABA is the main inhibitory neurotransmitter in the mammalian nervous system, prolonged disruptions of its function may underlie the sub-clinical impacts of MeHg at relevant l...
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PMID: 20060493
PDF is available here.
PDF is available here.
Abstract
We tested the 8H9scFv-PE38 recombinant Pseudomonas immunotoxin in a preclinical model of high-grade glioma. The half maximal inhibitory concentration (IC(50)) of 8H9scFv-PE38 in vitro was determined using glioblastoma cell lines U87 and U251. Maximum tolerated infusion dose of 8H9scFv-PE38 following...
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PMID: 20371725
PDF is available here.
PDF is available here.
Journal of Neurotrauma (27)4 2010
Abstract
We studied recovery curves of the blink reflex (BR) to paired suprathreshold stimuli at various intervals (160, 300, 500, and 1000 msec), and prepulse inhibition of the BR following right index finger stimulation 100 msec prior to supraorbital nerve stimulation. Both parameters were studied in patie...
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PMID: 20067395
PDF is available here.
PDF is available here.
Rinsho Shinkeigaku (50)4 2010
Abstract
We report the case of a 30-year-old man who developed severe dysphagia owing to neuroborreliosis. He showed dysphagia, diplopia, hiccups, and walking difficulty Neurological examination revealed mild disturbance of consciousness, diplopia on left lateral gaze, left-side-dominant blephaloptosis, gaze...
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PMID: 20411811
PDF is available here.
PDF is available here.
Pediatric Neurology (42)4 2010
Abstract
We report on an infant with multiple cranial-nerve involvement attributable to brainstem dysgenesis, born to a cocaine-addicted mother.
Copyright 2010 Elsevier Inc. All rights reserved....
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PMID: 20304337
PDF is available here.
PDF is available here.
Neuropeptides (44)2 2010
Abstract
We also observed significant amount of specific labelling remaining even after having blocked all known NPY receptor subtypes targeted by radioligands such as [(125)I][Leu(31), Pro(34)]PYY, [(125)I]PYY3-36 and [(125)I]hPP. This binding is referred as an atypical NPY site. Lipopolysaccharide (LPS) in...
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PMID: 19880180
PDF is available here.
PDF is available here.
Abstract
We compare the soluble brainstem protein complement from six summer active ground squirrels and six in the early torpor (ET) phase of hibernation. Thirteen percent of the approximately 1,500 quantifiable 2D gel spots alter significantly from summer to ET; the proteins identified in these differing s...
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PMID: 19967378
PDF is available here.
PDF is available here.
Abstract
Touch and brush sensory stimuli elicit activity in discriminative touch pathways involving specific regions in the spinal cord and brain stem. However, no study has mapped normal sensory activity noninvasively in healthy humans. The purpose of this study is to map the neuronal activi...
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PMID: 20019102
PDF is available here.
PDF is available here.
Cephalalgia (30)4 2010
Abstract
We developed a new approach for painful stimulation of the trigeminal nerve that can be implemented within an event-related design using fMRI and aimed to detect increased blood-oxygen-level-dependent (BOLD) signals as surrogate markers of trigeminal pain processing. Using an olfactometer, 20 health...
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PMID: 19673914
PDF is available here.
PDF is available here.
Cephalalgia (30)4 2010
Abstract
We developed a new approach for painful stimulation of the trigeminal nerve that can be implemented within an event-related design using fMRI and aimed to detect increased blood-oxygen-level-dependent (BOLD) signals as surrogate markers of trigeminal pain processing. Using an olfactometer, 20 health...
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PMID: 19673914
PDF is available here.
PDF is available here.
Cephalalgia (30)4 2010
Abstract
We developed a new approach for painful stimulation of the trigeminal nerve that can be implemented within an event-related design using fMRI and aimed to detect increased blood-oxygen-level-dependent (BOLD) signals as surrogate markers of trigeminal pain processing. Using an olfactometer, 20 health...
|
PMID: 19673914
PDF is available here.
PDF is available here.
Cephalalgia (30)4 2010
Abstract
We developed a new approach for painful stimulation of the trigeminal nerve that can be implemented within an event-related design using fMRI and aimed to detect increased blood-oxygen-level-dependent (BOLD) signals as surrogate markers of trigeminal pain processing. Using an olfactometer, 20 health...
|
PMID: 19673914
PDF is available here.
PDF is available here.
Cephalalgia (30)4 2010
Abstract
We developed a new approach for painful stimulation of the trigeminal nerve that can be implemented within an event-related design using fMRI and aimed to detect increased blood-oxygen-level-dependent (BOLD) signals as surrogate markers of trigeminal pain processing. Using an olfactometer, 20 health...
|
PMID: 19673914
PDF is available here.
PDF is available here.