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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Rhombencephalon (3):
Recent article
Rhombencephalon
Brain research (1350) 2010
Abstract
We have summarized recent data indicating that the multifaceted glial compartment of the brainstem should be considered in future research aimed at identifying feeding-related processes operating at this level.
2010 Elsevier B.V. All rights reserved....
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PMID: 20451504
PDF is available here.
PDF is available here.
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Endocrinology (151)7 2010
Hindbrain catecholamine neurons modulate the growth hormone but not the feeding response to ghrelin.
Abstract
We lesioned noradrenergic and adrenergic neurons that innervate the medial hypothalamus by microinjecting the retrogradely transported immunotoxin, saporin (SAP) conjugated to antidopamine-beta-hydroxylase (DSAP) into the paraventricular nucleus of the hypothalamus. Controls were injected with uncon...
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PMID: 20463049
PDF is available here.
PDF is available here.
Abstract
Amyloid positron emission tomography (PET) has recently emerged as a non-invasive neuroimaging technique for visualizing the accumulation of fibrillar amyloid-beta in the living human brain. Among several proposed radioligand tracers, Pittsburgh compound-B (PiB) has gained worldwide...
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PMID: 20675880
PDF is available here.
PDF is available here.
Developmental Biology (340)2 2010
Abstract
We present functional experiments in the mouse demonstrating that Sonic hedgehog (Shh) produced by hindbrain choroid plexus epithelium induces the extensive vascular outgrowths and vascular surface area fundamental to choroid plexus functions, but does not induce the more specialized endothelial cel...
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PMID: 20123094
PDF is available here.
PDF is available here.
médecine/sciences (26)4 2010
Abstract
Cerebellum (9)1 2010
Abstract
We present the case of a patient with Chiari II malformation mimicking partial rhombencephalosynapsis....
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PMID: 19821003
PDF is available here.
PDF is available here.
Neurosurgery (66)3 Suppl Operative 2010
Abstract
Tonsillar retraction provided a comparable exposure of the superolateral recess with tonsillar resection (26.4 +/- 17.6 vs 25.2 +/- 12.5 mm2, respectively; P = .825). Tonsillar resection significantly increased exposure of the lateral recess compared with tonsillar retraction (31.1 +/- 13.3 vs 20.2...
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PMID: 20173570
PDF is available here.
PDF is available here.
Abstract
We investigated the immunohistochemical distribution of gephyrin and the major GABA(A)R and GlyR subunits in the human light microscopically in the rostral and caudal one-thirds of the pons, in the middle and caudal one-thirds of the medulla oblongata, and in the first cervical segment of the spinal...
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PMID: 19950251
PDF is available here.
PDF is available here.
Abstract
We studied the expression of FGF receptor 3 (FGFR3) mRNA throughout early development of Xenopus laevis by RT-PCR and in situ hybridization. RT-PCR shows that FGFR3 mRNA is localized within the gastrula; regionalized staining is detected by the neural plate stage and continues throughout embryonic d...
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PMID: 20044036
PDF is available here.
PDF is available here.
Abstract
Our results suggest that the laminin-containing ventral basement membrane, dependent on the activity of the PAR-aPKC complex in the hindbrain neuroepithelium, is both a substrate for migration and a boundary that constrains facial branchiomotor neurons to the appropriate migratory path....
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PMID: 20350296
PDF is available here.
PDF is available here.
Abstract
We describe how injection of plasmid DNA encoding membrane-targeted Green Fluorescent Protein (mGFP) under the control of a ubiquitous promoter can be used for imaging cells undergoing neurulation. Central to this protocol is the methodology for imaging labeled cells at high resolution in sections a...
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PMID: 20689510
PDF is available here.
PDF is available here.
Neuroendocrinology (91)1 2010
Abstract
These results show that the adrenals regulate basal GLUT3 gene profiles in the DVC alone; during hypoglycemia, these glands suppress (DVC) or increase GLUT3 (LHA and VMH) mRNA, and selectively elevate GLUT4 transcripts in the LHA. The data demonstrate divergent adrenal control of DVC neuronal monoca...
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PMID: 19996571
PDF is available here.
PDF is available here.
Abstract
To describe the normal development of the embryonic central nervous system (CNS) using three-dimensional (3D) transvaginal (TV) ultrasound (US) between 7 and 10 w.g. and to compare the embryonic development visualized by 3D TV US with that of the classical embryology....
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PMID: 21427872
PDF is available here.
PDF is available here.
Abstract
We show that the retinoid receptor antagonist AGN193109 causes a posterior hindbrain defect in Xenopus, comparable to that seen in other vertebrates. We show that this defect arises during gastrulation. Blocking endogenous retinoid activity during gastrulation causes downregulation of the most 3' Ho...
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PMID: 20209433
PDF is available here.
PDF is available here.
Experimental Physiology (95)1 2010
Abstract
We developed a method to produce selective chronic increases in the endogenous glucocorticoid corticosterone or the glucocorticoid receptor antagonist mifepristone within the hindbrain region, which includes a key cardiovascular regulatory area, the nucleus of the solitary tract (NTS). Experiments w...
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PMID: 19748967
PDF is available here.
PDF is available here.
Developmental Neurobiology (69)11 2009
Abstract
We have discovered that the mouse midbrain has SA expressed most robustly at embryonic day (E) 12.5. SA propagation in the midbrain originates in midline serotonergic cell bodies contained within the adjacent hindbrain and then passes through the isthmus along ventral midline serotonergic axons. Onc...
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PMID: 19449313
PDF is available here.
PDF is available here.
Cerebellum (8)3 2009
Abstract
We report the results of a retrospective analysis of radiological and clinical findings in 45 cases of midbrain-hindbrain anomalies and review recent advances in embryology and molecular neurogenetics. Among 45 patients with midbrain-hindbrain malformations, 16 cases of molar tooth malformation, 12...
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PMID: 19337779
PDF is available here.
PDF is available here.
Abstract
We examined food intake in chronically maintained decerebrate rats in response to two antimetabolic drugs known to stimulate food intake, 2-mercaptoacetate (MA) and 2-deoxy-D-glucose (2DG). MA reduces fatty acid oxidation, and 2DG reduces glucose utilization. Because previous work has shown that ins...
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PMID: 19494173
PDF is available here.
PDF is available here.
Development (136)15 2009
Abstract
We identify a distinct epithelial domain in the hChP that does not express Shh, but displays Shh signaling. We find that this distinct Shh target field that adjoins a germinal zone, the lower rhombic lip (LRL), functions as a progenitor domain by contributing directly to the hChPe. By conditional Sh...
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PMID: 19570847
PDF is available here.
PDF is available here.
Abstract
We report a case of type 2 herpes simplex virus reactivation following neurosurgery of the posterior fossa. Cerebrospinal fluid analysis revealed a lymphocytic pleocytosis of over 200 x 10(6)/l. Viral reactivation should be considered in patients with fever, meningism and extended hospital admission...
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PMID: 19533470
PDF is available here.
PDF is available here.
Neurosurgical FOCUS (26)5 2009
Abstract
Aneurysms of the anterior inferior cerebellar artery (AICA) are relatively rare among intracranial aneurysms. They can occur in 1 of 3 regions of the AICA: 1) craniocaudal (high or low riding), 2) mediolateral-premeatal (proximal), and 3) meatal-postmeatal (distal). The management strategies for tre...
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PMID: 19409007
PDF is available here.
PDF is available here.
Developmental Dynamics (238)4 2009
Abstract
We isolated a novel zebrafish mutant, MHB gone (mgo), that exhibited a defective MHB. Expression of engrailed3 in the prospective MHB was absent at the 1-somite stage, suggesting that initiation of the isthmic organizer was disrupted in mgo mutants. Complementation test with mgo and noi, in which th...
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PMID: 19301393
PDF is available here.
PDF is available here.
Abstract
We report the expression pattern of Frizzled10 in mouse CNS from embryonic stages to adulthood. Frizzled10 is expressed strongly at embryonic days E8.5 and E9.5 in the neural tube and tail bud. At E10.5, Frizzled10 is expressed in the forebrain vesicle, the fourth ventricle and the dorsal spinal cor...
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PMID: 19056517
PDF is available here.
PDF is available here.
Journal de Radiologie (90)2 2009
Abstract
Child's Nervous System (25)2 2009
Abstract
Sixty-seven patients (age 11 +/- 5 years) underwent duraplasty with pericranial autograft (n = 40) or ePTFE graft (n = 27). Perioperative morbidity did not differ between cohorts. No patients receiving ePTFE graft experienced incisional CSF leak, surgical site infection, or symptomatic pseudomeningo...
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PMID: 18769929
PDF is available here.
PDF is available here.
Brain Research (1247) 2009
Abstract
We characterized brain nuclei activated during isovolumetric phasic distension of the proximal colon (10 ml, 30 s on/off for 10 min) in conscious male rats, using Fos as a marker of neuronal activation and dual immunohistochemistry to visualize co-localization of Fos expression and oxytocin (OT), ar...
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PMID: 18955037
PDF is available here.
PDF is available here.
Brain Research (1247) 2009
Abstract
Improgan, a cimetidine derivative which lacks activity at known histamine, opioid or cannabinoid receptors, acts by an unknown mechanism in the periaqueductal gray (PAG) and raphe magnus (RM) to stimulate descending, analgesic circuits. These circuits may utilize cannabinoid mechanisms. To character...
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PMID: 18983834
PDF is available here.
PDF is available here.
Abstract
In the vertebrate central nervous system, the hindbrain is an important center for coordinating motor activity, posture, equilibrium, sleep patterns, and essential unconscious functions, such as breathing rhythms and blood circulation. During development, the vertebrate hindbrain depends upon the pr...
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PMID: 19651303
PDF is available here.
PDF is available here.
Abstract
We review the cellular and molecular mechanisms underlying hindbrain neuronal circuitry in the mouse, with a specific focus on the role of the homeodomain transcription factors of the Hox gene family. The Hox genes are crucial determinants of rhombomere segmental identity and anteroposterior pattern...
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PMID: 19651304
PDF is available here.
PDF is available here.
Abstract
Hindbrain boundary cells express several signaling molecules, such as FGF3, which at earlier developmental stages is transiently expressed in specific rhombomeres. We show that chick embryos that lack boundary cells due to overexpression of truncated EphA4 receptor in the hindbrain have continued se...
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PMID: 19232109
PDF is available here.
PDF is available here.
Genetic fate-mapping approaches: new means to explore the embryonic origins of the cochlear nucleus.
Abstract
We detail materials and methods relevant to genetic fate mapping in general and intersectional genetic fate mapping in particular....
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PMID: 18839342
PDF is available here.
PDF is available here.
Developmental Biology (325)1 2009
Abstract
We use morpholino oligonucleotides to deplete the four known zebrafish RARs (raraa, rarab, rarga, and rargb). We show that while all four are required for anterior-posterior patterning of rhombomeres in the hindbrain, there are unique requirements for rarga in the cranial mesoderm for hindbrain patt...
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PMID: 18929555
PDF is available here.
PDF is available here.
Abstract
We review here recent work on: i) early patterning of the otic placode, ii) the role of neural tube signals in the patterning of the otic vesicle, and iii) the genes underlying cell fate determination of neurons and sensory hair cells....
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PMID: 19247974
PDF is available here.
PDF is available here.
Abstract
We used long-range organotypic cultures of auditory nuclei in the chick hindbrain to test the development of glutamate receptor activity in auditory neurons growing in a tissue environment that includes early deprivation of peripheral glutamatergic input, subsequent to removal of the otocyst. Cultur...
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PMID: 19200228
PDF is available here.
PDF is available here.
Abstract
We define a gene regulatory network for Hoxa2, responsible for temporal and spatial expression in hindbrain development. Hoxa2 plays an important role in regulating the regional identity of rhombomere 2 (r2) and is the only Hox gene expressed in this segment. In this study, we found that a Hoxa2 cis...
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PMID: 19104046
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)52 2008
Abstract
We report here that Lmx1b expression in mDA neurons is dispensable for their differentiation and maintenance, and the loss of mDA neurons in Lmx1b(-/-) mice is due to the disruption of inductive activity of the isthmic organizer (IsO) in the absence of Lmx1b at the mid/hindbrain boundary (MHB). We f...
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PMID: 19109492
PDF is available here.
PDF is available here.
Developmental Biology (324)2 2008
Abstract
We used time-lapse imaging of NCCs in the zebrafish hindbrain to show that NCCs undergo a stereotypical series of behaviors during EMT. We find that loss of cell adhesion and membrane blebbing precede filopodial extension and the onset of migration. Live imaging of actin dynamics shows that actin lo...
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PMID: 18926812
PDF is available here.
PDF is available here.
Developmental Biology (324)2 2008
Abstract
We show that the dynamic expression of FGF3 in chick hindbrain segments and boundaries is similar to that of the BMP antagonist, follistatin. Consistent with a regulatory relationship between BMP signaling and FGF3 expression, we find that an increase in BMP activity due to blocking of follistatin t...
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PMID: 18823972
PDF is available here.
PDF is available here.
Ophthalmology (115)12 2008
Abstract
This is the second reported patient with synergistic convergence and the first associated with a documented pathologic genotype. Unlike the previously reported case (which occurred in the setting of the cranial dysinnervation disorder congenital fibrosis of the extraocular muscles), our patient pres...
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PMID: 19041479
PDF is available here.
PDF is available here.
Abstract
Developmental Biology (324)1 2008
Abstract
We have determined the requirement for SEMA3/NRP/PLXN signalling in the development of the facial nerve, which contains axons from two motor neuron populations, branchiomotor and visceromotor neurons. Loss of either SEMA3A/NRP1 or SEMA3F/NRP2 caused defasciculation and ectopic projection of facial b...
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PMID: 18804103
PDF is available here.
PDF is available here.
Developmental Biology (324)1 2008
Abstract
We report the first attempt to define the specific contribution of the neuroectoderm to this inductive process in Xenopus. To this end we tested the ability of segments of the neural plate (NP), isolated from different axial levels, to induce the otic marker Pax8 when recombined with blastula stage...
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PMID: 18831968
PDF is available here.
PDF is available here.
Abstract
We showed that intracisternal injection of a low dose (1 microg/kg) of the 5-HT(1A) receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), significantly reduced the increases in heart rate and renal sympathetic nerve activity evoked by disinhibition of the DMH, but had no effect on th...
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PMID: 18667366
PDF is available here.
PDF is available here.
Abstract
The posterior fossa may be enlarged due to: mega cisterna magna, arachnoid cyst or Dandy Walker malformation. These anomalies can be identified during routine ultrasound screening performed in the beginning of the second half of pregnancy (22nd week). The outcome of these findings is not clear. Ther...
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PMID: 19264007
PDF is available here.
PDF is available here.
Indian Journal of Pediatrics (75)11 2008
Abstract
A 6-year-old girl who presented with developmental delay and non-progressive ataxia is described. MRI of brain showed agenesis of cerebellar vermis with fusion of cerebellar hemispheres and dentate nuclei. MRI findings were characteristic of rhombencephalosynapsis. Partial agenesis of corpus callosu...
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PMID: 18810339
PDF is available here.
PDF is available here.
Nature Neuroscience (11)11 2008
Abstract
We used conditional knockout strategies in mice to determine the developmental events and gene expression program regulated by the LIM-homeodomain factor Islet1 in developing sensory neurons. Early development of the trigeminal and dorsal root ganglia was grossly normal in the absence of Islet1. Fro...
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PMID: 18849985
PDF is available here.
PDF is available here.
Annals of Neurology (64)5 2008
Abstract
We conclude that the relation between patterns of abnormal synuclein immunostaining in the human brain and the disease entity now recognized as PD remains to be determined....
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PMID: 19067353
PDF is available here.
PDF is available here.
Developmental Neurobiology (68)12 2008
Abstract
These results suggest that progestins and progesterone receptors may play a fundamental role in the postnatal development of numerous midbrain and hindbrain nuclei, including some areas implicated in human disorders. Additionally, these findings contribute to the increasing evidence that steroid hor...
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PMID: 18712784
PDF is available here.
PDF is available here.
médecine/sciences (24)10 2008
Abstract
Abstract
Our study shows that the bHLH (basic helix-loop-helix) transcription factor Olig3 is expressed in the progenitors of RL, and ablation of Olig3 significantly affects the development of RL. In Olig3-/- caudal RL, the expression level of Math1 in the dorsal interneuron 1 (dI1) domain is reduced, and th...
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PMID: 18829970
PDF is available here.
PDF is available here.
Abstract
We use this model to test for a correlation between Fgf signaling and cell proliferation in adult progenitor zones. We report expression of Fgf signals (fgf3,4,8a,8b,17b), receptors (fgfr1-4), and targets (erm, pea3, dusp6, spry1,2,4, and P-ERK) and document that genes of the embryonic fgf8 synexpre...
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PMID: 18666124
PDF is available here.
PDF is available here.
Abstract
We examined the hnf1b(hi2169) and hnf1b(hi1843) retroviral insertion alleles. Hnf1b(hi2169) shows highly variable residual expression of several genes in r5/r6, but this is not due to full-length hnf1b transcripts persisting in hnf1b(hi2169) embryos, nor to hnf1bl, a novel hnf1 family member express...
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PMID: 18945197
PDF is available here.
PDF is available here.
Abstract
Both computed tomography and magnetic resonance imaging are valuable tools in evaluation of strabismus, despite concerns about radiation exposure with computed tomography. Advancements in magnetic resonance imaging are being made and open new techniques that can be useful in the future evaluation of...
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PMID: 18772668
PDF is available here.
PDF is available here.
Abstract
We have subjected rainbow trout (via intraperitoneal injections) to control, hyperglycemic (500 mg kg(-1) glucose body mass) or hypoglycemic (4 mg kg(-1) bovine insulin) conditions for 10 days. The experimental design was appropriate since hypoglycemia and hyperglycemia were observed the first 5 day...
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PMID: 18663455
PDF is available here.
PDF is available here.
Abstract
We show here that ZO-1 extensively colocalizes with Cx35 at identifiable "mixed" (electrical and chemical) contacts on goldfish Mauthner cells, a model synapse for the study of vertebrate electrical transmission where it is possible to correlate physiological properties with molecular composition. F...
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PMID: 18719117
PDF is available here.
PDF is available here.
Endocrinology (149)8 2008
Abstract
The effects of peripheral glucagon like peptide-1 receptor (GLP-1R) stimulation on feeding, gastric emptying, and energetic responses involve vagal transmission and central nervous system processing. Despite a lack of studies aimed at determining which central nervous system regions are critical for...
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PMID: 18420740
PDF is available here.
PDF is available here.
Journal of Physiology (586)Pt 15 2008
Abstract
We investigated if the stretch induced by a balloon at this site inhibits a rapid onset salt appetite, and if this procedure modifies the pattern of immunohistochemical labelling for Fos protein (Fos-ir) in the brain. Male Sprague-Dawley rats with SVC-RAJ balloons received a combined treatment of fu...
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PMID: 18556369
PDF is available here.
PDF is available here.
Abstract
We also measured the effect of chronic nicotine exposure on fetal blood pO(2), pCO(2), pH, Na(+) and K(+) concentrations, as well as lactic acid levels. Maternal nicotine exposure during pregnancy was associated with a decrease in fetal pO(2) coupled with a significant increase in pCO(2) and lactic...
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PMID: 18407449
PDF is available here.
PDF is available here.
Developmental Dynamics (237)8 2008
Abstract
We found reporter expression in distinct neuronal subtypes in the r7-r8-derived hindbrain. Most strikingly, hoxb4a neuronal subtypes projected through the vagus and into the pectoral fin while others formed symmetrically located fiber tracts innervating the cerebellum and the tectum, features that a...
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PMID: 18627100
PDF is available here.
PDF is available here.