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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Nerve Net (0):
Recent article
Nerve Net
Abstract
We report that early gamma oscillations (EGOs) enable precise spatiotemporal thalamocortical synchronization in the neonatal rat whisker sensory system. Driven by a thalamic gamma oscillator and initially independent of cortical inhibition, EGOs synchronize neurons in a single thalamic barreloid and...
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PMID: 21998388
PDF is available here.
PDF is available here.
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The Lancet (378)9797 2011
Abstract
Abstract
In light of the issue of oscillation propagation in neural networks, various topologies of FitzHugh-Nagumo neuron populations are investigated. External Gaussian white noise is injected into the first neuron only. Before the oscillation spreads to the other neurons in the network, so...
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PMID: 21517527
PDF is available here.
PDF is available here.
Abstract
We identify five distinct classes of fru neuron that trigger or compose the song. Our data suggest that P1 and pIP10 neurons in the brain mediate the decision to sing, and to act upon this decision, while the thoracic neurons dPR1, vPR6, and vMS11 are components of a central pattern generator that t...
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PMID: 21315261
PDF is available here.
PDF is available here.
Abstract
We show that Notch1 and its ligand Jagged1 are present at the synapse, and that Notch signaling in neurons occurs in response to synaptic activity. In addition, neuronal Notch signaling is positively regulated by Arc/Arg3.1, an activity-induced gene required for synaptic plasticity. In Arc/Arg3.1 mu...
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PMID: 21315255
PDF is available here.
PDF is available here.
Nature Neuroscience (14)2 2011
Abstract
We review this approach and its existing and potential applications to Parkinson's disease, Tourette's syndrome, attention-deficit/hyperactivity disorder, addiction, schizophrenia and preclinical animal models used to screen new antipsychotic drugs. The approach's proven explanatory and predictive p...
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PMID: 21270784
PDF is available here.
PDF is available here.
Abstract
Chronic exposure to adverse interpersonal environment in schizophrenia is associated with vulnerability to relapse. The construct of expressed emotion (EE) measures the quality of interpersonal environment, of which criticism is a main component. To use functional magnetic resonance imaging and to i...
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PMID: 21206243
PDF is available here.
PDF is available here.
Neural plasticity (2011) 2011
Abstract
GABAergic interneurons are critical for the normal function and development of neural circuits, and their dysfunction is implicated in a large number of neurodevelopmental disorders. Experience and activity-dependent mechanisms play an important role in GABAergic circuit development,...
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PMID: 21826279
PDF is available here.
PDF is available here.
Neural plasticity (2011) 2011
Abstract
We review homeostatic plasticity of GABAergic neurons and their synaptic connections. We propose a simplistic model for homeostatic plasticity of GABAergic components of the circuitry (GABAergic synapses onto excitatory neurons, excitatory connections onto GABAergic neurons, cellular excitability of...
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PMID: 21876819
PDF is available here.
PDF is available here.
Abstract
We addressed this question by transgenically targeted ablation of proliferating oligodendrocytes during cerebellum development. Interestingly, we show that depletion of oligodendrocytes at postnatal day 1 (P1) profoundly affects the establishment of cerebellar circuitries. We observed an impressive...
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PMID: 21589880
PDF is available here.
PDF is available here.
Neural plasticity (2011) 2011
Abstract
These results raise the possibility that certain forms of synaptic plasticity may occur within the cortex while synaptic potentiation takes place within synapses in the hippocampus and amygdala. This hypothesis is supported by electrophysiological evidence obtained from freely moving animals that ne...
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PMID: 21912749
PDF is available here.
PDF is available here.
Abstract
We then present a detailed review and update of the structures involved in the phase of wakefulness (W), including their morphological, functional, and chemical characteristics, as well as their anatomical connections. The structures for W generation are known as the "ascending reticular activating...
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PMID: 21166301
PDF is available here.
PDF is available here.
Abstract
Abstract
Psychological Medicine (40)12 2010
Abstract
We assessed 18 remitted individuals with bipolar disorder, 19 of their unaffected first degree relatives and 19 healthy controls using functional magnetic resonance imaging (fMRI) and a paced verbal fluency task with two levels of difficulty.
Bipolar patients made significantly more errors in the ea...
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PMID: 20146832
PDF is available here.
PDF is available here.
Abstract
Transcallosal inhibition from the contralesional to the ipsilesional motor cortex correlated positively with motor function of the paretic hand; in contrast, transcallosal inhibition to the ipsilesional motor cortex correlated negatively with mirror activity of the paretic hand in both cortical and...
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PMID: 21031294
PDF is available here.
PDF is available here.
NeuroImage (53)2 2010
Abstract
We propose a biological cortical column model, at an intermediate mesoscopic scale, in order to better understand and interpret biological sources of voltage-sensitive dye imaging signal (VSD signal). To perform a quantitative analysis of the relative contributions to the VSD signal, a detailed comp...
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PMID: 20600993
PDF is available here.
PDF is available here.
Abstract
We introduce a novel system for recognition of partially occluded and rotated images. The system is based on a hierarchical network of integrate-and-fire spiking neurons with random synaptic connections and a novel organization process. The network generates integrated output sequences that are used...
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PMID: 21047704
PDF is available here.
PDF is available here.
Abstract
We applied structural covariance MRI techniques to 300 children in four age categories (early childhood, 5-8 y; late childhood, 8.5-11 y; early adolescence, 12-14 y; late adolescence, 16-18 y) to characterize gray matter structural relationships between cortical nodes that make up large-scale functi...
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PMID: 20921389
PDF is available here.
PDF is available here.
NeuroImage (53)1 2010
Abstract
We hypothesised that band-limited EEG power may be directly related to network-specific functional connectivity (FC) of BOLD signal time courses. Hence, we studied the association between individual EEG signature and FC in a core RSN, the so-called default mode network (DMN). Combined EEG/fMRI data...
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PMID: 20538065
PDF is available here.
PDF is available here.
Abstract
Ideggyogyaszati szemle (63)9-10 2010
Abstract
We investigate evidences supporting the network concept of epilepsies from different approaches. Firstly the functions of cortical networks in which most of the epileptic networks are embedded, are treated. Then the tentative characteristics of an epileptic network are enumerated and the conversion...
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PMID: 21033313
PDF is available here.
PDF is available here.
Brain and Language (115)1 2010
Abstract
Central nervous networks, be they a part of the human brain or a group of neurons in a snail, may be designed to produce distinct patterns of movement. Central pattern generators can account for the development and production of normal vocal signals without auditory feedback in non-songbirds. Songbi...
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PMID: 20955898
PDF is available here.
PDF is available here.
YAKUGAKU ZASSHI (130)10 2010
Abstract
We have found that pramipexole and talipexole (D(2)/D(3)-dopaminergic agonists) inhibit dopaminergic neurotoxin-induced production of reactive oxygen species and apoptotic cell death. In addition, treatment with these drugs induces enhancement of anti-apoptotic Bcl-2 expression and inhibition of α-...
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PMID: 20930477
PDF is available here.
PDF is available here.
Abstract
We use a modeling approach which is utilized to study the influence of deep brain stimulation on the restoration of segregated activity in the target structures. Besides the spontaneous activity of the target network, the model considers a weak sensory input mimicking signal processing tasks, electr...
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PMID: 20811089
PDF is available here.
PDF is available here.
Brain research (1354) 2010
Abstract
We compared false belief reasoning with true belief reasoning in children of a narrow age range between 10 and 12years and in adults. In both groups, the dorsal medial frontal cortex was activated during false versus true belief reasoning. In contrast to adults, children did not selectively recruit...
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PMID: 20678489
PDF is available here.
PDF is available here.
NeuroImage (52)4 2010
Abstract
NeuroImage (52)4 2010
Abstract
NeuroImage (52)4 2010
Abstract
We acquired quantitative T1 as well as diffusion tensor imaging (DTI) data from ten healthy subjects and ten PD patients. For each subject, the left and right SN were manually outlined on T1 images and then classified into two discrete regions based on the characteristics of their connectivity with...
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PMID: 20677376
PDF is available here.
PDF is available here.
Abstract
The spatial pattern of branches within axonal or dendritic arbors and the relative arrangement of neighboring arbors with respect to one another impact a neuron's potential connectivity. Although arbors can adopt diverse branching patterns to suit their functions, evenly spread branches that avoid c...
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PMID: 20573716
PDF is available here.
PDF is available here.
Abstract
Abstract
We focus on the brain from the perspective of a dynamic network and discuss the role of its network constituents in shaping brain dynamics. These constituents include the brain's structural connectivity, the population dynamics of its network nodes and the time delays involved in signal transmission...
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PMID: 21175008
PDF is available here.
PDF is available here.
Abstract
Early in life, brain development carries with it a large number of structural changes that impact the functional interactions of distributed neuronal networks. Such changes enhance information processing capacity, moving the brain from a deterministic system to one that is more stochastic. The evide...
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PMID: 21175017
PDF is available here.
PDF is available here.
Trends in Neurosciences (33)9 2010
Abstract
Serotonin is an important neuromodulator associated with a wide range of physiological effects in the central nervous system. The exact mechanisms whereby serotonin influences brain development are not well understood, although studies in invertebrate and vertebrate model organisms are beginning to...
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PMID: 20561690
PDF is available here.
PDF is available here.
Abstract
We discuss the various factors that enhance functional synapse formation in primary and stem cell-derived neuronal cultures. These factors include astrocytes, astrocyte-derived factors, cell adhesion molecules and neurotrophins. We discuss the current literature on studies that have used these facto...
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PMID: 20214556
PDF is available here.
PDF is available here.
Abstract
Decisions and treatment should be tailored to each individual patient and to the specific characteristics of patients. A number of available predictive models represent a tool to provide accurate prediction of cancer natural history and to improve patients' care.
(c) 2010 Wiley-Liss, Inc....
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PMID: 20623635
PDF is available here.
PDF is available here.
Abstract
We review recent studies further indicating that inhibition from parvalbumin-positive GABA neurons is necessary to produce gamma oscillations in cortical circuits; provide an update on postmortem studies documenting that deficits in the expression of glutamic acid decarboxylase67, which accounts for...
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PMID: 20556669
PDF is available here.
PDF is available here.
Abstract
INTRODUCTION: The giant fiber system (GFS) of Drosophila is a well-characterized neuronal circuit that mediates the escape response in the fly. It is one of the few adult neural circuits from which electrophysiological recordings can be made routinely. This protocol describes a simple procedure for...
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PMID: 20647357
PDF is available here.
PDF is available here.
Psychiatry Research (183)1 2010
Abstract
We used functional magnetic resonance imaging (fMRI) to study the DMN in bipolar mania and acute schizophrenia. Participants comprised 17 patients with bipolar disorder (BD), 14 patients with schizophrenia (SZ) and 15 normal controls (NC), who underwent 10-min resting fMRI scans. The DMN was extract...
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PMID: 20553873
PDF is available here.
PDF is available here.
Abstract
How do organisms select and organize relevant sensory input in working memory (WM) in order to deal with constantly changing environmental cues? Once information has been stored in WM, how is it protected from and altered by the continuous stream of sensory input and internally generated planning? T...
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PMID: 20726037
PDF is available here.
PDF is available here.
Abstract
We analysed the scale-dependent structure of cortical interactions by using maximum entropy models to characterize multiple-tetrode recordings from primary visual cortex of anaesthetized macaque monkeys (Macaca mulatta). We compared the properties of firing patterns among local clusters of neurons (...
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PMID: 20601940
PDF is available here.
PDF is available here.
Physical Review E (82)2 Pt 1 2010
Abstract
We perform a weighted network analysis to understand the effect of neurosurgery on the characteristics of functional brain networks. Statistically significant changes in network features have been discovered in the beta (13-30 Hz) band after neurosurgery: the link weight correlation around nodes and...
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PMID: 20866854
PDF is available here.
PDF is available here.
Abstract
I argue that simpler systems can combine complexity with accessibility at the cellular level. Indeed, examination of a network in fish may help in dissecting key mechanisms of complex and flexible decision-making in an established model of synaptic plasticity at the level of identified neurons....
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PMID: 20658711
PDF is available here.
PDF is available here.
Journal of Neurotrauma (27)8 2010
Abstract
We used a controlled cortical impact (CCI) model in rats to examine post-traumatic changes in neocortical excitability. Neocortical slices were prepared from rats at 7-9 days (week 1) and 14-16 days (week 2) after CCI injury. By week 2, we observed a substantial gray matter lesion with a cavity that...
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PMID: 20504156
PDF is available here.
PDF is available here.
Abstract
We show that switching one of several convergent pathways from an asynchronous to an oscillatory state allows accurate selective transmission of population-coded information, which can be extracted even when other convergent pathways fire asynchronously at comparable rates. We further show that the...
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PMID: 20670837
PDF is available here.
PDF is available here.
Abstract
We describe current theories about how interneuron diversity may support distinct neocortical processes that underlie perception.
Copyright 2010 Elsevier Inc. All rights reserved....
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PMID: 20655460
PDF is available here.
PDF is available here.
NeuroImage (51)4 2010
Abstract
We suggest that activation in this network reflects the conceptual encoding of the function of new tools as it is independent from the well-known tool-related networks. We demonstrate that understanding the function of a new tool does not rely on known semantic or motor networks involved in processi...
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PMID: 20347045
PDF is available here.
PDF is available here.
NeuroImage (51)4 2010
Abstract
We used high-resolution MRI to determine whether performance on a visual word-reading test composed of phonetically irregular words, the Wechsler Test of Adult Reading (WTAR), is associated with regional variations in cortical structure. A sample of 60 right-handed, neurologically intact individuals...
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PMID: 20302944
PDF is available here.
PDF is available here.
Abstract
We used the neocortical slow oscillation in vitro as a model system to show that weak sinusoidal and naturalistic EFs enhance and entrain physiological neocortical network activity with an amplitude threshold within the range of in vivo endogenous field strengths. Modulation of network activity by p...
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PMID: 20624597
PDF is available here.
PDF is available here.
Abstract
We define regions within LLPC by developing a parcellation scheme that integrates data from resting-state functional connectivity MRI and functional MRI. This combined approach results in a 6-fold parcellation of LLPC based on the presence (or absence) of memory-retrieval-related activity, dissociat...
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PMID: 20624599
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)28 2010
Abstract
We tested this hypothesis by measuring aspects of both functional connectivity and functional network topology derived from resting-state fMRI time series acquired at 72 cerebral regions over 17 min from 15 healthy volunteers (14 male, 1 female) and 12 people diagnosed with schizophrenia (10 male, 2...
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PMID: 20631176
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)28 2010
Abstract
We show that sponsorship of the experiment by a company endows the logo of the company with the capacity to bias revealed preference for art displayed next to the logo. Merely offering to sponsor the experiment similarly endowed the gesturing logo of the company with the capacity to bias revealed pr...
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PMID: 20631188
PDF is available here.
PDF is available here.
Journal of Neuroscience (30)28 2010
Abstract
We undertook a forward genetic screen in zebrafish (Danio rerio) to identify mutants exhibiting abnormal touch-evoked behaviors, despite the presence of sensory neurons and peripheral neurites. One family, subsequently named touché, was found to harbor a recessive mutation which produced offspring...
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PMID: 20631165
PDF is available here.
PDF is available here.
Psychological Medicine (40)7 2010
Abstract
The present study identified a common network of brain regions activated during the performance of two different forms of social judgement from faces. Dysfunction of this network is likely to contribute to the broad-ranging deficits in social function seen in psychiatric disorders such as schizophre...
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PMID: 19811702
PDF is available here.
PDF is available here.
Psychological Medicine (40)7 2010
Abstract
These data have identified a trait deficit specific to AH patients. Since this deficit was characterized within both A1 and A2 it is expected to result in the disruption of multiple auditory functions, for example, the integration of basic auditory information between hemispheres (via A1) and higher...
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PMID: 19891811
PDF is available here.
PDF is available here.
Abstract
We ask how a neural network that intrinsically generates chaotic patterns of activity can remain sensitive to extrinsic input. We find that inputs not only drive network responses, but they also actively suppress ongoing activity, ultimately leading to a phase transition in which chaos is completely...
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PMID: 20866644
PDF is available here.
PDF is available here.
Abstract
We develop a novel method that can be used to estimate the instantaneous phases and amplitudes of the alpha rhythm with high accuracy by modeling the alpha rhythm phase and amplitude as Markov random field (MRF) models. By using a belief propagation technique, we construct an exact-inference algorit...
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PMID: 20866653
PDF is available here.
PDF is available here.
Abstract
We present superconducting circuits containing Josephson junctions that model biologically realistic neurons. These "Josephson junction neurons" reproduce many characteristic behaviors of biological neurons such as action potentials, refractory periods, and firing thresholds. They can be coupled tog...
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PMID: 20866655
PDF is available here.
PDF is available here.
Abstract
We investigate how perceptual alternations during binocular rivalry are affected by spatial attention by employing a cuing paradigm. We show a tight link between the occurrence of perceptual alternations and the spatiotemporal properties of visual attention: Alternations occurred earlier and more fr...
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PMID: 20601704
PDF is available here.
PDF is available here.
Abstract
We aimed to determine the neuroanatomical correlates of changes along these different dimensions. We recorded, transcribed and analysed speech samples for 50 patients with primary progressive aphasia, along with neurodegenerative and normal control groups. Patients were scanned with magnetic resonan...
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PMID: 20542982
PDF is available here.
PDF is available here.