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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Nerve Tissue (2):
Recent article
Nerve Tissue
Abstract
In the normal brain, cellular types that compose the neurovascular unit, including neurons, astrocytes and endothelial cells express pannexins and connexins, which are protein subunits of two families that form plasma membrane channels. Most available evidence in mammals indicated th...
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PMID: 21288190
PDF is available here.
PDF is available here.
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Abstract
With the ability to form a nano-sized fibrous structure with large pore sizes mimicking the extracellular matrix (ECM), electrospinning was used to fabricate chitosan/poly(vinyl alcohol) nanofibers reinforced by single-walled carbon nanotube (SWNT-CS/PVA) for potential use in neural...
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PMID: 21702365
PDF is available here.
PDF is available here.
Abstract
The number of traffic deaths in Japan was 4,914 in 2009. Since the head was the most common site of injury in traffic accidents (2,302, 47%), traumatic brain injury causes the fatalities in these accidents. The aim of the present study was to quantify micro injuries in the animal bra...
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PMID: 21512909
PDF is available here.
PDF is available here.
Biomedical Materials (5)5 2010
Abstract
We investigated whether implantation of vascular bundles or sensory nerves affected the expression of calcitonin gene-related peptide type I receptor (CGRP1R) and neuropeptide Y1 receptor (NPY1R) in tissue-engineered bone. We implanted osteogenically induced bone marrow mesenchymal stem cells (BMSCs...
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PMID: 20826910
PDF is available here.
PDF is available here.
Abstract
We examine the evidence indicating that ASC can stimulate nerve regeneration by both undergoing neural differentiation and through the release of a range of growth factors. We also discuss some of the issues that need to be addressed before ASC can be developed as an effective cellular therapy for t...
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PMID: 19941451
PDF is available here.
PDF is available here.
Neuroscience Letters (475)2 2010
Abstract
We studied for the first time the neural differentiation of BMSCs induced by coculturing with olfactory ensheathing cells (OECs). BMSCs and OECs were isolated from bone marrow and nasal olfactory lamina propria of adult SD rats respectively, then brought to coculture with transwell culture dishes. A...
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PMID: 20347932
PDF is available here.
PDF is available here.
Neuroscience Letters (472)3 2010
Abstract
We confirmed that HP-treated adipose tissue-derived mesenchymal stem cells (HP-AT-MSCs) increased cell survival and enhanced the expression of marker genes in DsRed-engineered neural stem cells (NSCs-DsRed). Similar to untreated AT-MSCs, HP-AT-MSCs had normal morphology and were positive for the cel...
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PMID: 20153400
PDF is available here.
PDF is available here.
Abstract
Penile erection was observed in 72.73% (8/11) of the rats for (1.07 +/- 0.89) times within 30 min in the SIS graft group, as compared with 0% (0/11) of the rats for (0.00 +/- 0.00) times in the CN ablation group (P < 0.01), and 90.91% (10/11) of the rats for (2.19 +/- 1.17) times in the sham-operati...
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PMID: 20369700
PDF is available here.
PDF is available here.
Abstract
Nerves induced a polarized neurotrophic migration of cancer cells (PNMCs) along their axons, which was more efficient than in the absence of nerves (migration distance: mean = 187.1 microm, 95% confidence interval [CI] = 148 to 226 microm vs 14.4 microm, 95% CI = 9.58 to 19.22 microm, difference = 1...
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PMID: 20068194
PDF is available here.
PDF is available here.
Abstract
Our results suggest that grafting of chitosan/PGA conduits might be a promising technique for repairing peripheral nerve injuries after a 1-month delay, while introduction of NSCs seem to show no significant additional benefits to regenerative outcomes....
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PMID: 20047519
PDF is available here.
PDF is available here.
Abstract
We present a stretched sample imaging protocol that removes the dependence of MS image quality on the matrix application process and improves analyte extraction and sample desalting. First, the tissue sample is placed on a monolayer of solid support beads that are embedded in a hydrophobic membrane....
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PMID: 20680608
PDF is available here.
PDF is available here.
Abstract
We present a method developed specifically for mapping neuropeptides in crustacean neuronal tissues. Both cryostat tissue sectioning and whole-mount tissue blotting techniques are highlighted. Careful sample preparation is essential for obtaining sufficient analyte/matrix mixing while retaining the...
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PMID: 20680607
PDF is available here.
PDF is available here.
Abstract
We report a case of malignant testicular tumor presented the paraneoplastic limbic encephalitis which is one of paraneoplastic neurological syndrome....
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PMID: 20158077
PDF is available here.
PDF is available here.
Biomarkers (14)5 2009
Abstract
In vivo effects of two sublethal doses of chlorpyrifos and carbaryl were studied in Procambarus clarkii after 2 and 7 days of exposure, and after pesticide removal. Chlorpyrifos inhibited carboxylesterase activity in a concentration-dependent manner, but acetylcholinesterase was less se...
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PMID: 19476409
PDF is available here.
PDF is available here.
Abstract
Our results indicate that three-dimensional environment facilitates maturation of HUCB-derived NSC what should be considered regarding regenerative medicine application....
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PMID: 19719393
PDF is available here.
PDF is available here.
Abstract
Biomaterials prepared from polyesters of lactic acid and glycolic acid, or a mixture of the two, degrade in the presence of water into the naturally occurring metabolites, lactic acid and glycolic acid. While the lactic acid degradation product that is released from biomaterials is well tolerated by...
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PMID: 19408314
PDF is available here.
PDF is available here.
Ginekologia polska (80)8 2009
Abstract
We accept the encyclopedic definition of encephalopathy as a vast or multifocal brain lesions caused by a variety of factors, we may use the term to describe all patients with traumatic, hypoxic or toxic brain lesions, and therefore also newborns at different levels of maturity. Contrary to term new...
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PMID: 19824462
PDF is available here.
PDF is available here.
Abstract
To investigate the outcome of repairing pelvic autonomic nerve defects with the tissue-engineered nerve, in order to provide a new method and experimental evidence for solving sexual disturbance induced by pelvic autonomic nerve injury after radical resection of rectal carcinoma....
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PMID: 19296260
PDF is available here.
PDF is available here.
Abstract
We describe the cytocompatibility of a novel, micro-structured porcine collagen scaffold containing densely packed and highly orientated channels that, in three-dimensional (3D) tissue culture, supports attachment, proliferation, aligned process extension, and directed migration by populations of gl...
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PMID: 18724829
PDF is available here.
PDF is available here.
Abstract
We explore several possible antiglucocorticoid-based antidepressive therapeutic strategies. Firstly, we review specific glucocorticoid receptor/antagonist interactions. Secondly, we discuss a potential new therapeutic target, doublecortin-like kinase, which regulates glucocorticoid signaling in neur...
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PMID: 19200029
PDF is available here.
PDF is available here.
Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Journal of Reparative and Reconstructive Surgery (23)2 2009
Abstract
All the incisions were healed by first intention. Trailing status and toe's dysfunction in extension happened to the right hindlimb of rats in two groups and were improved 6 weeks after operation. General observation showed that the grafts of two groups connected well to the nerves, with appearances...
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PMID: 19275112
PDF is available here.
PDF is available here.
Cells Tissues Organs (190)6 2009
Abstract
Adipose-derived stromal cells (ASCs) include stem cells, which have the potential to differentiate into a variety of cell lineages. The regeneration of central nerves was examined using ASCs and a collagen scaffold. A cerebral cortex defect (3 x 4 x 3 mm(3)) was created in the left frontal lobe of 1...
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PMID: 19494479
PDF is available here.
PDF is available here.
Abstract
We describe the method for efficiently differentiating human embryonic stem cells to neuroepithelial cells in a chemically defined condition. The protocol was established based on the fundamental principle of in vivo neuroectodermal development. The temporal course, morphological transformation, and...
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PMID: 19378195
PDF is available here.
PDF is available here.
Cell Transplantation (18)4 2009
Abstract
We describe a simple, reliable in-house breeding protocol for the generation of accurately staged embryos as assessed by measurements of average crown to rump length (CRL)....
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PMID: 19622234
PDF is available here.
PDF is available here.
Abstract
Abstract
We show that deregulation of histone deacetylase 1 (HDAC1) activity by p25/Cdk5 induces aberrant cell-cycle activity and double-strand DNA breaks leading to neurotoxicity. In a transgenic model for neurodegeneration, p25/Cdk5 activity elicited cell-cycle activity and double-strand DNA breaks that pr...
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PMID: 19081376
PDF is available here.
PDF is available here.
Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Journal of Reparative and Reconstructive Surgery (22)12 2008
Abstract
All rats survived to the end of the experiment. At 12 and 16 weeks after the operation, group E was significantly different from group B in SFI (P < 0.05). At 20 and 24 weeks after the operation, group E was significantly different from groups B and C in SFI (P < 0.05). At 12 weeks after the operati...
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PMID: 19137896
PDF is available here.
PDF is available here.
Zhongguo Xiufu Chongjian Waike Zazhi/Chinese Journal of Reparative and Reconstructive Surgery (22)12 2008
Abstract
All rats survived after the surgery and lived to the end of the experiment. At 6 weeks after the surgery, the dynamic walking pattern of the experimental group and autologous group was better than that of the control group. The SFI value of the experimental, control and autologous groups was -51.02...
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PMID: 19137895
PDF is available here.
PDF is available here.
Abstract
We report here that NSCs can be generated from human BM-derived mesenchymal stem cells (MSCs). When cultured in NSC culture conditions, 8% of MSCs were able to generate neurospheres. These MSC-derived neurospheres expressed characteristic NSC antigens, such as nestin and musashi-1, and were capable...
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PMID: 18426339
PDF is available here.
PDF is available here.
Abstract
We developed a highly efficient methodology to produce neural stem-like and neural precursor-like cells from mice bone marrow-derived MSCs that eventually differentiate into neuronal- and glial-like cells in vitro. The aim of this study is to further elucidate neural expression profile of neurally i...
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PMID: 18484898
PDF is available here.
PDF is available here.
Zhen ci yan jiu = Acupuncture research / [Zhongguo yi xue ke xue yuan Yi xue qing bao yan jiu suo bian ji] (33)6 2008
Abstract
At normal state (before EA), PO2 values were (10.98 +/- 5.81) kPa in Governor Vessel (GV 4, GV 7 and GV 9), being significantly higher than those [(5.00 +/- 3.88) kPa, (4.74 +/- 4.23) kPa] of the left and the right control points separately. During acupuncture of GV3, PO2 value [(9.36 +/- 5.99) kPa]...
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PMID: 19288902
PDF is available here.
PDF is available here.
Abstract
We transfected human neural stem cells using lentiviral vectors encoding glial cell line derived neurotrophic factor (GDNF) to study its expression level in vitro and to get a stable cell line expressing GDNF. First, GDNF gene was sub-cloned into the lentiviral transfer vectors. Then, the recombinan...
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PMID: 19306576
PDF is available here.
PDF is available here.
Abstract
We show a novel poly(lactide-co-glycotide) (PLGA) microsphere-based spiral scaffold design with a nanofibrous surface that has enhanced surface areas and possesses sufficient mechanical properties and porosities to support the nerve regeneration process. These scaffolds have an open architecture tha...
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PMID: 18971515
PDF is available here.
PDF is available here.
Abstract
Abstract
Bridging of nerve gaps after injury is a major problem in peripheral nerve regeneration. Considering the potential application of a bio-artificial nerve guide material, polycaprolactone (PCL)/chitosan nanofibrous scaffolds was designed and evaluated in vitro using rat Schwann cells (...
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PMID: 18657027
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1779)11 2008
Abstract
We tested whether apparent changes in miRNA expression profiles may be associated with tissue processing, RNA isolation techniques, or different cell types in the sample. RNA isolation was performed on a single brain sample using eight different RNA isolation methods, and results were correlated usi...
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PMID: 18316046
PDF is available here.
PDF is available here.
Abstract
Operative surgery remains the major therapeutic modality for most serious nerve injuries, entrapments, and many nerve tumors. This article highlights the advancements that have been made in nerve surgery since World War I, including nerve action potential recording, MRI, timing of repair, grafts, tu...
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PMID: 19010277
PDF is available here.
PDF is available here.
Abstract
Nspc1 was expressed globally at the early stage. Its expression specificity began at the somites stage, mainly in the nervous system of the head. CONCLUSION: Nspc1 may play essential roles in the early stage development of zebrafish, especially in the nervous system....
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PMID: 19024384
PDF is available here.
PDF is available here.
Experimental Neurology (213)2 2008
Abstract
We report that hyperglycemia is associated with a substantial reduction in the amplitude of the slow conducting response, as well as a slowing of velocities within this very slow range (< 2.5 m/s). Even with prolonged hyperglycemia (> 4 months), histopathological abnormalities were mild and limited...
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PMID: 18687329
PDF is available here.
PDF is available here.
Abstract
We present a detailed review of the conditions affecting WM that produce these neurobehavioral syndromes, and consider the pathophysiology, clinical effects, and broad significance of the effects of aging and vascular compromise on cerebral WM, in an attempt to help further the understanding, diagno...
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PMID: 18990132
PDF is available here.
PDF is available here.
Cardiovascular Research (79)4 2008
Abstract
We review the molecular events leading to miRNA biogenesis and activity, focusing above all on endogenous and epigenetic transcriptional networks involving miRNA in early development, cellular lineage specification/differentiation of nervous, skeletal and cardiac muscle tissues and in haematopoiesis...
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PMID: 18539629
PDF is available here.
PDF is available here.
Abstract
The removal of central nervous system (CNS) tissues as part of bovine spongiform encephalopathy (BSE) risk material is one of the highest priority tasks to avoid contamination of the human food chain with BSE. No currently available method enables the real-time detection of possible CNS tissue conta...
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PMID: 18620407
PDF is available here.
PDF is available here.
Medical Science Monitor (14)8 2008
Abstract
Evidence that NPC2 is associated with severe pulmonary alveolar lipoproteinosis is supported. There were extensive neuropathological changes with storage material in swollen perikarya and a few axonal spheroids....
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PMID: 18668002
PDF is available here.
PDF is available here.
Abstract
Appendage regeneration is a complex and fascinating biological process exhibited in vertebrates by urodele amphibians and teleost fish. A current focus in the field is to identify new molecules that control formation and function of the regeneration blastema, a mass of proliferative mesenchyme that...
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PMID: 18644447
PDF is available here.
PDF is available here.
Muscle & Nerve (38)2 2008
Abstract
We report a patient who presented with the clinical features of obturator mononeuropathy. Abdomino-pelvic computed tomography revealed a fusiform mass in the right perivesical space; magnetic resonance imaging (MRI) showed characteristic "coaxial-cable-like" appearance in cross-section and "spaghett...
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PMID: 18508348
PDF is available here.
PDF is available here.
Abstract
We investigated whether repeated doses of minocycline can minimize white matter injury and neuroinflammation one week after hypoxia-ischemia (right carotid artery ligation and 30 min 6% O(2)) in the post-natal day 3 rat pup. Two dosage regimens of minocycline were administered for one week; a high d...
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PMID: 18387771
PDF is available here.
PDF is available here.
Journal of Neuroscience (28)31 2008
Abstract
We now report a virtual absence in apoE knock-out (KO) mice of normal nerve growth factor (NGF)-driven compensatory sprouting of undamaged cutaneous nociceptive nerves. In contrast, NGF-independent regeneration of crushed axons was unaffected. Essentially similar results came from aged wild-type mic...
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PMID: 18667621
PDF is available here.
PDF is available here.
Abstract
We demonstrate conserved patterns of simple covariation between sequence evolution, codon usage, and mRNA level in E. coli, yeast, worm, fly, mouse, and human that suggest that all observed trends stem largely from a unified underlying selective pressure. In metazoans, these trends are strongest in...
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PMID: 18662548
PDF is available here.
PDF is available here.
Muscle & Nerve (38)1 2008
Abstract
We present clinical, electrophysiological, and histological data from seven patients whose polyneuropathy was induced by immunoglobulin deposits in the endoneurial space. As these lesions cannot be demonstrated on clinical and electrophysiological grounds, the indication for nerve biopsy derives fro...
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PMID: 18563720
PDF is available here.
PDF is available here.
Infection and Immunity (76)5 2008
Abstract
We have reported that mice inoculated with M. ulcerans show loss of pain sensation and nerve degeneration. However, the molecules responsible for the nerve damage have not been identified. In order to clarify whether mycolactone alone can induce nerve damage, mycolactone A/B was injected to footpads...
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PMID: 18316387
PDF is available here.
PDF is available here.
Abstract
Half of the levels with PMMA showed evidence of necrosis at the bone-cement interface. Almost all (11 of 12) showed only focal necrosis, with only 1 specimen showing necrosis along the entire periphery of the PMMA. The other 12 specimens and all control levels displayed no bone necrosis. There was n...
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PMID: 18404107
PDF is available here.
PDF is available here.
Abstract
Neuromuscular Disorders (18)4 2008
Abstract
This study aimed to determine whether white matter lesions, previously described as a frequent feature in myotonic dystrophy type 1 (DM1), aggregate within DM1 families or are sporadic findings, and to explore the relationship between these lesions and clinical or genetic features. Brain MRI of 60 D...
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PMID: 18337099
PDF is available here.
PDF is available here.
Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology (138)11-12 2008
Abstract
There is increasing interest in the search for therapeutic options for diseases and injuries of the central nervous system (CNS), for which currently no effective treatment strategies are available. Replacement of damaged cells and restoration of function can be accomplished by transplantation of ce...
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PMID: 18363114
PDF is available here.
PDF is available here.
Abstract
Measurement of nerve excitability by threshold tracking provides complementary information to conventional nerve conduction studies and may be used to infer the activity of a variety of ion channels, energy-dependent pumps, and ion exchange processes activated during the process of impulse conductio...
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PMID: 18346228
PDF is available here.
PDF is available here.
Abstract
Abstract
We used a mouse model of muscle atrophy induced by complete Achilles tendon transection. Time-dependent muscle weight loss, nuclei density reduction, and extracellular matrix degeneration were observed consistently after Achilles tendon transection. Increased MMP-2 expression was confirmed at the mR...
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PMID: 17960656
PDF is available here.
PDF is available here.
Toxicology (244)2-3 2008
Abstract
To investigate the mechanisms and biomarker of the neuropathy induced by 2,5-hexanedione (HD), male Wistar rats were administrated HD at dosage of 200 or 400mg/kg for 8 weeks (five-times per week). All rats were sacrificed after 8 weeks of treatment and the cerebrum cortex (CC), spinal cord (SC) and...
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PMID: 18177991
PDF is available here.
PDF is available here.
Abstract
We evaluated the effects of chondroitinase ABC on axonal regeneration across peripheral nerve gaps. We compared axonal regeneration after 15-mm tibial nerve resection and repair with a silicone tube filled with type I collagen gel (negative control group), with a silicone tube filled with type I col...
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PMID: 18078754
PDF is available here.
PDF is available here.
NMR in Biomedicine (21)2 2008
Abstract
High b-value q-space diffusion MRS was used to study the diffusion characteristics of formalin-fixed swine optic and sciatic nerves over a large range of diffusion times (3.7-99.3 ms). The very short diffusion time range was studied with a 1 ms resolution. The displacement distribution profiles obta...
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PMID: 17492659
PDF is available here.
PDF is available here.