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Articles on Seizures
β-Hydroxybutyrate increases the pilocarpine-induced seizure threshold in young mice.
This study was designed to investigate the effects of β-hydroxybutyrate (BHB) on pilocarpine-induced seizures in young mice. Eighty-five male, postnatal day 21, ICR mice were used. All mice were pretreated with scopolamine methylbromide (1 mg/kg) 30 min prior to pilocarpine administ...
Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures.
Our results showed that the ACEA displayed a high potency and efficacy in stimulating the G-proteins and when compared to the control animals, significant enhancements were observed in tissues from the KA treated animals. Potency and efficacy values were in particular increased in the hippocampus ti...
Seizures in acute childhood stroke.
To describe the risk of seizures in children with acute stroke and identify factors predicting their later risk of epilepsy. Data for patients >3.5 years of age at a tertiary care children's hospital with acute stroke were collected and reviewed. Seven...
Aeromedical decision making and seizure risk after traumatic brain injury: longitudinal outcome.
We identified surrogate seizure markers such as all episodes of subsequent TBI, seizure, loss of consciousness, or prescription of anticonvulsant medications from the time of initial TBI until the last medical visit or entry recorded in either the database or medical records for our study population...
Emotional stress-induced seizures: another reflex epilepsy?
We present a 9-year-old girl whose seizures were provoked mainly by emotional stress. In most cases of emotional stress-related seizures, especially when a specific confrontational incidence preceded the seizure, the suspicion for a nonepileptic event is high. In our patient we were able to show tha...
Neuroanatomic correlates of psychogenic nonepileptic seizures: a cortical thickness and VBM study.
We enrolled 20 consecutive patients in whom the diagnosis of PNES was based on ictal video-electroencephalography (EEG) of the habitual episodes and 40 healthy subjects matched for age and sex All patients underwent a formal neuropsychological investigation and a neuropsychiatric assessment. All of...
CDC planning trial for mysterious nodding syndrome.
Clinical anticipation in Japanese families of benign adult familial myoclonus epilepsy.
The clinical anticipation in Japanese benign adult familial myoclonus epilepsy (BAFME), defined as earlier onset age of either cortical tremor or generalized seizures or new appearance of those symptoms in the next generation, remains unknown. The onset age and the degree of both cor...
Psychogenic nonepileptic seizures in US veterans.
PRRT2 mutations cause benign familial infantile epilepsy and infantile convulsions with choreoathetosis syndrome.
We have identified heterozygous mutations in PRRT2, which encodes proline-rich transmembrane protein 2, in 14 of 17 families (82%) affected by BFIE, indicating that PRRT2 mutations are the most frequent cause of this disorder. We also report PRRT2 mutations in five of six (83%) families affected by...