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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
DNA, Intergenic (1):
Recent article
DNA, Intergenic
Abstract
We evaluated 12 DNA extraction methods and developed a highly sensitive protocol for mycobacterial DNA extraction directly from sputa using surface-coated magnetic particles. We have also developed a novel multiplex real-time PCR for simultaneous identification of M. tuberculosis complex and the Bei...
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PMID: 21593264
PDF is available here.
PDF is available here.
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Abstract
We identify molecular events particularly likely to produce significant regulatory changes in humans: complete deletion of sequences otherwise highly conserved between chimpanzees and other mammals. We confirm 510 such deletions in humans, which fall almost exclusively in non-coding regions and are...
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PMID: 21390129
PDF is available here.
PDF is available here.
Abstract
Bacterial intergenic spacers are non-coding genomic regions enriched with cis-regulatory elements for gene expression. A population genetics approach was used to investigate the evolutionary force shaping the genetic diversity of intergenic spacers among 13 genomes of group A strepto...
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PMID: 21115137
PDF is available here.
PDF is available here.
Abstract
Brucellosis is a zoonosis caused by Brucella spp., a group of highly homogeneous bacteria. The insertion sequence IS711 is characteristic of these bacteria, and occurs in variable numbers and positions, but always constant within a given species. This species-associated polymorphism is used in molecu...
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PMID: 21813003
PDF is available here.
PDF is available here.
Abstract
Friedreich ataxia (FRDA) is the most common form of hereditary ataxia characterized by the presence of a GAA trinucleotide repeat expansion within the first intron of the FXN gene. The expansion inhibits FXN gene expression resulting in an insufficiency of frataxin protein....
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PMID: 21760943
PDF is available here.
PDF is available here.
Abstract
Multiple factors drive the progression from healthy mucosa towards sporadic colorectal carcinomas and accumulating evidence associates intestinal bacteria with disease initiation and progression. Therefore, the aim of this study was to provide a first high-resolution map of colonic d...
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PMID: 21647227
PDF is available here.
PDF is available here.
Abstract
We suggest that ITS sequences would be more suitable to serve as markers for authentication of Herba Leonuri than matK does....
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PMID: 21476215
PDF is available here.
PDF is available here.
Abstract
We are including the new species in Laetisaria based on strong statistical support for the clade containing these teleomorphs and several Marchandiomyces anamorphs. The morphological and ecological diversity of this clade indicates a potentially significant evolutionary role played by lichen-associa...
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PMID: 21193603
PDF is available here.
PDF is available here.
Abstract
We encountered a fungus sharing features of the anamorph genera Heliocephala and Holubovaniella. This hyphomycete resembled Hol. elegans in possessing obclavate to fusiform, three-septate, rostrate phragmoconidia, but it can be distinguished by its much shorter, branched, determinate conidiophores....
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PMID: 21177489
PDF is available here.
PDF is available here.
Molecular BioSystems (6)12 2010
Abstract
We researched the role of alternative DNA structure in cytosine methylation using quadruplex DNA as a case study. Our findings from analysis of 2.1 million CpGs in humans, across 12 tissues from the Human Epigenome Project (HEP), revealed a striking correlation within each tissue: CpGs with low meth...
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PMID: 20877913
PDF is available here.
PDF is available here.
Abstract
We show that the Streptococcus thermophilus CRISPR1/Cas system can also naturally acquire spacers from a self-replicating plasmid containing an antibiotic-resistance gene, leading to plasmid loss. Acquired spacers that match antibiotic-resistance genes provide a novel means to naturally select bacte...
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PMID: 21048762
PDF is available here.
PDF is available here.
New Phytologist (188)1 2010
Abstract
We found that most pyrosequencing singletons were artifactual and contained a strongly elevated proportion of insertions compared with natural intra- and interspecific variation. The alternative primers, DNA extraction methods and PCR replicates strongly influenced the richness and community composi...
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PMID: 20636324
PDF is available here.
PDF is available here.
Abstract
We conclude that the large noncoding-DNA content of the V. carteri genomes is best explained by the mutational-hazard hypothesis and speculate that the shift from unicellular to multicellular life in the ancestor that gave rise to V. carteri contributed to a low V. carteri population size and thus a...
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PMID: 20430860
PDF is available here.
PDF is available here.
Abstract
The complete nucleotide sequence of mitochondrial genome of the Great bustard (Otis tarda) was determined by using polymerase chain reaction (PCR) method. The genome is 16,849 bp in size, containing 13 protein-coding, 2 ribosomal and 22 transfer RNA genes. Sequences of the tRNA genes can be folded i...
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PMID: 19823949
PDF is available here.
PDF is available here.
Abstract
In this paper, the complete mitochondrial genome of Acraea issoria (Lepidoptera: Nymphalidae: Heliconiinae: Acraeini) is reported; a circular molecule of 15,245 bp in size. For A. issoria, genes are arranged in the same order and orientation as the complete sequenced mitochondrial genomes of the oth...
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PMID: 20091125
PDF is available here.
PDF is available here.
Abstract
In order to reveal DNA types of aspermic Fasciola forms in Japan, Fasciola specimens obtained from eight prefectures that had not been previously reported were analyzed for DNA of ribosomal internal transcribed spacer 1 (ITS1) and mitochondrial NADH dehydrogenase 1 (ND1) gene. Five combinations in D...
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PMID: 20467211
PDF is available here.
PDF is available here.
Oncology Reports (24)3 2010
Abstract
We identified a new splice variant of ANRIL and introduced it into HeLa cells to uncover functional aspects of ANRIL towards cellular function. For this purpose, we monitored global mRNA expressional changes and conducted gene ontology enrichment. The majority of mRNAs was down-regulated by ANRIL ov...
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PMID: 20664976
PDF is available here.
PDF is available here.
Abstract
We studied co-infections of emerging bacterial pathogens (Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Francisella tularensis) in Ixodes ricinus ticks in Serbia. Using PCR technique, we detected species-specific sequences, rrf-rrl rDNA intergenic spacer for B. burgdorferi s.l., p44...
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PMID: 21073144
PDF is available here.
PDF is available here.
Nature Reviews: Genetics (11)8 2010
Abstract
Most of the human genome consists of non-protein-coding DNA. Recently, progress has been made in annotating these non-coding regions through the interpretation of functional genomics experiments and comparative sequence analysis. One can conceptualize functional genomics analysis as involving a sequ...
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PMID: 20628352
PDF is available here.
PDF is available here.
Abstract
We provide multiple lines of evidence establishing PHF8 as the first mono-methyl histone H4 lysine 20 (H4K20me1) demethylase, with additional activities towards histone H3K9me1 and me2. PHF8 is located around the transcription start sites (TSS) of approximately 7,000 RefSeq genes and in gene bodies...
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PMID: 20622853
PDF is available here.
PDF is available here.
Abstract
We show that an LTR retrotransposon of ERV-9 human endogenous retrovirus located 40-70 kb upstream of the human fetal gamma- and adult beta-globin genes serves a long-range, host function. The ERV-9 LTR contains multiple CCAAT and GATA motifs and competitively recruits a high concentration of NF-Y a...
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PMID: 20615953
PDF is available here.
PDF is available here.
Abstract
We generated a map of DNA methylation from the human brain encompassing 24.7 million of the 28 million CpG sites. From the dense, high-resolution coverage of CpG islands, the majority of methylated CpG islands were shown to be in intragenic and intergenic regions, whereas less than 3% of CpG islands...
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PMID: 20613842
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
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PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
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PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
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PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
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PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
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PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
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PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
New Phytologist (187)2 2010
Abstract
SUMMARY: *The micro-evolutionary mechanisms that drive large-scale radiations are not completely understood, partly because of a shortage of population-level studies aimed at identifying putative causes of rapid evolutionary change. The Dianthus broteri complex, representing the larg...
|
PMID: 20456054
PDF is available here.
PDF is available here.
Abstract
We assessed a noncoding intragenic spacer (IGS) region to compare genotypes found in clinical samples from relapsing fever patients. Although IGS typing was highly discriminatory and resolved 4 East African tick-borne relapsing fever groups from a disease-endemic region in Tanzania, 2 IGS clades wer...
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PMID: 20587177
PDF is available here.
PDF is available here.
Abstract
Despite the significance of diatoms in biomonitoring, many aspects of their biodiversity and geographical distribution are poorly understood. Recent evidence from molecular data has shown that traditional cosmopolitan and euryvalent morphospecies are often heterogeneous, containing cryptic or pseudo...
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PMID: 20097131
PDF is available here.
PDF is available here.
Abstract
Small RNAs (sRNAs) are non-coding transcripts exerting their functions in the cells directly. Identification of sRNAs is a difficult task due to the lack of clear sequence and structural biases. Most sRNAs are identified within genus specific intergenic regions in related genomes. Ho...
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PMID: 20691398
PDF is available here.
PDF is available here.
Archives of Virology (155)6 2010
Abstract
Our results suggest that different genetic lineages of RABV are adapted to different animal species in Brazil....
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PMID: 20401500
PDF is available here.
PDF is available here.
Abstract
We determined five new sequences from Babesia bigemina, B. caballi, B. gibsoni, Theileria orientalis, and T. equi. Together with previously reported sequences of B. bovis, T. annulata, and T. parva, all eight Babesia and Theileria mt genomes are linear molecules with terminal inverted repeats (TIRs)...
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PMID: 20034997
PDF is available here.
PDF is available here.
Abstract
We have now analyzed the regulatory significance of the region upstream of the SHOX gene. By comparative genomic analyses, we identified several conserved non-coding elements, which subsequently were tested in an in ovo enhancer assay in both chicken limb bud and cornea, where SHOX is also expressed...
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PMID: 19997128
PDF is available here.
PDF is available here.
Microbiology (156)Pt 5 2010
Abstract
We describe two CRISPR/CAS systems found in E. coli, following the analysis of 100 strains representative of the species' diversity. Our results substantiate different levels of activity between loci of both CRISPR types, as well as different target preferences and CRISPR relevances for particular g...
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PMID: 20133361
PDF is available here.
PDF is available here.
Abstract
We hypothesized that ACVR2 frameshifts were influenced by DNA sequences surrounding the microsatellite. We constructed plasmids in which exons 3 or 10 of ACVR2 were cloned +1 bp out of frame of enhanced green fluorescent protein (EGFP), allowing -1 bp frameshift to express EGFP. Plasmids were stably...
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PMID: 20140012
PDF is available here.
PDF is available here.