Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
DNA, Viral (0):
Recent article
DNA, Viral
Abstract
| < More recent | Older article > |
New England Journal of Medicine (364)22 2011
Abstract
We compared real-time PCR assays of liquid-saliva and dried-saliva specimens with rapid culture of saliva specimens obtained at birth.
A total of 177 of 34,989 infants (0.5%; 95% confidence interval [CI], 0.4 to 0.6) were positive for CMV, according to at least one of the three metho...
|
PMID: 21631323
PDF is available here.
PDF is available here.
ISME Journal (5)5 2011
Abstract
We describe two complete ssDNA phage genomes that were reconstructed from a viral metagenome from 80 m depth at the Bermuda Atlantic Time-series Study (BATS) site in the northwestern Sargasso Sea and examine their spatial and temporal distributions. Both genomes (SARssφ1 and SARssφ2) exhibited s...
|
PMID: 21124487
PDF is available here.
PDF is available here.
Xenobiotica (41)5 2011
Abstract
We have adapted the HCVpp infection assay with HCVpp harboring a luciferase reporter to a 96-well format and screened a small-molecule compound library to identify inhibitors of HCV entry. Such active viral entry inhibitors have the potential to be first-in-class antiviral drugs that can be incorpor...
|
PMID: 19009270
PDF is available here.
PDF is available here.
Veterinary Microbiology (149)1-2 2011
Abstract
These results differ from what has been reported in in vitro studies, and indicate that different PBMC subpopulations may play different roles in EHV-1 viremia.
Copyright © 2010 Elsevier B.V. All rights reserved....
|
PMID: 21093993
PDF is available here.
PDF is available here.
The Lancet (377)9773 2011
Abstract
We undertook a phase-2 randomised placebo controlled trial in adults awaiting kidney or liver transplantation at the Royal Free Hospital, London, UK. Exclusion criteria were pregnancy, receipt of blood products (except albumin) in the previous 3 months, and simultaneous multiorgan transplantation. 7...
|
PMID: 21481708
PDF is available here.
PDF is available here.
Abstract
Since herpes simplex virus type 2 (HSV-2) antibody tests have become commercially available, an increasing number of persons have learned that they have genital herpes through serologic testing. The course of natural history of HSV-2 in asymptomatic, seropositive persons is uncertain...
|
PMID: 21486977
PDF is available here.
PDF is available here.
Abstract
Abstract
We determined the methylation status of all 110 CpG sites within the viral epigenome in advanced stage III/IV HPV-16-associated head and neck cancers. We found that the viral genome was hypomethylated in the majority of head and neck cancers, in particular within the viral regulatory region, long co...
|
PMID: 21292634
PDF is available here.
PDF is available here.
Abstract
The human neurotropic virus, JC virus (JCV), is the etiologic agent of the fatal demyelinating disease of the central nervous system, Progressive Multifocal Leukoencephalopathy (PML) that is seen primarily in immunodeficient individuals. Productive infection of JCV occurs only in glial cells, and thi...
|
PMID: 21297941
PDF is available here.
PDF is available here.
Abstract
The HPV prevalence rate was lowest among child bearing women aged 25-34 year. Also, personal hygiene is significantly associated with the HPV infection in this area, regardless of age....
|
PMID: 21627383
PDF is available here.
PDF is available here.
Journal of Gastroenterology and Hepatology (26 Suppl 1) 2011
Abstract
We are still facing a large population of young HBV-infected patients in the coming two decades. The study of long-term longitudinal databases has provided deeper insight into the clinical significance of HBV DNA suppression, hepatitis B e antigen (HBeAg) seroconversion and hepatitis B surface antig...
|
PMID: 21199524
PDF is available here.
PDF is available here.
Intervirology (54)1 2011
Abstract
Human herpesvirus 7 (HHV-7) is spread worldwide and has been described as a potential pathogen in immunosuppressed patients. Different clinical manifestations have been described including fever and skin rash; HHV-7 may also be a possible cofactor for cytomegalovirus disease in transplant recipients...
|
PMID: 20689313
PDF is available here.
PDF is available here.
Pediatric Blood & Cancer (55)6 2010
Abstract
We report a case of a 3.5-year-old female with a very high copy number of human herpesvirus 6 (HHV-6) detected by PCR in blood during acute lymphoblastic leukemia induction therapy. The patient was unsuccessfully treated with antiviral drugs. HHV-6 genome was shown to be constitutively integrated in...
|
PMID: 20589623
PDF is available here.
PDF is available here.
Obstetrics & Gynecology (116)6 2010
Abstract
1) discordant (normal Pap and positive HPV) or 2) mildly abnormal (atypical squamous cells of undetermined significance Pap and negative HPV). Analyses included multivariable logistic regression.
For the discordant test results, 54.3% (95% confidence interval [CI] 51-57.6%) of physicians recommended...
|
PMID: 21099599
PDF is available here.
PDF is available here.
Abstract
We detected herpes simplex virus types 1 (HSV-1) and 2 (HSV-2), varicella zoster virus (VZV), and cytomegalovirus (CMV) DNAs in recipient corneal buttons taken at the time of penetrating keratoplasty.
Twenty-seven corneal buttons were obtained from 27 patients (10 men and 17 women), 7 of whom had a...
|
PMID: 20847665
PDF is available here.
PDF is available here.
Virus/Uirusu (60)2 2010
Abstract
Herpes simplex virus (HSV), the prototype of the herpesvirus family, causes a variety of diseases in human. In this review, I focus on the molecular mechanism of HSV infection including recent advance on this research field.
|
PMID: 21488332
PDF is available here.
PDF is available here.
Lab On a Chip (10)22 2010
Abstract
A point-of-care, diagnostic system incorporating a portable thermal cycler and a compact fluorescent detector for real-time, polymerase chain reaction (PCR) on disposable, plastic microfluidic reactors with relatively large reaction volume (ranging from 10 µL to 100 µL) is described. To maintain t...
|
PMID: 20927453
PDF is available here.
PDF is available here.
Abstract
We show that the Streptococcus thermophilus CRISPR1/Cas system can also naturally acquire spacers from a self-replicating plasmid containing an antibiotic-resistance gene, leading to plasmid loss. Acquired spacers that match antibiotic-resistance genes provide a novel means to naturally select bacte...
|
PMID: 21048762
PDF is available here.
PDF is available here.
Abstract
Viral and prokaryotic abundance, production and diversity were determined throughout the water column of the subtropical Atlantic Ocean to assess potential variations in the relation between viruses and prokaryotes. Prokaryotic abundance and heterotrophic activity decreased by one and three orders o...
|
PMID: 20485386
PDF is available here.
PDF is available here.
Abstract
Squamous cell carcinomas of the head and neck (HNSCC) are a frequent diagnosis in anatomic pathology practice. Tobacco use and heavy alcohol consumption are known risk factors for HNSCC but in other cases human papillomavirus (HPV) is linked to carcinogenesis. HPV proteins E6 and E7 promote oncogene...
|
PMID: 20966645
PDF is available here.
PDF is available here.
Abstract
We collected information about demographics, epidemiology, severity of hepatitis B virus-related liver disease, antiviral therapy, response (hepatitis B viral DNA and alanine aminotransferase normalization changes), dose modification, or treatment interruption.
Approximately, 60% of patients enrolle...
|
PMID: 20964259
PDF is available here.
PDF is available here.
Abstract
We report the case of a middle age HIV male, presenting with intestinal occlusion. Rectosigmoidoscopy showed multiple anorectal nodular and ulceronecrotic masses. The biopsy specimens revealed a diffuse polymorphous inflammatory infiltrate in the lamina propria, associated with CD30, CD20, CD3, CD15...
|
PMID: 20861713
PDF is available here.
PDF is available here.
Abstract
Several national and international guidelines have been published in the last years focusing on the problem of how to best treat patients with chronic hepatitis B virus (HBV) infection. Therapy with interferon or nucleos(t)ide analogues has been shown to be most effective in suppressing HBV deoxyrib...
|
PMID: 20960376
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)43 2010
Abstract
We recently determined the structure of a previously unrecognized pol-prim domain (p68N) that docks on Tag, identified the p68N surface that contacts Tag, and demonstrated its vital role in primosome function. Here, we identify the p68N-docking site on Tag by using structure-guided mutagenesis of th...
|
PMID: 20685648
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We developed a method to recover recombinant viruses in which independent selection strategies are used to engineer single-gene replacements. We coupled a mutant SA11 RV encoding a temperature-sensitive (ts) defect in the NSP2 protein with RNAi-mediated degradation of NSP2 mRNAs to isolate a virus c...
|
PMID: 20937889
PDF is available here.
PDF is available here.
Abstract
The recent emergence of a herpes-like virus in both farmed and wild populations of abalone in Victoria, Australia, has been associated with high mortality rates in animals of all ages. Based on viral genome sequence information, a virus-specific real-time TaqMan assay was developed for detection and...
|
PMID: 21166309
PDF is available here.
PDF is available here.
New England Journal of Medicine (363)15 2010
Abstract
We report on delivery of a functional dystrophin transgene to skeletal muscle in six patients with Duchenne's muscular dystrophy. Dystrophin-specific T cells were detected after treatment, providing evidence of transgene expression even when the functional protein was not visualized in skeletal musc...
|
PMID: 20925545
PDF is available here.
PDF is available here.
Abstract
We present an overview of recent research into cellular reprogramming. We focus on the feasibility of microRNA-based strategies for reprogramming somatic cells into pluripotent stem cells, thus obviating the need to introduce viruses or DNA into donor cells, and therefore ameliorating the risks asso...
|
PMID: 20601195
PDF is available here.
PDF is available here.
New Microbiologica (33)4 2010
Abstract
Despite the widespread use of molecular biology techniques, standardized methods for the measurement of HIV-1 proviral DNA are currently lacking and several discordant results are still present in different studies. To assess the clinical meaning of the proviral DNA load, a study group comprising se...
|
PMID: 21213587
PDF is available here.
PDF is available here.
New Microbiologica (33)4 2010
Abstract
We describe a case of an otherwise immunocompetent patient who presented a very high-level asymptomatic polyomavirus JC viruria following long-term steroid therapy....
|
PMID: 21213601
PDF is available here.
PDF is available here.
New Microbiologica (33)4 2010
Abstract
Zoster sine herpete is a particular form of varicella zoster virus (VZV) infection characterized by segmental pain and dysesthesia, without any cutaneous lesions ever becoming perceptible. This report describes the case of a female patient, presenting with intercostal pain associated with a single p...
|
PMID: 21213602
PDF is available here.
PDF is available here.
Clinical Immunology (137)1 2010
Abstract
Abstract
Chronic hepatitis B (CHB) infection remains a major global problem but the recent advances in molecular methods have revolutionized the diagnosis and management of CHB. Hepatitis B virus (HBV) DNA quantitation is the most useful molecular marker for the diagnosis and management of CHB. There is incr...
|
PMID: 20964611
PDF is available here.
PDF is available here.
Ginekologia polska (81)10 2010
Abstract
Development of primary prevention of cervical cancer in other words a vaccination against selected, oncogenic HPV types, entails an increasing importance of epidemiological studies and prevalence of various types of human papilloma virus. The incidence of HPV varies depending on the geographic locat...
|
PMID: 21117301
PDF is available here.
PDF is available here.
Abstract
The persistence of covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) in hepatocytes plays a key role in viral persistence and resistance to therapy. Therefore, quantitative cccDNA measurement is of clinical importance for evaluating the efficacy of antiviral drugs, selecting an appr...
|
PMID: 20691734
PDF is available here.
PDF is available here.
Abstract
Orthopoxvirus monkeypox (MPXV) forms two distinct clades: the MPXV Congo Basin clade viruses are endemic in the Congo Basin, human illness typically presents with symptoms similar to discrete, ordinary smallpox and has a case fatality rate of approximately 10% in unvaccinated populations; the MPXV W...
|
PMID: 20643162
PDF is available here.
PDF is available here.
Abstract
A loop-mediated isothermal amplification (LAMP) assay was developed specifically for detection and differentiation of pseudorabies virus (PRV). One group of primers was designed to detect wild-type strains (i.e., strains with the gE gene) and the other group of primers was designed to detect both PR...
|
PMID: 20691214
PDF is available here.
PDF is available here.
Abstract
We analyzed the genetic relationship between gp160 env sequences from replication competent clonal HIV-1 variants that were isolated from PBMC and from contemporaneous HIV-1 RNA in serum and HIV-1 proviral DNA in PBMC of four longitudinally studied therapy naïve HIV-1 infected individuals. Replicat...
|
PMID: 20638697
PDF is available here.
PDF is available here.
Abstract
We sequenced the long terminal repeats and part of the env region of enFeLVs in domestic cats and five wild species. A total of 305 enFeLV sequences were generated across 17 individuals, demonstrating considerable diversity within two major clades. Distinct proliferations of enFeLVs occurred before...
|
PMID: 20615520
PDF is available here.
PDF is available here.
Abstract
We show that the replication-associated proteins (Rep: a rolling-circle replication initiator protein) encoded by these alphasatellites interact with the Rep and C4 proteins encoded by their helper begomovirus, Cotton leaf curl Rajasthan virus (CLCuRaV), in a yeast two-hybrid assay. Both the alphasa...
|
PMID: 20598726
PDF is available here.
PDF is available here.
Abstract
We characterized the functional domains of BFV BTas. BTas contains two major functional domains: the N-terminal DNA-binding domain (residues 1-133) and the C-terminal activation domain (residues 198-249). The complete BTas responsive regions were mapped to the positions -380/-140 of LTR and 9205/927...
|
PMID: 20615521
PDF is available here.
PDF is available here.
Abstract
Koi herpesvirus (KHV) was identified as being associated with more than one mortality event affecting common carp in Canada. The first was an extensive mortality event that occurred in 2007 in the Kawartha Lakes region, Ontario, affecting Lakes Scugog and Pigeon. Fish had branchial necrosis and hepa...
|
PMID: 20966274
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Abstract
We amplified the full-length viral cDNA sequences of three layers isolates associated with simple hemangioma or coexisting of hemangioma and myeloid leukosis (ML) by PCR. We also obtained some partial sequences of three layer isolates related to hemangioma and one layer isolate from ML case. Then we...
|
PMID: 21090269
PDF is available here.
PDF is available here.
Abstract
To enrich the epidemiologic data of the waterfowl origin avian influenza virus (AIV).
The full genome of A/Muscovy Duck/Fujian/FZ01/2008 (H6N6), which was first isolated from domestic Muscovy duck in Fujian Province in southern China at 2008, was cloned and sequenced by reverse transcription polymer...
|
PMID: 21090254
PDF is available here.
PDF is available here.
Nanotechnology (21)35 2010
Abstract
We demonstrated enhanced localized surface plasmon resonance (SPR) biosensing based on subwavelength gold nanoarrays built on a thin gold film. Arrays of nanogratings (1D) and nanoholes (2D) with a period of 200 nm were fabricated by electron-beam lithography and used for the detection of avian infl...
|
PMID: 20693616
PDF is available here.
PDF is available here.
Abstract
Abstract
We compared the HPV genotype distribution in HIV-1-infected women from Seattle, Washington, USA and Nairobi, Kenya. The reverse line blot assay and DNA sequencing on cervicovaginal lavage (CVL) specimens were carried out.
The most commonly detected HPV types among the women from Seattle were HPV 56,...
|
PMID: 20655263
PDF is available here.
PDF is available here.
Abstract
Overall, 70 (3.8%) of the women were chronically infected with HBV. HBsAg status was strongly linked to SPB, which incurred to 5 (7.3%) of 64 women with circulating HBsAg compared with 28 (1.6%) of 1703 without current HBV infection (odds ratio, 5.2; P=0.007). SPB, however, was linked neither to HBs...
|
PMID: 20605152
PDF is available here.
PDF is available here.
Abstract
We collected 5 specimens (endocervix, upper and lower vagina, perineum, vaginal self-collection) from 2,625 women. Endocervical and self-collected specimens had HR-HPV tests by hc2. All 5 anogenital specimens were tested for 37 HPV genotypes [Linear Array(R), (LA)] from 397 women hc2 positive in end...
|
PMID: 20039323
PDF is available here.
PDF is available here.
Abstract
Despite multimodal therapeutic concepts, advanced localized and high-risk neuroblastoma remains a therapeutic challenge with a long-term survival rate below 50%. Consequently, new modalities for the treatment of neuroblastoma, e.g., oncolytic virotherapy are urgently required. H-1PV...
|
PMID: 20087864
PDF is available here.
PDF is available here.